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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Whats That

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Composition

DASATINIB-100MG

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Alsatinib Tablet 30's

Alsatinib Tablet 30's is an anti-cancer medicine used in the treatment of Leukemia. Leukemia, also known as blood cancer, is a cancer of blood cells or blood-forming tissues. It causes excessive production of immature white blood cells by the bone marrow and reduces the body’s ability to fight infections. There are different types of blood cancers. Alsatinib Tablet 30's is used in the treatment of chronic myelogenous leukemia (CML) in patients with chronic, accelerated, or blast phase Ph+ (Philadelphia chromosome-positive) who are resistant or intolerant to prior therapy, in patients with newly diagnosed chronic Ph+ chronic myelogenous leukemia (CML). This medicine is also used in the treatment of Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL).

Alsatinib Tablet 30's contains Dasatinib, which belongs to the class of kinase inhibitors. It works by inhibiting the action of abnormal proteins that cause the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce the further spread to other parts of the body.

Alsatinib Tablet 30's may cause certain side effects, such as skin rash, fatigue, headache, musculoskeletal pain, decreased platelet count, nausea, vomiting, diarrhea, abdominal pain, dizziness, GI bleeding, muscle inflammation, myalgia, and difficulty breathing. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Alsatinib Tablet 30's should be taken as advised by your doctor. Do not take more than the recommended dose of medicine. Your doctor will decide the dose of Alsatinib Tablet 30's based on the severity of your condition.

Alsatinib Tablet 30's should be avoided if you are allergic to it or any other components present in it. Before taking Alsatinib Tablet 30's, caution should be exercised if you have/had liver/kidney disease, gastrointestinal disorders, cardiac problems, and myelosuppression as may cause serious side effects or worsen such conditions. This medicine is known to cause embryo-fetal toxicity. Hence, inform your doctor if you are pregnant or are planning to become pregnant before starting the treatment with Alsatinib Tablet 30's. Breastfeeding should be discontinued in nursing mothers during the treatment.

Uses of Alsatinib Tablet 30's

Philadelphia chromosome-positive chronic myeloid leukemia, Philadelphia chromosome-positive acute lymphoblastic leukemia.

Directions for Use

Take Alsatinib Tablet 30's as advised by your doctor. Do not take more than the prescribed dose of medicine. Swallow the medicine as a whole with a glass of water. Do not chew, crush, or break the medicine.

Medicinal Benefits

Alsatinib Tablet 30's contains Dasatinib, which belongs to the class of kinase inhibitors. It works by inhibiting the action of abnormal proteins (BCR-ABL tyrosine kinase) that cause the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce the further spread to other parts of the body. Alsatinib Tablet 30's is used in the treatment of Philadelphia chromosome-positive chronic myeloid leukemia and acute lymphoblastic leukemia.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Alsatinib Tablet 30's

  • Nausea
  • Diarrhoea
  • Decreased platelet count
  • Fatigue
  • Edema
  • Vomiting
  • Diarrhea
  • Headache
  • Back pain
  • Dizziness
  • Skin rash
  • Difficulty breathing
  • GI bleeding
  • Myalgia

Drug Warnings

Alsatinib Tablet 30's should be avoided if you are allergic to it or any other components present in it. Let your doctor know about your complete medical history, including current medication, to rule out any side effects/interactions. Before taking, inform your doctor if you have liver/kidney disease, diabetes, cardiac problems, increased blood pressure, or gastrointestinal disorders, as the use of Alsatinib Tablet 30's in these patients may cause serious side effects. Alsatinib Tablet 30's may cause myelosuppression, fluid retention, gastrointestinal haemorrhage, QT prolongation, congestive heart failure, Left ventricular dysfunction and Myocardial infarction. This medicine is known to cause embryo-fetal toxicity. Hence, inform your doctor if you are pregnant or are planning to become pregnant before starting the treatment. Breastfeeding should be discontinued in nursing mothers during the treatment. Alsatinib Tablet 30's is given in children above one year of age only if prescribed by the doctor. Avoid alcohol consumption and smoking, as it can lead to serious adverse effects.

Drug-Drug Interactions

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DasatinibMesoridazine
Critical
DasatinibPimozide
Critical

Drug-Drug Interactions

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DasatinibMesoridazine
Critical
How does the drug interact with Alsatinib Tablet:
Using Mesoridazine together with Alsatinib Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Mesoridazine with Alsatinib Tablet is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop any medication without talking to a doctor.
DasatinibPimozide
Critical
How does the drug interact with Alsatinib Tablet:
Using Pimozide together with Alsatinib Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Alsatinib Tablet with Pimozide is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop any medication without talking to a doctor.
DasatinibHalofantrine
Critical
How does the drug interact with Alsatinib Tablet:
Using Halofantrine together with Alsatinib Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Alsatinib Tablet with Halofantrine is not recommended, consult a doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop any medication without doctor's advice.
DasatinibDronedarone
Critical
How does the drug interact with Alsatinib Tablet:
Using dronedarone together with Alsatinib Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Alsatinib Tablet with Dronedarone is not recommended, please consult a doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medication without doctor's advice.
DasatinibCabozantinib
Severe
How does the drug interact with Alsatinib Tablet:
Using Cabozantinib together with Alsatinib Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Cabozantinib with Alsatinib Tablet together can result in an interaction, but it can be taken if a doctor has advised it. Consult a doctor if you experience dizziness, fainting, breathlessness, or heart palpitations. Do not stop using any medications without talking to a doctor.
DasatinibLeflunomide
Severe
How does the drug interact with Alsatinib Tablet:
Using leflunomide together with Alsatinib Tablet may increase the risk of infections.

