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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Hari Kumar , MBBS
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer

Intas Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Amtas PRP Tablet 10's

Amtas PRP Tablet 10's belongs to the group of anti-hypertensive medicines used to treat high blood pressure (hypertension). Additionally, it is also used to treat stable coronary artery disease. High blood pressure is a condition in which the blood exerts increased pressure on the walls of blood vessels. Stable coronary artery disease is a condition in which the blood supply to the heart is blocked or reduced.
 
Amtas PRP Tablet 10's is a combination of two drugs, namely: Amlodipine and Perindopril erbumine. Amlodipine relaxes the blood vessels, thereby improves blood flow. Perindopril erbumine widens the blood vessels, making it easier for the heart to pump blood through them. Together, Amtas PRP Tablet 10's helps lower the blood pressure, thereby reduces the chances of heart problems such as heart attack and stroke.  
 
You are advised to take Amtas PRP Tablet 10's for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as oedema, headache, dizziness, nausea, and abdominal pain. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.
 
Amtas PRP Tablet 10's is not recommended during early pregnancy and should not be taken when more than 3months pregnant as it may cause serious harm to the baby. Amtas PRP Tablet 10's is not recommended for breastfeeding mothers and children. Amtas PRP Tablet 10's may cause dizziness, so drive with caution. Avoid consuming alcohol as it might cause increased dizziness. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects.

Uses of Amtas PRP Tablet 10's

Hypertension (high blood pressure), stable coronary artery disease

Directions for Use

Take Amtas PRP Tablet 10's before a meal. Swallow Amtas PRP Tablet 10's as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Amtas PRP Tablet 10's is a combination of two drugs, namely: Amlodipine and Perindopril erbumine. Amtas PRP Tablet 10's belongs to the group of anti-hypertensive medicines used to treat high blood pressure (hypertension) and/or stable coronary artery disease. Amlodipine is a calcium channel blocker that relaxes the blood vessels, thereby improving blood flow. Perindopril erbumine is an angiotensin-converting enzyme inhibitor that widens the blood vessels; this makes it easier for the heart to pump blood through them. Together, Amtas PRP Tablet 10's helps treat hypertension, thereby reducing the chances of heart problems such as heart attack and stroke.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Amtas PRP Tablet 10's

  • Oedema
  • Headache
  • Dizziness
  • Flushing
  • Light-headedness due to low blood pressure
  • Tiredness
  • Weakness
  • Nausea
  • Vomiting

Drug Warnings

Do not take Amtas PRP Tablet 10's if you are allergic to any of its contents; if you have angioedema, severe water retention, low blood pressure, or low blood potassium. Inform your doctor if you have diabetes, heart problems, gout, parathyroid gland problems, heart failure, collagen disease, atherosclerosis (hardening of arteries), excess acid in the blood, liver/kidney problems, if you are on a low-salt diet, if you are taking lithium/potassium-sparing diuretics, or if you are taking any other blood pressure-lowering medicines. Amtas PRP Tablet 10's is not recommended during early pregnancy and should not be taken when more than 3 months pregnant as it may cause serious harm to the baby. Amtas PRP Tablet 10's is not recommended for breastfeeding mothers and children. Amtas PRP Tablet 10's may cause dizziness, so drive with caution. Keep your doctor informed about your health condition and medications to rule out any interactions.

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
PerindoprilAliskiren
Critical

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
How does the drug interact with Amtas PRP Tablet:
Using Amtas PRP Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Amtas PRP Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
PerindoprilAliskiren
Critical
How does the drug interact with Amtas PRP Tablet:
Combining Aliskiren with Amtas PRP Tablet can increase the risk of low blood pressure, high potassium levels, and kidney damage.

How to manage the interaction:
Taking Amtas PRP Tablet with Aliskiren is not recommended, but can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
AmlodipineTizanidine
Severe
How does the drug interact with Amtas PRP Tablet:
Co-administration of Tizanidine and Amtas PRP Tablet can increase the risk or severity of developing side effects like low blood pressure.

How to manage the interaction:
Although co-administration of Amtas PRP Tablet with tizanidine can result in an interaction, it can be taken when a doctor has advised it. However, if you experience headache, dizziness, palpitations, or irregular heart rate while taking these drugs, contact the doctor immediately. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not discontinue any medications without consulting the doctor.
AmlodipineDolasetron
Severe
How does the drug interact with Amtas PRP Tablet:
Using dolasetron together with Amtas PRP Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
There may be a possibility of interaction between Amtas PRP Tablet and Dolasetron, but it can be taken if prescribed by a doctor. If you have any of these symptoms, like feeling dizzy, lightheaded, or your heart beating irregularly, it's important to call a doctor right away. Do not stop using any medications without a doctor's advice.
AmlodipineRifampicin
Severe
How does the drug interact with Amtas PRP Tablet:
Coadministration of Amtas PRP Tablet and rifampicin together may lower Amtas PRP Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although there is an interaction between Amtas PRP Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
AmlodipineItraconazole
Severe
How does the drug interact with Amtas PRP Tablet:
Coadministration of Amtas PRP Tablet with itraconazole may significantly raise the blood levels and effects of Amtas PRP Tablet.

