Astin Cv 20 Capsule 10's

Written By Bayyarapu Mahesh Kumar , M Pharmacy

Reviewed By Sunny S , MBBS

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Whats That

About Astin Cv 20 Capsule

Astin Cv 20 Capsule is a combination drug composed of a blood-thinning agent and cholesterol-lowering agent primarily used to prevent heart attack and stroke in the future. It lowers the raised level of cholesterol and fats (triglycerides) in our bodies. A heart attack occurs when your coronary arteries (blood vessels supplying blood and oxygen to the heart) becomes blocked due to the build-up of fats (plaque), including cholesterol. These plaques narrow the arteries, leading to atherosclerosis and coronary artery disease, mainly for most heart attacks.

Astin Cv 20 Capsule is composed of two medicines, namely: Atorvastatin and Clopidogrel. Atorvastatin is a lipid-lowering medication which blocks the enzyme required to make cholesterol in the body. As a result, it lowers the bad cholesterol (low-density lipoproteins or LDL) and triglycerides (TG) and increases the levels of good cholesterol (high-density lipoproteins or HDL). Clopidogrel is a blood thinner (anticoagulant) that collectively prevents a clot in the blood vessels. Together Astin Cv 20 Capsule reduces the increased levels of bad cholesterol (low-density lipoprotein and triglycerides) and prevents blood clots, thereby reducing the risk of heart attack, stroke and heart-related chest pain (angina).

You can take Astin Cv 20 Capsule with food or without food. It should be swallowed whole with a glass of water. Do not chew, bite, or break it. Your doctor will advise you on how often you take this medicine based on your medical condition. You may sometimes experience headaches, ankle swelling (oedema), slow heart rate, and nausea. Astin Cv 20 Capsule is known to cause dizziness, so driving should be avoided. Most of these side effects of Astin Cv 20 Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking a Astin Cv 20 Capsule of your own. Suddenly stopping using Astin Cv 20 Capsule may worsen your condition and increase your risk of a future heart attack. Let your doctor know if you are sensitive to atorvastatin or clopidogrel or have any active liver disease (liver enzyme abnormalities), active bleeding issues (like peptic ulcer, brain haemorrhage), or muscle problem (myopathy, rhabdomyolysis). The patient should inform the doctor they are taking Astin Cv 20 Capsule before any surgery or any new medicine is taken. Atorvastatin, present in Astin Cv 20 Capsule is a pregnancy category X drug, so it should not be given to pregnant women. It may cause harm to the foetus if administered to pregnant or breastfeeding women.

Uses of Astin Cv 20 Capsule

Hyperlipidemia (Increased cholesterol), Prevention of heart attack, Prevention of stroke.

Directions for Use

Swallow the tablet as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Atorvastatin is a lipid-lowering medication that blocks the enzyme required to make cholesterol in the body. As a result, it lowers the bad cholesterol (low-density lipoproteins or LDL) and triglycerides (TG) and increases the levels of good cholesterol (high-density lipoproteins or HDL). Clopidogrel is a blood thinner (anticoagulant) that collectively prevents clot formation in the blood vessels. Together Astin Cv 20 Capsule reduces the increased levels of bad cholesterol (low-density lipoprotein and triglycerides) and prevents blood clots, thereby reducing the risk of heart attack, stroke and heart-related chest pain (angina).

Storage

Keep Astin Cv 20 Capsule out of the sight and reach of children.

Side effects of Astin Cv 20 Capsule

Muscle Pain

Here are the step-by-step strategies to manage the side effects of " Muscle Pain" caused by medication usage:

Report to Your Doctor: Inform your doctor about the muscle pain, as they may need to adjust your medication.
Stretch Regularly: Gentle stretching can help relieve muscle pain and stiffness.
Stay Hydrated: Adequate water intake supports muscle health by removing harmful substances and maintaining proper muscle function.
Warm or Cold Compresses: Apply cold or warm compresses to the affected area to reduce pain and inflammation.
Rest and Relaxation: Adequate rest helps alleviate muscle strain, while relaxation techniques like deep breathing and meditation can soothe muscle tightness, calm the mind, and promote relief from discomfort.
Gentle Exercise: Participate in low-impact activities, such as yoga or short walks, to improve flexibility, reduce muscle tension, and alleviate discomfort.
Consult a physician: If your symptoms don't improve or get worse, go to the doctor for help and guidance.

