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Written By aquibnaseer ,
Reviewed By Sunny S , MBBS
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Manufacturer/Marketer :

German Remedies Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Biodib-M 15 Tablet

Biodib-M 15 Tablet is a combination drug consisting of Pioglitazone (Thiazolidinediones), and Metformin (Biguanides) which are called anti-diabetic drugs & used to lower blood sugar levels in diabetic patients. Type 2 diabetes mellitus used to be known as 'non-insulin-dependent diabetes mellitus (NIDDM)' or 'maturity-onset diabetes'. Type 2 diabetes develops if the body does not produce enough insulin, or where the insulin that your body makes does not work as well as it should. It can also develop if the body produces too much glucagon. Insulin is a substance that helps to lower the level of sugar in your blood, especially after meals.

Biodib-M 15 Tablet is a blood sugar-lowering drug which contains a combination of Pioglitazone belonging to the class of thiazolidinediones & Metformin belonging to the class of biguanides. Pioglitazone decreases blood sugar and reverses the effects of Type II diabetes by activating switches (PPAR) inside cells to take up free glucose from blood and decrease its levels in blood. Metformin on the other hand decreases blood sugar by decreasing its formation and increasing its consumption by cells thereby decreasing high blood sugar levels. Biodib-M 15 Tablet is used in adults to treat type 2 (non-insulin dependent) diabetes mellitus when treatment with metformin alone is not sufficient.

Biodib-M 15 Tablet should be taken with food to avoid an upset stomach. Biodib-M 15 Tablet should be taken at the same time of the day each time for best results. For better advice, your doctor will decide, what dose should be taken and it can change timely depending upon your condition. Some people may stomach ache, feeling sick (Nausea), vomiting, diarrhoea, loss of appetite, localized swelling (oedema), weight gain, headache, respiratory infection, numbness, taste disturbance etc  . Most of these side effects of Biodib-M 15 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Biodib-M 15 Tablet should not be stopped even if you feel better, without consulting your doctor as sugar level keeps changing. If you stop taking Biodib-M 15 Tablet abruptly, it may increase your sugar levels which could further increase the risk of eyesight loss (retinopathy), kidney (nephropathy) and nerve damage (neuropathy). Biodib-M 15 Tablet should not be taken if you have type 1 diabetes mellitus, severe kidney or liver disease. Please inform your doctor if you have any heart disease, is or planning to get pregnant or breastfeeding.

Uses of Biodib-M 15 Tablet

Type II diabetes (Non insulin-dependent diabetes).

Directions for Use

Swallow Biodib-M 15 Tablet as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Biodib-M 15 Tablet lowers blood sugar in type II diabetic patients (Non insulin dependent ) & prevents diseases of the heart, kidneys, eyes & blood vessels in feet, which happens due to persistently high levels of blood sugar in diabetic patients. Biodib-M 15 Tablet plays a vital role in controlling blood sugar levels and prevents serious complications of diabetes like eyesight loss (retinopathy), kidney (nephropathy), nerve damage (neuropathy), diabetic foot ulcer and delayed wound healing. Biodib-M 15 Tablet lowers blood sugar due to activation of cell switches (PPAR) to take up free glucose from blood & use it for energy production (Pioglitazones)  & decrease production of glucose inside liver (Metformin) .

Storage

Keep Biodib-M 15 Tablet out of reach and sight of children.
Side effects of Biodib-M 15 Tablet
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Wear compression garments like stockings, sleeves, or gloves to apply pressure and help stop fluid from building up, especially after the swelling goes down.
  • Move around and do exercises to help the fluid circulate, especially in swollen limbs. Ask your doctor for specific exercises.
  • Raise the swollen area above your heart level several times a day, even while sleeping, to help reduce swelling.
  • Gently massage the swollen area with firm but not painful pressure.
  • Keep the swollen area clean and moisturized to prevent injury and infection.
  • Reduce salt intake to help prevent fluid from building up and worsening the swelling, as advised by a doctor.
  • If the swelling does not get better after a few days of home treatment or worsens, consult your doctor right away.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Drug Warnings

