Bracanat 150 Tablet 30's
MRP ₹7453
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About Bracanat 150 Tablet
Bracanat 150 Tablet belongs to a group of medicines known as 'anti-cancer' drugs used to treat various cancers, including Ovarian, breast, pancreatic, and prostate. Cancer is a condition where cells in a specific body part grow and reproduce uncontrollably. The cancerous cells can attack and destroy surrounding healthy tissue, including organs.
Bracanat 150 Tablet contains Olaparib, a targeted drug called a
Use this medicine as directed by your doctor. You may sometimes experience shortness of breath (dyspnoea), feeling very tired, pale skin or fast heartbeat, anaemia, feeling sick (nausea), being sick (vomiting), indigestion or heartburn (dyspepsia), loss of appetite, headache, changes in taste of foods (dysgeusia), feeling dizzy, cough and diarrhoea. Most of these side effects may gradually resolve over time. However, if the side effects persist or worsen, consult your doctor.
To treat your condition effectually, continue taking Bracanat 150 Tablet for as long as your doctor has prescribed. Do not stop using the Bracanat 150 Tablet midway. Talk to your doctor before taking Bracanat 150 Tablet if you have severe allergic reactions to Bracanat 150 Tablet or other medicines or suffer from severe infections, renal dysfunction, hepatic disorders and blood cell counts are too low. Avoid taking Bracanat 150 Tablet if you are pregnant or breastfeeding because this Bracanat 150 Tablet can cause harmful effects on the unborn baby. Both women and men using this Bracanat 150 Tablet should use birth control to avoid pregnancy. While on Bracanat 150 Tablet treatment, you should avoid eating grapefruit, Seville oranges or consuming grapefruit juice since it can affect how the medicine works.
Uses of Bracanat 150 Tablet
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Directions for Use
Key Benefits
Bracanat 150 Tablet contains Olaparib, a targeted drug called a
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- Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
- Divide your daily food intake into smaller, more frequent meals to reduce nausea.
- Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
- Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
- Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
- Use ginger (tea, ale, or candies) to help relieve nausea.
- Get adequate rest and also avoid strenuous activities that can worsen nausea.
- Talk to your doctor about taking anti-nausea medication if your nausea is severe.
- Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
- Rest well; get enough sleep.
- Eat a balanced diet and drink enough water.
- Manage stress with yoga and meditation.
- Limit alcohol and caffeine.
- Physical activities like walking or jogging might help boost energy and make you feel less tired.
- Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
- Consume vitamin C-rich foods as they aid iron absorption.
- Limit tea, cocoa, and coffee as these can slow iron absorption.
- Exercise regularly; however, do not overdo it.
- Preventing Vomiting (Before it Happens)
- Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
- Having a small meal before taking your medication can help reduce nausea and vomiting.
- Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
- Managing Vomiting (If it Happens)
- Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
- What to Do if Vomiting Persists
- Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
- Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
- Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
- Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
- Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
- Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
- Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
- Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
- Hydrate your body: Drink enough water to prevent dehydration and headaches.
- Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
- Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
- Take rest: lie down in a quiet, dark environment.
- Cold or warm compresses can help reduce tension.
- Stay Upright: Maintain good posture to keep symptoms from getting worse.
- To treat headaches naturally, try acupuncture or massage therapy.
- Over-the-counter pain relievers include acetaminophen and ibuprofen.
- Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
- Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
- Frequent Headaches: If you get reoccurring headaches, consult your doctor.
- Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
- Regularly brush and floss your teeth.
- Rinse your mouth with water and baking soda a solution to neutralize acid in the mouth. This makes your food taste as it should.
- Drink plenty of water or non-caffeinated drinks to prevent dry mouth which may lead to altered taste.
- Try ginger, peppermint, fruit or green teas, lemonade, ginger ale or fruit juice to help mask unpleasant tastes.
- Try sucking on sugar-free ice pops or ice cubes to prevent dry mouth.
