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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Non returnable*
COD available

Online payment accepted

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Whats That

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Composition

PIROXICAM-10MG

Manufacturer/Marketer

Wockhardt Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About BREXIC INJECTION 2ML

BREXIC INJECTION 2ML belongs to the group of medications known as NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) used to relieve symptoms like pain and inflammation associated with rheumatoid arthritis, osteoarthritis, and musculoskeletal disorders. Osteoarthritis is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering (cartilage). Rheumatoid arthritis is an auto-immune disease (the body's immune system attacks its tissue), leading to joint pain and damage.

BREXIC INJECTION 2ML contains 'Piroxicam' that works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins. Prostaglandins are produced at the injury site and cause pain and swelling. By blocking the effect of COX enzymes, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

BREXIC INJECTION 2ML will be administered by a healthcare professional; do not self-administer. In some cases, you may experience certain common side-effects such as injection site reactions, diarrhoea, dizziness, nausea, vomiting, and stomach pain. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to speak to your doctor if you experience these side effects persistently.

BREXIC INJECTION 2ML may increase the risk of heart attack and the chances of stomach ulcers and bleeding. If you have had any recent heart bypass surgery, do not take BREXIC INJECTION 2ML unless prescribed by the doctor. Consult your doctor before taking BREXIC INJECTION 2ML if you are pregnant or breastfeeding. BREXIC INJECTION 2ML may cause dizziness, so drive with caution. BREXIC INJECTION 2ML is not recommended for children as safety and efficacy have not been established. Avoid consuming alcohol along with BREXIC INJECTION 2ML as it could lead to increased drowsiness and dizziness. It could also increase the risk of stomach bleeding.

Uses of BREXIC INJECTION 2ML

Musculoskeletal pain, Osteoarthritis, Rheumatoid arthritis

Directions for Use

BREXIC INJECTION 2ML will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

BREXIC INJECTION 2ML belongs to the group of pain killers known as NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) used to treat musculoskeletal pain. It is also used to relieve symptoms associated with osteoarthritis, and rheumatoid arthritis, such as stiffness, swelling, and joint pain. BREXIC INJECTION 2ML works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins. Prostaglandins are produced at the injury site and cause pain and swelling. By blocking the effect of COX enzymes, fewer prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Storage

Store in a cool and dry place away from sunlight

Side Effects of BREXIC INJECTION 2ML

  • Injection site reactions
  • Diarrhoea
  • Dizziness
  • Nausea
  • Vomiting
  • Stomach pain

Drug Warnings

BREXIC INJECTION 2ML may increase the risk of serious heart-related problems, like heart attack and stroke. So, if you are a heart patient, let your doctor know before taking BREXIC INJECTION 2ML. Besides this, BREXIC INJECTION 2ML may also cause stomach and intestinal bleeding/ulcers, so let your doctor know if you have these problems. Do not take BREXIC INJECTION 2ML if you have had heart bypass surgery or coronary artery bypass graft surgery (CABG) as it can increase the risk of a heart attack. Consult your doctor before taking BREXIC INJECTION 2ML if you are pregnant or breastfeeding. BREXIC INJECTION 2ML may cause dizziness, so drive only if you are alert. BREXIC INJECTION 2ML is not recommended for children as safety has not been established. Avoid consuming alcohol along with BREXIC INJECTION 2ML as it could lead to increased dizziness and may increase the risk of stomach bleeding. Inform your doctor before taking BREXIC INJECTION 2ML if you have asthma, water retention (oedema) or high blood pressure, stuffy/runny nose, nasal polyps, liver or kidney problems.

Drug-Drug Interactions

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PiroxicamCidofovir
Critical
PiroxicamKetorolac tromethamine
Critical

Drug-Drug Interactions

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PiroxicamCidofovir
Critical
How does the drug interact with Brexic Injection 2ml:
Co-administration of Cidofovir with Brexic Injection 2ml can increase the risk of kidney problems.

How to manage the interaction:
Taking Brexic Injection 2ml with Cidofovir is not recommended as it can cause an interaction, it can be taken together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
PiroxicamKetorolac tromethamine
Critical
How does the drug interact with Brexic Injection 2ml:
Using ketorolac tromethamine together with Brexic Injection 2ml may increase the risk of side effects.

How to manage the interaction:
Taking Brexic Injection 2ml with Ketorolac tromethamine is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. Consult a doctor if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop using any medications without talking to a doctor.
PiroxicamDeferasirox
Severe
How does the drug interact with Brexic Injection 2ml:
Using deferasirox together with Brexic Injection 2ml may increase the risk of ulcers.

How to manage the interaction:
Co-administration of Brexic Injection 2ml with Deferasirox can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have symptoms like stomach pain, bloating, dizziness, or black stools, it's important to consult a doctor. Do not stop using any medications without a doctor's advice.
PiroxicamTenofovir disoproxil
Severe
How does the drug interact with Brexic Injection 2ml:
Coadministration of Brexic Injection 2ml and Tenofovir disoproxil can increase the risk of kidney damage.

