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  3. Clopitorva 20 Capsule 10's

Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
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Manufacturer/Marketer :

Zydus Healthcare Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Clopitorva 20 Capsule

Clopitorva 20 Capsule is a combination drug composed of a blood-thinning agent and cholesterol-lowering agent primarily used to prevent heart attack and stroke in the future. It lowers the raised level of cholesterol and fats (triglycerides) in our bodies. A heart attack occurs when your coronary arteries (blood vessels supplying blood and oxygen to the heart) becomes blocked due to the build-up of fats (plaque), including cholesterol. These plaques narrow the arteries, leading to atherosclerosis and coronary artery disease, mainly for most heart attacks.

Clopitorva 20 Capsule is composed of two medicines, namely: Atorvastatin and Clopidogrel. Atorvastatin is a lipid-lowering medication which blocks the enzyme required to make cholesterol in the body. As a result, it lowers the bad cholesterol (low-density lipoproteins or LDL) and triglycerides (TG) and increases the levels of good cholesterol (high-density lipoproteins or HDL). Clopidogrel is a blood thinner (anticoagulant) that collectively prevents a clot in the blood vessels. Together Clopitorva 20 Capsule reduces the increased levels of bad cholesterol (low-density lipoprotein and triglycerides) and prevents blood clots, thereby reducing the risk of heart attack, stroke and heart-related chest pain (angina).

You can take Clopitorva 20 Capsule with food or without food. It should be swallowed whole with a glass of water. Do not chew, bite, or break it. Your doctor will advise you on how often you take this medicine based on your medical condition. You may sometimes experience headaches, ankle swelling (oedema), slow heart rate, and nausea. Clopitorva 20 Capsule is known to cause dizziness, so driving should be avoided. Most of these side effects of Clopitorva 20 Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking a Clopitorva 20 Capsule of your own. Suddenly stopping using Clopitorva 20 Capsule may worsen your condition and increase your risk of a future heart attack. Let your doctor know if you are sensitive to atorvastatin or clopidogrel or have any active liver disease (liver enzyme abnormalities), active bleeding issues (like peptic ulcer, brain haemorrhage), or muscle problem (myopathy, rhabdomyolysis). The patient should inform the doctor they are taking Clopitorva 20 Capsule before any surgery or any new medicine is taken. Atorvastatin, present in Clopitorva 20 Capsule is a pregnancy category X drug, so it should not be given to pregnant women. It may cause harm to the foetus if administered to pregnant or breastfeeding women.

Uses of Clopitorva 20 Capsule

Hyperlipidemia (Increased cholesterol), Prevention of heart attack, Prevention of stroke.

Directions for Use

Swallow the tablet as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Atorvastatin is a lipid-lowering medication that blocks the enzyme required to make cholesterol in the body. As a result, it lowers the bad cholesterol (low-density lipoproteins or LDL) and triglycerides (TG) and increases the levels of good cholesterol (high-density lipoproteins or HDL). Clopidogrel is a blood thinner (anticoagulant) that collectively prevents clot formation in the blood vessels. Together Clopitorva 20 Capsule reduces the increased levels of bad cholesterol (low-density lipoprotein and triglycerides) and prevents blood clots, thereby reducing the risk of heart attack, stroke and heart-related chest pain (angina).

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Tell your doctor if you are sensitive to Atorvastatin or clopidogrel, have any active liver disease, active bleeding issues (like peptic ulcer, brain haemorrhage), are pregnant or planning to become pregnant or breastfeeding. The patient should inform the doctor that they are taking Clopitorva 20 Capsule before any surgery is scheduled or any new medicine is taken. Atorvastatin present in Clopitorva 20 Capsule is a pregnancy category X drug, so it is contraindicated in pregnant women. As it may cause harm to the foetus if administered to pregnant women. The risk of muscle disease might increase if Clopitorva 20 Capsule is taken with an antibiotic (clarithromycin), anti-HIV drugs (ritonavir, lopinavir, darunavir, atazanavir, indinavir) and antifungal (itraconazole). Coadministration with anticoagulants like warfarin may cause gastric bleeding and other bleeding problems. So, if you are using any blood-thinning agents, let your doctor know about this. Clopitorva 20 Capsule contains Atorvastatin which can cause muscle problems like myopathy and rhabdomyolysis. Patients with active liver disease should use the Clopitorva 20 Capsule with caution. The safety and effectiveness of Clopitorva 20 Capsule have not been established, so its use should be avoided in paediatric patients or children younger than ten years of age. Discontinuation of Clopitorva 20 Capsule may lead to cardiovascular events like heart attack, stroke and angina (heart-related chest pain). Hence, you should consult a doctor before stopping the dose of Clopitorva 20 Capsule .

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Clopitorva 20 Capsule:
When Selexipag and Clopitorva 20 Capsule are taken together, the body's ability to break down Selexipag may be reduced.

How to manage the interaction:
Taking Clopitorva 20 Capsule with Selexipag is not recommended, please consult your doctor before taking it. They can be taken if prescribed by your doctor.
How does the drug interact with Clopitorva 20 Capsule:
Taking Clopitorva 20 Capsule together with mifepristone increases the risk of vaginal bleeding in women.

