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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Whats That

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Synonym :

ATAZANAVIR SULPHATE

Composition :

ATAZANAVIR-300MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Atavir 300mg Capsule

Atavir 300mg Capsule is an antiretroviral medicine used in the treatment of HIV infection. HIV is a retroviral infection that attacks and destroys immune cells. This reduces the body's ability to fight infections and illnesses. If this condition is left untreated, it can lead to Acquired Immuno Deficiency Syndrome (AIDS). Symptoms of HIV include fever, chills, night sweats, muscle aches, etc.

Atavir 300mg Capsule contains Atazanavir, which belongs to the class of protease inhibitors. It works by inhibiting the protease enzyme production, which is required for the HIV-infected cells to make new viruses. This causes inhibition of viral replication.

Atavir 300mg Capsule may cause certain side effects such as nausea, headache, stomach pain, loss of appetite, vomiting, depression, fever, tiredness, back pain, blood in urine, diarrhea, muscle pain, dizziness, and allergic reactions. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. Atavir 300mg Capsule should be taken as advised by your doctor. Your doctor will decide the dose of the medicine based on your health condition. Do not take more than the recommended dose.

Atavir 300mg Capsule should be avoided if you are allergic to it. It is contraindicated in patients with Stevens-Johnson syndrome, erythema multiforme or patients taking alfuzosin, triazolam, orally administered midazolam, ergot derivatives, rifampin, irinotecan, lovastatin, simvastatin, indinavir, cisapride, pimozide, as it can cause serious side effects. Hence avoid using this medicine under such conditions. Inform your doctor if you have any cardiovascular conditions, liver/kidney disease, diabetes, or immune reconstitution syndrome on priority. Atavir 300mg Capsule should be given to pregnant and breastfeeding women only if recommended by the doctor. Atavir 300mg Capsule is not recommended for children below six years of age as safety and efficacy are not established.

Uses of Atavir 300mg Capsule

HIV Infection

Directions for Use

Take Atavir 300mg Capsule as advised by your doctor. It can be taken with or without food. Swallow as a whole with a glass of water. Do not chew or crush or break the medicine.

Medicinal Benefits

Atavir 300mg Capsule contains Atazanavir, which belongs to the class of protease inhibitors. It works by inhibiting the protease enzyme production, which is required for the HIV-infected cells to make new viruses. This causes inhibition of viral replication. Atavir 300mg Capsule is used alone or in combination with other antiretroviral medicines to help reduce the symptoms, control the infection, and prevent opportunistic infections effectively. It also helps in improving the quality of life of a patient with HIV. 

Storage

Store in a cool and dry place away from sunlight
Side effects of Atavir 300mg Capsule
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Maintain a healthy diet with fruits, whole grains, and vegetables.
  • Include easy-to-digest and antioxidant-rich food in your diet.
  • Drink plenty of water and unsweetened liquids.
  • Limit sugary foods, alcohol, refined carbs and fried foods.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.

Drug Warnings

Atavir 300mg Capsule should be avoided if you are allergic to it. It is contraindicated in patients with Stevens-Johnson syndrome, erythema multiforme or patients taking alfuzosin, triazolam, orally administered midazolam, ergot derivatives, rifampin, irinotecan, lovastatin, simvastatin, indinavir, cisapride, pimozide, as it can cause serious side effects. Hence avoid using this medicine under such conditions. Inform your doctor if you have any cardiovascular conditions, liver/kidney disease, diabetes, or immune reconstitution syndrome on priority. Atavir 300mg Capsule should be given to pregnant and breastfeeding women only if recommended by the doctor. Atavir 300mg Capsule is not recommended for children below six years of age as safety and efficacy are not established. This medicine may cause dizziness; hence avoid driving or operating machines while taking Atavir 300mg Capsule.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Atavir 300mg Capsule:
When Atavir 300mg Capsule is taken with Nimodipine, it can increase the risk of side effects.

How to manage the interaction:
Taking Nimodipine with Atavir 300mg Capsule is not recommended, as it can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience irregular heart rhythm, swelling, and low blood pressure, consult the doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Atavir 300mg Capsule:
When Tolvaptan and Atavir 300mg Capsule are taken together, may significantly increase the blood levels and effects of Tolvaptan.

How to manage the interaction:
There may be a possibility of interaction between Tolvaptan and Atavir 300mg Capsule, but it can be taken if prescribed by a doctor. If you notice any of these signs -difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, seizures, call a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Atavir 300mg Capsule:
Atavir 300mg Capsule and Midazolam co-administration may considerably enhance Midazolam blood levels and effects.

How to manage the interaction:
Although taking Atavir 300mg Capsule and Midazolam together may result in an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have excessive or prolonged sleepiness and breathing issues. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Atavir 300mg Capsule:
Co-administration of Atavir 300mg Capsule and Silodosin together can increase the effectiveness of Silodosin which may lead to side effects including extremely low blood pressure, increased heart rate.

