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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Consume Type :

ORAL

Return Policy :

Not Returnable

About Jesgab-T Tablet

Jesgab-T Tablet is a combination medicine indicated for the management of neuropathic pain. Neuropathic pain is a chronic progressive nerve disease which causes nerve pain due to nerve damage or a malfunctioning nervous system. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling or burning sensation.

Jesgab-T Tablet is a combination of two drugs: Pregabalin (anti-convulsant), and Amitriptyline (antidepressant). Pregabalin works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain. Amitriptyline increases the level of serotonin and noradrenaline, thereby decreasing the movement of pain receptors. Together, Jesgab-T Tablet helps to treat neuropathic pain. 

You are advised to take Jesgab-T Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as weight gain, dry mouth, blurred vision, dizziness, tiredness, nausea, vomiting, diarrhoea, and constipation. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Jesgab-T Tablet may cause drowsiness and dizziness, so drive only if you are alert. Jesgab-T Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Jesgab-T Tablet as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Jesgab-T Tablet

Neuropathic pain

Directions for Use

Take Jesgab-T Tablet with or without food. Swallow Jesgab-T Tablet as a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Jesgab-T Tablet is a combination of two drugs: Pregabalin (anti-convulsant), and Amitriptyline (antidepressant). Pregabalin works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain. Amitriptyline increases the level of serotonin and noradrenaline, thereby decreasing the movement of pain receptors. Together, Jesgab-T Tablet helps to treat neuropathic pain. 

Storage

Keep Jesgab-T Tablet out of reach and sight of children.

Drug Warnings

Do not take Jesgab-T Tablet if you are allergic to any of its contents; if you have taken MAO inhibitors in the last 14days. Inform your doctor before taking Jesgab-T Tablet if you have/had heart problems, bipolar syndrome, severe liver disease or porphyria. Consult your doctor if you are pregnant or breastfeeding. Jesgab-T Tablet may cause drowsiness and dizziness, so drive only if you are alert. Jesgab-T Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Jesgab-T Tablet as it could lead to increased drowsiness and sleepiness.

Drug-Drug Interactions

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AmitriptylineMesoridazine
Critical

Drug-Drug Interactions

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AmitriptylineMesoridazine
Critical
How does the drug interact with Jesgab-T Tablet:
Coadministration of Jesgab-T Tablet and Mesoridazine may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Jesgab-T Tablet with Mesoridazine may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Jesgab-T Tablet:
Using Jesgab-T Tablet together with Rasagiline can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is especially a mood stabilizer).

How to manage the interaction:
Although using Rasagiline and Jesgab-T Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Inform a doctor if you have recently taken Jesgab-T Tablet. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Jesgab-T Tablet:
Jesgab-T Tablet and Thioridazine can enhance each other's effects when used together.

How to manage the interaction:
Although using Jesgab-T Tablet and Thioridazine together can cause an interaction, they can be used if prescribed by a doctor. If you have extreme sleepiness, confusion, anxiety, vomiting, vision problems, feeling hot or cold, sweating, muscle stiffness, fainting, fits, or coma, seek medical help. Do not discontinue any medications without consulting a doctor.
AmitriptylineHalofantrine
Critical
How does the drug interact with Jesgab-T Tablet:
Combining Jesgab-T Tablet and Halofantrine may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Jesgab-T Tablet with Halofantrine may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
AmitriptylineSaquinavir
Critical
How does the drug interact with Jesgab-T Tablet:
Combining Jesgab-T Tablet and Saquinavir may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Jesgab-T Tablet with Saquinavir may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
Critical
How does the drug interact with Jesgab-T Tablet:
Combining Jesgab-T Tablet and Bepridil may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Jesgab-T Tablet with Bepridil may result in an interaction, it can be used if a doctor recommends it. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Jesgab-T Tablet:
Using Jesgab-T Tablet together with Procarbazine can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is especially a mood stabilizer).

How to manage the interaction:
Although using Procarbazine and Jesgab-T Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken Jesgab-T Tablet. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Jesgab-T Tablet:
Combining Furazolidone with Jesgab-T Tablet can increase the risk of serotonin syndrome(increased serotonin hormone).

How to manage the interaction:
Although using Furazolidone and Jesgab-T Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken Jesgab-T Tablet. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Jesgab-T Tablet:
Combining Jesgab-T Tablet and Pimozide may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Jesgab-T Tablet with Pimozide may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Jesgab-T Tablet:
Combining Methylene blue with Jesgab-T Tablet can increase the risk of serotonin syndrome (increased serotonin hormone).

How to manage the interaction:
Although using Methylene blue and Jesgab-T Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken Jesgab-T Tablet. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet.
  • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.
  • Exercising regularly helps in improving overall health and combating pain.
  • Rest well, and get plenty of sleep.
  • Try taking a warm bath, as it can be soothing.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.
  • Acupuncture can be helpful by stimulating pressure points.
  • Using essential oils for massages can help increase circulation.

Side Effects of Jesgab-T Tablet

  • Weight gain
  • Dry mouth
  • Blurred vision
  • Dizziness
  • Tiredness
  • Nausea
  • Vomiting
  • Diarrhoea
  • Constipation

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Jesgab-T Tablet contains Pregabalin and Amitriptyline. Pregabalin works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain. Amitriptyline increases the level of serotonin and noradrenaline, thereby decreasing the movement of pain receptors. Together, Jesgab-T Tablet helps to treat neuropathic pain.

Jesgab-T Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by regular exercise and following a proper diet.

Dry mouth could be a side-effect of Jesgab-T Tablet. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

To treat your condition effectually, continue taking Jesgab-T Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Jesgab-T Tablet; your doctor will reduce the dose gradually.

Jesgab-T Tablet is used to treat neuropathic pain due to diabetic neuropathy. Diabetic neuropathy is a condition in which nerve damage occurs due to high blood glucose levels. It mostly damages the nerves in legs and feet.

Jesgab-T Tablet may cause sexual disturbances such as decreased sex drive and problems with erection. Consult your doctor if you have any concerns regarding this.

Drug-Drug Interactions Checker List

  • DULOXETINE
  • SERTRALINE
  • ESCITALOPRAM
  • FENTANYL
  • HYDROCODONE
  • ACETAMINOPHEN
  • MORPHINE
  • OXYCODONE
  • TOPIRAMATE
  • ALPRAZOLAM
  • ZOLPIDEM
  • DIPHENHYDRAMINE
  • CETIRIZINE
  • CYCLOBENZAPRINE
  • LEVOTHYROXINE

Disease/Condition Glossary

Neuropathic pain: Neuropathic pain is caused due to damage to sensory nerves. It is caused by chronic progressive nerve disease or due to infection or injury. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling or burning sensation. A feeling of numbness and loss of sensations is also common with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain is not triggered by an injury; the body unpromptedly sends the pain signals. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping, and evoked pain (pain caused by events usually not painful).

Have a query?

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Jesgab-T Tablet as it may increase drowsiness and sleepiness.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Jesgab-T Tablet; your doctor will decide whether Jesgab-T Tablet can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Jesgab-T Tablet may cause drowsiness, sleepiness and blurred vision. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Jesgab-T Tablet should not be given to children as the safety and efficacy have not been established.

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