Biophenicol Succinate Injection 1gm

Written By Santoshini Reddy G , M Pharmacy

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

MRP ₹112

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₹16.8 Cashback (15%)

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Whats That

About Biophenicol Succinate Injection 1gm

Biophenicol Succinate Injection 1gm belongs to the group of medicines called antibiotics used to treat severe bacterial infections such as meningitis and typhoid. It should only be used when other antibiotics are not suitable. Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body. Biophenicol Succinate Injection 1gm does not work against infections caused by viruses, including colds and flu.

Biophenicol Succinate Injection 1gm contains ‘Chloramphenicol’ that works by preventing the synthesis of essential proteins which are necessary for vital bacterial functions. Thus, kills the bacteria and helps in treating infection. Biophenicol Succinate Injection 1gm is a broad-spectrum antibiotic which is active against both gram-positive and gram-negative bacteria.

In some cases, you may experience common side effects such as nausea, vomiting, diarrhoea, dry mouth and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.

Do not use Biophenicol Succinate Injection 1gm if you are pregnant or breastfeeding. Biophenicol Succinate Injection 1gm is safe for children if prescribed by a doctor; the dose and duration may vary depending on the child’s weight and the severity of the infection. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects/interaction

Uses of Biophenicol Succinate Injection 1gm

Bacterial infections.

Directions for Use

Biophenicol Succinate Injection 1gm will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Biophenicol Succinate Injection 1gm belongs to the group of antibiotic medicines used to treat severe bacterial infections such as meningitis and typhoid. It should only be used when other antibiotics are not suitable. Biophenicol Succinate Injection 1gm contains ‘Chloramphenicol’ that works by preventing the synthesis of essential proteins which are necessary for vital bacterial functions. Thus, it kills the bacteria and helps in treating infection. Biophenicol Succinate Injection 1gm is a broad-spectrum antibiotic which is active against both gram-positive and gram-negative bacteria.

Storage

keep Biophenicol Succinate Injection 1gm out of sight and reach of children.

Side effects of Biophenicol Succinate Injection 1gm

Bone Marrow Suppression

Aim for at least five servings of a well-balanced diet per day that is full of vibrant fruits and vegetables.
Eat more whole foods, lean meats, and plant-based foods, and eat healthy fruits like bananas, oranges, and berries.
Limit alcohol intake and abstain from smoking to promote general wellbeing.

Aplastic Anemia

Treatments include blood transfusions, immunosuppressive therapy and bone marrow transplants.
Get adequate sleep and rest.
Avoid high-contact sports and activities.

Anemia Due To Damage To Stem Cells

If you experience significant anemia symptoms like weakness, fatigue (overtiredness), or shortness of breath, consult your doctor to determine the medication causing it. Your doctor may advise you to discontinue that medicine immediately and recommend supportive care.
In certain cases, blood transfusions, immunosuppressive therapy or bone marrow transplants may be required to stabilize the patient based on the severity and underlying cause of anemia.
Take iron supplements if advised by your doctor.
Include foods rich in iron like dark leafy greens, legumes, red meat, fish, poultry and fortified cereals in your diet.
In some cases, vitamin B 12 supplements may be advised if vitamin B12 deficiency is a contributing factor.

Low Platelet Count

Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
If you experience severe bleeding or bruising, seek emergency medical attention immediately.

Low Level Of Granulocytes (A Type Of White Blood Cells)

Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
Get sufficient sleep and manage stress which helps in improving white blood cell count.
Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.

Vomiting

To prevent, manage, and treat Constipation caused by medication usage, follow these steps:

Preventing Vomiting (Before it Happens)
Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
Having a small meal before taking your medication can help reduce nausea and vomiting.
Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
Managing Vomiting (If it Happens)
Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
What to Do if Vomiting Persists
Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Loose And Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Drug Warnings

Do not take Biophenicol Succinate Injection 1gm if you are allergic to any of its components; or if you are pregnant or breastfeeding. Inform your doctor if you are taking any medicines which may cause bone marrow depression if you have a cold, throat infection, viral influenza, kidney or liver problems, or if you are about to be or have recently been vaccinated. Let your doctor know if you are taking any prescription/non-prescription medicines or herbal/vitamin supplements.

Drug-Drug Interactions

ChloramphenicolFlibanserin

Critical

ChloramphenicolTriazolam

Critical

Drug-Drug Interactions

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ChloramphenicolFlibanserin

Critical

How does the drug interact with Biophenicol Succinate Injection 1gm:
Taking Flibanserin with Biophenicol Succinate Injection 1gm may significantly increases the blood levels of flibanserin

How to manage the interaction:
Taking Biophenicol Succinate Injection 1gm with Flibanserin is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, lightheadedness, and fainting. Do not discontinue any medication without consulting a doctor.

ChloramphenicolTriazolam

Critical

How does the drug interact with Biophenicol Succinate Injection 1gm:
Taking Biophenicol Succinate Injection 1gm with triazolam can increased the effects of Biophenicol Succinate Injection 1gm.

How to manage the interaction:
Taking Triazolam with Biophenicol Succinate Injection 1gm is not recommended, but can be taken together if prescribed by a doctor. In case you experience any unusual symptoms, consult a doctor. However, if you experience any unusual symptoms contact your doctor. Do not discontinue any medications without consulting a doctor.

ChloramphenicolLomitapide

Critical

How does the drug interact with Biophenicol Succinate Injection 1gm:
Taking lomitapide with Biophenicol Succinate Injection 1gm can significantly increase the blood levels of lomitapide.

How to manage the interaction:
Taking Biophenicol Succinate Injection 1gm with Lomitapide is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, dark colored urine, light colored stools, and yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.

