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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Not for online sale
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer :

Centaur Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Amnurite P Tablet

Amnurite P Tablet is a combination medicine indicated for the management of neuropathic pain. Neuropathic pain is a chronic progressive nerve disease which causes nerve pain due to nerve damage or a malfunctioning nervous system. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling or burning sensation.

Amnurite P Tablet is a combination of two drugs: Pregabalin (anti-convulsant), and Amitriptyline (antidepressant). Pregabalin works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain. Amitriptyline increases the level of serotonin and noradrenaline, thereby decreasing the movement of pain receptors. Together, Amnurite P Tablet helps to treat neuropathic pain. 

You are advised to take Amnurite P Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as weight gain, dry mouth, blurred vision, dizziness, tiredness, nausea, vomiting, diarrhoea, and constipation. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Amnurite P Tablet may cause drowsiness and dizziness, so drive only if you are alert. Amnurite P Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Amnurite P Tablet as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Amnurite P Tablet

Neuropathic pain

Directions for Use

Take Amnurite P Tablet with or without food. Swallow Amnurite P Tablet as a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Amnurite P Tablet is a combination of two drugs: Pregabalin (anti-convulsant), and Amitriptyline (antidepressant). Pregabalin works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain. Amitriptyline increases the level of serotonin and noradrenaline, thereby decreasing the movement of pain receptors. Together, Amnurite P Tablet helps to treat neuropathic pain. 

Storage

Keep Amnurite P Tablet out of reach and sight of children.
Side effects of Amnurite P Tablet
  • Wear compression garments like stockings, sleeves, or gloves to apply pressure and help stop fluid from building up, especially after the swelling goes down.
  • Move around and do exercises to help the fluid circulate, especially in swollen limbs. Ask your doctor for specific exercises.
  • Raise the swollen area above your heart level several times a day, even while sleeping, to help reduce swelling.
  • Gently massage the swollen area with firm but not painful pressure.
  • Keep the swollen area clean and moisturized to prevent injury and infection.
  • Reduce salt intake to help prevent fluid from building up and worsening the swelling, as advised by a doctor.
  • If the swelling does not get better after a few days of home treatment or worsens, consult your doctor right away.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Include fruits, vegetables, and whole grains in your diet.
  • Exercise regularly.
  • Quit smoking as it may increase the risk of neuropathy.
  • Getting massage therapy and acupuncture might help with pain.
  • Avoid massaging the bruise, as this might worsen the damage to the injured tissue.
  • Resting the affected area helps prevent more injury and aids healing.
  • Place a cloth-wrapped ice pack or cold compress on the affected area for 10 to 15 minutes.
  • If the bruise is extensive, severe, or accompanied by other symptoms like warmth, redness, or swelling, get medical help.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
  • Limit your intake of carbonated drinks, alcohol and caffeine as these substances can irritate your bladder.
  • Do Kegel exercises to strengthen pelvic floor muscles and improve bladder control.
  • Use absorbent pads or underwear to manage accidental urination.
  • If incontinence continues or worsens, see a doctor to check for underlying issues.
  • Uncoordinated muscle movements need immediate medical attention.
  • Observe your movements and try to understand and control the particular movement.
  • Regularly do strengthening exercises to improve blood flow throughout the body and avoid involuntary movements.
  • Implement massage techniques to enhance blood flow to organs.
  • Take a balanced diet and quit smoking.
  • Practice yoga and meditation to improve thought processes and reduce uncontrolled and involuntary movements.

Drug Warnings

Do not take Amnurite P Tablet if you are allergic to any of its contents; if you have taken MAO inhibitors in the last 14days. Inform your doctor before taking Amnurite P Tablet if you have/had heart problems, bipolar syndrome, severe liver disease or porphyria. Consult your doctor if you are pregnant or breastfeeding. Amnurite P Tablet may cause drowsiness and dizziness, so drive only if you are alert. Amnurite P Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Amnurite P Tablet as it could lead to increased drowsiness and sleepiness.

Drug-Drug Interactions

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AmitriptylineHalofantrine
Critical

Drug-Drug Interactions

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AmitriptylineHalofantrine
Critical
How does the drug interact with Amnurite P Tablet:
Combining Amnurite P Tablet and Halofantrine may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Amnurite P Tablet with Halofantrine may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Amnurite P Tablet:
Combining Amnurite P Tablet and Pimozide may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Amnurite P Tablet with Pimozide may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Amnurite P Tablet:
Combining Furazolidone with Amnurite P Tablet can increase the risk of serotonin syndrome(increased serotonin hormone).