Biodib-M 15 Tablet should not be used in patients with type 1 diabetes or with diabetic ketoacidosis. Some diabetic patients, while taking Biodib-M 15 Tablet , might develop a rare but serious condition called lactic acidosis. In this condition, there is too much lactic acid accumulated in the blood that can damage the working of your liver and kidney required for the elimination of excess lactic acid from the blood. Before you start taking Biodib-M 15 Tablet , tell your doctor if you’ve ever had pancreatitis (inflammation of the pancreas), kidney disease, and low vitamin B12 level. Biodib-M 15 Tablet , when used with insulin, may extremely lower the blood sugar level leading to hypoglycemia condition, which can be fatal. In this case, your doctor may adjust the dose by lowering the dose of insulin or Biodib-M 15 Tablet . Prolonged intake of Biodib-M 15 Tablet may lower your thyroid-stimulating hormone (TSH); hence, an annual check-up of TSH is recommended. In rare cases, you may also develop a serious skin reaction known as bullous pemphigoid that requires immediate medical attention. Tell your doctor if you are going to have a diagnostic test with an injection of dye or X-ray contrast agent. The use of Biodib-M 15 Tablet should be stopped for a short time before having an X-ray procedure.

Drug-Drug Interactions

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MetforminMetrizamide
Critical
MetforminIopanoic acid
Critical

Drug-Drug Interactions

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MetforminMetrizamide
Critical
How does the drug interact with Biodib-M 15 Tablet:
Co-administration of Biodib-M 15 Tablet with Metrizamide together can cause the risk of lactic acidosis (when the body produces too much lactic acid ).

How to manage the interaction:
Taking Biodib-M 15 Tablet with Metrizamide is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience headaches, muscle cramps or pain, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetforminIopanoic acid
Critical
How does the drug interact with Biodib-M 15 Tablet:
Co-administration of Iopanoic acid with Biodib-M 15 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Biodib-M 15 Tablet with Iopanoic acid is not recommended, please consult your doctor before taking it.
MetforminIodamide
Critical
How does the drug interact with Biodib-M 15 Tablet:
Co-administration of Biodib-M 15 Tablet and Iodamide can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Biodib-M 15 Tablet with Iodamide is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIoglicic acid
Critical
How does the drug interact with Biodib-M 15 Tablet:
Co-administration of Ioglicic acid with Biodib-M 15 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Biodib-M 15 Tablet with Ioglicic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIoversol
Critical
How does the drug interact with Biodib-M 15 Tablet:
Co-administration of Ioversol with Biodib-M 15 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Biodib-M 15 Tablet with Ioversol is not recommended, please consult your doctor before taking it.
MetforminIocetamic acid
Critical
How does the drug interact with Biodib-M 15 Tablet:
Co-administration of Biodib-M 15 Tablet and Iocetamic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Biodib-M 15 Tablet with Iocetamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIopromide
Critical
How does the drug interact with Biodib-M 15 Tablet:
Co-administration of Iopromide with Biodib-M 15 Tablet can increase the risk of lactic acidosis.

How to manage the interaction:
Taking Iopromide with Biodib-M 15 Tablet is not recommended, please consult a doctor before taking it. Do not discontinue the medication without consulting a doctor.
MetforminIoglycamic acid
Critical
How does the drug interact with Biodib-M 15 Tablet:
Co-administration of Ioglycamic acid with Biodib-M 15 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Biodib-M 15 Tablet with Ioglycamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIomeprol
Critical
How does the drug interact with Biodib-M 15 Tablet:
Co-administration of Iomeprol with Biodib-M 15 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Biodib-M 15 Tablet with Iomeprol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIopentol
Critical
How does the drug interact with Biodib-M 15 Tablet:
Co-administration of Iopentol with Biodib-M 15 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Biodib-M 15 Tablet with Iopentol is not recommended, please consult your doctor before taking it.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Fill your half plate with starchy veggies, a quarter with proteins, and a quarter with whole grain.
  • Eat at regular intervals. Do not take a long gap between a meal or snack.
  • Monitor your blood sugar level regularly especially when there are lots of fluctuations.
  • Invest at least 150 min of moderate-intensity physical activity or one hour and 15 minutes of high-intensity exercise every week.
  • Lose weight gradually to achieve a healthy body mass index (18.5 to 24.9).
  • Replace refined carbohydrates containing foods with whole grain foods and increase the intake of fruits and veggies and other fibre-enriched foods.
  • Reduce intake of saturated fat (or hidden fats) in food like chips, crisps, pastries, biscuits, and samosas. Choose omega 3 fatty acid-containing oils for daily cooking. For frying, you can use palm oil, mustard oil, groundnut oil, rice bran oil, and safflower oil.
  • Do not take stress as it may elevate your blood sugar level. You can adopt stress management techniques like mindfulness to control stress-related blood sugar changes.
  • Opt for low-fat dairy products (low-fat yoghurt, fat-free milk, and cheese, etc.).
  • Keep your blood pressure as normal (140/90) as possible. As it reduces the risk of cardiovascular diseases in diabetes patients.