Drug Warnings
Always take this medicine exactly as your doctor or healthcare professional has told you. To treat your condition effectually, continue taking Bracanat 150 Tablet for as long as your doctor has prescribed. Do not stop Bracanat 150 Tablet midway. Talk to your doctor before taking Bracanat 150 Tablet if you have severe allergic reactions to Bracanat 150 Tablet or other medicines or suffer from any medical illness. Avoid taking Bracanat 150 Tablet if you are pregnant or breastfeeding because this Bracanat 150 Tablet can cause harmful effects on the unborn baby. Both women and men using this Bracanat 150 Tablet should use birth control to avoid pregnancy. Do not start Bracanat 150 Tablet unless patients have recovered from haematological damage induced by previous chemotherapy (Grade 1). Check full blood count for cytopenia at baseline and monthly afterwards for clinically significant changes during treatment. For persistent haematological toxicity, discontinue Bracanat 150 Tablet and monitor blood count weekly until recovery. Do not receive any immunization or vaccination without your doctor's approval while taking the Bracanat 150 Tablet .
Drug-Drug Interactions
Drug-Drug Interactions
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Co-administration of Enzalutamide and Bracanat 150 Tablet may decrease the blood levels of Bracanat 150 Tablet, which may make Bracanat 150 Tablet less effective in treating your condition.
How to manage the interaction:
Although taking Enzalutamide and Bracanat 150 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue any medications without a doctor's advice.
Using adalimumab together with Bracanat 150 Tablet may increase the risk of infections.
How to manage the interaction:
Combining adalimumab and Bracanat 150 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without consulting your doctor.
Using Delavirdine and Bracanat 150 Tablet can increase the blood levels of Bracanat 150 Tablet. This can increase the risk and/or severity of side effects such as nausea, vomiting, diarrhea, indigestion, loss of appetite, abdominal pain or discomfort, lung problems, and impaired bone marrow function resulting in low numbers of different types of blood cells.
How to manage the interaction:
Combining Delavirdine and Bracanat 150 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without first consulting your doctor.
Combining Deferiprone and Bracanat 150 Tablet can increase the risk of lowering white blood cell count and affect white blood cells or bone marrow function.
How to manage the interaction:
Combining Deferiprone and Bracanat 150 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without first consulting your doctor.
Co-administration of Dexamethasone together with Bracanat 150 Tablet can reduce the blood levels of Bracanat 150 Tablet.
How to manage the interaction:
Although taking Bracanat 150 Tablet and Dexamethasone together can evidently cause an interaction, it can be taken if a doctor has suggested it. Your doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without talking to a doctor.
Using Fosamprenavir and Bracanat 150 Tablet can increase the blood levels of Bracanat 150 Tablet. This can increase the risk and/or severity of side effects such as nausea, vomiting, diarrhea, indigestion, loss of appetite, abdominal pain or discomfort, lung problems, and impaired bone marrow function resulting in low numbers of different types of blood cells.
How to manage the interaction:
Combining Fosamprenavir and Bracanat 150 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without first consulting your doctor.
When Bracanat 150 Tablet is taken with Infliximab, it can cause Bracanat 150 Tablet to be broken down faster in the body. This can increase the risk or severity of developing serious infections.
How to manage the interaction:
Co-administration of Bracanat 150 Tablet with Infliximab can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle aches, trouble breathing, losing weight, or pain or burning when you pee, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
Using Certolizumab together with Bracanat 150 Tablet may increase the risk of infections.
How to manage the interaction:
Combining Certolizumab and Bracanat 150 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without first consulting your doctor.
Taking Ritonavir and Bracanat 150 Tablet may significantly increase the blood levels of Bracanat 150 Tablet.
How to manage the interaction:
There may be a possibility of interaction between Bracanat 150 Tablet and Ritonavir, but it can be taken if prescribed by a doctor. However, if you experience tiredness, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination contact a doctor. Do not stop using any medications without talking to a doctor.
Using Indinavir and Bracanat 150 Tablet can increase the blood levels of Bracanat 150 Tablet. This can increase the risk and/or severity of side effects such as nausea, vomiting, diarrhea, indigestion, loss of appetite, abdominal pain or discomfort, lung problems, and impaired bone marrow function resulting in low numbers of different types of blood cells.