How to manage the interaction:
Although using Furazolidone and Amnurite P Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken Amnurite P Tablet. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Amnurite P Tablet:
Using Amnurite P Tablet together with Procarbazine can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is especially a mood stabilizer).

How to manage the interaction:
Although using Procarbazine and Amnurite P Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken Amnurite P Tablet. Do not discontinue any medications without consulting a doctor.
AmitriptylineGrepafloxacin
Critical
How does the drug interact with Amnurite P Tablet:
Combining Amnurite P Tablet and Grepafloxacin may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Amnurite P Tablet with Grepafloxacin may result in an interaction, it can be used if a doctor recommends it. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor. Note: Grepafloxacin is no longer available in the market. Grepafloxacin should not be combined with any other medications.
AmitriptylineMesoridazine
Critical
How does the drug interact with Amnurite P Tablet:
Coadministration of Amnurite P Tablet and Mesoridazine may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Amnurite P Tablet with Mesoridazine may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Amnurite P Tablet:
Coadministration of Amnurite P Tablet and Cisapride may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Amnurite P Tablet with Cisapride may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Amnurite P Tablet:
Combining Amnurite P Tablet and Dronedarone may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Amnurite P Tablet with Dronedarone may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Amnurite P Tablet:
Amnurite P Tablet and Thioridazine can enhance each other's effects when used together.

How to manage the interaction:
Although using Amnurite P Tablet and Thioridazine together can cause an interaction, they can be used if prescribed by a doctor. If you have extreme sleepiness, confusion, anxiety, vomiting, vision problems, feeling hot or cold, sweating, muscle stiffness, fainting, fits, or coma, seek medical help. Do not discontinue any medications without consulting a doctor.
AmitriptylineIsocarboxazid
Critical
How does the drug interact with Amnurite P Tablet:
Combining Isocarboxazid with Amnurite P Tablet can increase the risk of serotonin syndrome (increase serotonin hormone).

How to manage the interaction:
Although using Isocarboxazid and Amnurite P Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken Amnurite P Tablet. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet.
  • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.
  • Exercising regularly helps in improving overall health and combating pain.
  • Rest well, and get plenty of sleep.
  • Try taking a warm bath, as it can be soothing.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.
  • Acupuncture can be helpful by stimulating pressure points.
  • Using essential oils for massages can help increase circulation.

Side Effects of Amnurite P Tablet

  • Weight gain
  • Dry mouth
  • Blurred vision
  • Dizziness
  • Tiredness
  • Nausea
  • Vomiting
  • Diarrhoea
  • Constipation

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Amnurite P Tablet contains Pregabalin and Amitriptyline. Pregabalin works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain. Amitriptyline increases the level of serotonin and noradrenaline, thereby decreasing the movement of pain receptors. Together, Amnurite P Tablet helps to treat neuropathic pain.

Amnurite P Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by regular exercise and following a proper diet.

Dry mouth could be a side-effect of Amnurite P Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

To treat your condition effectually, continue taking Amnurite P Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Amnurite P Tablet ; your doctor will reduce the dose gradually.

Amnurite P Tablet is used to treat neuropathic pain due to diabetic neuropathy. Diabetic neuropathy is a condition in which nerve damage occurs due to high blood glucose levels. It mostly damages the nerves in legs and feet.

Amnurite P Tablet may cause sexual disturbances such as decreased sex drive and problems with erection. Consult your doctor if you have any concerns regarding this.

Drug-Drug Interactions Checker List

  • DULOXETINE
  • SERTRALINE
  • ESCITALOPRAM
  • FENTANYL
  • HYDROCODONE
  • ACETAMINOPHEN
  • MORPHINE
  • OXYCODONE
  • TOPIRAMATE
  • ALPRAZOLAM
  • ZOLPIDEM
  • DIPHENHYDRAMINE
  • CETIRIZINE
  • CYCLOBENZAPRINE
  • LEVOTHYROXINE

Disease/Condition Glossary

Neuropathic pain: Neuropathic pain is caused due to damage to sensory nerves. It is caused by chronic progressive nerve disease or due to infection or injury. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling or burning sensation. A feeling of numbness and loss of sensations is also common with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain is not triggered by an injury; the body unpromptedly sends the pain signals. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping, and evoked pain (pain caused by events usually not painful).

Have a query?

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Amnurite P Tablet as it may increase drowsiness and sleepiness.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Amnurite P Tablet ; your doctor will decide whether Amnurite P Tablet can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Amnurite P Tablet may cause drowsiness, sleepiness and blurred vision. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Amnurite P Tablet should not be given to children as the safety and efficacy have not been established.

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