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Manufacturer/Marketer :

Zydus Healthcare Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

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About Amlodac D Tablet

Amlodac D Tablet belongs to the class of medication called 'anti-hypertensive drugs', primarily used to treat hypertension (high blood pressure). Hypertension is a medical condition in which the blood exerts high pressure (force exerted by circulating blood) against the blood vessel's walls. This condition makes the heart work harder in pumping blood to the whole body. Hypertension can cause severe health complications, including stroke, heart failure, heart attack and kidney failure.

Amlodac D Tablet consists of Amlodipine and Indapamide.  Amlodipine relaxes blood vessels so that blood passes through them easily, thereby lowering blood pressure. Indapamide inhibits excess salt absorption in the body, resulting in increased chloride, sodium, and water excretion through urine. This diuresis process (increased urine production) and excess salts and fluid removal help lower blood pressure. 

The common side effects of Amlodac D Tablet include nausea, stomach pain, headache, sleepiness, ankle swelling, flushing (warm sensation in the face, ears, neck, and trunk), palpitations (pounding heartbeat), constipation, muscle pain, and tiredness. Most of these side effects resolve gradually over time and do not usually require medical attention. However, if you notice any side effects that are not manageable, it is advised to consult your doctor.

Try not to stop taking this medicine on your own. Stopping Amlodac D Tablet may worsen your condition and increase the risk of a heart attack. Tell your doctor if you are sensitive to Amlodac D Tablet , have any kidney/liver diseases, or have heart problems like aortic/mitral stenosis (reduced blood flow from the left atrium to the left ventricle due to narrowing of the mitral valve). Amlodac D Tablet is not recommended for use in pregnancy and breastfeeding. Amlodac D Tablet may cause dizziness; hence it is advised to drive only when you are alert.

Uses of Amlodac D Tablet

High blood pressure (hypertension)

Directions for Use

Swallow this medicine as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

Amlodac D Tablet is composed of two medicines, namely: Amlodipine and Indapamide. Amlodipine belongs to the class of calcium channel blockers that relaxes blood vessels so that blood passes through them easily, lowering blood pressure. Indapamide is a thiazide diuretic that inhibits excess salt absorption in the body, resulting in increased chloride, sodium, and water excretion through urine. This diuresis process (increased urine production) and excess salts and fluid removal help lower blood pressure.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not use Amlodac D Tablet if you are allergic to any of its components. Let your doctor know if you have any history of severe kidney or liver diseases, low potassium levels (hypokalaemia), chest pain (angina), poor blood circulation or controlled heart failure, first-degree heart block, diabetes, thyrotoxicosis (a condition caused by an overactive thyroid gland), liver problems and adrenal gland diseases. Let your doctor know if you have anuria (kidneys aren't producing urine), fluid or electrolyte imbalance, lupus erythematosus (an autoimmune inflammatory disease-causing scaly red patches on the skin), gout, abnormal heart rhythms, thyroid disorders or asthma. Consult your doctor if you are pregnant or breastfeeding. Amlodac D Tablet can increase the chances of light-headedness, so rise slowly if you are sitting/lying and avoid operating any machine or doing any work that needs mental alertness. Amlodac D Tablet is not recommended in people less than 18 years of age.

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
IndapamideProtriptyline
Critical

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
How does the drug interact with Amlodac D Tablet:
Using Amlodac D Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Amlodac D Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
IndapamideProtriptyline
Critical
How does the drug interact with Amlodac D Tablet:
Taking Protriptyline along with Amlodac D Tablet can lead to serious heart problems.

How to manage the interaction:
Taking Protriptyline with Amlodac D Tablet is not recommended, but can be taken if prescribed by the doctor.
IndapamideDroperidol
Critical
How does the drug interact with Amlodac D Tablet:
Taking Droperidol with Amlodac D Tablet can lead to severe heart problems.

How to manage the interaction:
Taking Droperidol with Amlodac D Tablet is not recommended, but can be taken if prescribed by the doctor.
IndapamideThioridazine
Critical
How does the drug interact with Amlodac D Tablet:
Taking Amlodac D Tablet with Thioridazine can increase the risk of heart problems.

How to manage the interaction:
Taking Thioridazine with Amlodac D Tablet is not recommended, but can be taken if prescribed by the doctor.
AmlodipineTizanidine
Severe
How does the drug interact with Amlodac D Tablet:
Co-administration of Tizanidine and Amlodac D Tablet can increase the risk or severity of developing side effects like low blood pressure.

How to manage the interaction:
Although co-administration of Amlodac D Tablet with tizanidine can result in an interaction, it can be taken when a doctor has advised it. However, if you experience headache, dizziness, palpitations, or irregular heart rate while taking these drugs, contact the doctor immediately. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not discontinue any medications without consulting the doctor.
AmlodipineIdelalisib
Severe
How does the drug interact with Amlodac D Tablet:
Coadministration of Amlodac D Tablet and Idelalisib may raise Amlodac D Tablet levels in the blood this may lead to serious side effects (irregular heart rhythm, fluid retention, swelling, heart failure, and abnormally low blood pressure).

How to manage the interaction:
Although taking Amlodac D Tablet with idelalisib can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness or fainting, sudden, unexplained weight gain, swelling of the hands, ankles, or feet, chest discomfort, or trouble breathing while taking these drugs, consult the doctor. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not stop using any medications without a doctor's advice.
AmlodipinePrimidone
Severe
How does the drug interact with Amlodac D Tablet:
Using Amlodac D Tablet and primidone together may lower Amlodac D Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Amlodac D Tablet with primidone can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineLemborexant
Severe
How does the drug interact with Amlodac D Tablet:
Coadministration of lemborexant and Amlodac D Tablet may increase the blood levels of lemborexant.

