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Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Amlopres L Tablet

Amlopres L Tablet belongs to the class of 'anti-hypertensive drugs', primarily used to treat hypertension (high blood pressure). Hypertension is a medical condition in which the blood exerts high pressure (force exerted by circulating blood) against blood vessels' walls. This condition makes the heart work harder in pumping blood to the whole body. Hypertension can cause severe health complications, including stroke, heart failure, heart attack, and kidney failure.

Amlopres L Tablet is a combination of medicine that consists of Amlodipine (calcium channel blocker) and Lisinopril (angiotensin-converting enzyme inhibitor). Amlodipine belongs to the class of 'calcium channel blockers and is used to treat high blood pressure, Prinzmetal's or variant angina (chest pain), and other conditions caused by coronary artery disease. It relaxes blood vessels so that blood passes through them easily, lowering blood pressure. Amlodipine also improves blood supply to the heart muscle to receive more oxygen and thus preventing chest pain. Lisinopril belongs to the class of 'Angiotensin-Converting Enzyme (ACE) Inhibitors.' It relaxes and widens the blood vessels making it easier for the heart to pump blood throughout the body, lowering blood pressure. Lisinopril also decreases the body’s production of certain substances that raise blood pressure.

Amlopres L Tablet is an orally administered drug in the form of a tablet and capsule. You can take Amlopres L Tablet with food or without food. Swallow it as a whole with a glass of water. Do not chew, bite, or break it. Your doctor will advise you how often you take Amlopres L Tablet based on your medical condition. In some cases, you may experience blurred vision, sweating, confusion, tiredness, stomach upset, flushing (sense of warmth in the face, ears, neck and trunk), dizziness, headache, and swelling of the ankles or feet. Most of these side effects of Amlopres L Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, please contact your doctor.

Do not stop taking Amlopres L Tablet without consulting your doctor since it may worsen your condition and increase the risk of future heart problems. Regular monitoring of blood pressure, electrolyte levels and kidney functioning is advised while taking Amlopres L Tablet . Inform your doctor if you are suffering from kidney, liver or heart diseases. Please tell your doctor if you are taking other medicines or allergic to Amlopres L Tablet . Reducing the amount of table salt (sodium chloride) in your food often relieves the body's swelling. Let your doctor know if you use any prescription and non-prescription medications you are taking, including vitamins, before starting Amlopres L Tablet . If you are pregnant or breastfeeding, please tell your doctor so that the dosage of Amlopres L Tablet can be prescribed accordingly.

Uses of Amlopres L Tablet

Hypertension (high blood pressure)

Directions for Use

Take the tablet with or without food or as directed by your physician. Swallow it with a glass of water. Do not crush, chew, or break it. Try to take it at a fixed time every day. Do not double the dose if missed.

Medicinal Benefits

Amlopres L Tablet treats hypertension (high blood pressure) and consists of Amlodipine (calcium channel blocker) and Lisinopril (angiotensin-converting enzyme inhibitor). Amlodipine is a 'calcium channel blocker' and treats high blood pressure, Prinzmetal's or variant angina (chest pain), and other conditions caused by coronary artery disease. It relaxes blood vessels so that blood passes through them easily, lowering blood pressure. It also treats chest pain by improving the blood supply to the heart muscle to receive more oxygen. Amlodipine also improves a person's tolerance to exercise and keeps the blood pressure at acceptable levels. Lisinopril is an 'Angiotensin-Converting Enzyme (ACE) Inhibitor.' It relaxes and widens the blood vessels making it easier for the heart to pump blood throughout the body, lowering blood pressure.

Storage

Keep Amlopres L Tablet out of sight and reach of children.

Drug Warnings

  • Do not use Amlopres L Tablet if you are allergic to Amlopres L Tablet or its components.
  • Please inform your doctor if you are using any prescription and non-prescription medications, including vitamins, before starting Amlopres L Tablet .
  • Let your doctor know if you have any history of severe heart, kidney or liver diseases, high potassium levels (hyperkalaemia), bone marrow suppression, and aortic stenosis (heart valve problem). 
  • It is essential to inform your doctor if you are a breastfeeding mother before using Amlopres L Tablet since Amlodipine may pass into the breast milk.
  • Lisinopril is not recommended during pregnancy since it harms the unborn baby. Please ask your doctor if you plan to conceive or are pregnant before using Amlopres L Tablet .
  • Amlopres L Tablet can increase the chances of light-headedness so rise slowly if you are sitting/lying and avoid operating any machine or doing any work that needs mental alertness.