How to manage the interaction:
Amtas PRP Tablet and itraconazole may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you develop chest discomfort, trouble breathing, dizziness or fainting, swelling of the hands, ankles, or feet, or any other of these symptoms. Without consulting a doctor, never stop taking any medication.
AmlodipinePhenytoin
Severe
How does the drug interact with Amtas PRP Tablet:
Using Amtas PRP Tablet and phenytoin together may drastically lower Amtas PRP Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although Amtas PRP Tablet with phenytoin can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineSirolimus
Severe
How does the drug interact with Amtas PRP Tablet:
Co-administration of Amtas PRP Tablet can make Sirolimus may increase the risk of angioedema (a condition associated with swelling of the face, eyes, lips, tongue, throat, and occasionally also the hands and feet).

How to manage the interaction:
There may be a possibility of interaction between Amtas PRP Tablet and Sirolimus, but it can be taken if prescribed by a doctor. However, consult the doctor if you notice any swelling of the face, eyes, lips, tongue, throat, hands and feet or have trouble breathing or swallowing. Do not stop using any medications without a doctor's advice.
AmlodipineIdelalisib
Severe
How does the drug interact with Amtas PRP Tablet:
Coadministration of Amtas PRP Tablet and Idelalisib may raise Amtas PRP Tablet levels in the blood this may lead to serious side effects (irregular heart rhythm, fluid retention, swelling, heart failure, and abnormally low blood pressure).

How to manage the interaction:
Although taking Amtas PRP Tablet with idelalisib can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness or fainting, sudden, unexplained weight gain, swelling of the hands, ankles, or feet, chest discomfort, or trouble breathing while taking these drugs, consult the doctor. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not stop using any medications without a doctor's advice.
AmlodipineSimvastatin
Severe
How does the drug interact with Amtas PRP Tablet:
Taking simvastatin with Amtas PRP Tablet may result in considerably higher blood levels of simvastatin and may increase the risk of side effects (liver damage and rhabdomyolysis - an uncommon but serious illness characterized by the breakdown of skeletal muscle tissue).

How to manage the interaction:
Although taking Amtas PRP Tablet with simvastatin can result in an interaction, it can be taken if a doctor has advised it. If you have unexplained muscular pain, soreness, or weakness while using simvastatin, especially if these symptoms are accompanied by fever or dark-colored urine, consult the doctor immediately. However, if you develop a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes, consult the doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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AMLODIPINE-5MG+PERINDOPRIL ERBUMINE-4MGPotassium rich foods
Moderate

Drug-Food Interactions

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AMLODIPINE-5MG+PERINDOPRIL ERBUMINE-4MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Taking Amtas PRP Tablet with potassium-containing salt substitutes or potassium supplements can cause high levels of potassium in the blood. Avoid taking potassium-containing salt substitutes or potassium supplements while being treated with Amtas PRP Tablet.

Diet & Lifestyle Advise

  • You are advised to consume low salt and low-fat diet. 
  • Regular exercise is also recommended.
  • Eat a diet rich in whole grains, vegetables, and fruits.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight with proper diet and exercise.
  • Practice meditation or yoga as it helps in managing stress.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • LITHIUM
  • DANTROLENE
  • ESTRAMUSTINE
  • SACUBITRIL+VALSARTAN
  • TRIAMTERENE
  • AMILORIDE
  • ALISKIREN
  • HEPARIN
  • TRIMETHOPRIM+SULFAMETHOXAZOLE
  • EPLERENONE
  • SPIRONOLACTONE

Special Advise

  • Regular monitoring of blood pressure levels, kidney function and electrolyte levels while taking Amtas PRP Tablet 10's is advised.
  • If you are due to undergo any surgery, inform the doctor that you are taking Amtas PRP Tablet 10's.

Disease/Condition Glossary

High blood pressure (hypertension): It is a condition in which the blood exerts increased pressure on the walls of blood vessels leading to hypertension. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and heart attack (when the blood supply to the heart is blocked). High blood pressure also causes brain damage (stroke) and kidney failure. Symptoms of high blood pressure include headache, dizziness, nose bleed, changes in vision, chest pain, weakness and dyspnoea (shortness of breath). However, most of the time, the signs and symptoms of hypertension are none.

Stable coronary artery disease: It is a condition in which the blood supply to the heart is blocked or reduced. Atherosclerosis (build-up of plaque in the arteries) is the main cause of stable coronary artery disease.

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