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Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
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Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Ampholip 50 Injection 10 ml

Ampholip 50 Injection 10 ml belongs to a class of medication called 'antifungal' used to treat severe fungal infections like leishmaniasis. A fungal infection is a disease in which fungi attack the tissue and cause infection. Fungi are commonly present in nature but do not cause infections normally. However, if the person has a weak immune system, certain types of fungi may infect them. 

Ampholip 50 Injection 10 ml contains Amphotericin B, which kills fungi by destroying the fungal outer cell membrane. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents.

Ampholip 50 Injection 10 ml is given by a doctor or nurse. In some cases, you may experience fever, chills, irregular heartbeat, high or low blood pressure, breathing problems, nausea, vomiting, headache, shaking, muscle cramps or pain. Most of these side effects of Ampholip 50 Injection 10 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Ampholip 50 Injection 10 ml or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Ampholip 50 Injection 10 ml. Ampholip 50 Injection 10 ml is not recommended for children below one month as the safety and effectiveness were not established. Avoid driving after taking Ampholip 50 Injection 10 ml as it may affect your ability to drive. If you experience severe adverse effects such as chest pain or difficulty in breathing, or encephalopathy (a brain disease which may cause you to behave strangely, be confused or feel drowsy), seek immediate medical help.

Uses of Ampholip 50 Injection 10 ml

Severe fungal infections

Directions for Use

Ampholip 50 Injection 10 ml will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Ampholip 50 Injection 10 ml contains Amphotericin B, an antifungal used to treat severe fungal infections. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Ampholip 50 Injection 10 ml damages fungal cell membranes and kills fungi. Ampholip 50 Injection 10 ml is used to treat infections such as blood infection with candida, cryptococcus, fusarium, zygomycetes, aspergillus, coccidiodes or blastomycetes, or cryptococcal meningitis (inflammation of the brain).

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ampholip 50 Injection 10 ml

  • Fever
  • Chills
  • Irregular heartbeat
  • High or low blood pressure
  • Breathing problems
  • Nausea
  • Vomiting
  • Headache
  • Shaking
  • Muscle cramps or pain

Drug Warnings

If you are allergic to Amphotericin B or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Ampholip 50 Injection 10 ml. Ampholip 50 Injection 10 ml is not recommended for children below one month as the safety and effectiveness were not established. Avoid driving after taking Ampholip 50 Injection 10 ml as it may affect your ability to drive. If you experience severe adverse effects such as chest pain, difficulty breathing, or encephalopathy (a brain disease that may cause you to behave strangely, be confused or feel drowsy), seek immediate medical help. If you have diabetes, electrolyte imbalance (low magnesium or potassium levels in the blood), kidney, liver or heart problems, inform your doctor before taking Ampholip 50 Injection 10 ml.

Drug-Drug Interactions

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Amphotericin bStreptozocin
Critical
Amphotericin bIopamidol
Severe

Drug-Drug Interactions

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Amphotericin bStreptozocin
Critical
How does the drug interact with Ampholip 50 Injection 10 ml:
Taking Ampholip 50 Injection 10 ml and streptozocin together can enhance kidney injury and can cause damage to the ear.

How to manage the interaction:
Taking Streptozocin with Ampholip 50 Injection 10 ml is not recommended as it can result in an interaction, it can be taken if a doctor has advised it.
Amphotericin bIopamidol
Severe
How does the drug interact with Ampholip 50 Injection 10 ml:
Coadministration of Ampholip 50 Injection 10 ml and Iopamidol may increase the risk of kidney problem.

How to manage the interaction:
Taking Ampholip 50 Injection 10 ml with Iopamidol together can result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on how much you pee. If you notice any changes like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm let the doctor know right away. Do not discontinue any medications without consulting a doctor.
Amphotericin bMetrizamide
Severe
How does the drug interact with Ampholip 50 Injection 10 ml:
Coadministration of Ampholip 50 Injection 10 ml and Metrizamide may increase the risk of kidney damage.

