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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

About Dasatib 100 mg Tablet 30's

Dasatib 100 mg Tablet 30's is an anti-cancer medicine used in the treatment of Leukemia. Leukemia, also known as blood cancer, is a cancer of blood cells or blood-forming tissues. It causes excessive production of immature white blood cells by the bone marrow and reduces the body’s ability to fight infections. There are different types of blood cancers. Dasatib 100 mg Tablet 30's is used in the treatment of chronic myelogenous leukemia (CML) in patients with chronic, accelerated, or blast phase Ph+ (Philadelphia chromosome-positive) who are resistant or intolerant to prior therapy, in patients with newly diagnosed chronic Ph+ chronic myelogenous leukemia (CML). This medicine is also used in the treatment of Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL).

Dasatib 100 mg Tablet 30's contains Dasatinib, which belongs to the class of kinase inhibitors. It works by inhibiting the action of abnormal proteins that cause the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce the further spread to other parts of the body.

Dasatib 100 mg Tablet 30's may cause certain side effects, such as skin rash, fatigue, headache, musculoskeletal pain, decreased platelet count, nausea, vomiting, diarrhea, abdominal pain, dizziness, GI bleeding, muscle inflammation, myalgia, and difficulty breathing. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Dasatib 100 mg Tablet 30's should be taken as advised by your doctor. Do not take more than the recommended dose of medicine. Your doctor will decide the dose of Dasatib 100 mg Tablet 30's based on the severity of your condition.

Dasatib 100 mg Tablet 30's should be avoided if you are allergic to it or any other components present in it. Before taking Dasatib 100 mg Tablet 30's , caution should be exercised if you have/had liver/kidney disease, gastrointestinal disorders, cardiac problems, and myelosuppression as may cause serious side effects or worsen such conditions. This medicine is known to cause embryo-fetal toxicity. Hence, inform your doctor if you are pregnant or are planning to become pregnant before starting the treatment with Dasatib 100 mg Tablet 30's . Breastfeeding should be discontinued in nursing mothers during the treatment.

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Whats That

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Non returnable*
COD available

Online payment accepted

Composition

DASATINIB-100MG

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

Uses of Dasatib 100 mg Tablet 30's

Philadelphia chromosome-positive chronic myeloid leukemia, Philadelphia chromosome-positive acute lymphoblastic leukemia.

Medicinal Benefits

Dasatib 100 mg Tablet 30's contains Dasatinib, which belongs to the class of kinase inhibitors. It works by inhibiting the action of abnormal proteins (BCR-ABL tyrosine kinase) that cause the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce the further spread to other parts of the body. Dasatib 100 mg Tablet 30's is used in the treatment of Philadelphia chromosome-positive chronic myeloid leukemia and acute lymphoblastic leukemia.

Side Effects of Dasatib 100 mg Tablet 30's

  • Nausea
  • Diarrhoea
  • Decreased platelet count
  • Fatigue
  • Edema
  • Vomiting
  • Diarrhea
  • Headache
  • Back pain
  • Dizziness
  • Skin rash
  • Difficulty breathing
  • GI bleeding
  • Myalgia

Directions for Use

Take Dasatib 100 mg Tablet 30's as advised by your doctor. Do not take more than the prescribed dose of medicine. Swallow the medicine as a whole with a glass of water. Do not chew, crush, or break the medicine.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Dasatib 100 mg Tablet 30's should be avoided if you are allergic to it or any other components present in it. Let your doctor know about your complete medical history, including current medication, to rule out any side effects/interactions. Before taking, inform your doctor if you have liver/kidney disease, diabetes, cardiac problems, increased blood pressure, or gastrointestinal disorders, as the use of Dasatib 100 mg Tablet 30's in these patients may cause serious side effects. Dasatib 100 mg Tablet 30's may cause myelosuppression, fluid retention, gastrointestinal haemorrhage, QT prolongation, congestive heart failure, Left ventricular dysfunction and Myocardial infarction. This medicine is known to cause embryo-fetal toxicity. Hence, inform your doctor if you are pregnant or are planning to become pregnant before starting the treatment. Breastfeeding should be discontinued in nursing mothers during the treatment. Dasatib 100 mg Tablet 30's is given in children above one year of age only if prescribed by the doctor. Avoid alcohol consumption and smoking, as it can lead to serious adverse effects.

