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  1. Home
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  3. Asacol 400mg Tablet 10's

Asacol 400mg Tablet 10's, Pack of 10 TABLETS
Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
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Composition :

MESALAZINE-50MG

Manufacturer/Marketer :

Win Medicare Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Asacol 400mg Tablet

Asacol 400mg Tablet belongs to a class of drugs called 'anti-inflammatory drugs used to treat ulcerative colitis and Crohn’s disease. Ulcerative colitis is a type of chronic inflammatory bowel disease that causes inflammation of the large intestine lining (colon). It produces ulcers on the colon's lining, which may cause bleeding and discharge of pus and mucus.

Asacol 400mg Tablet contains Mesalazine, which works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thereby, it reduces inflammation (swelling) in the intestines and provides relief from symptoms such as stomach pain or bleeding.

Take Asacol 400mg Tablet as prescribed. You are advised to use Asacol 400mg Tablet for as long as your doctor has recommended it for you based on your medical condition. In some cases, you may experience diarrhoea, stomach pain, headache, nausea, vomiting or flatulence (gas). Most of these side effects of Asacol 400mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Avoid taking Asacol 400mg Tablet if you are allergic to Mesalazine or any other medicines. Asacol 400mg Tablet should be used with caution in the elderly. If you are pregnant or breastfeeding, please inform your doctor before taking Asacol 400mg Tablet . Mesalazine tablet is not recommended for children below two years, and granules are not recommended for children below six years. However, Asacol 400mg Tablet should be given to children only if advised by a doctor. Avoid taking Asacol 400mg Tablet if you have severe kidney failure. If you have stomach pain or cramps, severe headache, fever or rash, stop taking Asacol 400mg Tablet immediately and consult a doctor.

Uses of Asacol 400mg Tablet

Ulcerative colitis, Crohn’s disease

Directions for Use

Tablet: Take it as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.Granules: Empty the contents directly on the tongue and drink some water or orange juice. They can also be mixed with yoghurt and should be taken immediately without chewing on granules.Pellets: Check the label for directions before use and take it as advised by the doctor.

Medicinal Benefits

Asacol 400mg Tablet contains Mesalazine, an anti-inflammatory drug used in the treatment of ulcerative colitis and Crohn’s disease. It works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thereby helping in reducing inflammation (redness and swelling) in the intestines and providing relief from symptoms such as stomach pain or bleeding. Also, Asacol 400mg Tablet may prevent further episodes of ulcerative colitis.

Storage

Store in a cool and dry place away from sunlight
Side effects of Asacol 400mg Tablet
  • Eating and drinking slowly can help swallow less air, which reduces burps.
  • Avoid consuming foods like gum and hard candy and drinking carbonated drinks as they release carbon dioxide gas in your body.
  • Prevent smoking as it can impact your whole body.
  • Seek medical help to treat gastric problems and heart burn that may lead to frequent burps.
  • Check your dentures because if they are loosely fit, excess air can be swallowed that causes burbs more frequently.
  • If you have bowel inflammation, eat smaller quantities and more frequent meals.
  • Eat slowly and chew your food thoroughly to help digestion.
  • Eat fiber-rich foods such as fruits, whole grains, and vegetables to promote regular bowel movements.
  • Avoid gas-producing foods like cabbage, beans, broccoli and carbonated drinks.
  • Drink lots of water throughout the day to prevent dehydration and aid digestion.
  • Do regular exercise to enhance digestion and reduce bloating.
  • Apply a hot/cold pack to the affected area.
  • Doing gentle exercises can help cope with pain by stretching muscles.
  • Get enough sleep. It helps enhance mood and lower pain sensitivity.
  • Avoid alcohol, smoking and tobacco as they can increase pain.
  • Follow a well-balanced meal.
  • Meditation and massages may also help with pain.
Here are the steps to manage the medication-triggered Common Cold:
  • Inform your doctor about the common cold symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Drink plenty of fluids, such as warm water or soup, to help thin out mucus.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.