Joint Pain

Here are the steps to manage Joint Pain caused by medication usage:

Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.

Stomach Pain

Drink water or other clear fluids.
To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
Include bland foods like rice, toast, crackers, and rice in your diet.
Avoid lying down immediately after eating as it may cause indigestion or heartburn.
Avoid acidic and spicy food as it may cause indigestion.

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Constipation

Here are the steps to cope with constipation as a side effect of medication:

Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Dizziness

Here are the 7 steps to manage Dizziness caused by medication:

Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
When standing up, do so slowly and carefully to avoid sudden dizziness.
Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Drug Warnings

Tell your doctor if you are sensitive to Atorvastatin or clopidogrel, have any active liver disease, active bleeding issues (like peptic ulcer, brain haemorrhage), are pregnant or planning to become pregnant or breastfeeding. The patient should inform the doctor that they are taking Astin Cv 20 Capsule before any surgery is scheduled or any new medicine is taken. Atorvastatin present in Astin Cv 20 Capsule is a pregnancy category X drug, so it is contraindicated in pregnant women. As it may cause harm to the foetus if administered to pregnant women. The risk of muscle disease might increase if Astin Cv 20 Capsule is taken with an antibiotic (clarithromycin), anti-HIV drugs (ritonavir, lopinavir, darunavir, atazanavir, indinavir) and antifungal (itraconazole). Coadministration with anticoagulants like warfarin may cause gastric bleeding and other bleeding problems. So, if you are using any blood-thinning agents, let your doctor know about this. Astin Cv 20 Capsule contains Atorvastatin which can cause muscle problems like myopathy and rhabdomyolysis. Patients with active liver disease should use the Astin Cv 20 Capsule with caution. The safety and effectiveness of Astin Cv 20 Capsule have not been established, so its use should be avoided in paediatric patients or children younger than ten years of age. Discontinuation of Astin Cv 20 Capsule may lead to cardiovascular events like heart attack, stroke and angina (heart-related chest pain). Hence, you should consult a doctor before stopping the dose of Astin Cv 20 Capsule .

Drug-Drug Interactions

ClopidogrelSelexipag

Critical

ClopidogrelMifepristone

Critical

Drug-Drug Interactions

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ClopidogrelSelexipag

Critical

How does the drug interact with Astin Cv 20 Capsule:
When Selexipag and Astin Cv 20 Capsule are taken together, the body's ability to break down Selexipag may be reduced.

How to manage the interaction:
Taking Astin Cv 20 Capsule with Selexipag is not recommended, please consult your doctor before taking it. They can be taken if prescribed by your doctor.

ClopidogrelMifepristone

Critical

How does the drug interact with Astin Cv 20 Capsule:
Taking Astin Cv 20 Capsule together with mifepristone increases the risk of vaginal bleeding in women.

How to manage the interaction:
Although taking Astin Cv 20 Capsule with mifepristone is not recommended, that would certainly result in interaction, it can be taken if a doctor prescribes it. If you experience prolonged and heavy bleeding, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.

ClopidogrelTiclopidine

Severe

How does the drug interact with Astin Cv 20 Capsule:
Taking Astin Cv 20 Capsule with ticlopidine can reduced effectiveness of Astin Cv 20 Capsule.

How to manage the interaction:
Taking Astin Cv 20 Capsule and Ticlopidine together possibly has an interaction, but you can take these medications together if your doctor has advised it. Do not stop using any medications without talking to your doctor.

