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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Hari Kumar , MBBS
Non returnable*
COD available

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Manufacturer/Marketer :

Johnson & Johnson Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Benadryl DR Syrup

Benadryl DR Syrup contains an anti-tussive (relieve cough) medication primarily used to treat dry cough. A cough is a reflex action that helps to clear any foreign irritant or mucus in the throat. 

Benadryl DR Syrup contains Dextromethorphan hydrobromide, a cough suppressant. It works by blocking the cough receptor present in the brain, which is known to cause cough.

The most common side effects of Benadryl DR Syrup are dizziness, drowsiness, sleepiness, confusion, and nausea. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are pregnant or breastfeeding, please inform your doctor before starting Benadryl DR Syrup. Benadryl DR Syrup should be given to children only if prescribed by the doctor. Benadryl DR Syrup may cause drowsiness, so drive with caution. Let your doctor know if you are taking any prescription/non-prescription drugs or herbal products before starting Benadryl DR Syrup.

Uses of Benadryl DR Syrup

Dry cough

Directions for Use

Tablet: Swallow it as a whole with water; do not crush, break or chew it.Syrup/Drops: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.Lozenges: Place the lozenge in the mouth and allow it to dissolve slowly. Do not crush, chew or swallow as a whole.

Medicinal Benefits

Benadryl DR Syrup is primarily used to treat dry cough. Benadryl DR Syrup contains Dextromethorphan hydrobromide, a cough suppressant. It works by blocking the cough receptor present in the brain, which is known to cause cough. Benadryl DR Syrup is generally prescribed for short-term treatment of dry cough. 

Storage

Store in a cool and dry place away from sunlight
Side effects of Benadryl DR Syrup, 50 ml
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.

Drug Warnings

Do not take Benadryl DR Syrup if you are allergic to any of the contents. If you are pregnant or breastfeeding, please inform your doctor before starting Benadryl DR Syrup. If your condition does not improve or you have a recurring cough with fever, rash, please visit the doctor immediately, as this could be serious. Benadryl DR Syrup should be taken at least 15 days after the last dose of anti-depressants, especially monoamine oxidase inhibitors (MAO), as taking both together may be fatal.

Drug-Drug Interactions

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DextromethorphanRasagiline
Critical
DextromethorphanProcarbazine
Critical

Drug-Drug Interactions

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DextromethorphanRasagiline
Critical
How does the drug interact with Benadryl DR Syrup, 50 ml:
Taking Rasagiline with Benadryl DR Syrup, 50 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Benadryl DR Syrup, 50 ml with Rasagiline is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, shaking, incoordination, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor. Do not discontinue any medications without consulting a doctor.
DextromethorphanProcarbazine
Critical
How does the drug interact with Benadryl DR Syrup, 50 ml:
Co-administration of Benadryl DR Syrup, 50 ml and Procarbazine may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Procarbazine with Benadryl DR Syrup, 50 ml can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, or diarrhea - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
DextromethorphanTranylcypromine
Critical
How does the drug interact with Benadryl DR Syrup, 50 ml:
Taking Tranylcypromine with Benadryl DR Syrup, 50 ml can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Benadryl DR Syrup, 50 ml with Tranylcypromine is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fit blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
DextromethorphanPhenelzine
Critical
How does the drug interact with Benadryl DR Syrup, 50 ml:
Co-administration of Phenelzine and Benadryl DR Syrup, 50 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Phenelzine and Benadryl DR Syrup, 50 ml can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DextromethorphanPargyline
Critical
How does the drug interact with Benadryl DR Syrup, 50 ml:
Co-administration of Pargyline and Benadryl DR Syrup, 50 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Benadryl DR Syrup, 50 ml and Pargyline can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DextromethorphanIsocarboxazid
Critical
How does the drug interact with Benadryl DR Syrup, 50 ml:
Co-administration of Isocarboxazid with Benadryl DR Syrup, 50 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Benadryl DR Syrup, 50 ml and Isocarboxazid can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DextromethorphanSelegiline
Critical
How does the drug interact with Benadryl DR Syrup, 50 ml:
Co-administration of Benadryl DR Syrup, 50 ml and Selegiline may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Selegiline with Benadryl DR Syrup, 50 ml can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, or diarrhea - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
DextromethorphanQuinidine
Severe
How does the drug interact with Benadryl DR Syrup, 50 ml:
Co-administration of Benadryl DR Syrup, 50 ml and Quinidine may increase the effects of Benadryl DR Syrup, 50 ml.

