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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Whats That

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Composition :

OLAPARIB-100MG

Manufacturer/Marketer :

Adley Formulations

Consume Type :

ORAL

Return Policy :

Not Returnable

About Canrib Tablet 60's

Canrib Tablet 60's belongs to a group of medicines known as 'anti-cancer' drugs used to treat various cancers, including Ovarian, breast, pancreatic, and prostate. Cancer is a condition where cells in a specific body part grow and reproduce uncontrollably. The cancerous cells can attack and destroy surrounding healthy tissue, including organs.

Canrib Tablet 60's contains Olaparib, a targeted drug called a PARP inhibitor. PARP (polyadenosine 5’-diphosphoribose polymerase) is a protein that helps damaged cells repair themselves. Olaparib stops PARP working. Some cancer cells rely on PARP to keep their DNA healthy. So, the cancer cells die when Olaparib stops PARP from repairing DNA damage.

Use this medicine as directed by your doctor. You may sometimes experience shortness of breath (dyspnoea), feeling very tired, pale skin or fast heartbeat, anaemia, feeling sick (nausea), being sick (vomiting), indigestion or heartburn (dyspepsia), loss of appetite, headache, changes in taste of foods (dysgeusia), feeling dizzy, cough and diarrhoea. Most of these side effects may gradually resolve over time. However, if the side effects persist or worsen, consult your doctor.

To treat your condition effectually, continue taking Canrib Tablet 60's for as long as your doctor has prescribed. Do not stop using the Canrib Tablet 60's midway. Talk to your doctor before taking Canrib Tablet 60's if you have severe allergic reactions to Canrib Tablet 60's or other medicines or suffer from severe infections, renal dysfunction, hepatic disorders and blood cell counts are too low. Avoid taking Canrib Tablet 60's if you are pregnant or breastfeeding because this Canrib Tablet 60's can cause harmful effects on the unborn baby. Both women and men using this Canrib Tablet 60's should use birth control to avoid pregnancy. While on Canrib Tablet 60's treatment, you should avoid eating grapefruit, Seville oranges or consuming grapefruit juice since it can affect how the medicine works.

Uses of Canrib Tablet 60's

Cancer (Ovarian cancer, breast cancer, pancreatic cancer, and prostate cancer)

Directions for Use

Swallow it as a whole with water; do not crush or chew it.

Medicinal Benefits

Canrib Tablet 60's contains Olaparib, a targeted drug called a PARP inhibitor. PARP is a protein that helps damaged cells to repair themselves. Olaparib stops PARP working. Some cancer cells rely on PARP to keep their DNA healthy. So, the cancer cells die when Olaparib stops PARP from repairing DNA damage. Thus, it treats various cancers, including Ovarian, breast, pancreatic, and prostate. It can be used alone or with other chemotherapy drugs, depending on your type of cancer.

Storage

Keep Canrib Tablet 60's out of reach and sight of children.

Drug Warnings

Always take this medicine exactly as your doctor or healthcare professional has told you. To treat your condition effectually, continue taking Canrib Tablet 60's for as long as your doctor has prescribed. Do not stop Canrib Tablet 60's midway. Talk to your doctor before taking Canrib Tablet 60's if you have severe allergic reactions to Canrib Tablet 60's or other medicines or suffer from any medical illness. Avoid taking Canrib Tablet 60's if you are pregnant or breastfeeding because this Canrib Tablet 60's can cause harmful effects on the unborn baby. Both women and men using this Canrib Tablet 60's should use birth control to avoid pregnancy. Do not start Canrib Tablet 60's unless patients have recovered from haematological damage induced by previous chemotherapy (Grade 1). Check full blood count for cytopenia at baseline and monthly afterwards for clinically significant changes during treatment. For persistent haematological toxicity, discontinue Canrib Tablet 60's and monitor blood count weekly until recovery. Do not receive any immunization or vaccination without your doctor's approval while taking the Canrib Tablet 60's.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Canrib Tablet:
Using Ceritinib and Canrib Tablet can increase the blood levels of Canrib Tablet.

How to manage the interaction:
Although there is a interaction between ceritinib and Canrib Tablet, it can be taken if advised by your doctor. However, if you experience any symptoms like paleness, weakness, dizziness, fainting, unusual bruising or bleeding, fever, chills, loose stools, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Canrib Tablet:
Co-administration of Dexamethasone together with Canrib Tablet can reduce the blood levels of Canrib Tablet.

