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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Whats That

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Composition :

TIROFIBAN-5MG

Manufacturer/Marketer :

Aprica Pharmaceuticals Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Aggrifib Injection

Aggrifib Injection belongs to a class of medicines called 'antiplatelets' (blood thinners) used to prevent blood clots. It helps to prevent heart attack and chest pain. It is intended for use with unfractionated heparin and aspirin. A blood clot is a clump of blood that has changed from a liquid to a gel-like or semisolid state. Blood clots are formed to stop bleeding that occurs due to tissue injury. Though blood clots are useful for stopping bleeding, they are harmful when abnormally formed within blood vessels as they block blood vessels and inhibit blood flow to essential organs such as the brain, heart, or lungs.

Aggrifib Injection contains Tirofiban, a platelet aggregation inhibitor which works by preventing platelets (blood cells) from sticking together to form blood clots. Thus, it prevents blood clot formation.

Aggrifib Injection will be administered by a healthcare professional; do not self-administer. Sometimes, Aggrifib Injection may cause common side effects such as bleeding under the skin at the site of injection or into a muscle causing swelling, bleeding after surgery, invisible blood in stool or urine, headache or feeling sick. Most of these side effects of Aggrifib Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Tirofiban or any other medicines, please tell your doctor. Aggrifib Injection is not recommended for children as safety and effectiveness were not established. If you are a pregnant or breastfeeding woman, inform your doctor before receiving Aggrifib Injection. Avoid alcohol consumption with Aggrifib Injection as it may increase the risk of bleeding in the stomach or intestines. If you have a history of stroke or bleeding internally within the last 30 days, avoid receiving Aggrifib Injection.

Uses of Aggrifib Injection

Prevent blood clots, heart attack and chest pain

Directions for Use

Aggrifib Injection will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Aggrifib Injection contains Tirofiban, an antiplatelet which prevents platelets (blood cells) from sticking together to form blood clots. Thus, it is used to prevent blood clots. Also, it helps blood flow to the heart and prevents heart attack and chest pain. Additionally, it may be used in patients whose heart vessels are dilated with a balloon (percutaneous coronary intervention or PCI). It is intended for use with unfractionated heparin and aspirin.

Storage

Keep Aggrifib Injection out of the sight and reach of children.

Drug Warnings

If you are allergic to Tirofiban or any other medicines, please tell your doctor. Aggrifib Injection is not recommended for children as safety and effectiveness were not established. If you are a pregnant or breastfeeding woman, inform your doctor before receiving Aggrifib Injection. Avoid alcohol consumption with Aggrifib Injection as it may increase the risk of bleeding in the stomach or intestines. If you have a history of stroke or bleeding internally within the last 30 days, avoid receiving Aggrifib Injection. If you have had cardiopulmonary resuscitation (CPR), a biopsy, or a procedure to break up kidney stones within the last 2 weeks or have been seriously injured, had a major operation or had an ulcer in the stomach or intestine within the last 3 months, had a recent spinal procedure, have history or symptoms of aortic dissection (splitting of the aorta, main artery), or had a special intravenous line inserted under your collar bone within the last 24 hours, inform your doctor before receiving Aggrifib Injection.

Diet & Lifestyle Advise

  • Avoid making any changes in your diet without first talking to your doctor to avoid medication interactions.
  • Include foods high in antioxidants, such as vegetables, fruits, olive oil, seeds, nuts, cocoa, and red wine, as they may lower the risk of developing blood clots.
  • Adopt an anti-inflammatory diet high in omega-3-rich foods, fruits and vegetables, and vitamin E-rich foods.
  • Drink plenty of fluids as dehydration can thicken blood leading to an increased risk of blood clot formation.
  • Do regular exercise as it helps to dissolve blood clots, especially in obese people.
  • Avoid alcohol consumption as it may increase the risk of bleeding.

Side Effects of Aggrifib Injection

  • Bleeding under the skin at the site of injection or into a muscle causes swelling
  • Bleeding after surgery
  • Invisible blood in stool or urine
  • Headache
  • Feeling sick

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

Author Details

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FAQs

Aggrifib Injection contains Tirofiban, a platelet aggregation inhibitor which works by preventing platelets (blood cells) from sticking together to form blood clots. Thus, it prevents blood clot formation.

Aggrifib Injection is not recommended for patients with severe liver disease. Therefore, if you have any liver disorder, inform your doctor before receiving Aggrifib Injection.

Yes, Aggrifib Injection may cause bleeding. If you notice blood in urine or stool or coughing up blood, please inform your doctor immediately, as these might be signs of internal bleeding.

Drug-Drug Interactions Checker List

  • WARFARIN

Disease/Condition Glossary

Blood clots: A blood clot is a clump of blood that has changed from a liquid to a gel-like or semisolid state. Blood clots are formed to stop bleeding that occurs due to tissue injury. Though blood clots are useful to stop bleeding, they may be harmful when abnormally formed within blood vessels as they block blood vessels and inhibit blood flow to essential organs such as the brain, heart, or lungs and result in serious conditions. The common risk factors for blood clots are obesity, smoking, cancer, family history of blood clots, aged over 65 years, certain birth control pills, or pregnancy. If you experience chest pressure, sudden shortness of breath, or difficulty in breathing, speaking, or seeing, please consult a doctor immediately, as these might be symptoms of blood clots. Quick medication is advised to reduce the risk of serious conditions due to blood clots.

Have a query?

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Alcohol

Unsafe

You are recommended to avoid the consumption of alcohol with Aggrifib Injection as it may increase the risk of bleeding in the stomach or intestines.

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Pregnancy

Consult your doctor

Limited data is available on the effect of Aggrifib Injection in pregnancy. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Aggrifib Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Limited data is available on the effect of Aggrifib Injection on breastfeeding mothers. Hence, if you are a nursing mother, inform your doctor before receiving Aggrifib Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Not applicable

Due to your disease state, you will not be able to drive or operate machinery while receiving Aggrifib Injection.

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Liver

Caution

Aggrifib Injection is not recommended if you have severe liver disease. Therefore, if you have any liver disorder, inform your doctor before receiving Aggrifib Injection.

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Kidney

Caution

If you have kidney disease/condition, inform your doctor before receiving Aggrifib Injection. The dose may be adjusted in patients with severe kidney failure.

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Children

Unsafe

Aggrifib Injection is not recommended for children as the safety and effectiveness were not established.

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