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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Non returnable*
COD available

Online payment accepted

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Whats That

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Composition :

FOSAPREPITANT-150MG

Manufacturer/Marketer :

Aureate Healthcare

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Amitant-IV Injection

Amitant-IV Injection belongs to a class of drugs called anti-emetics. It is used in combination with other medicines to prevent nausea and vomiting caused by chemotherapy (anti-cancer medicines). Nausea is a feeling of uneasiness in the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth.

Amitant-IV Injection contains Fosaprepitant, a neurokinin 1 (NK1) receptor antagonist which is converted to aprepitant in the body. It works by blocking neurokinin 1 receptors (causes a feeling of sickness) present in the vomiting centre in the brain. Thus, it helps prevent nausea and vomiting. 

Amitant-IV Injection will be administered by a healthcare professional; do not self-administer. In some cases, Amitant-IV Injection may cause common side effects such as headache, hiccups, tiredness, loss of appetite, indigestion, and constipation. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, consult your doctor immediately. 

If you are allergic to Fosaprepitant or other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before receiving Amitant-IV Injection. Drive only if you are alert after receiving Amitant-IV Injection. If you are taking other prescription or non-prescription medicines, inform your doctor before receiving Amitant-IV Injection.

Uses of Amitant-IV Injection

Chemotherapy-induced nausea and vomiting

Directions for Use

Amitant-IV Injection will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Amitant-IV Injection contains Fosaprepitant, an anti-emetic (a drug used to treat nausea and vomiting) which is converted to aprepitant in the body. It works by blocking the action of a natural substance in the brain called neurokinin that causes nausea and vomiting. Thus, it helps prevent nausea and vomiting caused by anti-cancer medicines.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Amitant-IV Injection

  • Headache
  • Hiccups
  • Tiredness
  • Loss of appetite
  • Indigestion
  • Constipation

Drug Warnings

If you are allergic to Fosaprepitant or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before receiving Amitant-IV Injection. Drive only if you are alert after receiving Amitant-IV Injection. If you are taking any other prescription or non-prescription medicines, inform your doctor before receiving Amitant-IV Injection. If you are using warfarin (blood thinner), your doctor may recommend blood tests after you receive Amitant-IV Injection to check your blood clotting.

Drug-Drug Interactions

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FosaprepitantCisapride
Critical
FosaprepitantEliglustat
Critical

Drug-Drug Interactions

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FosaprepitantCisapride
Critical
How does the drug interact with Amitant-IV Injection:
Coadministration of Amitant-IV Injection with Cisapride can increase the levels of Cisapride in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Amitant-IV Injection with Cisapride together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FosaprepitantEliglustat
Critical
How does the drug interact with Amitant-IV Injection:
When Amitant-IV Injection is taken with Eliglustat, can increase Eliglustat levels in the body. This can increase the risk or severity of side effects.

How to manage the interaction:
There may be a possibility of interaction between Amitant-IV Injection and Eliglustat, but it can be taken if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FosaprepitantPimozide
Critical
How does the drug interact with Amitant-IV Injection:
When Pimozide is taken with Amitant-IV Injection, it can increase the Pimozide levels in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Amitant-IV Injection with Pimozide is not recommended, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, prolonged diarrhea, or vomiting, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FosaprepitantTerfenadine
Critical
How does the drug interact with Amitant-IV Injection:
When Amitant-IV Injection is taken with Terfenadine, it can lower the rate at which Amitant-IV Injection is broken down and increases its levels in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Amitant-IV Injection and Terfenadine together is generally avoided as it can show an interaction, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms like Chest discomfort, Shortness of breath, Weakness, or palpitations, it's important to call your doctor right away - they can be serious heart problems. Do not discontinue any medications without consulting a doctor.
FosaprepitantFlibanserin
Critical
How does the drug interact with Amitant-IV Injection:
Coadministration of Amitant-IV Injection with Flibanserin can increase the levels of Flibanserin in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Amitant-IV Injection with Flibanserin together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of headaches, irritation, confusion, edema, fatigue, palpitations, or constipation, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
FosaprepitantAstemizole
Critical
How does the drug interact with Amitant-IV Injection:
Coadministration of Amitant-IV Injection with Astemizole can increase the levels of Astemizole in the body. This increases the risk or severity of side effects like irregular heart rhythms.