How to manage the interaction:
Co-administration of Tenofovir disoproxil with Brexic Injection 2ml can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, decreased appetite, increased or decreased urine, weight gain or loss that occurs suddenly, swelling, difficulty breathing, muscle pain, dizziness, and irregular heartbeat, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
PiroxicamMipomersen
Severe
How does the drug interact with Brexic Injection 2ml:
Taking Brexic Injection 2ml and Mipomersen together can increase the risk of liver damage.

How to manage the interaction:
There may be a possibility of interaction between Brexic Injection 2ml and Mipomersen, but it can be taken if prescribed by a doctor. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
PiroxicamMethotrexate
Severe
How does the drug interact with Brexic Injection 2ml:
Coadministration of Methotrexate with Brexic Injection 2ml can increase the levels and side effects.

How to manage the interaction:
Although there is a possible interaction between Brexic Injection 2ml and methotrexate, it can be taken if prescribed by a doctor. However, if you experience any symptoms such as mouth ulcers or sores, vomiting, fever, chills, body aches, sore throat, muscle weakness, diarrhea, rash, loss of appetite, joint pain or swelling, yellow discoloration of skin and eyes, dark urine, breathing difficulty, dry cough, paleness, dizziness or fainting, unusual bruising or bleeding, seizures(fits), Consult a doctor. Do not stop using any medications without consulting a doctor.
PiroxicamNabumetone
Severe
How does the drug interact with Brexic Injection 2ml:
Coadministration of Nabumetone with Brexic Injection 2ml can increase the risk of side effects inflammation(swelling with redness and pain), bleeding, ulceration, and perforation.

How to manage the interaction:
Co-administration of Brexic Injection 2ml with Nabumetone can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without talking to a doctor.
PiroxicamMeloxicam
Severe
How does the drug interact with Brexic Injection 2ml:
Taking Brexic Injection 2ml with Meloxicam together can increase the risk of side effects inflammation(swelling with redness and pain), bleeding, ulceration, and perforation.

How to manage the interaction:
There may be a possibility of interaction between Brexic Injection 2ml and Meloxicam, but it can be taken if prescribed by a doctor. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not discontinue any medications without consulting a doctor.
PiroxicamLeflunomide
Severe
How does the drug interact with Brexic Injection 2ml:
Coadministration of Brexic Injection 2ml and Leflunomide can increase the risk of liver damage.

How to manage the interaction:
Although there is a possible interaction between Leflunomide and Brexic Injection 2ml, you can take these medicines together if prescribed by a doctor. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of hunger, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without talking to a doctor.
PiroxicamEdoxaban
Severe
How does the drug interact with Brexic Injection 2ml:
Coadministration of Brexic Injection 2ml with Edoxaban can increase the risk of bleeding.

How to manage the interaction:
Taking Brexic Injection 2ml with Edoxaban together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.
  • Acupuncture, massage, and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes, and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANALGESICS

BREXIC INJECTION 2ML Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

BREXIC INJECTION 2ML works by blocking the effect of chemical messengers (prostaglandin), thereby reducing pain, stiffness, swelling, and inflammation.

Diarrhoea might be a side-effect of BREXIC INJECTION 2ML. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Do not use BREXIC INJECTION 2ML immediately before or after bypass surgery. BREXIC INJECTION 2ML may increase the risk of heart attack or stroke. Therefore, inform your doctor if you have heart problems.

BREXIC INJECTION 2ML may be used to treat musculoskeletal pain. Musculoskeletal pain refers to the pain in the bones, muscles, ligaments, and tendon.

Drug-Drug Interactions Checker List

  • DULOXETINE
  • SERTRALINE
  • METOPROLOL
  • CELECOXIB

Disease/Condition Glossary

Osteoarthritis: It is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms of osteoarthritis include pain, stiffness, inflammation, and tenderness. The main reason for osteoarthritis is age; the older you are, the more likely you could get osteoarthritis, thus known as degenerative disease, meaning that the joints wear out as a person ages. Other reasons might include a past injury such as torn cartilage, dislocated joints, and ligament injuries.

Rheumatoid arthritis: It is an auto-immune disease (the body's immune system attacks its tissue), leading to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities, and loss of joint function.

Musculoskeletal pain: Musculoskeletal pain affects the bones, muscles, ligaments, and tendons. It can be acute or chronic, can be localised or widespread. The pain can be mild or severe enough to interfere with your daily routine. Musculoskeletal pain could occur due to arthritis, osteoporosis, fractures, dislocations, problems with the bone structure or injury to the bones, joints, tendons, muscles, and ligaments. Symptoms of musculoskeletal pain include stiffness, swelling, redness, muscle spasms or twitching, trouble moving the affected area, and soreness.

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