How to manage the interaction:
Although co-administration of Amlodac D Tablet with Lemborexant can result in an interaction, it can be taken if a doctor has advised it. However, consult your doctor if you experience abnormal sleep patterns, worsening of depression, changes in heartbeat, or headache. Do not discontinue any medications without consulting a doctor.
AmlodipineNitisinone
Severe
How does the drug interact with Amlodac D Tablet:
Coadministration of Amlodac D Tablet and Nitisinone may increase the blood levels and effects of Nitisinone.

How to manage the interaction:
Taking Nitisinone with Amlodac D Tablet together can result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms or if you feel unwell after taking your medication, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice.
AmlodipineSirolimus
Severe
How does the drug interact with Amlodac D Tablet:
Co-administration of Amlodac D Tablet can make Sirolimus may increase the risk of angioedema (a condition associated with swelling of the face, eyes, lips, tongue, throat, and occasionally also the hands and feet).

How to manage the interaction:
There may be a possibility of interaction between Amlodac D Tablet and Sirolimus, but it can be taken if prescribed by a doctor. However, consult the doctor if you notice any swelling of the face, eyes, lips, tongue, throat, hands and feet or have trouble breathing or swallowing. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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AMLODIPINE-5MG+INDAPAMIDE-1.5MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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AMLODIPINE-5MG+INDAPAMIDE-1.5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit, Grapefruit Juice

How to manage the interaction:
Consumption of grapefruit and grapefruit juice along with Indapamide and Amlodipine the levels of Indapamide and Amlodipine in your bloodstream may drop. Avoid consuming a lot of grapefruit and grapefruit juice when using Amlodac D Tablet, instead, take it with water. As a result, your body will absorb the drug more easily.

Diet & Lifestyle Advise

  • Keep your weight under control with a body mass index (BMI) between 19.5 and 24.9.
  • Quit smoking to lower the risk of heart disease. 
  • Avoid chronic stress, as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress.
  • Monitor your blood pressure daily, and if you notice any fluctuations frequently, please get in touch with your doctor immediately.
  • Try including heart-healthy omega-3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oils like olive oil, soybean oil, canola oil, and coconut oil that help in lowering your elevated blood pressure.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS

Amlodac D Tablet Substitute

Substitutes safety advice
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  • Natrilam 1.5 mg/5 mg Tablet 10's

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    16.20per tablet

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Amlodac D Tablet is recommended to use in dose and duration as advised by the doctor. Do not stop taking Amlodac D Tablet on your own, as it may lead to a sudden rise in blood pressure and increases the risk of heart attack and stroke.

Amlodac D Tablet can cause dehydration and dry mouth. Drink plenty of fluids and let your doctor know if you develop extreme thirst, muscle weakness or a very dry mouth.

Amlodac D Tablet can cause dizziness as one of its side effects. If you feel dizzy, try getting up slowly from a sitting or lying position. If your dizziness is severe or unmanageable, please seek medical advice.

It is advised to consult your doctor before taking Amlodac D Tablet if you have a history of severe kidney or liver diseases, low potassium levels (hypokalaemia), diabetes, gout, abnormal heart rhythms, thyroid disorders and asthma.

It is recommended to consult your doctor since diuretics (water pills) may increase blood sugar levels. Besides this, beta-blockers (blood pressure-lowering agents) can mask hypoglycemia symptoms (low blood sugar).

Even though your blood pressure becomes normal after using Amlodac D Tablet , it may switch back to high ranges if you stop using it. Your doctor may change the dosing schedule based on your blood pressure range.

Drug-Drug Interactions Checker List

  • SILDENAFIL
  • OXYCODONE
  • PREDNISONE
  • CLONAZEPAM
  • ESOMEPRAZOLE
  • INSULIN GLARGINE
  • METFORMIN
  • CHOLECALCIFEROL
  • RISPERIDONE
  • DULOXETINE
  • DIGOXIN
  • AMIODARONE
  • LISINOPRIL
  • CANDESARTAN
  • LITHIUM
  • NAPROXEN
  • AMISULPRIDE
  • IBUPROFEN
  • PIMOZIDE
  • ALPRAZOLAM
  • CLONIDINE
  • BACLOFEN
  • LEVODOPA
  • METOPROLOL
  • CHLORTHALIDONE
  • HYDROCHLOROTHIAZIDE
  • FUROSEMIDE
  • TORSEMIDE
  • RAMIPRIL

Special Advise

  • Monitor your blood pressure regularly and seek medical advice if you notice any drastic fluctuations.
  • Let your doctor know if you are advised for any blood examinations as diuretics like Indapamide can cause changes in the laboratory parameters like low potassium levels in the blood, low sodium in the blood, low blood pressure, increase in uric acid, increase in blood glucose levels in diabetic patients, increase in calcium levels in the blood, and increase in the liver enzyme levels. 
  • Let your anaesthetist or medical staff know that you are taking Amlodac D Tablet since Amlodac D Tablet  can lower blood pressure levels when certain anaesthetic medications are given during any operation or surgery.
  • Athletes should be aware that Indapamide in Amlodac D Tablet gives a positive reaction in doping tests.

Disease/Condition Glossary

Hypertension: When blood pressure is excessively high, it becomes a chronic problem. Blood pressure is determined by how much blood the heart pumps and how much resistance the arteries provide to the flow of blood. Blood pressure rises, and arteries constrict as the heart pumps more blood. If not treated, uncontrolled blood pressure can cause major cardiac conditions, including heart attack and stroke. Kidney failure and brain damage are two more effects of high blood pressure. Headache, bleeding from the nose, nausea, and chest discomfort are a few signs of hypertension.

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