How to manage the interaction:
Taking Amitant-IV Injection with Astemizole together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FosaprepitantLomitapide
Critical
How does the drug interact with Amitant-IV Injection:
When Amitant-IV Injection is taken with Lomitapide, it can increase the levels of Lomitapide. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Amitant-IV Injection with Lomitapide together is not recommended as it can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms - diarrhea, nausea, vomiting, pain, discomfort, indigestion, constipation, liver damage, fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, dark colored urine, bleeding or vomiting - make sure to call your doctor right away. Do not stop using any medications without first talking to your doctor.
FosaprepitantCilostazol
Severe
How does the drug interact with Amitant-IV Injection:
Coadministration of Amitant-IV Injection with Cilostazol can increase the levels of Cilostazol in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Amitant-IV Injection with Cilostazol together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or nausea, diarrhea, bleeding, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FosaprepitantHydrocodone
Severe
How does the drug interact with Amitant-IV Injection:
Coadministration of Amitant-IV Injection with Hydrocodone can increase the levels of Hydrocodone in the body. This increases the risk or severity of side effects.

How to manage the interaction:
There may be a possibility of interaction between Amitant-IV Injection and Hydrocodone, but it can be taken if prescribed by a doctor. However, if you experience sudden dizziness, fainting, confusion, excessive drowsiness, slow heart rate, or shallow or difficult breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FosaprepitantRanolazine
Severe
How does the drug interact with Amitant-IV Injection:
When Amitant-IV Injection is taken with Ranolazine, can increase the levels of Ranolazine in the body. This can increase the risk or severity of side effects like irregular heart rhythms.

How to manage the interaction:
Taking Fosamprepitant with Ranolazine can lead to an interaction, please consult a doctor before taking it. They can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats. Do not stop taking any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy and low-fat diet that includes lots of fruits and vegetables, skinless poultry, lean meats, nuts, fish, whole grains, and plant-based oils, especially in small portions, as it will be easy for digestion.
  • Avoid eating over-sweet food and include more salty food, especially if you have been vomiting. 
  • Increase the intake of fluids. Drink a small amount of water after small intervals to stay hydrated. 
  • Avoid taking greasy or oily foods, as these foods trigger nausea and vomiting. 
  • If the smell of food makes you feel sick (vomit), do not cook food, as it may worsen your condition. Let someone else do the cooking or use prepared food from the freezer.

Habit Forming

No

Therapeutic Class

ANTIEMETICS

Amitant-IV Injection Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Amitant-IV Injection works by blocking the action of a natural substance in the brain called neurokinin that causes nausea and vomiting. Thus, it helps prevent nausea and vomiting caused by anti-cancer medicines.

Amitant-IV Injection may cause constipation as a common side effect. However, if the condition persists or worsens, please consult your doctor.

You are advised not to take hormonal birth control medicines such as birth control pills, implants, skin patches, and certain intrauterine devices (IUDs) as they may not work properly when taken together with Amitant-IV Injection. Therefore, you are recommended to use another or additional non-hormonal form of birth control method during treatment with Amitant-IV Injection and for up to 1 month after using Amitant-IV Injection.

Drug-Drug Interactions Checker List

  • PIMOZIDE
  • ASTEMIZOLE
  • TERFENADINE
  • CISAPRIDE
  • TACROLIMUS
  • EVEROLIMUS
  • CYCLOSPORINE
  • SIROLIMUS
  • FENTANYL
  • ALFENTANIL
  • QUINIDINE
  • ETOPOSIDE
  • IRINOTECAN
  • IFOSFAMIDE
  • ACENOCOUMAROL
  • WARFARIN
  • CLARITHROMYCIN
  • TELITHROMYCIN
  • RIFAMPICIN
  • PHENYTOIN
  • CARBAMAZEPINE
  • TRIAZOLAM
  • PHENOBARBITAL
  • MIDAZOLAM
  • KETOCONAZOLE
  • VORICONAZOLE
  • POSACONAZOLE
  • ITRACONAZOLE
  • NEFAZODONE
  • DILTIAZEM
  • DEXAMETHASONE
  • ALPRAZOLAM
  • TOLBUTAMIDE

Disease/Condition Glossary

Nausea and vomiting: Nausea is an uneasiness in the stomach that usually precedes vomiting. Vomiting, on the other hand, is a normal bodily response in which a person desires to evacuate stomach contents from the mouth aggressively. In brief, nausea and vomiting are symptoms of a variety of disorders, including infections, motion sickness, an early stage of pregnancy, and gastroparesis (slow stomach emptying). Vomiting is controlled by a receptor in the brain known as the chemoreceptor trigger zone (CTZ). After chemotherapy and radiation therapy, nausea and vomiting are common side effects. It can also arise as a side effect of an operation or surgery. Controlling vomiting and nausea in cancer patients is critical for conducting daily tasks. It can cause mental abnormalities, lack of appetite, malnutrition, and dehydration if not managed.

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