Pentazocine
About
Pentazocine belongs to a group of medicines called opiates/narcotic analgesics used to relieve moderate to severe pain. It is indicated in the management of pain severe enough to require an opioid analgesic for which alternative treatment is inadequate. It is also used as a pre-anaesthetic or pre-operative medication and as a supplement to surgical anaesthesia.
Pentazocine contains ‘Pentazocine’, which works by changing the way the nervous system and brain respond to pain. Thereby, Pentazocine helps provide relief from pain.
In some cases, Pentazocine may cause common side effects such as nausea, vomiting, dizziness or lightheadedness and euphoria. You are advised to talk to your doctor if the side effects persist or worsen.
Consult your doctor if you are pregnant or breastfeeding. Avoid driving or operating machinery as Pentazocine may impair the physical and mental ability. Keep your doctor informed about your health condition and medicines to rule out any side effects/interactions.
Uses of Pentazocine
Medicinal Benefits
Pentazocine belongs to a group of medicines called opiates/narcotic analgesics used to relieve moderate to severe pain. It is indicated in the management of pain severe enough to require an opioid analgesic for which alternative treatment is inadequate. It is also used as a pre-anaesthetic or pre-operative medication and as a supplement to surgical anaesthesia. Pentazocine contains ‘Pentazocine’, which works by changing the way the nervous system and brain respond to pain. Thereby, Pentazocine helps provide relief from pain.
Directions for Use
Storage
Side Effects of Pentazocine
- Nausea
- Vomiting
- Dizziness or lightheadedness
- Euphoria (a feeling of intense happiness or excitement)
In-Depth Precautions and Warning
Drug Warnings
Do not take Pentazocine if you are allergic to any of its components; if you have significant respiratory depression, acute or severe bronchial asthma in the absence of resuscitative equipment or in an unmonitored setting, gastrointestinal obstruction, including paralytic ileus. Inform your doctor if you have/had liver or kidney problems, adrenal insufficiency, severe hypotension, seizures, myocardial infarction, or biliary surgery. Consult your doctor if you are pregnant or breastfeeding. Concomitant use of opioids with benzodiazepines, and other central nervous system agents, including alcohol, might result in profound sedation, respiratory depression, coma, and death. Pentazocine may cause serious respiratory depression; hence monitoring is advised.
Drug Interactions
Drug-Drug Interactions: Inform your doctor if you are taking benzodiazepines, central nervous system agents, serotonergic drugs, mixed agonists/antagonists, partial agonist opioid analgesics, muscle relaxants, diuretics, or anticholinergic drugs.
Drug-Food Interactions: No interactions found/established.
Drug-Disease Interactions: Inform your doctor if you have respiratory depression, bronchial asthma, or gastrointestinal obstruction.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid the consumption of alcohol, as it may cause profound sedation.
Pregnancy
cautionIf you are pregnant or planning pregnancy, inform your doctor before receiving Pentazocine. Prolonged use of Pentazocine in pregnancy may cause neonatal opioid withdrawal syndrome.
Breast Feeding
cautionIf you are breastfeeding, inform your doctor before receiving Pentazocine. Your doctor may prescribe this medicine if the benefits outweigh the risks. Infants exposed to Pentazocine through breast milk should be monitored for excessive sedation and respiratory depression. Withdrawal symptoms can develop in breastfed babies when maternal administration of an opioid painkiller is stopped or when nursing is terminated.
Driving
unsafePentazocine may alter your physical and mental ability. Therefore, avoid driving or operating machinery.
Liver
cautionIf you have a history of liver disease, inform your doctor before receiving Pentazocine. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Kidney
cautionIf you have a history of kidney diseases, inform your doctor before receiving Pentazocine. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Children
cautionPentazocine is not recommended for use in children under one year. The doctor will decide the dose of this medicine based on the age, body weight and clinical condition of your child.
Habit Forming
Diet & Lifestyle Advise
- Include fresh fruits and vegetables in your diet.
- Rest and sleep well.
- Stay hydrated, and drink plenty of water.
- Eat anti-inflammatory foods.
Patients Concern
Disease/Condition Glossary
Pain: Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain can be generalized (overall body aches) or localized (affecting a specific area of the body). The common causes of pain include headache, muscle strain, cramps, fractures, arthritis, and injury.
FAQs
Pentazocine works by changing the way the nervous system and brain respond to pain.
Pentazocine may cause respiratory depression. Monitoring for respiratory depression during the initiation of treatment or following a dose increase is advised.
It is contraindicated for use in patients with known or suspected gastrointestinal obstruction, including paralytic ileus. Consult your doctor if you have any concerns.