Drug Warnings

If you are allergic to Mesalazine or any other medicines, please tell your doctor. Asacol 400mg Tablet should be used with caution in the elderly. If you are pregnant or breastfeeding, please inform your doctor before taking Asacol 400mg Tablet . Mesalazine tablet is not recommended for children below two years, and granules are not recommended for children below six years. However, Asacol 400mg Tablet should be given to children only if advised by a doctor. Avoid taking Asacol 400mg Tablet if you have severe kidney failure. Severe skin reactions such as toxic epidermal necrolysis (skin peeling and blistering) or Stevens-Johnson syndrome (a painful rash that spreads and blisters) can occur in some patients taking Asacol 400mg Tablet . Therefore, if you notice any skin reactions while taking Asacol 400mg Tablet , please consult a doctor immediately. If you have stomach pain or cramps, severe headache, fever or rash, stop taking Asacol 400mg Tablet immediately and consult a doctor. Avoid taking Asacol 400mg Tablet if you have had blood abnormalities or kidney problems while taking other medicines such as Sulphasalazine.

Drug-Drug Interactions

verifiedApollotooltip
MesalazineCidofovir
Critical
MesalazineIomeprol
Severe

Drug-Drug Interactions

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MesalazineCidofovir
Critical
How does the drug interact with Asacol 400mg Tablet:
Co-administration of Asacol 400mg Tablet with Cidofovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Asacol 400mg Tablet with Cidofovir is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience increased or decreased urination, sudden weight gain or loss, shortness of breath, consult a doctor. Do not discontinue any medications without consulting a doctor.
MesalazineIomeprol
Severe
How does the drug interact with Asacol 400mg Tablet:
Co-administration of Iomeprol with Asacol 400mg Tablet may increase the risk of kidney problems.

How to manage the interaction:
Although, there is a possibility of interaction between Asacol 400mg Tablet and Iomeprol they can be taken together if your doctor has prescribed them. Consult a doctor immediately if you experience any symptoms such as swelling in feet and ankles, urinating either too much or too little. Do not discontinue any medication without consulting a doctor.
MesalazineTenofovir alafenamide
Severe
How does the drug interact with Asacol 400mg Tablet:
Co-administration of Tenofovir alafenamide with Asacol 400mg Tablet may increase the risk of kidney problems.

How to manage the interaction:
There is a possibility of interaction between Asacol 400mg Tablet with Tenofovir alafenamide, but they can be taken together if a doctor has prescribed them. Consult a doctor immediately if you experience increased or decreased urination, swelling, shortness of breath, bone pain, cramping in the muscles. Do not discontinue the medication without consulting a doctor.
MesalazineMetrizamide
Severe
How does the drug interact with Asacol 400mg Tablet:
Co-administration of Metrizamide with Asacol 400mg Tablet may increase the risk of kidney problems.

How to manage the interaction:
Although, there is a possibility of interaction between Asacol 400mg Tablet with Metrizamide they can be taken together if a doctor has prescribed them. Consult a doctor immediately if you experience any symptoms such as swelling in feet and ankles, dry, itchy skin, urinating either too much or too little. Do not discontinue any medication without consulting a doctor.
MesalazineOmeprazole
Severe
How does the drug interact with Asacol 400mg Tablet:
Co-administration of omeprazole with Asacol 400mg Tablet can decrease the effects of Asacol 400mg Tablet.

How to manage the interaction:
There could be a possible interaction between Asacol 400mg Tablet and omeprazole, but they can be taken together if a doctor has prescribed them. Do not discontinue any medications without consulting a doctor.
MesalazineNizatidine
Severe
How does the drug interact with Asacol 400mg Tablet:
Co-administration of Nizatidine with Asacol 400mg Tablet can decrease the level or effect of Mesalamine by increasing gastric pH.

How to manage the interaction:
Although there may be a possible interaction between Asacol 400mg Tablet with Nizatidine, they can be taken together if a doctor has prescribed them. Do not discontinue any medications without consulting a doctor.
MesalazineDeferasirox
Severe
How does the drug interact with Asacol 400mg Tablet:
Co-administration of Deferasirox with Asacol 400mg Tablet may increase the risk of kidney problems.

