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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Composition :

OLAPARIB-100MG

Manufacturer/Marketer :

Natco Pharma Ltd

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

About Bracanat 100 Tablet

Bracanat 100 Tablet belongs to a group of medicines known as 'anti-cancer' drugs used to treat various cancers, including Ovarian, breast, pancreatic, and prostate. Cancer is a condition where cells in a specific body part grow and reproduce uncontrollably. The cancerous cells can attack and destroy surrounding healthy tissue, including organs.

Bracanat 100 Tablet contains Olaparib, a targeted drug called a PARP inhibitor. PARP (polyadenosine 5’-diphosphoribose polymerase) is a protein that helps damaged cells repair themselves. Olaparib stops PARP working. Some cancer cells rely on PARP to keep their DNA healthy. So, the cancer cells die when Olaparib stops PARP from repairing DNA damage.

Use this medicine as directed by your doctor. You may sometimes experience shortness of breath (dyspnoea), feeling very tired, pale skin or fast heartbeat, anaemia, feeling sick (nausea), being sick (vomiting), indigestion or heartburn (dyspepsia), loss of appetite, headache, changes in taste of foods (dysgeusia), feeling dizzy, cough and diarrhoea. Most of these side effects may gradually resolve over time. However, if the side effects persist or worsen, consult your doctor.

To treat your condition effectually, continue taking Bracanat 100 Tablet for as long as your doctor has prescribed. Do not stop using the Bracanat 100 Tablet midway. Talk to your doctor before taking Bracanat 100 Tablet if you have severe allergic reactions to Bracanat 100 Tablet or other medicines or suffer from severe infections, renal dysfunction, hepatic disorders and blood cell counts are too low. Avoid taking Bracanat 100 Tablet if you are pregnant or breastfeeding because this Bracanat 100 Tablet can cause harmful effects on the unborn baby. Both women and men using this Bracanat 100 Tablet should use birth control to avoid pregnancy. While on Bracanat 100 Tablet treatment, you should avoid eating grapefruit, Seville oranges or consuming grapefruit juice since it can affect how the medicine works.

Uses of Bracanat 100 Tablet

Cancer (Ovarian cancer, breast cancer, pancreatic cancer, and prostate cancer)

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Directions for Use

Swallow it as a whole with water; do not crush or chew it.

Key Benefits

Bracanat 100 Tablet contains Olaparib, a targeted drug called a PARP inhibitor. PARP is a protein that helps damaged cells to repair themselves. Olaparib stops PARP working. Some cancer cells rely on PARP to keep their DNA healthy. So, the cancer cells die when Olaparib stops PARP from repairing DNA damage. Thus, it treats various cancers, including Ovarian, breast, pancreatic, and prostate. It can be used alone or with other chemotherapy drugs, depending on your type of cancer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Always take this medicine exactly as your doctor or healthcare professional has told you. To treat your condition effectually, continue taking Bracanat 100 Tablet for as long as your doctor has prescribed. Do not stop Bracanat 100 Tablet midway. Talk to your doctor before taking Bracanat 100 Tablet if you have severe allergic reactions to Bracanat 100 Tablet or other medicines or suffer from any medical illness. Avoid taking Bracanat 100 Tablet if you are pregnant or breastfeeding because this Bracanat 100 Tablet can cause harmful effects on the unborn baby. Both women and men using this Bracanat 100 Tablet should use birth control to avoid pregnancy. Do not start Bracanat 100 Tablet unless patients have recovered from haematological damage induced by previous chemotherapy (Grade 1). Check full blood count for cytopenia at baseline and monthly afterwards for clinically significant changes during treatment. For persistent haematological toxicity, discontinue Bracanat 100 Tablet and monitor blood count weekly until recovery. Do not receive any immunization or vaccination without your doctor's approval while taking the Bracanat 100 Tablet .

Diet & Lifestyle Advise

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast, fried, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

[ANTINEOPLASTIC]

All Substitutes & Brand Comparisons

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Alcohol

Safe if prescribed

Avoid alcohol consumption while on treatment with Bracanat 100 Tablet .

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Pregnancy

Consult your doctor

Bracanat 100 Tablet should not be used during pregnancy because it can harm your fetus (newborn baby). Both women of childbearing potential and men must use an effective contraception method while taking Bracanat 100 Tablet and at least for six months later treatment. Your doctor will weigh the benefits and risks before prescribing this medicine.

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Breast Feeding

Consult your doctor

Do not breastfeed during this treatment because the medicine may pass into your milk. Doctors normally advise against breastfeeding throughout this treatment and for one month after the final medication is taken.

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Driving

Safe if prescribed

Bracanat 100 Tablet may affect your reactions and your ability to drive. Do not drive and/or operate machines that require your alertness.

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Liver

Consult your doctor

In patients with mild or moderate liver impairment, there is no need to alter the initial dose. There is no information available on patients with severe liver impairment.

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Kidney

Consult your doctor

In patients with mild or moderate kidney impairment, there is no need to alter the initial dose. There is no information available on patients with severe kidney impairment.

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Children

Safe if prescribed

The safety and effectiveness of Bracanat 100 Tablet in pediatric patients have not been established.

FAQs

Bracanat 100 Tablet contains Olaparib, a targeted drug called a PARP inhibitor. PARP is a protein that helps damaged cells to repair themselves. Olaparib stops PARP working. Some cancer cells rely on PARP to keep their DNA healthy. So, the cancer cells die when Olaparib stops PARP from repairing DNA damage.

If you are allergic to Olaparib or any other ingredients in this medication, are breastfeeding, or have too low blood cell counts, you should not use Bracanat 100 Tablet .

Yes, Bracanat 100 Tablet can cause low neutrophils levels, a type of white blood cells that help fight infections. If your white blood cells become low, you can be at higher risk for infections. Tell your doctor if you develop a fever or have an infection.

Do not have immunizations/vaccinations without talking to your doctor first. Also, avoid contact with people who recently had immunizations /vaccinations.

Yes, Olaparib was generally a well-tolerated medication. Take Bracanat 100 Tablet pills exactly as directed by your healthcare provider. Do not change your dose or stop taking Bracanat 100 Tablet unless your healthcare physician instructs you. If you encounter side symptoms, your healthcare provider may temporarily discontinue your Bracanat 100 Tablet therapy or adjust your Bracanat 100 Tablet dose.

Country of origin

India

Manufacturer/Marketer address

Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India
Other Info - BRA0270

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