Therapeutic Class

ANTINEOPLASTIC

Drug-Drug Interactions

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DasatinibMesoridazine
Critical
DasatinibPimozide
Critical

Drug-Drug Interactions

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DasatinibMesoridazine
Critical
How does the drug interact with Dasatib 100 mg Tablet 30's :
Using Mesoridazine together with Dasatib 100 mg Tablet 30's can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Mesoridazine with Dasatib 100 mg Tablet 30's is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop any medication without talking to a doctor.
DasatinibPimozide
Critical
How does the drug interact with Dasatib 100 mg Tablet 30's :
Using Pimozide together with Dasatib 100 mg Tablet 30's can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Dasatib 100 mg Tablet 30's with Pimozide is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop any medication without talking to a doctor.
DasatinibDronedarone
Critical
How does the drug interact with Dasatib 100 mg Tablet 30's :
Using dronedarone together with Dasatib 100 mg Tablet 30's can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Dasatib 100 mg Tablet 30's with Dronedarone is not recommended, please consult a doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medication without doctor's advice.
DasatinibHalofantrine
Critical
How does the drug interact with Dasatib 100 mg Tablet 30's :
Using Halofantrine together with Dasatib 100 mg Tablet 30's can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Dasatib 100 mg Tablet 30's with Halofantrine is not recommended, consult a doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop any medication without doctor's advice.
DasatinibFosphenytoin
Severe
How does the drug interact with Dasatib 100 mg Tablet 30's :
Using Dasatib 100 mg Tablet 30's with Fosphenytoin may significantly reduce the blood levels of Dasatib 100 mg Tablet 30's .

How to manage the interaction:
There may be a possibility of interaction between Fosphenytoin and Dasatib 100 mg Tablet 30's , but it can be taken if prescribed by a doctor. However, if you experience side effects like unusual bleeding, swelling, palpitations, shortness of breath, chest pain or tightness, or heart rhythm changes, contact a doctor immediately. Do not stop using any medications without a doctor's advice.
DasatinibUrokinase
Severe
How does the drug interact with Dasatib 100 mg Tablet 30's :
Combining Dasatib 100 mg Tablet 30's with Urokinase can increase the risk and severity of bleeding and hemorrhage.

How to manage the interaction:
Co-administration of Urokinase with Dasatib 100 mg Tablet 30's can result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these signs, it's important to contact a doctor right away: bleeding, problems, bruising, feeling dizzy or lightheaded, stools that are red or black and sticky, intense headache, weakness, bleeding, or vomiting. Do not discontinue any medications without consulting a doctor.
DasatinibThioridazine
Severe
How does the drug interact with Dasatib 100 mg Tablet 30's :
Using thioridazine together with Dasatib 100 mg Tablet 30's can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Dasatib 100 mg Tablet 30's with Thioridazine together can result in an interaction, but it can be taken if a doctor has advised it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
DasatinibAnagrelide
Severe
How does the drug interact with Dasatib 100 mg Tablet 30's :
Using Anagrelide together with Dasatib 100 mg Tablet 30's can increase the risk of an irregular heart rhythm.

How to manage the interaction:
There may be a possibility of interaction between Dasatib 100 mg Tablet 30's and Anagrelide, but it can be taken if prescribed by a doctor. If you have symptoms like fainting, dizziness, breathlessness, or heart palpitations, consult a doctor. Do not stop using any medications without a doctor's advice.
DasatinibAcalabrutinib
Severe
How does the drug interact with Dasatib 100 mg Tablet 30's :
Using Dasatib 100 mg Tablet 30's together with acalabrutinib may increase the risk of bleeding.

