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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Hari Kumar , MBBS
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Manufacturer/Marketer :

Tregenesis Sciences Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Benztre-L Capsule 10's

Benztre-L Capsule 10's belongs to a group of medicines called gastrointestinal agents used to treat gastro-oesophageal reflux disease (GERD), acidity, heartburn, Zollinger-Ellison syndrome, Helicobacter pylori infection, irritable bowel syndrome, indigestion, duodenal and gastric ulcers. The stomach is usually protected from acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to acidity. 
 
Benztre-L Capsule 10's is a combination of two drugs, namely: Rabeprazole (proton pump inhibitor) and Levosulpiride (prokinetic agent). Rabeprazole works by blocking an enzyme called the gastric proton pump, which is responsible for acid production. Levosulpiride works by increasing the pressure of the inferior oesophageal (food pipe) sphincter, thereby preventing the backflow of food and acid into the mouth. Together, Benztre-L Capsule 10's helps in preventing acid reflux, thereby providing relief from acidity and heartburn.
 
You are advised to take Benztre-L Capsule 10's for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as headache, nausea, vomiting, gas, abdominal pain, dizziness, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Inform your doctor if you have a history of gastrointestinal bleeding or intestinal obstruction. On long-term treatment, Benztre-L Capsule 10's may cause osteoporosis and hypomagnesemia. Consult a doctor if you are pregnant or breastfeeding. Benztre-L Capsule 10's may cause drowsiness and dizziness, so drive only if you are alert. Benztre-L Capsule 10's is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol along with Benztre-L Capsule 10's as it could lead to increased drowsiness and elevate stomach acid production. 

Uses of Benztre-L Capsule 10's

Gastro-oesophageal reflux disease, acidity, indigestion heartburn, and peptic ulcers.

Directions for Use

Take Benztre-L Capsule 10's 1hour prior to food. Swallow Benztre-L Capsule 10's as a whole with a glass of water; do not chew or crush it.

Medicinal Benefits

Benztre-L Capsule 10's is a combination of two drugs, namely: Rabeprazole and Levosulpiride. Benztre-L Capsule 10's belongs to a group of medicines called gastrointestinal agents used to treat gastro-oesophageal reflux disease (GERD), acidity, heartburn, Zollinger-Ellison syndrome, Helicobacter pylori infection, irritable bowel syndrome, indigestion, duodenal and gastric ulcers. Rabeprazole is a proton pump inhibitor that works by blocking an enzyme called gastric proton pump, which is responsible for the production of acid. Levosulpiride is a prokinetic agent that increases the pressure of the inferior oesophageal (food pipe) sphincter, thereby preventing the backflow of food and acid into the mouth. Together, Benztre-L Capsule 10's helps in preventing acid reflux, thereby providing relief from acidity and heartburn. 

Storage

Keep Benztre-L Capsule 10's out of reach and sight of children.
Side effects of Benztre-L Capsule
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

Drug Warnings

Do not take Benztre-L Capsule 10's if you are allergic to any of its components. Inform your doctor if you have a history of pheochromocytoma (tumour of the adrenal gland), epilepsy, mania, gastrointestinal bleeding, intestinal obstruction, or severe kidney or liver impairment. Benztre-L Capsule 10's may cause osteoporosis (weak and brittle bones) and hypomagnesemia (low magnesium levels) on long-term treatment. Consult a doctor if you are pregnant or breastfeeding. Benztre-L Capsule 10's may cause dizziness and drowsiness, so drive only if you are alert. Benztre-L Capsule 10's is not recommended for children as safety and effectiveness have not been established.

Drug-Drug Interactions

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RabeprazoleRilpivirine
Critical

Drug-Drug Interactions

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How does the drug interact with Benztre-L Capsule:
When used in combination with erlotinib, Benztre-L Capsule may prevent the absorption of erlotinib into the circulation, which might make erlotinib less effective in treating cancer.

How to manage the interaction:
Taking Benztre-L Capsule with Erlotinib is not recommended as it can result in an interaction, it should be taken only if a doctor has advised it. Do not stop using any medications without consulting a doctor.
RabeprazoleRilpivirine
Critical
How does the drug interact with Benztre-L Capsule:
Co-administration of Benztre-L Capsule can make Rilpivirine less effective by reducing its absorption in the body.

How to manage the interaction:
Taking Benztre-L Capsule with Rilpivirine is not recommended, but can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Benztre-L Capsule:
When Phenytoin and Benztre-L Capsule are taken in combination, Phenytoin will reduce the concentration or impact of Benztre-L Capsule.

How to manage the interaction:
Although taking Phenytoin and Benztre-L Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Benztre-L Capsule:
Taking Benztre-L Capsule together with Acalabrutinib results in a decreased effectiveness of Acalabrutinib.

How to manage the interaction:
Although taking Benztre-L Capsule and Acalabrutinib together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Benztre-L Capsule:
Taking Benztre-L Capsule together with Gefitinib results in decreased levels of gefitinib in your blood. This can result in a decreased effectiveness of gefitinib in treating the disease.

How to manage the interaction:
Although taking Benztre-L Capsule and Gefitinib together can possibly result in an interaction, it can be taken if your doctor has prescribed it. To lessen the effects of the interaction, it is advised that you take gefitinib 12 hours before or 12 hours after Benztre-L Capsule. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Benztre-L Capsule:
Taking Benztre-L Capsule together with Dasatinib results in decreased levels of Dasatinib and its effectiveness.