Side Effects of Biodib-M 15 Tablet

  • Diarrhoea
  • Loss of appetite
  • Headache
  • Nausea
  • Vomiting

Habit Forming

No

Therapeutic Class

ANTIDIABETICS AND ANTIHYPERGLYCEMICS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Biodib-M 15 Tablet can cause fluid retention which cause heart failure.The doctor usually recommends to start from a lower dose and increase the dose, slowly while treating patients who are at risk of heart failure. Heart failure is reported mainly in patients taking insulin & Biodib-M 15 Tablet simultaneously.

There has been rare cases of liver damage in patients taking Biodib-M 15 Tablet . The doctor usually screens the patient continuously during the course of treatment with Biodib-M 15 Tablet . A patient is advised to visit doctor strictly as per what doctor has advised.

Biodib-M 15 Tablet is contradictory to be used in patients with high blood pressure. Doctors consultation is required before taking this drug in a patient with high blood pressure.

Biodib-M 15 Tablet is safe to be taken before driving a vehicle or operating machinery as far as blood sugar levels are stable. A patient is advised to take proper precautions and make sure that Biodib-M 15 Tablet is not taken with another blood sugar lowering agent.

Not recommended to be taken with contraceptives. Biodib-M 15 Tablet decreases the activity of oral contraceptives like Ethinyl estradiol by almost 30% and leads to failure of contraception.

Drug-Drug Interactions Checker List

  • GEMFIBROZIL
  • RIFAMPICIN
  • CIMETIDINE
  • DEFLAZACORT
  • SPIRONOLACTONE
  • IBUPROFEN
  • CELECOXIB
  • CAPTOPRIL
  • TELMISARTAN

Special Advise

Contact your doctor immediately if you have  nausea, vomiting, kussmaul breathing  (laboured and deep), and generalised weakness which are symptoms of Lactic acidosis, a very rare but serious metabolic complication. 

Disease/Condition Glossary

Type 2 diabetes is a condition where the body is unable to make sufficient insulin, or the insulin that it makes doesn't work properly or utilized by our body. This can cause high blood sugar levels (hyperglycaemia). Symptoms of type 2 diabetes include increased thirst, frequent urination, slow , increased hunger, fatigue, and blurred vision. In some cases, there may be weight gain while in rare cases weight loss may be observed. The complication of type 2 diabetes also includes neuropathy (nerve problems), nephropathy (kidney problems), and retinopathy (damaged retina of eyes or blindness), loss of limbs, sexual dysfunction, and increase the chance of heart attack or stroke.

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Alcohol

Unsafe

Not recommended with alcohol as it may result in harmful decrease or increase in levels of blood sugar depends on how much alcohol a patient has consumed.

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Pregnancy

Caution

Not recommended in pregnancy. Biodib-M 15 Tablet treatment should be stopped and replaced with any other alternative drug from other blood sugar-lowering agents on recommendation of a doctor. You must tell your doctor if you are pregnant, think you may be pregnant or are planning to have a baby.

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Breast Feeding

Caution

Not recommended in breastfeeding mothers. Do not use Biodib-M 15 Tablet if you are breastfeeding or are planning to breast-feed as doctor's consultation is required.

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Driving

Safe if prescribed

Safe to use during driving or operating heavy machinery. This medicine will not affect your ability to drive or use machines but care is to be taken if you experience abnormal vision or anything that affects your ability to drive.

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Liver

Caution

Biodib-M 15 Tablet should be used with caution in patients with liver disease as Biodib-M 15 Tablet has been found to cause harmful interactions in them. Doctors recommendation is required before taking this drug.

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Kidney

Caution

Biodib-M 15 Tablet should be taken with caution in patients with kidney disease. In rare cases, serious interaction has been found in kidney patients called lactic acidosis thus doctors consultation is required before taking this drug.

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Children

Unsafe

Not recommended in children below 12 years of age. Use in children and adolescents under 18 years is not recommended. Consult a doctor for better alternatives blood sugar-lowering agents in diabetic children.

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