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Whats That
About Bosutris 400mg Tablet
Bosutris 400mg Tablet is an anti-cancer medicine used in the treatment of Leukemia. Leukemia, also known as blood cancer, is a cancer of blood cells or blood-forming tissues. It causes excessive production of immature white blood cells by the bone marrow and reduces the body’s ability to fight infections. Bosutris 400mg Tablet is used in the treatment of chronic myelogenous leukemia (CML). This medicine is used in patients with chronic, accelerated, or blast phase Ph+ (Philadelphia chromosome-positive) chronic myelogenous leukemia who are resistant or intolerant to prior therapy.
Bosutris 400mg Tablet contains Bosutinib, which belongs to the class of kinase inhibitors. It works by inhibiting the action of abnormal proteins that cause the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce the further spread to other parts of the body.
Bosutris 400mg Tablet may cause certain side effects, such as rash, fatigue, headache, back pain, decreased platelet count, back pain, nausea, vomiting, diarrhea, abdominal pain, loss of appetite, and dizziness. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Bosutris 400mg Tablet should be taken as advised by your doctor. Do not take more than the recommended dose of medicine. Your doctor will decide the dose of Bosutris 400mg Tablet based on the severity of your condition.
Bosutris 400mg Tablet should be avoided if you are allergic to it or any other components present in it. Let your doctor know about your complete medical history, including current medication, to rule out any side effects/interactions. Before taking this medicine, inform your doctor if you have liver/kidney disease, gastrointestinal toxicity, myelosuppression, fluid retention, and hepatic toxicity, as may cause serious side effects or worsen such conditions. This medicine is known to cause embryo-fetal toxicity. Hence, inform your doctor if you are pregnant or are planning to become pregnant before starting the treatment with Bosutris 400mg Tablet . Breastfeeding should be discontinued in nursing mothers during the treatment. Bosutris 400mg Tablet is not recommended for use in children below 18 years of age as the safety and efficacy are not established.
Uses of Bosutris 400mg Tablet
Directions for Use
Key Benefits
Bosutris 400mg Tablet contains Bosutinib, which belongs to the class of kinase inhibitors. It works by inhibiting the action of abnormal proteins that cause the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce the further spread to other parts of the body.
Storage
Drug Warnings
Bosutris 400mg Tablet should be avoided if you are allergic to it or any other components present in it. Let your doctor know about your complete medical history, including current medication, to rule out any side effects/interactions. Before taking, inform your doctor if you have liver/kidney disease, diabetes, cardiac problems, increased blood pressure, gastrointestinal toxicity, myelosuppression, fluid retention, and hepatic toxicity, as the use of Bosutris 400mg Tablet in these patients may cause serious side effects. This medicine is known to cause embryo-fetal toxicity. Hence, inform your doctor if you are pregnant or are planning to become pregnant before starting the treatment. Breastfeeding should be discontinued in nursing mothers during the treatment. Bosutris 400mg Tablet is not recommended for use in children below 18 years of age as the safety and efficacy are not established. Avoid alcohol consumption and smoking, as it can lead to serious adverse effects.
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Side Effects of Bosutris 400mg Tablet
Habit Forming
Therapeutic Class
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Disease/Condition Glossary
Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia: Leukemia, also known as blood cancer, is a cancer of blood cells or blood-forming tissues. It causes excessive production of immature white blood cells by the bone marrow and reduces the body’s ability to fight infections. Chronic Myelogenous Leukemia is a type of blood cancer that originates in the myeloid cells or stem cells in your bone marrow. Ph+ chronic myeloid leukemia is a common form of CML that occurs when specific chromosomes swap position. This causes a chromosome abnormality, creating the Philadelphia chromosome. The abnormal chromosomes produce an abnormal protein called Bcr-Abl tyrosine kinase, which then triggers a signal to produce abnormal white blood cells in the bone marrow. Symptoms may include fatigue, fever, weight loss, and loss of appetite.

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Alcohol
Safe if prescribed
Avoid alcohol consumption while on treatment with Bosutris 400mg Tablet to prevent serious adverse effects.
Pregnancy
Consult your doctor
Bosutris 400mg Tablet is not recommended for use in pregnancy as it may harm your fetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before taking Bosutris 400mg Tablet . Your doctor may prescribe this medicine if the benefits outweigh the risks.
Breast Feeding
Consult your doctor
Limited data is available on the effect of Bosutris 400mg Tablet on breastfeeding. Bosutris 400mg Tablet should be avoided during breastfeeding. Hence, inform your doctor if you are breastfeeding. Your doctor may prescribe an alternative based on the symptoms and health condition.
Driving
Safe if prescribed
Bosutris 400mg Tablet may cause dizziness and may make you feel drowsy. Hence, avoid driving or operating machines after taking Bosutris 400mg Tablet or until you become alert.
Liver
Consult your doctor
Bosutris 400mg Tablet is known to cause hepatotoxicity. Hence, inform your doctor if you have a pre-existing or a history of liver disease. A dose adjustment may be needed based on your condition.
Kidney
Consult your doctor
If you have a pre-existing or a history of kidney disease, inform your doctor before taking Bosutris 400mg Tablet . Your doctor may reduce the dose of this medicine or prescribe a suitable alternative based on your condition.
Children
Safe if prescribed
Bosutris 400mg Tablet is not recommended for use in children below 18 years of age as the safety and efficacy are not established.
Heart
Inform your doctor if you have heart disease before using Bosutris 400mg Tablet . Your doctor will prescribe only if the benefits outweigh the risks.
Geriatrics
Consult your doctor
Bosutris 400mg Tablet may require dose adjustment in elderly patients based on their condition and medical requirements.