How to manage the interaction:
Although taking Benztre-L Capsule and Dasatinib together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Benztre-L Capsule:
Co-administration of Atazanavir's blood levels and absorption can both be affected by Benztre-L Capsule, which decreases the atazanavir's ability to treat HIV.

How to manage the interaction:
Although taking Benztre-L Capsule and atazanavir together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
RabeprazoleIdelalisib
Severe
How does the drug interact with Benztre-L Capsule:
When Benztre-L Capsule and Idelalisib are taken in combination, Idelalisib may increase the level or impact of Benztre-L Capsule.

How to manage the interaction:
Although taking Benztre-L Capsule and Idelalisib together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Benztre-L Capsule:
Co-administration of Methotrexate with Benztre-L Capsule can increase the blood levels and side effects of Methotrexate.

How to manage the interaction:
Although there is a possible interaction between Benztre-L Capsule and Methotrexate, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with Benztre-L Capsule:
Taking Clopidogrel with Benztre-L Capsule can reduce the effectiveness of Clopidogrel.

How to manage the interaction:
Taking Clopidogrel and Benztre-L Capsule together possibly has an interaction, but you can take these medications together if a doctor has advised it. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increases acidity and heartburn.
  • Maintain a healthy weight by regular exercising.
  • Avoid lying down after eating to prevent acid reflux.
  • Avoid tight-fitting clothes as it might increase the pressure on the abdomen leading to acid reflux.
  • Practice relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea, and soda. 
  • Avoid sitting continuously as it may trigger acidity. Take a break of 5 minutes every hour by doing brisk walking or stretching.

Side Effects of Benztre-L Capsule 10's

  • Headache
  • Nausea
  • Vomiting
  • Flatulence
  • Abdominal pain
  • Dizziness
  • Diarrhoea 

Habit Forming

No

Therapeutic Class

ANTACIDS, ANTIULCERANTS

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Benztre-L Capsule 10's contains Rabeprazole and Levosulpiride. Rabeprazole works by blocking an enzyme called gastric proton pump, which is responsible for the production of acid. Levosulpiride works by increasing the pressure of the inferior oesophageal (food pipe) sphincter, thereby prevents the backflow of food and acid into the mouth. Together, Benztre-L Capsule 10's helps in providing relief from acidity.

Avoid lying down immediately after meals to prevent acid reflux. Raise the head of the bed 10-20cm by putting on a pillow so that the head and chest are above the waist. This helps in preventing acid reflux.

Benztre-L Capsule 10's contains rabeprazole which might increase the risk of osteoporosis (weak and brittle bones). This mainly occurs in people taking higher doses of Benztre-L Capsule 10's for longer durations. Inform your doctor if you are at risk of osteoporosis. Your doctor may prescribe calcium and vitamin D supplements.

Dry mouth could be a side-effect of Benztre-L Capsule 10's. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help stimulate saliva and thereby prevent drying of the mouth.

Do not take Benztre-L Capsule 10's for longer durations unless prescribed by the doctor. Benztre-L Capsule 10's might cause bone problems and hypomagnesemia on long-term treatment. Talk to your doctor if you do not find symptomatic relief despite taking Benztre-L Capsule 10's for 2 weeks.

Benztre-L Capsule 10's might cause irregular periods/abnormal menstruation. Consult your doctor if you notice abnormal bleeding patterns.

Drug-Drug Interactions Checker List

  • WARFARIN
  • METHOTREXATE
  • DIGOXIN
  • MYCOPHENOLATE MOFETIL
  • TACROLIMUS
  • AMOXICILLIN
  • CLARITHROMYCIN

Special Advise

  • Benztre-L Capsule 10's might cause false-positive results for secretin stimulation test, prolactin test, and tests for tetrahydrocannabinol (THC). Inform the person doing the tests that you are taking Benztre-L Capsule 10's.
  • Regular blood tests for monitoring magnesium levels and bone density tests are advised if you are on long-term treatment with Benztre-L Capsule 10's.
  • Inform your doctor if you are due to have Chromogranin A test.

Disease/Condition Glossary

Acidity: The stomach is usually protected from acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to complications like GERD, acidity, heartburn, and peptic ulcers.

Gastroesophageal reflux disease (GERD): It occurs when stomach acid frequently flows into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn and acidity. Symptoms include heartburn, sour or bitter taste in the mouth, and difficulty swallowing. 

Stomach ulcers: Stomach ulcers are sores that develop on the stomach and intestine lining due to erosion of the protective stomach lining. Symptoms include nausea, changes in appetite, bloody or dark stools, unexplained weight loss, vomiting, and indigestion. 

Indigestion: Indigestion is the feeling of fullness. It occurs due to slow gastric emptying. Symptoms include stomach pain, bloating, heartburn, nausea, and vomiting.

Have a query?

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Benztre-L Capsule 10's. Alcohol intake leads to increased production of stomach acid, thereby increases acidity and heartburn.

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Pregnancy

Caution

Consult your doctor if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Benztre-L Capsule 10's may pass into breast milk. Consult your doctor if you are breastfeeding; your doctor will decide whether Benztre-L Capsule 10's can be taken by breastfeeding mothers or not.

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Driving

Caution

Benztre-L Capsule 10's may cause dizziness and drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed. Consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Benztre-L Capsule 10's should not be given to children as the safety and effectiveness were not established.

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