How to manage the interaction:
Although taking Clopitorva 20 Capsule with mifepristone is not recommended, that would certainly result in interaction, it can be taken if a doctor prescribes it. If you experience prolonged and heavy bleeding, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Clopitorva 20 Capsule:
Taking Clopitorva 20 Capsule with Posaconazole can increase the blood levels of Clopitorva 20 Capsule. This can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between posaconazole with Clopitorva 20 Capsule, they can be taken together if advised by your doctor. However, contact the doctor if you experience unexplained muscle pain, weakness, fever, chills, joint pain or swelling, unusual bleeding, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark coloured urine, or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Clopitorva 20 Capsule:
Taking Pioglitazone with Clopitorva 20 Capsule can increases the blood levels of Pioglitazone, when these medicines are taken together, you may experience hypoglycemia (low blood sugar).

How to manage the interaction:
Taking Clopitorva 20 Capsule together with Pioglitazone may lead to interaction, but it can be taken if prescribed by your doctor. Consult a doctor immediately if you experience headache, dizziness, drowsiness, nervousness, weakness, shaking, or sweating. Do not discontinue any medication without consulting the doctor.
How does the drug interact with Clopitorva 20 Capsule:
Coadministration of Clopitorva 20 Capsule with Esomeprazole may reduce the effectiveness of Clopitorva 20 Capsule.

How to manage the interaction:
Taking Clopitorva 20 Capsule and esomeprazole together possibly has an interaction, but you can take these medications together if your doctor has advised it. Do not stop using any medications without talking to your doctor.
ClopidogrelPonatinib
Severe
How does the drug interact with Clopitorva 20 Capsule:
Using ponatinib together with Clopitorva 20 Capsule may increase the risk of bleeding

How to manage the interaction:
Although taking Clopitorva 20 Capsule and Ponatinib together can cause an interaction, they can be taken together if prescribed by a doctor. However, contact your doctor immediately if you experience bleeding, dizziness, or black stools. Do not discontinue any medications without consulting your doctor.
ClopidogrelTipranavir
Severe
How does the drug interact with Clopitorva 20 Capsule:
Taking Tipranavir with Clopitorva 20 Capsule can make the blood-thinning effects of Clopitorva 20 Capsule stronger.

How to manage the interaction:
Although there is a possible interaction between Clopitorva 20 Capsule and Tipranavir, you can take these medicines together if prescribed by your doctor. If you notice any bleeding, severe headaches, weakness, or black stools, contact your doctor right away. Do not stop using any medications without talking to your doctor.
How does the drug interact with Clopitorva 20 Capsule:
Taking Clopitorva 20 Capsule together with Panobinostat can increases the risk of bleeding.

How to manage the interaction:
Although taking Clopitorva 20 Capsule together with panobinostat can result in interaction, it can be taken if prescribed by a doctor. However, consult your doctor immediately if you experience dizziness, lightheadedness, redness or blackness, sticky stools, or severe headache. Do not discontinue any medication without consulting your doctor.
ClopidogrelDesirudin
Severe
How does the drug interact with Clopitorva 20 Capsule:
Using desirudin together with Clopitorva 20 Capsule may increase the risk of bleeding.

How to manage the interaction:
Taking Clopitorva 20 Capsule with Desirudin together can result in an interaction, but it can be taken if your doctor has advised it. However, consult a doctor if you experience difficulty with bleeding, bleeding, bruising, feeling dizzy or lightheaded, dark or sticky stools, headache, or vomiting. Do not stop using any medications without a doctor's advice.
How does the drug interact with Clopitorva 20 Capsule:
The use of ramucirumab together with Clopitorva 20 Capsule may raise the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Clopitorva 20 Capsule and Ramucirumab, you can take these medicines together if prescribed by your doctor. If you notice these signs, contact your doctor immediately - feeling dizzy or lightheaded, dark or bloody stools, coughing, intense headaches, or weakness. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Low cholesterol diet along with a regular exercise regime is found to complement treatment with Clopitorva 20 Capsule effectively.
  • Stick to a freshly prepared home-cooked meal and avoid processed, packed foods that contain hidden sugar and extra calories.
  • Try to replace most of your saturated fats with unsaturated fats to reduce total cholesterol and LDL cholesterol (bad cholesterol) quickly.
  • Foods like avocados, olive oil, fatty fish and nuts contain many heart-healthy unsaturated fats, so eating them regularly is beneficial.
  • Include a diet enriched in fats like fish oils, polyunsaturated oils, and omega-3 fatty acids, which are good for heart health.
  • Quit smoking and avoid excessive intake of alcohol.

Habit Forming

No

Therapeutic Class

CARDIOVASCULAR AGENTS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Drug-Drug Interactions Checker List

  • CLARITHROMYCIN
  • RITONAVIR
  • LOPINAVIR
  • DARUNAVIR
  • ATAZANAVIR
  • INDINAVIR
  • ITRACONAZOLE
  • WARFARIN
  • COUMADIN
  • HEPARIN
  • COLCHICINE
  • DIGOXIN
  • CYCLOSPORINE

Special Advise

  • If you have a high cholesterol level, try to have a lipid profile test (LFT) every 6 months.

 

Disease/Condition Glossary

Atherosclerosis: Atherosclerosis occurs when fats, cholesterol, and other substances known as plaque deposit on your artery walls that restrict blood flow. This plaque formation triggers blood clots, narrows the arteries' size, and hardens them. This, in turn, can lead to various heart complications like atherosclerosis, heart attack, heart-related chest pain (angina), and stroke. However, it can also affect the body's arteries apart from the heart.

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