How to manage the interaction:
Although there is a possible interaction between Leflunomide and Alsatinib Tablet, you can take these medicines together if prescribed by a doctor. If you notice any of these symptoms - like body sores, red or inflamed skin, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, fever, and discomfort or burning while urinating, make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
DasatinibAcalabrutinib
Severe
How does the drug interact with Alsatinib Tablet:
Using Alsatinib Tablet together with acalabrutinib may increase the risk of bleeding.

How to manage the interaction:
Although taking Alsatinib Tablet and Acalabrutinib together can cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these symptoms - like difficulty with blood clotting, bleeding, complications, bruising, feeling dizzy or lightheaded, having red or black stools, coughing up blood, experiencing severe headaches, weakness, or vomiting - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
DasatinibVoriconazole
Severe
How does the drug interact with Alsatinib Tablet:
Coadministration of Alsatinib Tablet with Voriconazole may significantly increase the blood levels of Alsatinib Tablet which increases risk of side effects.

How to manage the interaction:
Although taking Alsatinib Tablet and Voriconazole together may result in an interaction, they can be taken together if a doctor prescribes it. However, if you experience dizziness, shortness of breath, heart palpitations, muscle pain, pain or burning during urination consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
DasatinibAnistreplase
Severe
How does the drug interact with Alsatinib Tablet:
Using Alsatinib Tablet together with Anistreplase may increase the risk of bleeding.

How to manage the interaction:
Taking Alsatinib Tablet with Anistreplase together can result in an interaction, but it can be taken if a doctor has advised it. If you notice dizziness;; red or black, tarry stools; severe headache; and weakness contact a doctor. Do not discontinue any medications without consulting a doctor.
DasatinibEfavirenz
Severe
How does the drug interact with Alsatinib Tablet:
Using Efavirenz together with Alsatinib Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Efavirenz with Alsatinib Tablet together can result in an interaction, but it can be taken if a doctor has advised it. Consult a doctor if you experience dizziness, breathlessness, or heart palpitations. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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DASATINIB-100MGGrapefruit and Grapefruit Juice
Severe

Drug-Food Interactions

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DASATINIB-100MGGrapefruit and Grapefruit Juice
Severe
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Grapefruit juice can significantly increase the blood levels and effects of Alsatinib Tablet. Avoid consumption of Grapefruit juice with Alsatinib Tablet. However, contact a doctor if you experience dizziness, shortness of breath, heart palpitations, pain, or burning during urination.

Diet & Lifestyle Advise

  • After beginning your treatment, several dietary adjustments can help you control side effects.
  • Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
  • Plant-based proteins are among the greatest meals to take during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans, and legumes.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast and fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Alsatinib Tablet 30's Substitute

Substitutes safety advice
  • Invista 100 mg Tablet 10's

    by Others

    131.58per tablet
  • Daslemia 100mg Tablet 30's

    by Others

    102.36per tablet
  • Spnib 100 Tablet 30's

    by Others

    92.96per tablet
  • Dasatib 100 mg Tablet 30's

    by Others

    8081.10per tablet
  • Dasamyl 100 mg Tablet 30's

    by Others

    3111.90per tablet

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • PANTOPRAZOLE
  • KETOCONAZOLE
  • ESOMEPRAZOLE
  • RITONAVIR
  • CLARITHROMYCIN
  • ERYTHROMYCIN
  • PHENYTOIN
  • RIFAMPICIN
  • CARBAMAZEPINE
  • ALUMINIUM HYDROXIDE

Special Advise

  • A blood test, such as LFT and RFT, should be performed to check for liver/kidney function.
  • Weekly blood tests should be done during the treatment to check for CBC (Complete blood count).
  • An ECG and ECHO should be done in patients taking Alsatinib Tablet 30's to check for any signs of cardiac problems.

Disease/Condition Glossary

Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia: Leukemia, also known as blood cancer, is a cancer of blood cells or blood-forming tissues. It causes excessive production of immature white blood cells by the bone marrow and reduces the body’s ability to fight infections. Chronic Myelogenous Leukemia is a type of blood cancer that originates in the myeloid cells or stem cells in your bone marrow. Ph+ chronic myeloid leukemia is a common form of CML that occurs when specific chromosomes swap position. This causes a chromosome abnormality, creating the Philadelphia chromosome. The abnormal chromosomes produce an abnormal protein called Bcr-Abl tyrosine kinase, which then triggers a signal to produce abnormal white blood cells in the bone marrow. Symptoms may include fatigue, fever, weight loss, and loss of appetite.

Philadelphia chromosome-positive (Ph+) Acute Lymphoblastic Leukemia (ALL): ALL is a type of blood cancer that primarily affects your blood and bone marrow. It mainly targets the white blood cells which can interfere with your body’s ability to combat infections. Ph+ Acute Lymphoblastic Leukemia is a form of ALL that occurs when specific chromosomes swap position. This causes a chromosome abnormality, creating the Philadelphia chromosome. The abnormal chromosomes produce a BCR-ABL tyrosine kinase protein, which triggers a signal to produce abnormal white blood cells in the bone marrow. Symptoms may include fever, weight loss, abnormal blood cell count, bruising, and loss of appetite.

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