ClopidogrelPonatinib

Severe

How does the drug interact with Astin Cv 20 Capsule:
Using ponatinib together with Astin Cv 20 Capsule may increase the risk of bleeding

How to manage the interaction:
Although taking Astin Cv 20 Capsule and Ponatinib together can cause an interaction, they can be taken together if prescribed by a doctor. However, contact your doctor immediately if you experience bleeding, dizziness, or black stools. Do not discontinue any medications without consulting your doctor.

ClopidogrelPanobinostat

Severe

How does the drug interact with Astin Cv 20 Capsule:
Taking Astin Cv 20 Capsule together with Panobinostat can increases the risk of bleeding.

How to manage the interaction:
Although taking Astin Cv 20 Capsule together with panobinostat can result in interaction, it can be taken if prescribed by a doctor. However, consult your doctor immediately if you experience dizziness, lightheadedness, redness or blackness, sticky stools, or severe headache. Do not discontinue any medication without consulting your doctor.

ClopidogrelRepaglinide

Severe

How does the drug interact with Astin Cv 20 Capsule:
Astin Cv 20 Capsule increases the blood levels of Repaglinide, which results in increased effectiveness of Repaglinide. When these medicines are taken together, you may experience low blood sugar (hypoglycemia).

How to manage the interaction:
Although taking Astin Cv 20 Capsule with Repaglinide may result in interaction, it can be taken if prescribed by a doctor. However, if you experience any signs of hypoglycemia (low blood sugar), consult your doctor immediately. Common symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, weakness, tremor, nausea, hunger, sweating, and palpitation. It is advised to monitor your blood sugar levels if you experience the above symptoms. Do not discontinue any medication without consulting a doctor.

ClopidogrelDefibrotide

Severe

How does the drug interact with Astin Cv 20 Capsule:
Taking Astin Cv 20 Capsule with Defibrotide can increase the risk of bleeding.

How to manage the interaction:
Although taking Astin Cv 20 Capsule and Defibrotide together can cause an interaction, it can be taken if your doctor has suggested it. However, consult a doctor if you experience bleeding, bruising, feeling dizzy or lightheaded, having black or tarry stools, experiencing a severe headache, feeling weak, or having bleeding or vomiting. Do not discontinue any medications without first consulting your doctor.

ClopidogrelPrasugrel

Severe

How does the drug interact with Astin Cv 20 Capsule:
Taking Astin Cv 20 Capsule together with Prasugrel will have an additive effect and increase the risk of bleeding.

How to manage the interaction:
Although taking Astin Cv 20 Capsule together with Prasugrel may result in interaction, it can be taken if prescribed by a doctor. However, If you experience any unusual bleeding or have other signs of bleeding like feeling dizzy or lightheaded, red or black, sticky stools, or having a severe headache, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.

ClopidogrelProtamine

Severe

How does the drug interact with Astin Cv 20 Capsule:
Taking Protamine with Astin Cv 20 Capsule can increase the risk of bleeding.

How to manage the interaction:
Taking Protamine with Astin Cv 20 Capsule together can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.

ClopidogrelLoperamide

Severe

How does the drug interact with Astin Cv 20 Capsule:
Taking loperamide with Astin Cv 20 Capsule may significantly increase the blood levels of loperamide. This can lead to serious and complications such as irregular heart rhythm.

How to manage the interaction:
Although talking Astin Cv 20 Capsule with loperamide may result in an interaction, it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, or shortness of breath. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Low cholesterol diet along with a regular exercise regime is found to complement treatment with Astin Cv 20 Capsule effectively.
Stick to a freshly prepared home-cooked meal and avoid processed, packed foods that contain hidden sugar and extra calories.
Try to replace most of your saturated fats with unsaturated fats to reduce total cholesterol and LDL cholesterol (bad cholesterol) quickly.
Foods like avocados, olive oil, fatty fish and nuts contain many heart-healthy unsaturated fats, so eating them regularly is beneficial.
Include a diet enriched in fats like fish oils, polyunsaturated oils, and omega-3 fatty acids, which are good for heart health.
Quit smoking and avoid excessive intake of alcohol.

