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Written By Urvashi Bharti , MBBS
Reviewed By Sureshvarma D , MPharma

About Atacurium 25 mg Injection 2.5 ml

Atacurium 25 mg Injection 2.5 ml belongs to the group of medicines called skeletal muscle relaxants used to reduce and relieve muscle spasms (excessive tension in the muscles) occurring during surgery in intensive care. Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms.

Atacurium 25 mg Injection 2.5 ml contains ‘Atracurium’ that works by blocking the action of acetylcholine on skeletal muscles. Thus, stop sending a pain signal to the brain, relieving muscle stiffness or muscle spasm along with pain and surgery. Atacurium 25 mg Injection 2.5 ml is used during surgery.  It is also used during general anaesthesia to ease tracheal intubation (a tube into the windpipe) and controlled ventilation.

Atacurium 25 mg Injection 2.5 ml is given by the healthcare professional during surgery.  In some cases, you may experience tachycardia (rapid heartbeat), temporary hypotension (low blood pressure), wheezing, bronchospasm (asthma-like symptoms), skin flushing, and urticaria (nettle rash). Most of these side effects of Atacurium 25 mg Injection 2.5 ml do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Before receiving Atacurium 25 mg Injection 2.5 ml inform your doctor if you have had myasthenia gravis or Eaton-Lambert syndrome,  severe electrolyte disorder, asthma-like symptoms (a history of allergy, asthma or bronchospasm), burns and lack of adequate circulatory filling (hypovolaemia), pregnant or breastfeeding mother. Your doctor will prescribe Atacurium 25 mg Injection 2.5 ml only if the benefits outweigh the risks. Atacurium 25 mg Injection 2.5 ml is not recommended in neonates (children under the age of one month). Atacurium 25 mg Injection 2.5 ml is a cold chain medicine, and so it has to be stored in the refrigerator between 2-8 degrees Celsius else its efficiency might get lost. Do not store in the freezer or the fridge.

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Whats That

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Non returnable*
COD available

Online payment accepted

Composition

ATRACURIUM-25MG

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

Uses of Atacurium 25 mg Injection 2.5 ml

Muscle contraction during surgery

Medicinal Benefits

Atacurium 25 mg Injection 2.5 ml belongs to the group of medicines called muscle relaxants used to reduce and relieve muscle contraction (excessive tension in the muscles) during surgery, other procedures, and in intensive care. It is also used to calm muscles while on a breathing machine, during general anaesthesia to ease tracheal intubation (a tube into the windpipe), and controlled ventilation. It works by blocking the action of acetylcholine on skeletal muscles. Also, stop sending a pain signal to the brain, relieving muscle stiffness or muscle spasm along with pain and surgery. An experienced doctor must give Atacurium 25 mg Injection 2.5 ml under carefully controlled conditions. It is used during procedures that require that the patient is fully anaesthetized (unconscious) or heavily sedated.

Side Effects of Atacurium 25 mg Injection 2.5 ml

  • Tachycardia (rapid heartbeat)
  • Temporary hypotension (low blood pressure)
  • Wheezing
  • Bronchospasm (asthma-like symptoms)
  • Skin flushing
  • Urticaria (nettle rash)

Directions for Use

A healthcare professional will administer Atacurium 25 mg Injection 2.5 ml under carefully controlled conditions. Do not self-administer Atacurium 25 mg Injection 2.5 ml.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Before you receive Atacurium 25 mg Injection 2.5 ml, tell your doctor if you have a disease that affects the muscles and nervous control (neuromuscular disease such as myasthenia gravis or Eaton-Lambert syndrome (muscle disorder)), a severe electrolyte disorder, cancer spread widely from a primary source (carcinomatosis), a sensitivity to histamine, asthma-like symptoms (a history of allergy, asthma or bronchospasm), burns, lack of adequate circulatory filling (hypovolaemia). Atacurium 25 mg Injection 2.5 ml should not be given to pregnant women unless prescribed. If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking Atacurium 25 mg Injection 2.5 ml. Mothers should stop breastfeeding for 24 hours after receiving Atacurium 25 mg Injection 2.5 ml. Atacurium 25 mg Injection 2.5 ml is not recommended in neonates (children under the age of one month) as safety and effectiveness in pediatric patients below the age of 1 month have not been established. Atacurium 25 mg Injection 2.5 ml some formulations containing benzyl alcohol. In neonates, benzyl alcohol has been associated with an increased incidence of neurological and other complications, sometimes fatal.

