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  3. Axitaxel 100 mg Injection 16.7 ml

Axitaxel 100 mg Injection 16.7 ml, Pack of 1 INJECTION
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Composition :

PACLITAXEL-100MG/16.7ML

Manufacturer/Marketer :

Axiommax Oncology Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Axitaxel 100 mg Injection 16.7 ml

Axitaxel 100 mg Injection 16.7 ml belongs to the group of anti-cancer medicines called anti-microtubule agents used to treat various types of cancers, including ovarian and breast cancer (in advanced/spreading state or after surgery) and advanced-stage non-small cell lung cancer. 
 
Axitaxel 100 mg Injection 16.7 ml contains ‘Paclitaxel’, which works by stopping cell division and preventing the growth of certain cancer cells. 
 
In some cases, Axitaxel 100 mg Injection 16.7 ml may cause common side effects, such as nausea, vomiting, mild diarrhoea, and joint or muscle pain. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.
 
Consult your doctor if you are pregnant, breastfeeding, think you may be pregnant or are planning pregnancy. Axitaxel 100 mg Injection 16.7 ml is not recommended for children below 18 years. Inform your doctor about your health condition and medications to rule out any side effects.

Uses of Axitaxel 100 mg Injection 16.7 ml

Ovarian cancer, breast cancer, non-small cell lung cancer.

Directions for Use

Axitaxel 100 mg Injection 16.7 ml will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Axitaxel 100 mg Injection 16.7 ml belongs to the group of anti-cancer medicines called anti-microtubule agents used to treat various types of cancers, including ovarian and breast cancer (in advanced/spreading state or after surgery) and advanced-stage non-small cell lung cancer. It may also be used when other treatments have failed or in combination with other treatments. Axitaxel 100 mg Injection 16.7 ml may also be indicated in patients with Kaposi’s sarcoma (cancer that develops from the cells that line lymph or blood vessels) associated with AIDS (Acquired Immuno-Deficiency Syndrome), where other treatments have not been effective. Axitaxel 100 mg Injection 16.7 ml contains ‘Paclitaxel’, which works by preventing the growth of certain cancer cells. 

Storage

Store in a cool and dry place away from sunlight

Side Effects of Axitaxel 100 mg Injection 16.7 ml

  • Nausea
  • Vomiting
  • Diarrhoea
  • Hair loss
  • Joint or muscle pain
  • Decreased blood cell count

Drug Warnings

Do not take Axitaxel 100 mg Injection 16.7 ml if you are allergic to any of its components, if your white blood cell or platelet count is very low, if you have a serious uncontrolled infection, and Axitaxel 100 mg Injection 16.7 ml has to be given for the treatment of Kaposi’s sarcoma (cancer that causes lesions in soft tissues), or if you have severe liver problems. Inform your doctor if you have heart disease, abnormal blood cell counts, irregular heartbeat, tingling, numbness, or burning sensation in fingers or toes, visual problems, if you are on radiation therapy, or if you have Kaposi’s sarcoma and have a sore or inflamed mouth. Also, inform your doctor if you are pregnant, breastfeeding, think you are pregnant or planning pregnancy.

Drug-Drug Interactions

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PaclitaxelEtanercept
Severe
PaclitaxelBaricitinib
Severe

Drug-Drug Interactions

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PaclitaxelEtanercept
Severe
How does the drug interact with Axitaxel 100 mg Injection 16.7 ml:
When Etanercept is used with Axitaxel 100 mg Injection 16.7 ml, the likelihood or severity of infection may increase.

How to manage the interaction:
Although there is a possible interaction between Etanercept and Axitaxel 100 mg Injection 16.7 ml, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
PaclitaxelBaricitinib
Severe
How does the drug interact with Axitaxel 100 mg Injection 16.7 ml:
Coadministration of baricitinib and Axitaxel 100 mg Injection 16.7 ml can raise the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Axitaxel 100 mg Injection 16.7 ml if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
PaclitaxelClozapine
Severe
How does the drug interact with Axitaxel 100 mg Injection 16.7 ml:
Combining Axitaxel 100 mg Injection 16.7 ml with Clozapine can increase the risk of infection.

How to manage the interaction:
Taking Axitaxel 100 mg Injection 16.7 ml with Clozapine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to your doctor.
PaclitaxelRitonavir
Severe
How does the drug interact with Axitaxel 100 mg Injection 16.7 ml:
Taking Ritonavir and Axitaxel 100 mg Injection 16.7 ml may significantly increase the blood levels of Axitaxel 100 mg Injection 16.7 ml.

How to manage the interaction:
Taking Ritonavir with Axitaxel 100 mg Injection 16.7 ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. In case of any unusual symptoms, consult a doctor. Do not stop using any medications without talking to a doctor.
PaclitaxelThalidomide
Severe
How does the drug interact with Axitaxel 100 mg Injection 16.7 ml:
Taking thalidomide together with Axitaxel 100 mg Injection 16.7 ml may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Axitaxel 100 mg Injection 16.7 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
PaclitaxelInfliximab
Severe
How does the drug interact with Axitaxel 100 mg Injection 16.7 ml:
Combining Infliximab with Axitaxel 100 mg Injection 16.7 ml can enhance the breakdown of Axitaxel 100 mg Injection 16.7 ml in the body. This can reduce the treatment outcomes and can increase the risk or severity of developing serious infections.