How to manage the interaction:
Co-administration of Ampholip 50 Injection 10 ml with Metrizamide can result in an interaction, but it can be taken if a doctor has advised it. If you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, let the doctor know. Do not stop using any medications without talking to a doctor.
Amphotericin bDroperidol
Severe
How does the drug interact with Ampholip 50 Injection 10 ml:
Using droperidol together with Ampholip 50 Injection 10 ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although taking Ampholip 50 Injection 10 ml and Droperidol together can cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these symptoms - an irregular heart rhythm, a heart condition, a condition called congenital long qt syndrome, problems with your heart's conduction, severe or long-lasting diarrhea, vomiting, complications, sudden dizziness, feeling lightheaded, fainting, difficulty breathing, heart palpitations, feeling weak, feeling sleepy, feeling confused, muscle pain, feeling nauseous or vomiting - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
Amphotericin bIodamide
Severe
How does the drug interact with Ampholip 50 Injection 10 ml:
Coadministration of Ampholip 50 Injection 10 ml and Iodamide may increase the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between Ampholip 50 Injection 10 ml and Iodamide, you can take these medicines together if prescribed by a doctor. It's important to keep an eye on how much you pee. If you notice any changes, let the doctor know. If you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
Amphotericin bIoversol
Severe
How does the drug interact with Ampholip 50 Injection 10 ml:
Coadministration of Ampholip 50 Injection 10 ml and Ioversol may increase the risk of kidney damage.

How to manage the interaction:
There may be a possibility of interaction between Ampholip 50 Injection 10 ml and Ioversol, but it can be taken if prescribed by a doctor. If you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without talking to a doctor.
Amphotericin bFoscarnet
Severe
How does the drug interact with Ampholip 50 Injection 10 ml:
Using foscarnet together with Ampholip 50 Injection 10 ml can cause serious side effects to the kidneys. Using these drugs together can also increase the risks of seizures (fits) and an irregular heart rhythm.

How to manage the interaction:
There may be a possibility of interaction between Ampholip 50 Injection 10 ml and Foscarnet, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away: seizures, an irregular heart rhythm, feeling sick, swelling, sudden weight gain or loss, severe pain in your upper stomach that spreads, strong heartbeats, feeling dizzy, or chest pain. Do not discontinue any medications without consulting a doctor.
Amphotericin bIotalamic acid
Severe
How does the drug interact with Ampholip 50 Injection 10 ml:
Coadministration of Ampholip 50 Injection 10 ml and Iotalamic acid may decrease the excretion rate of Iothalamic acid which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Ampholip 50 Injection 10 ml and Iotalamic acid, you can take these medicines together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
Amphotericin bIodixanol
Severe
How does the drug interact with Ampholip 50 Injection 10 ml:
Coadministration of Ampholip 50 Injection 10 ml and Iodixanol can cause higher levels of Iodixanol in the blood by reducing its excretion rate.

How to manage the interaction:
There may be a possibility of interaction between Ampholip 50 Injection 10 ml and Iodixanol, but it can be taken if prescribed by a doctor. It's important to keep an eye on how much you pee. If you notice any changes, like peeing more or less than usual, it's a good idea to let the doctor know right away. These changes could be a sign of different health issues, like problems with your kidneys, diabetes, or dehydration. Other symptoms to watch out for include feeling sick, throwing up, not wanting to eat, gaining or losing weight suddenly, or having trouble breathing. Do not stop using any medications without talking to a doctor.
Amphotericin bDronedarone
Severe
How does the drug interact with Ampholip 50 Injection 10 ml:
Dronedarone used with Ampholip 50 Injection 10 ml may raise the chance of a significantly abnormal heart rhythm, although it is a rare side effect.

How to manage the interaction:
Although there is a possible interaction between Ampholip 50 Injection 10 ml and Dronedarone, you can take these medicines together if prescribed by a doctor. You should also notify a doctor if you suffer any of the following symptoms: weakness, weariness, sleepiness, disorientation, muscular pain, cramps, dizziness, nausea, or vomiting. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Wash your hands regularly and keep your hands clean to prevent the spread of germs.
  • Avoid dusty activities and digging in the soil.
  • Wear shoes, a long-sleeved t-shirt and long pants while doing outdoor activities such as yard work, gardening or visiting wooded areas to protect from fungus commonly present in the environment.
  • Maintain a diet that is low in sugar, refined carbohydrates, mould-containing foods and yeast.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ZIDOVUDINE
  • CICLOSPORIN
  • FLUCYTOSINE
  • FUROSEMIDE
  • METHOTREXATE

Special Advise

  • Regular blood tests are recommended while taking Ampholip 50 Injection 10 ml to monitor blood, liver or kidney functioning and potassium levels.

Disease/Condition Glossary

Fungal infection is a disease in which fungi attack the tissue and cause infection. Fungi are commonly present in nature but do not cause infections normally. However, if the person has a weak immune system, certain types of fungi may infect them. Cryptococcal meningitis is a fungal infection of tissues covering the spinal cord (meninges) and brain. The symptoms include headache, hallucinations, fever, stiff neck, sensitivity to light, nausea and vomiting. Fungal infections in the lungs may be more serious and life-threatening and often cause symptoms similar to tuberculosis or bacterial pneumonia.

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