How to manage the interaction:
Although there is a possibility of interaction between Asacol 400mg Tablet and Deferasirox but they can be taken together if a doctor has prescribed them. Consult a doctor immediately if you experience any symptoms such as increased or decreased urination, abrupt weight gain or loss, weakness, or dizziness. Do not discontinue the medication without consulting a doctor.
MesalazineRanitidine
Severe
How does the drug interact with Asacol 400mg Tablet:
Co-administration of Ranitidine with Asacol 400mg Tablet can decrease the levels of Asacol 400mg Tablet, which may be less effective in treating a condition.

How to manage the interaction:
There may be a possible interaction between Asacol 400mg Tablet with Ranitidine, but they can be taken together if a doctor has prescribed them. Do not discontinue any medications without consulting a doctor.
MesalazineIodamide
Severe
How does the drug interact with Asacol 400mg Tablet:
Co-administration of Iodamide with Asacol 400mg Tablet may increase the risk of kidney problems.

How to manage the interaction:
Although, there is a possibility of interaction between Mesalamine with Iodamine they can be taken together if a doctor has prescribed them. Consult a doctor immediately if you experience any symptoms such as swelling in feet and ankles, itchy skin, shortness of breath, urinating either too much or too little. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a low-fat diet and eat foods rich in vitamin C, such as bell peppers, spinach, parsley and berries, which help in healing faster.
  • Include olive oil and omega-3 fatty acids.
  • Eat more fibre-rich foods such as fruits and vegetables.
  • Limit dairy intake as your body may develop difficulty digesting certain dairy products when you are affected with Crohn’s disease, which leads to stomach cramps, diarrhoea or stomach upset.
  • Drink plenty of water to prevent dehydration.

Habit Forming

No

Therapeutic Class

ANTI- INFLAMMATORY AGENTS

Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 8, 2025 | 9:47 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Asacol 400mg Tablet contains Mesalazine, which works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thereby helps in reducing inflammation (swelling) in the intestines and provides relief from symptoms such as stomach pain or bleeding.

Yes, Asacol 400mg Tablet may cause diarrhoea as a common side effect. However, if the condition persists and worsens with fever, watery stools or consistent stomach pain, please consult a doctor. Also, drink plenty of water while taking Asacol 400mg Tablet to prevent dehydration.

You are not recommended to take Asacol 400mg Tablet with Ibuprofen as co-administration of these two medicines may increase the risk of kidney problems. However, please consult your doctor before taking Asacol 400mg Tablet with other medicines.

Yes, Asacol 400mg Tablet may cause kidney stones in some patients. It is not necessary for everyone taking Asacol 400mg Tablet to experience this side effect. However, if you notice blood in urine or pain in the sides of the stomach, please consult a doctor immediately. Drink adequate water while taking Asacol 400mg Tablet to prevent kidney stones.

Asacol 400mg Tablet should be used with caution in patients with stomach ulcers as it may increase the risk of worsening the condition. Therefore, please inform your doctor if you have a stomach ulcer before taking Asacol 400mg Tablet .

Drug-Drug Interactions Checker List

  • LACTULOSE
  • ASPIRIN
  • IBUPROFEN
  • AZATHIOPRINE
  • THIOGUANINE
  • MERCAPTOPURINE

Special Advise

  • Blood and urine tests are recommended before and during the treatment with Asacol 400mg Tablet to monitor the functioning of kidney, liver and blood.

Disease/Condition Glossary

Ulcerative colitis: It is a type of chronic inflammatory bowel disease that causes inflammation of the lining of the large intestine (colon) and produces ulcers on the lining of the colon, which may cause bleeding and discharge of pus and mucus. The common symptoms include bloody stools, stomach pain, rectal pain, diarrhoea, fever or weight loss. Additionally, it may cause other problems such as joint pain or swelling, mouth sores, skin problems, decreased appetite or nausea. The factors involved in causing ulcerative colitis include immune disorders and environmental factors like viruses, bacteria or antigens, which may trigger the immune system and genes inherited from the parent.

Crohn’s disease: It is a type of chronic inflammatory bowel disease that can affect any part of the gastrointestinal tract, from mouth to anus. But mostly occurs in the small intestine and large intestine. The symptoms include blood in stools, stomach cramps, tiredness, diarrhoea, fever, weight loss or loss of appetite.

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