How to manage the interaction:
Taking Atavir 300mg Capsule and Silodosin together is not recommended as it can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, or heart palpitation, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Atavir 300mg Capsule:
Combining Atavir 300mg Capsule and Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver damage and rhabdomyolysis( involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Atavir 300mg Capsule and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark-coloured urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Atavir 300mg Capsule:
Concomitant use of Alfuzosin with Atavir 300mg Capsule can increase the risk of low blood pressure.

How to manage the interaction:
Coadministration of Alfuzosin with Atavir 300mg Capsule is not recommended, however, it can be taken if your doctor has advised it. Contact your doctor immediately if you experience dizziness, palpitations, difficulty swallowing, or sweating. It is recommended to monitor your blood pressure regularly. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Atavir 300mg Capsule:
Combining Atavir 300mg Capsule and Sildenafil can increase the blood levels and side effects of sildenafil.

How to manage the interaction:
Taking Atavir 300mg Capsule and Sildenafil together is avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Atavir 300mg Capsule:
When Atavir 300mg Capsule is taken with Nevirapine, it can reduce the levels and side effects of Atavir 300mg Capsule & increase the blood levels and effects of nevirapine.

How to manage the interaction:
Taking Nevirapine with Atavir 300mg Capsule is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience a rash on any parts of your body, loss of appetite, nausea, vomiting, jaundice (yellowing of the skin and/or eyes), dark-coloured urine, pale-coloured stools, or pain or ache in the right abdominal area below your ribs, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Atavir 300mg Capsule:
Taking bosutinib with Atavir 300mg Capsule may increase the blood levels of bosutinib. This can increase side effects such as nausea, vomiting, abdominal pain, and diarrhea.

How to manage the interaction:
Although there is an interaction between Bosutinib and Atavir 300mg Capsule, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fatigue, dizziness, fainting, fever, chills, diarrhea, sore throat, muscle aches, red or inflamed skin, and pain or burning during urination. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Atavir 300mg Capsule:
Coadministration of Colchicine with Atavir 300mg Capsule results in increased colchicine levels in the blood, leading to increased side effects of Colchicine.

How to manage the interaction:
Although taking Colchicine and Atavir 300mg Capsule together may result in an interaction, they can be taken together if your doctor prescribes it. However, if you experience any signs and symptoms related to the increased effects of colchicine, like nausea, vomiting, numbness or tingling in your hands and legs, muscle pain, or weakness, contact your doctor immediately. Do not discontinue any medication without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as vegetables and fruit as it helps to boost your immune system. Try to take lean protein and whole grains.
  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.
  • Eat bland and low-fat foods, and avoid spicy or oily foods if you experience nausea or vomiting.
  • Practise safe sex by using condoms; it helps in reducing contact with semen and vaginal fluids.
  • Never share personal items with body fluids or blood on them, such as razor blades or toothbrushes.
  • Avoid sharing used needles, other injection or drug equipment.
  • Get tested for other sexually transmitted infections, such as gonorrhoea or syphilis.
  • Try to reduce emotional and physical stress by spending time with your family or doing whatever makes you happy.
  • Drink more fluids and avoid alcoholic beverages to prevent dehydration. 

Habit Forming

No

Therapeutic Class

ANTIVIRALS

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Atavir 300mg Capsule contains Atazanavir, which belongs to the class of protease inhibitors. It works by inhibiting the protease enzyme production, which is required for the HIV-infected cells to make new viruses. This causes inhibition of viral replication.

No, completing the entire treatment course prescribed by the doctor is always recommended. Sudden discontinuation of the medicine can lead to serious side effects. Your doctor will decide whether to stop the medication or not.

Atavir 300mg Capsule doesn’t cure HIV infection. However, it helps to control the disease and prevent opportunistic infections.

Drug-Drug Interactions Checker List

  • PRAZOSIN
  • ALFUZOSIN
  • CISAPRIDE
  • ESTRADIOL
  • CYCLOSPORIN
  • TACROLIMUS
  • CLARITHROMYCIN

Special Advise

  • Get an HIV test done at least every three months.
  • Regular kidney and liver function and bone mineral density tests while taking Atavir 300mg Capsule are advised. 
  • Regularly get blood and urine tests done while taking Atavir 300mg Capsule.
  • Atavir 300mg Capsule may still develop infections or other illnesses associated with HIV infection or AIDS. So, people taking Atavir 300mg Capsule should be carefully monitored throughout the treatment.

Disease/Condition Glossary

HIV Infection: Human Immunodeficiency Virus (HIV) is a retroviral infection that attacks and damages the cells of the immune system. This weakens the ability to fight against infections and diseases. If this condition is left untreated, it can lead to Acquired Immuno Deficiency Virus (AIDS). Symptoms of HIV include headache, fever, chills, joint pain, fatigue, swollen lymph nodes, sore throat, mouth nodes, muscle aches, etc. Atavir 300mg Capsule helps reduce the symptoms, control the infection, and also helps improve the HIV patient’s quality of life.

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