Therapeutic Class

MUSCLE RELAXANTS/SKELETAL MUSCLE RELAXANTS

Drug-Drug Interactions

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AtracuriumBotulinum toxin
Severe
AtracuriumFentanyl
Severe

Drug-Drug Interactions

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AtracuriumBotulinum toxin
Severe
How does the drug interact with Atacurium 25 mg Injection 2.5 ml:
Coadministration of Botulinum toxin with Atacurium 25 mg Injection 2.5 ml may increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Botulinum toxin and Atacurium 25 mg Injection 2.5 ml, it can be taken if prescribed by a doctor. However, contact a doctor immediately if you experience excessive muscle weakness or trouble breathing, swallowing, or speaking. Do not discontinue any medications without consulting a doctor.
AtracuriumFentanyl
Severe
How does the drug interact with Atacurium 25 mg Injection 2.5 ml:
Combining Atacurium 25 mg Injection 2.5 ml with Fentanyl can increase the risk of irregular heart rhythm and low blood pressure.

How to manage the interaction:
There may be a possibility of interaction between Atacurium 25 mg Injection 2.5 ml and Fentanyl, but it can be taken if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
AtracuriumStreptomycin
Severe
How does the drug interact with Atacurium 25 mg Injection 2.5 ml:
Co-administration of Streptomycin with Atacurium 25 mg Injection 2.5 ml may increase the risk or severity of side effects.

How to manage the interaction:
Co-administration of Streptomycin with Atacurium 25 mg Injection 2.5 ml can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without first consulting your doctor.
AtracuriumAmikacin
Severe
How does the drug interact with Atacurium 25 mg Injection 2.5 ml:
Co-administration of Amikacin with Atacurium 25 mg Injection 2.5 ml can increase the risk of developing breathing difficulties.

How to manage the interaction:
Taking Atacurium 25 mg Injection 2.5 ml with Amikacin together can result in an interaction, but it can be taken if your doctor has advised it. Consult your doctor if you experience shortness of breath, palpitations, chest discomfort, or dizziness. Do not discontinue any medications without consulting a doctor.
AtracuriumPolymyxin b
Severe
How does the drug interact with Atacurium 25 mg Injection 2.5 ml:
Co-administration of Polymyxin B with Atacurium 25 mg Injection 2.5 ml may cause serious breathing problems

How to manage the interaction:
There may be a possibility of interaction between Polymyxin b and Atacurium 25 mg Injection 2.5 ml, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, consult the doctor. Do not stop using any medications without a doctor's advice.
AtracuriumTobramycin
Severe
How does the drug interact with Atacurium 25 mg Injection 2.5 ml:
Using Atacurium 25 mg Injection 2.5 ml with Tobramycin can increase the risk of respiratory depression (breathing disorder).

How to manage the interaction:
Although there is a interaction between Tobramycin and Atacurium 25 mg Injection 2.5 ml, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to your doctor.
AtracuriumClindamycin
Severe
How does the drug interact with Atacurium 25 mg Injection 2.5 ml:
Co-administration of Clindamycin with Atacurium 25 mg Injection 2.5 ml can increase the risk of muscle weakness.

How to manage the interaction:
Taking Clindamycin with Atacurium 25 mg Injection 2.5 ml together can possibly result in an interaction, but it can be taken if a doctor has advised it. "Clindamycin can affect the muscles and nerves in your body. When used with other medications that also affect the muscles and nerves, it can cause a serious problem called neuromuscular blockade. If you have trouble breathing or can't breathe at all, please call your doctor right away." Do not stop using any medications without a doctor's advice.
AtracuriumDoxycycline
Severe
How does the drug interact with Atacurium 25 mg Injection 2.5 ml:
Co-administration of Atacurium 25 mg Injection 2.5 ml with doxycycline may increase the risk of breathing problems.