Side Effects of Astin Cv 20 Capsule

Bleeding (stomach, gastrointestinal, nose bleeding)
Rash
Diarrhoea
Stomach ulcer
Muscle disease (like myopathy, rhabdomyolysis)
Abdominal pain

Habit Forming

No

Therapeutic Class

CARDIOVASCULAR AGENTS

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Author Details

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Reviewed By

Sunny S

MBBS

Last Updated

Jul 8, 2025 | 9:29 AM IST

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Can Astin Cv 20 Capsule cause blood thinning?

Yes, Astin Cv 20 Capsule contains clopidogrel which prevents blood clotting. It works by preventing platelets (a type of blood cell) from sticking together and forming clots which in turn prevents the risk of heart attack and stroke.

Can taking Astin Cv 20 Capsule increase the risk of bleeding?

Yes, taking Astin Cv 20 Capsule can increase the risk of bleeding as it contains aspirin and clopidogrel which belongs to a class of blood-thinning agents. So, please be very cautious while shaving, cutting fingernails or toenails, or using sharp objects to avoid any bleeding. Let your doctor know before going any surgical procedure, that you are taking Astin Cv 20 Capsule .

Is Astin Cv 20 Capsule safe for pregnant mother and fetus?

No. Astin Cv 20 Capsule contains Atorvastatin which is pregnancy category X medicine and can cause harm to both pregnant mother and unborn baby. Even if you are planning for pregnancy tell your doctor that you are using Astin Cv 20 Capsule .

Does intake of Astin Cv 20 Capsule affects muscle?

Yes, prolonged use of Astin Cv 20 Capsule may cause muscle diseases like myopathy and rhabdomyolysis. So if you feel any musculoskeletal pain after taking Astin Cv 20 Capsule consult your doctor about this issue.

What foods should I avoid when taking Astin Cv 20 Capsule ?

Do not drink grapefruit juice while taking Astin Cv 20 Capsule . Grapefruit juice may increase the blood-thinning effect of your medicine.

Can I drink alcohol with Astin Cv 20 Capsule ?

Drinking alcohol with Astin Cv 20 Capsule may damage your liver and increase liver enzymes like transaminase. So, Astin Cv 20 Capsule should be used with caution who consume alcohol and/or have past history of liver disease.

What will happen if I accidentally take overdosage of Astin Cv 20 Capsule ?

If you accidentally take an overdose of Astin Cv 20 Capsule you may have liver problems (increased secretion of liver enzymes) and bleeding complications. If problems persist you should immediately go to the nearby clinic or hospital.

Which are the tests required after using Astin Cv 20 Capsule ?

You should have a total lipid profile (TG, HDL, LDL, VLDL, TC) and Blood coagulation tests like Complete blood count (CBC), Factor V assay, Fibrinogen Test, Prothrombin time (PT or PT-INR), Platelet count, Thrombin time and Bleeding time to analyze your blood clot timing and cholesterol level.

Drug-Drug Interactions Checker List

CLARITHROMYCIN
RITONAVIR
LOPINAVIR
DARUNAVIR
ATAZANAVIR
INDINAVIR
ITRACONAZOLE
WARFARIN
COUMADIN
HEPARIN
COLCHICINE
DIGOXIN
CYCLOSPORINE

Special Advise

If you have a high cholesterol level, try to have a lipid profile test (LFT) every 6 months.

Disease/Condition Glossary

Atherosclerosis: Atherosclerosis occurs when fats, cholesterol, and other substances known as plaque deposit on your artery walls that restrict blood flow. This plaque formation triggers blood clots, narrows the arteries' size, and hardens them. This, in turn, can lead to various heart complications like atherosclerosis, heart attack, heart-related chest pain (angina), and stroke. However, it can also affect the body's arteries apart from the heart.