How to manage the interaction:
Although taking Canrib Tablet and Dexamethasone together can evidently cause an interaction, it can be taken if a doctor has suggested it. Your doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without talking to a doctor.
How does the drug interact with Canrib Tablet:
Taking Canrib Tablet with rifampicin can decrease the blood levels of Canrib Tablet, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Canrib Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Canrib Tablet:
When Canrib Tablet is taken with Infliximab, it can cause Canrib Tablet to be broken down faster in the body. This can increase the risk or severity of developing serious infections.

How to manage the interaction:
Co-administration of Canrib Tablet with Infliximab can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle aches, trouble breathing, losing weight, or pain or burning when you pee, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Canrib Tablet:
Using Atazanavir and Canrib Tablet can increase the blood levels of Canrib Tablet. This can increase the risk and/or severity of side effects Canrib Tablet.

How to manage the interaction:
Combining Atazanavir and Canrib Tablet can lead to an interaction, but it can be taken if your doctor advises. However, if you experience paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhoea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Canrib Tablet:
Coadministration of Phenytoin and Canrib Tablet may decrease the blood levels of Canrib Tablet, which may make Canrib Tablet less effective.

How to manage the interaction:
Although taking Phenytoin and Canrib Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Without consulting a doctor, never stop taking any drugs.
OlaparibDelavirdine
Severe
How does the drug interact with Canrib Tablet:
Using Delavirdine and Canrib Tablet can increase the blood levels of Canrib Tablet. This can increase the risk and/or severity of side effects such as nausea, vomiting, diarrhea, indigestion, loss of appetite, abdominal pain or discomfort, lung problems, and impaired bone marrow function resulting in low numbers of different types of blood cells.

How to manage the interaction:
Combining Delavirdine and Canrib Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Canrib Tablet:
Using Ribociclib and Canrib Tablet can increase the blood levels of Canrib Tablet. This can increase the risk and/or severity of side effects such as nausea, vomiting, diarrhea, indigestion, loss of appetite, abdominal pain or discomfort, lung problems, and impaired bone marrow function resulting in low numbers of different types of blood cells.

How to manage the interaction:
Combining Ribociclib and Canrib Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Canrib Tablet:
Combining Deferiprone and Canrib Tablet can increase the risk of lowering white blood cell count and affect white blood cells or bone marrow function.

How to manage the interaction:
Combining Deferiprone and Canrib Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without first consulting your doctor.
OlaparibFosamprenavir
Severe
How does the drug interact with Canrib Tablet:
Using Fosamprenavir and Canrib Tablet can increase the blood levels of Canrib Tablet. This can increase the risk and/or severity of side effects such as nausea, vomiting, diarrhea, indigestion, loss of appetite, abdominal pain or discomfort, lung problems, and impaired bone marrow function resulting in low numbers of different types of blood cells.

How to manage the interaction:
Combining Fosamprenavir and Canrib Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast, fried, processed meats, refined carbs and added sugars.

Side Effects of Canrib Tablet 60's

  • Feeling sick (nausea)
  • Being sick (vomiting)
  • Feeling tired or weak (fatigue)
  • Feeling very tired
  • Indigestion or heartburn (dyspepsia)
  • Loss of appetite
  • Headache
  • Changes in the taste of foods (dysgeusia)
  • Feeling dizzy
  • Cough
  • Shortness of breath (dyspnoea)
  • Diarrhoea
  • Low white blood cell count (leukopenia or neutropenia)
  • Rash
  • Sore mouth (stomatitis)
  • Upper abdominal pain (pain in the stomach area under the ribs)
  • Blood clot in a deep vein, usually in the leg (venous thrombosis)

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Canrib Tablet 60's contains Olaparib, a targeted drug called a PARP inhibitor. PARP is a protein that helps damaged cells to repair themselves. Olaparib stops PARP working. Some cancer cells rely on PARP to keep their DNA healthy. So, the cancer cells die when Olaparib stops PARP from repairing DNA damage.

If you are allergic to Olaparib or any other ingredients in this medication, are breastfeeding, or have too low blood cell counts, you should not use Canrib Tablet 60's.