How to manage the interaction:
Although taking Dasatib 100 mg Tablet 30's and Acalabrutinib together can cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these symptoms - like difficulty with blood clotting, bleeding, complications, bruising, feeling dizzy or lightheaded, having red or black stools, coughing up blood, experiencing severe headaches, weakness, or vomiting - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
DasatinibSotalol
Severe
How does the drug interact with Dasatib 100 mg Tablet 30's :
Using Sotalol together with Dasatib 100 mg Tablet 30's can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Although there is a possible interaction between Sotalol and Dasatib 100 mg Tablet 30's , you can take these medicines together if prescribed by a doctor. If you experience dizziness, shortness of breath, or heart palpitations consult a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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DASATINIB-100MGGrapefruit and Grapefruit Juice
Severe

Drug-Food Interactions

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DASATINIB-100MGGrapefruit and Grapefruit Juice
Severe
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Grapefruit juice can significantly increase the blood levels and effects of Dasatib 100 mg Tablet 30's . Avoid consumption of Grapefruit juice with Dasatib 100 mg Tablet 30's . However, contact a doctor if you experience dizziness, shortness of breath, heart palpitations, pain, or burning during urination.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • PANTOPRAZOLE
  • KETOCONAZOLE
  • ESOMEPRAZOLE
  • RITONAVIR
  • CLARITHROMYCIN
  • ERYTHROMYCIN
  • PHENYTOIN
  • RIFAMPICIN
  • CARBAMAZEPINE
  • ALUMINIUM HYDROXIDE

Diet & Lifestyle Advise

  • After beginning your treatment, several dietary adjustments can help you control side effects.
  • Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
  • Plant-based proteins are among the greatest meals to take during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans, and legumes.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast and fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

Special Advise

  • A blood test, such as LFT and RFT, should be performed to check for liver/kidney function.
  • Weekly blood tests should be done during the treatment to check for CBC (Complete blood count).
  • An ECG and ECHO should be done in patients taking Dasatib 100 mg Tablet 30's to check for any signs of cardiac problems.

Disease/Condition Glossary

Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia: Leukemia, also known as blood cancer, is a cancer of blood cells or blood-forming tissues. It causes excessive production of immature white blood cells by the bone marrow and reduces the body’s ability to fight infections. Chronic Myelogenous Leukemia is a type of blood cancer that originates in the myeloid cells or stem cells in your bone marrow. Ph+ chronic myeloid leukemia is a common form of CML that occurs when specific chromosomes swap position. This causes a chromosome abnormality, creating the Philadelphia chromosome. The abnormal chromosomes produce an abnormal protein called Bcr-Abl tyrosine kinase, which then triggers a signal to produce abnormal white blood cells in the bone marrow. Symptoms may include fatigue, fever, weight loss, and loss of appetite.

Philadelphia chromosome-positive (Ph+) Acute Lymphoblastic Leukemia (ALL): ALL is a type of blood cancer that primarily affects your blood and bone marrow. It mainly targets the white blood cells which can interfere with your body’s ability to combat infections. Ph+ Acute Lymphoblastic Leukemia is a form of ALL that occurs when specific chromosomes swap position. This causes a chromosome abnormality, creating the Philadelphia chromosome. The abnormal chromosomes produce a BCR-ABL tyrosine kinase protein, which triggers a signal to produce abnormal white blood cells in the bone marrow. Symptoms may include fever, weight loss, abnormal blood cell count, bruising, and loss of appetite.

Dasatib 100 mg Tablet 30's Substitute

Substitutes safety advice
  • Invista 100 mg Tablet 10's

    131.58per tablet
  • Daslemia 100mg Tablet 30's

    102.36per tablet
  • Spnib 100 Tablet 30's

    92.96per tablet
  • Dasamyl 100 mg Tablet 30's

    3111.90per tablet
  • Alsatinib Tablet 30's

    by AYUR

    79.24per tablet
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