How to manage the interaction:
Although there is a possible interaction between Benadryl DR Syrup, 50 ml and Quinidine, you can take these medicines together if prescribed by a doctor. However, if you experience drowsiness, difficulty breathing, dizziness, restless feeling, anxiety, nervousness, confusion, or diarrhea, contact a doctor. Do not discontinue the medication without consulting a doctor.
DextromethorphanDolasetron
Severe
How does the drug interact with Benadryl DR Syrup, 50 ml:
Co-administration of Benadryl DR Syrup, 50 ml with Dolasetron can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Although there is a possible interaction between Benadryl DR Syrup, 50 ml and Dolasetron, you can take these medicines together if prescribed by a doctor. If you notice any of these signs - like feeling confused, having seizures, a fast heartbeat, fever, sweating a lot, shaking, blurry vision, muscle spasms, trouble moving, stomach pain, feeling sick, throwing up, or having diarrhea - it's a good idea to call a doctor right away. Do not stop using any medications without talking to a doctor.
DextromethorphanBuspirone
Severe
How does the drug interact with Benadryl DR Syrup, 50 ml:
Co-administration of Benadryl DR Syrup, 50 ml with Buspirone can increase the risk of serotonin syndrome. (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Buspirone along with Benadryl DR Syrup, 50 ml can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, incoordination, stomach pain, nausea, vomiting, and diarrhea, consult the doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Wash your hands with soap and water regularly to prevent the spread of germs.
  • Eat plenty of foods rich in good bacteria, like yoghurt, to improve overall health.
  • Drink plenty of fluids to avoid dehydration.
  • Gargle with salt water for relief from sore throat.
  • Do not smoke, as it might worsen your symptoms.
  • Avoid alcohol consumption as it may cause tiredness, drowsiness, or lack of concentration.

Habit Forming

No

Therapeutic Class

RESPIRATORY STIMULANTS

Benadryl DR Syrup Substitute

Substitutes safety advice
  • Benadryl DR Syrup, 100 ml

    by Others

    1.33per tablet
  • Biochemdryl DR Syrup 100 ml

    by Others

    1.25per tablet
  • Cofsils Dry Cough Syrup 100 ml

    by AYUR

    0.94per tablet
  • Suntuss DR Sugar Free Menthol-Lemon Flavour Syrup 100 ml

    by Others

    0.68per tablet
  • Biochemdryl DR 15mg Syrup

    by Others

    1.38per tablet

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Benadryl DR Syrup works by blocking the cough receptor present in the brain, which is known to cause cough.

To treat your condition effectually, continue taking Benadryl DR Syrup for as long as your doctor has prescribed. Do not be reluctant to speak with your doctor if your condition does not improve or if you experience any difficulty whilst taking Benadryl DR Syrup.

Benadryl DR Syrup may cause drowsiness. So operating any machinery or driving a car, doing an activity that requires concentration and alertness should be avoided unless you are alert.

Take Benadryl DR Syrup only as prescribed. Benadryl DR Syrup can have addictive effects if taken in more than the recommended dose.

It is not recommended to take Benadryl DR Syrup along with any anti-depressant medication as it can lead to unpleasant side effects or drug interaction. Also, Benadryl DR Syrup should be taken at least 15 days after your last dose of anti-depressants, especially monoamine oxidase inhibitors (MAO).

Drug-Drug Interactions Checker List

  • ISOCARBOXAZID
  • PHENELZINE
  • RASAGILINE
  • SELEGILINE
  • TRANYLCYPROMINE
  • AMIODARONE
  • PROPAFENONE
  • QUINIDINE
  • FLECAINIDE
  • CODEINE
  • TRAMADOL
  • MORPHINE
  • METHADONE
  • FLUOXETINE
  • PAROXETINE
  • SERTRALINE
  • TERBINAFINE

Special Advise

  • Do not use dextromethorphan if you have used an MAO inhibitor within the past 14 days. (isocarboxazid, phenelzine, rasagiline, selegiline, tranylcypromine or methylene blue injection).

Disease/Condition Glossary

Dry cough: It is a reflex action that helps to clear any foreign irritant or mucus in the throat. Mostly cough lasts for a short time (two to three weeks), so it is acute. But sometimes, if it is persistent for more than eight weeks, it can lead to chronic cough. The most common causes of cough are cold/flu, asthma, emphysema, and COPD (chronic obstructive pulmonary disease). 

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