How to manage the interaction:
Taking Axitaxel 100 mg Injection 16.7 ml with Infliximab together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PaclitaxelTofacitinib
Severe
How does the drug interact with Axitaxel 100 mg Injection 16.7 ml:
Taking Tofacitinib with Axitaxel 100 mg Injection 16.7 ml may increase the risk of infection.

How to manage the interaction:
Although taking Axitaxel 100 mg Injection 16.7 ml and Tofacitinib together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
PaclitaxelCladribine
Severe
How does the drug interact with Axitaxel 100 mg Injection 16.7 ml:
Combining Cladribine with Axitaxel 100 mg Injection 16.7 ml can increase the risk of developing serious infections.

How to manage the interaction:
Taking Axitaxel 100 mg Injection 16.7 ml with Cladribine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs and spices in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Author Details

Doctor imageDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Doctor imageDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 20, 2024 | 1:16 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Axitaxel 100 mg Injection 16.7 ml works by stopping cell division and preventing the growth of certain cancer cells.

Axitaxel 100 mg Injection 16.7 ml might cause sterility which could be permanent. Please talk to your doctor if you have any concerns.

The most common side effect of Axitaxel 100 mg Injection 16.7 ml is hair loss. The hair may grow back after the treatment with Axitaxel 100 mg Injection 16.7 ml is finished. However, consult your doctor if you have any concerns.

Drug-Drug Interactions Checker List

  • RIFAMPICIN
  • ERYTHROMYCIN
  • KETOCONAZOLE
  • FLUOXETINE
  • CARBAMAZEPINE
  • PHENYTOIN
  • GEMFIBROZIL
  • CIMETIDINE
  • RITONAVIR
  • SAQUINAVIR
  • INDINAVIR
  • NELFINAVIR
  • EFAVIRENZ
  • NEVIRAPINE
  • CLOPIDOGREL

Special Advise

  • Your doctor may advise regular blood tests to check for liver activity, kidney function and blood cell count.
  • You and/or your partner should use reliable contraception during treatment with Axitaxel 100 mg Injection 16.7 ml and for at least six months after the treatment.

Disease/Condition Glossary

Breast cancer: It is a type of cancer that develops in the breast when the breast cells begin to grow abnormally. Symptoms of breast cancer include a lump in the breast or tissue thickening which feels different than the normal surrounding tissues, breast pain, redness, swelling, nipple discharge other than breast milk, bloody discharge, unexplained change in shape, size or appearance of the breast, peeling, flaking or scaling of the skin, and a lump or swelling under the arm.

Ovarian Cancer: Ovarian cancer occurs when abnormal cells grow and multiply in the ovaries and fallopian tubes. Signs and symptoms include pain, swelling, or a feeling of pressure in the pelvis or abdomen, frequent or sudden urge to urinate, feeling full or trouble eating, a lump in the pelvic area, gas, bloating, or constipation.

Non-small cell lung cancer: It is a disease in which cancer cells form in the tissues of the lungs. Smoking is the major risk factor for non-small cell lung cancer. Symptoms include a cough that does not go away and shortness of breath.

Side effects of Axitaxel 100 mg Injection 16.7 ml
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
  • Eat protein-rich foods like fish, poultry, eggs, and legumes.
  • Include foods with minerals and vitamins essential for hair health.
  • Join a support group to connect with others experiencing hair loss.
  • Openly discuss your feelings about hair loss.
  • Consider covering up with wigs, hats, or scarves.
  • Be patient and avoid seeking miracle cures.
  • If you experience symptoms such as mouth ulcers, redness, difficulty in swallowing or talking, abdominal pain, and painful bowel movements as a drug side effect, consult your doctor as they may adjust the dose if necessary or prescribe alternative medication.
  • Practice good hygiene, such as washing your hands regularly, to prevent infection.
  • Drink plenty of water to keep your mucous membranes hydrated and promote healing.
  • Avoid spicy or acidic foods, which can irritate the mucous membranes and exacerbate inflammation.
  • Increase your intake of omega-3 fatty acids, found in fatty fish, nuts, and seeds, to reduce inflammation.
  • Follow a soft food diet to reduce discomfort and promote healing.
  • Eat well-cooked food to minimize infection risk.
  • Practice good hand hygiene to prevent infections.
  • Avoid crowds and people with illnesses to reduce exposure.
  • Wear a mask when necessary to lower infection risk.
  • Rest adequately to support your body's healing process.
  • Stay hydrated by drinking plenty of water.
  • Regularly monitor blood cell counts for changes.
  • Seek immediate medical help if symptoms like fever, chills, or fatigue occur.
  • Consult your doctor right away if concerning symptoms arise.
  • Follow your doctor's guidance on managing myelosuppression and infection prevention.
  • Your doctor may recommend regular liver function tests (LFT) to monitor liver enzyme levels.
  • To support your liver, eat a healthy diet with lots of fruits, vegetables, lean proteins, and healthy fats.
  • Avoid eating processed meats, sugary foods, and unhealthy fats.
  • Limit your alcohol consumption, since too much can worsen liver function and contribute to high levels of Alkaline Phosphatase (ALP).
  • Stay active with regular exercise, drink plenty of water, and try to avoid harmful chemicals that can damage your liver.
  • Quit smoking to lower the risk of elevated ALP levels.
  • Try taking pain relievers like paracetamol, ibuprofen or naproxen to releve discomfort and pain.
  • Avoid strenuous activities that worsen muscle and joint pain.
  • Do gentle stretching exercises to enhance muscle flexibility and reduce joint pain.
  • Apply cold or warm compresses to your joints and muscles for pain relief.
  • Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • If your joint/muscle pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
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