Drug-Drug Interactions

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AmlodipineDantrolene
Critical

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
How does the drug interact with Amlopres L Tablet:
Using Amlopres L Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Amlopres L Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
How does the drug interact with Amlopres L Tablet:
Combining Aliskiren with Amlopres L Tablet can increase the potassium levels in the blood.

How to manage the interaction:
Although taking Aliskiren and Amlopres L Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience symptoms including weakness, tiredness, confusion, numbness or tingling, and irregular heartbeats. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Amlopres L Tablet:
Coadministration of Ceritinib together with Amlopres L Tablet can slow heart rate and increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Amlopres L Tablet with Ceritinib, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, or an irregular heartbeat, consult the doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Amlopres L Tablet:
Using Amlopres L Tablet and phenytoin together may drastically lower Amlopres L Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although Amlopres L Tablet with phenytoin can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Amlopres L Tablet:
Using Amlopres L Tablet and rifabutin together may lower Amlopres L Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although there is an interaction between Amlopres L Tablet with rifabutin, but it can be taken if a doctor has advised it. Consult the doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Amlopres L Tablet:
Coadministration of Amlopres L Tablet and rifampicin together may lower Amlopres L Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although there is an interaction between Amlopres L Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Amlopres L Tablet:
Coadministration of Amlopres L Tablet with itraconazole may significantly raise the blood levels and effects of Amlopres L Tablet.

How to manage the interaction:
Amlopres L Tablet and itraconazole may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you develop chest discomfort, trouble breathing, dizziness or fainting, swelling of the hands, ankles, or feet, or any other of these symptoms. Without consulting a doctor, never stop taking any medication.
AmlodipineMitotane
Severe
How does the drug interact with Amlopres L Tablet:
Using Amlopres L Tablet and mitotane together may drastically lower Amlopres L Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Amlopres L Tablet with mitotane can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Amlopres L Tablet:
Co-administration of Amlopres L Tablet can make Sirolimus may increase the risk of angioedema (a condition associated with swelling of the face, eyes, lips, tongue, throat, and occasionally also the hands and feet).

How to manage the interaction:
There may be a possibility of interaction between Amlopres L Tablet and Sirolimus, but it can be taken if prescribed by a doctor. However, consult the doctor if you notice any swelling of the face, eyes, lips, tongue, throat, hands and feet or have trouble breathing or swallowing. Do not stop using any medications without a doctor's advice.
How does the drug interact with Amlopres L Tablet:
Using Amlopres L Tablet and primidone together may lower Amlopres L Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Amlopres L Tablet with primidone can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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AMLODIPINE-5MG+LISINOPRIL-5MGPotassium rich foods
Moderate

Drug-Food Interactions

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AMLODIPINE-5MG+LISINOPRIL-5MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Taking Amlopres L Tablet with potassium-containing salt substitutes or potassium supplements can cause high levels of potassium in the blood. Avoid taking potassium-containing salt substitutes or potassium supplements while being treated with Amlopres L Tablet.

Diet & Lifestyle Advise

  • Keep your weight under control with body mass index (BMI) between 19.5 and 24.9.
  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help lower your raised blood pressure by about 5 mm of Hg.
  • Limit sodium chloride intake (table salt) in your daily diet to 2300 mg daily or less than 1500 mg is ideal for most adults.
  • If you are taking alcohol, use only one serving for women and two servings for men.
  • Quit smoking to lower the risk of heart disease.
  • Avoid chronic stress, as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress.
  • Monitor your blood pressure daily, and if you notice any fluctuations frequently, please contact your doctor immediately.
  • Try including heart-healthy omega-3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oils like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Side Effects of Amlopres L Tablet

  • Confusion
  • Sweating
  • Tiredness
  • Dizziness
  • Headache
  • Blurred vision
  • Stomach upset
  • Swelling of the ankles or feet
  • Flushing (sense of warmth in the face, ears, neck and trunk)

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Amlopres L Tablet treats hypertension (high blood pressure) and consists of Amlodipine (calcium channel blocker) and Lisinopril (angiotensin-converting enzyme inhibitor). Amlodipine is a 'calcium channel blocker' and treats high blood pressure, Prinzmetal's or variant angina (chest pain), and other conditions caused by coronary artery disease. It relaxes blood vessels so that blood passes through them easily, lowering blood pressure.