How to manage the interaction:
Although there is an interaction between Atacurium 25 mg Injection 2.5 ml and Doxycycline, bit it can be taken together if prescribed by your doctor. Do not stop using any medications without first talking to your doctor.
AtracuriumStreptomycin
Severe
How does the drug interact with Atacurium 25 mg Injection 2.5 ml:
Co-administration of Streptomycin with Atacurium 25 mg Injection 2.5 ml may increase the neuromuscular blocking effects of Atacurium 25 mg Injection 2.5 ml.

How to manage the interaction:
Co-administration of Streptomycin with Atacurium 25 mg Injection 2.5 ml can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without first consulting your doctor.
AtracuriumColistin
Severe
How does the drug interact with Atacurium 25 mg Injection 2.5 ml:
Coadministration of Atacurium 25 mg Injection 2.5 ml with Colistin can increase the risk of Atacurium 25 mg Injection 2.5 ml side effects.

How to manage the interaction:
Although there is a possible interaction between Colistin and Atacurium 25 mg Injection 2.5 ml, you can take these medicines together if prescribed by your doctor. However, if you experience an upset stomach, rash, dizziness, slurred speech, or fever, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • POLYMYXIN B
  • TETRACYCLINE
  • LINCOMYCIN
  • CLINDAMYCIN
  • VANCOMYCIN
  • LIDOCAINE
  • PROCAINAMIDE
  • QUININE
  • FUROSEMIDE
  • ACETAZOLAMIDE
  • PROPRANOLOL
  • DILTIAZEM
  • NIFEDIPINE
  • VERAPAMIL
  • CARBAMAZEPINE
  • PHENYTOIN
  • CHLOROQUINE
  • PENICILLAMINE
  • BECLOMETASONE
  • BUDESONIDE
  • PREDNISOLONE
  • FLUTICASONE
  • MOMETASONE
  • TRIAMCINOLONE
  • DANTROLENE
  • KETAMINE
  • LITHIUM
  • CHLORPROMAZINE
  • SPECTINOMYCIN
  • MANNITOL
  • TRIMETAPHAN
  • HEXAMETHONIUM

Diet & Lifestyle Advise

  • Avoid freezing and hot temperatures.

  • Avoid wearing tight-fitting clothes. Instead, wear loose garments.

  • Rest well, and get plenty of sleep.

  • To avoid developing pressure sores, change your position every two hours.

  • Hot or cold therapy can help treat muscle spasms. Apply an ice pack or hot pack on the muscle for 15-20minutes.

  • Stay hydrated, and drink plenty of water.

Habit Forming

No

Special Advise

An experienced healthcare professional must only give Atacurium 25 mg Injection 2.5 ml under carefully controlled conditions.

Author Details

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Disease/Condition Glossary

Muscle spasm (contraction): It is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms. Symptoms include muscle tightness, joint stiffness, unusual posture, difficulty moving, and pain in affected muscles and joints. Muscle relaxants can treat muscle spasms. Muscle relaxants sedate the muscle and help in inhibiting painful contractions. Muscle weakness is common in the surgical intensive care unit (ICU). Surgical procedures can affect the respiratory muscles through many mechanisms, including thoracoabdominal mechanics (affecting the thorax and the abdomen), reflexes, neuromechanical coupling, and loss of muscular integrity. Impairment of respiratory muscle function after surgery may lead to postoperative complications such as hypoventilation (a state in which a reduced amount of air enters the lungs), hypoxia (an absence of enough oxygen in the tissues), atelectasis (Complete or partial collapse of a lung), and infections, some of which may be life-threatening.

Atacurium 25 mg Injection 2.5 ml Substitute

Substitutes safety advice
  • Arium 25 mg Injection 2.5 ml

    66.22per tablet
  • Crimat 25 mg Injection 2.5 ml

    by AYUR

    21.15per tablet
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