ChloramphenicolPimozide

Severe

How does the drug interact with Biophenicol Succinate Injection 1gm:
When Pimozide is taken with Biophenicol Succinate Injection 1gm, the amount of Pimozide in the blood increases which increase the risk of an irregular heart rhythm and other side effects.

How to manage the interaction:
Although taking Biophenicol Succinate Injection 1gm and Pimozide together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience dizziness, lightheadedness, fainting, shortness of breath contact your doctor right away. Do not stop using any medications without first talking to your doctor.

ChloramphenicolVoclosporin

Severe

How does the drug interact with Biophenicol Succinate Injection 1gm:
Taking Biophenicol Succinate Injection 1gm with Voclosporin can increase the blood levels of voclosporin which increases risk of serious side effects.

How to manage the interaction:
Although taking Biophenicol Succinate Injection 1gm and Voclosporin together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you have any unusual symptoms, it's important to contact a doctor. Do not stop using any medications without talking to a doctor.

ChloramphenicolButorphanol

Severe

How does the drug interact with Biophenicol Succinate Injection 1gm:
Taking Biophenicol Succinate Injection 1gm and Butorphanol can significantly increase the blood levels of Butorphanol that may increase the risk of side effects.

How to manage the interaction:
Although taking Biophenicol Succinate Injection 1gm with Butorphanol can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience dizziness, lightheadedness, headache, flushing, fainting, and heart palpitations feeling tired, having trouble moving, difficulty swallowing or having seizures contact your doctor know. Do not stop using any medications without a doctor's advice.

ChloramphenicolNaloxegol

Severe

How does the drug interact with Biophenicol Succinate Injection 1gm:
Taking Naloxegol and Biophenicol Succinate Injection 1gm can significantly increase the blood levels of naloxegol that may increase the risk of side effects.

How to manage the interaction:
Although taking Biophenicol Succinate Injection 1gm and Naloxegol together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience sweating, runny nose, or abdominal pain contact your doctor know right away. Do not stop using any medications without a doctor's advice.

ChloramphenicolBCG vaccine

Severe

How does the drug interact with Biophenicol Succinate Injection 1gm:
When BCG vaccine is used with Biophenicol Succinate Injection 1gm, its effectiveness of BCG vaccine may be reduced.

How to manage the interaction:
Although there is a possible interaction between Biophenicol Succinate Injection 1gm and BCG vaccine, you can take these medicines together if prescribed by your doctor. However, consult your doctor if you experience any unusual symptoms. Do not discontinue any medications without first consulting your doctor.

ChloramphenicolCladribine

Severe

How does the drug interact with Biophenicol Succinate Injection 1gm:
Taking cladribine together with Biophenicol Succinate Injection 1gm may increase the risk of infections.

How to manage the interaction:
There may be a possibility of interaction between Cladribine and Biophenicol Succinate Injection 1gm, but it can be taken if prescribed by a doctor. If you have any of these symptoms - fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination, make sure to contact your doctor right away. Do not discontinue any medications without consulting a doctor.

ChloramphenicolIvacaftor

Severe

How does the drug interact with Biophenicol Succinate Injection 1gm:
Taking Biophenicol Succinate Injection 1gm and Ivacaftor may increase the blood levels of ivacaftor that increases risk of side effects.

How to manage the interaction:
Although taking Biophenicol Succinate Injection 1gm and Ivacaftor together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes contact a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Antibiotics can alter the useful bacteria in the stomach, which help in digestion. Therefore, you are advised to take foods rich in probiotics, such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.
Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.
Avoid consumption of alcohol and usage of tobacco.

Side Effects of Biophenicol Succinate Injection 1gm

Nausea
Vomiting
Diarrhoea
Headache
Dry mouth

Habit Forming

No

Therapeutic Class

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Author Details

Written By

Santoshini Reddy G

M Pharmacy

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:47 AM IST

We provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Biophenicol Succinate Injection 1gm work?

Biophenicol Succinate Injection 1gm works by preventing the synthesis of essential proteins which are necessary for vital bacterial functions. Thus, it kills bacteria and helps treat infections.

Does Biophenicol Succinate Injection 1gm cause diarrhoea?

Diarrhoea might be a side-effect of Biophenicol Succinate Injection 1gm. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in your stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Does Biophenicol Succinate Injection 1gm cause blood problems?

Biophenicol Succinate Injection 1gm is associated with various forms of anaemia (decreased white, red blood cells and platelets). This may lead to loss of immunity and the development of leukaemia in a few people. Consult a doctor if you have any concerns.

Does Biophenicol Succinate Injection 1gm cause grey syndrome?

Biophenicol Succinate Injection 1gm should be used with great care in newborn babies to avoid grey syndrome, a condition occurring due to excessive toxic chloramphenicol metabolites. Treatment should be stopped immediately if the symptoms are identified.

Does Biophenicol Succinate Injection 1gm cause headache?

Headache could be a side effect of Biophenicol Succinate Injection 1gm. It is not necessary for everyone to experience this side effect. However, if the condition persists or worsens, consult a doctor.

Drug-Drug Interactions Checker List

TOLBUTAMIDE
PHENOBARBITAL
PHENYTOIN
RIFAMPICIN

Disease/Condition Glossary

Bacterial infection: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect the body. It can target any body part and multiply very quickly. Generalized symptoms of bacterial infections are fever, chills, and fatigue. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. Anyone can become infected with a bacterial infection. But, people with a weak immune system or taking immunosuppressive medicines are more prone to bacterial infection.