Amlopres L Tablet is recommended to use in dose and duration as advised by the doctor. Do not stop taking Amlopres L Tablet on your own, as it may lead to a sudden rise in blood pressure and increases the risk of heart attack and stroke.

Amlopres L Tablet may increase blood potassium levels in people with diabetes, poor kidney function, and patients using potassium-sparing diuretics or taking potassium supplements. Please consult your doctor before taking Amlopres L Tablet if you have diabetes.

Amlodipine in Amlopres L Tablet can cause ankle swelling upon long-term use. Please try to keep your feet in an elevated position when sitting for long hours. If the problem persists, please consult your doctor and do as advised.

Even though your blood pressure becomes normal after using Amlopres L Tablet , it may switch back to high ranges if you stop using it. Your doctor may change the dosing schedule based on your blood pressure range.

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and return to your regular dosing schedule.

Drug-Drug Interactions Checker List

  • SIMVASTATIN
  • PREDNISOLONE
  • BENDROFLUMETHIAZIDE
  • NAPROXEN
  • INSULIN GLARGINE
  • PREGABALIN
  • SITAGLIPTIN
  • ALLOPURINOL
  • SILDENAFIL
  • METOPROLOL
  • RAMIPRIL
  • FUROSEMIDE
  • IBUPROFEN
  • METFORMIN

Special Advise

  • Monitor your blood pressure regularly and seek medical advice if you notice any drastic fluctuations.
  • Amlopres L Tablet may affect patients with hepatic impairment, and hence it is used cautiously, and Liver function monitoring and Liver Function Tests are advised to monitor the liver enzyme changes.
  • Your doctor may advise you to get a regular kidney function test and blood examinations for potassium levels and other electrolytes while using Amlopres L Tablet to rule out any renal impairment.

Disease/Condition Glossary

Hypertension: When your blood pressure is too high, you have a chronic condition. The amount of blood pumped by the heart and the amount of resistance exerted by the arteries against the blood flow is called blood pressure. When the heart pumps more blood, the arteries narrow, and the blood pressure rises. Uncontrolled blood pressure can lead to serious heart problems such as stroke and heart attack. High blood pressure can also damage the brain (stroke) and lead to kidney failure. The systolic and diastolic pressures of blood are measured. The contraction and relaxation of the heart are represented by systolic blood pressure. Diastolic pressure is exerted in the blood vessels when the heart is at rest and not beating. The ideal blood pressure range is 90/60 mmHg to 120/80 mmHg. When systolic blood pressure exceeds 140mmHg, and diastolic pressure exceeds 90mmHg, hypertension is diagnosed. Hypertension symptoms include headaches, nosebleeds, vomiting, and chest pain.

Have a query?

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Alcohol

Caution

Alcohol may lower your blood pressure. Limit or avoid consuming alcohol while on treatment with Amlopres L Tablet is advisable.

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Pregnancy

Unsafe

Lisinopril in Amlopres L Tablet is a pregnancy D category drug and is not recommended during pregnancy since it causes harmful effects on the developing foetus. However, it is advised to seek medical advice before using Amlopres L Tablet if you plan to conceive or pregnant.

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Breast Feeding

Caution

There are limited studies on how Amlopres L Tablet affects breastfed infants. However, Amlodipine in Amlopres L Tablet passes into the breast milk during breastfeeding. Please consult your doctor before using Amlopres L Tablet if you are a lactating mother.

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Driving

Caution

Amlopres L Tablet may cause side effects from lowering blood pressure, such as dizziness or tiredness. If you feel dizzy or tired when taking this medicine, do not drive or use any tools or machines.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before using Amlopres L Tablet . Your doctor may adjust the dose based on your condition.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before using Amlopres L Tablet . Amlopres L Tablet is primarily eliminated by the kidney and can be accumulated in patients with renal impairment. Your doctor may adjust the dose based on your condition.

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Children

Unsafe

Amlopres L Tablet is not recommended for children as efficacy and safety have not been established.

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