Yes, Canrib Tablet 60's can cause low neutrophils levels, a type of white blood cells that help fight infections. If your white blood cells become low, you can be at higher risk for infections. Tell your doctor if you develop a fever or have an infection.

Do not have immunizations/vaccinations without talking to your doctor first. Also, avoid contact with people who recently had immunizations /vaccinations.

Yes, Olaparib was generally a well-tolerated medication. Take Canrib Tablet 60's pills exactly as directed by your healthcare provider. Do not change your dose or stop taking Canrib Tablet 60's unless your healthcare physician instructs you. If you encounter side symptoms, your healthcare provider may temporarily discontinue your Canrib Tablet 60's therapy or adjust your Canrib Tablet 60's dose.

Drug-Drug Interactions Checker List

  • AMPRENAVIR
  • DARUNAVIR
  • APREPITANT
  • BCG VACCINE
  • DENGUE VACCINE
  • MUMPS (LIVE ATTENUATED)
  • CIPROFLOXACIN
  • FLUCONAZOLE
  • ITRACONAZOLE

Special Advise

  • Pregnancy testing is recommended for females of reproductive potential prior to initiating treatment with Canrib Tablet 60's.
  • Canrib Tablet 60's should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Canrib Tablet 60's.
  • Monitor complete blood count for cytopenia at baseline and monthly for clinically significant changes during treatment.
  • Your doctor may get routine blood tests done to monitor your liver function, electrolyte levels, and blood cell count in your blood.
  • Peripheral blood counts should be frequently monitored during Canrib Tablet 60's treatment and, when appropriate, until recovery is achieved.
  • Do not donate sperm during treatment with Canrib Tablet 60's for three months after your last dose.

Disease/Condition Glossary

Cancer: Cancer is a condition where cells in a specific body part grow and reproduce uncontrollably. The cancerous cells can invade and destroy surrounding healthy tissue, including organs. Cancer sometimes begins in one body part before spreading to other areas.

Ovarian cancer: Ovarian cancer begins in the ovaries (one of a pair of female reproductive glands in which the ova, or eggs, are formed).

Breast cancer: Breast cancer is a type of cancer that develops in breast cells stimulated by a female sex hormone called estrogen. Breast cancer may form in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), and the fatty tissue or the fibrous connective tissue within the breast. The tumour cells invade other healthy breast cells and travel to lymph nodes, a primary pathway for the cancer cells to move to other body parts. Symptoms of breast cancer include a lump in the breast or tissue thickening, which feels different than the normal surrounding tissues, breast pain, redness, swelling, and nipple discharge other than breast milk.

Prostate cancer: Prostate cancer is a type of cancer that only occurs in men and affects the prostate gland, a tiny gland under the bladder that produces semen. Inability to urinate easily, pain, numbness, or sexual issues are among the symptoms. For men, it is the most typical type of cancer. Although the exact cause of prostate cancer is unknown, it may be brought on by family history, chemical exposure, or both. Prostate cancer risk factors include a family history of the disease, advanced age, obesity, and genetic changes.

Have a query?

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Alcohol

Caution

Avoid alcohol consumption while on treatment with Canrib Tablet 60's.

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Pregnancy

Unsafe

Canrib Tablet 60's should not be used during pregnancy because it can harm your fetus (newborn baby). Both women of childbearing potential and men must use an effective contraception method while taking Canrib Tablet 60's and at least for six months later treatment. Your doctor will weigh the benefits and risks before prescribing this medicine.

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Breast Feeding

Unsafe

Do not breastfeed during this treatment because the medicine may pass into your milk. Doctors normally advise against breastfeeding throughout this treatment and for one month after the final medication is taken.

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Driving

Caution

Canrib Tablet 60's may affect your reactions and your ability to drive. Do not drive and/or operate machines that require your alertness.

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Liver

Caution

In patients with mild or moderate liver impairment, there is no need to alter the initial dose. There is no information available on patients with severe liver impairment.

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Kidney

Caution

In patients with mild or moderate kidney impairment, there is no need to alter the initial dose. There is no information available on patients with severe kidney impairment.

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Children

Caution

The safety and effectiveness of Canrib Tablet 60's in pediatric patients have not been established.

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