How to manage the interaction:
Combining Indinavir and Bracanat 150 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without first consulting your doctor.
Drug-Food Interactions
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Diet & Lifestyle Advise
- De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
- Performing yoga may also help in improving both physical and mental health.
- Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
- Eat a healthy diet and exercise regularly to maintain proper weight.
- Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
- Get optimal sleep; rest well.
- Avoid smoking and alcohol consumption.
- Avoid fast, fried, processed meats, refined carbs and added sugars.
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Alcohol
Safe if prescribed
Avoid alcohol consumption while on treatment with Bracanat 150 Tablet .
Pregnancy
Consult your doctor
Bracanat 150 Tablet should not be used during pregnancy because it can harm your fetus (newborn baby). Both women of childbearing potential and men must use an effective contraception method while taking Bracanat 150 Tablet and at least for six months later treatment. Your doctor will weigh the benefits and risks before prescribing this medicine.
Breast Feeding
Consult your doctor
Do not breastfeed during this treatment because the medicine may pass into your milk. Doctors normally advise against breastfeeding throughout this treatment and for one month after the final medication is taken.
Driving
Safe if prescribed
Bracanat 150 Tablet may affect your reactions and your ability to drive. Do not drive and/or operate machines that require your alertness.
Liver
Consult your doctor
In patients with mild or moderate liver impairment, there is no need to alter the initial dose. There is no information available on patients with severe liver impairment.
Kidney
Consult your doctor
In patients with mild or moderate kidney impairment, there is no need to alter the initial dose. There is no information available on patients with severe kidney impairment.
Children
Safe if prescribed
The safety and effectiveness of Bracanat 150 Tablet in pediatric patients have not been established.
FAQs
Bracanat 150 Tablet contains Olaparib, a targeted drug called a PARP inhibitor. PARP is a protein that helps damaged cells to repair themselves. Olaparib stops PARP working. Some cancer cells rely on PARP to keep their DNA healthy. So, the cancer cells die when Olaparib stops PARP from repairing DNA damage.
If you are allergic to Olaparib or any other ingredients in this medication, are breastfeeding, or have too low blood cell counts, you should not use Bracanat 150 Tablet .
Yes, Bracanat 150 Tablet can cause low neutrophils levels, a type of white blood cells that help fight infections. If your white blood cells become low, you can be at higher risk for infections. Tell your doctor if you develop a fever or have an infection.
Do not have immunizations/vaccinations without talking to your doctor first. Also, avoid contact with people who recently had immunizations /vaccinations.
Yes, Olaparib was generally a well-tolerated medication. Take Bracanat 150 Tablet pills exactly as directed by your healthcare provider. Do not change your dose or stop taking Bracanat 150 Tablet unless your healthcare physician instructs you. If you encounter side symptoms, your healthcare provider may temporarily discontinue your Bracanat 150 Tablet therapy or adjust your Bracanat 150 Tablet dose.
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Reference
- https://www.myeloma.org.uk/wp-content/uploads/2023/04/Myeloma-UK-Panobinostat-Treatment-Guide.pdf
- https://www.lynparza.com/
- https://medlineplus.gov/druginfo/meds/a614060.html#:~:text=Olaparib%20is%20used%20alone%20or,tissue%20that%20lines%20the%20abdomen)
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/208558s001lbl.pdf
- https://www.medicines.org.uk/emc/product/9204/pil#gref
- https://reference.medscape.com/drug/lynparza-olaparib-999934
- https://www.medicines.org.uk/emc/files/pil.9204.pdf
- https://www.lynparzahcp.com/
- https://www.cancerresearchuk.org/about-cancer/treatment/drugs/olaparib-lynparza#:~:text=Olaparib%20stops%20PARP%20working.&text=healthy.,damage%2C%20the%20cancer%20cells%20die.
- https://www.lynparza.com/what-is-lynparza.html
- https://www.drugs.com/drug-interactions/olaparib-index.html?filter=3
