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Written By Divya L , PharmaD
Reviewed By Sunny S , MBBS
Non returnable*
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Whats That

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Composition :

BUTORPHANOL-2MG

Manufacturer/Marketer :

Aristo Pharmaceuticals Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Butrum 2 mg Injection

Butrum 2 mg Injection belongs to the class of 'narcotic analgesics' primarily used to treat moderate to severe pain post-surgery, muscle pain, and migraine-related headaches. Butrum 2 mg Injection is also used as an anaesthesia adjunct during surgery and early labor. Pain is a symptom triggered by the nervous system, which causes uncomfortable sensations in the body. 

Butrum 2 mg Injection contains 'Butorphanol' which works by blocking the transmission of pain signals located in the brain that controls pain, pleasure, and addictive behaviors. Butorphanol also acts as a pre-anaesthetic during surgery, antitussive (cough suppressant), and antiemetic (prevents vomiting) medication.

Use this medicine as prescribed by your doctor. Your doctor will decide the dose and duration based on the severity of your pain and response to treatment. Common side effects of Butrum 2 mg Injection include headache, dizziness, sleepiness, vomiting, nausea, and constipation. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Inform your doctor beforehand if you have liver, kidney, or heart diseases, breathing problems, mood disorders, brain-related problems, gastrointestinal disorders, underactive thyroid (hypothyroidism), drug addiction, and urination problems before starting Butrum 2 mg Injection. It is essential to let your doctor know if you are pregnant, planning to conceive, or a breastfeeding mother. Butrum 2 mg Injection causes dizziness and drowsiness, so do not drive or operate machinery until you are mentally alert. Avoid alcohol to further prevent the worsening of side effects. Butrum 2 mg Injection is not recommended for people below 18 years of age.

Uses of Butrum 2 mg Injection

Pain relief.

Directions for Use

It will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Butrum 2 mg Injection contains 'Butorphanol', an opioid analgesic that helps relieve moderate to severe pain post-surgery, muscle pain and migraine headaches. Butrum 2 mg Injection is also used as a part of anaesthesia during surgery and early labor. It helps relieve pain in various conditions like toothache, rheumatoid arthritis, and osteoarthritis. It works by acting on the opioid receptors and blocking the transmission of pain signals.

Storage

Store in a cool and dry place away from sunlight
Side effects of Butrum 2 mg Injection
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • A blocked nose can be relieved by drinking more water, which helps clear fluids.
  • Use saline nasal spray available over the counter to relieve blockage or blow harder to remove the mucus.
  • Use nasal strips that can be placed on the nose to widen nostrils and increase airflow.
  • Keep a humidifier around to moisten air at home/workplace.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

Drug Warnings

Inform your doctor if you have a history of liver, kidney or heart diseases, abdominal problems (gallbladder disease, pancreatitis), adrenal gland diseases (Addison's disease), brain disorders (fits, tumours, increased intracranial pressure), heart problems (irregular heartbeat, chest pain, a recent history of heart attack), high blood pressure and breathing problems (asthma, chronic obstructive pulmonary disease-COPD, sleep apnoea) before starting Butrum 2 mg Injection. If you have any mood disorders (toxic psychosis), spine problems (kyphoscoliosis), gastrointestinal problems (diarrhoea, paralytic ileus), personal or a family history of a substance use disorder like overuse of or addiction to drugs or alcohol, urination problems (enlarged prostate or urethral stricture) and an underactive thyroid (hypothyroidism), inform your doctor in advance before starting Butrum 2 mg Injection. Please consult your doctor if you are pregnant, planning to conceive or a breastfeeding mother. Butrum 2 mg Injection causes dizziness and drowsiness, so do not drive until you are mentally alert. Avoid alcohol to prevent the worsening of side effects further. Butrum 2 mg Injection is not recommended for anyone below 18 years of age.

Drug-Drug Interactions

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ButorphanolQuetiapine
Severe
ButorphanolZolpidem
Severe

Drug-Drug Interactions

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ButorphanolQuetiapine
Severe
How does the drug interact with Butrum 2 mg Injection:
Coadministration of quetiapine with Butrum 2 mg Injection can increase the risk of side effects such as breathing problems.

How to manage the interaction:
Co-administration of Quetiapine with Butrum 2 mg Injection can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience dizziness, sleepiness, difficulties concentrating, and judgement impairment, contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
ButorphanolZolpidem
Severe
How does the drug interact with Butrum 2 mg Injection:
Using Zolpidem together with Butrum 2 mg Injection can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Butrum 2 mg Injection and Zolpidem together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment, or reaction speed, avoid driving or operating hazardous machinery consult a doctor. Do not stop using any medications without a doctor's advice.
ButorphanolHydroxyzine
Severe
How does the drug interact with Butrum 2 mg Injection:
Using Hydroxyzine together with Butrum 2 mg Injection can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
There may be a possibility of interaction between Hydroxyzine and Butrum 2 mg Injection, but it can be taken if prescribed by a doctor. Since these medications may induce dizziness, sleepiness, trouble focusing, and impairment in judgment, response speed, and motor coordination, you should avoid driving or operating dangerous machinery until you know how they affect you. Do not discontinue any medications without consulting a doctor.
ButorphanolZiprasidone
Severe
How does the drug interact with Butrum 2 mg Injection:
Coadministration of Butrum 2 mg Injection with Ziprasidone can increase the risk of serious side effects.

How to manage the interaction:
Although there is a possible interaction between Ziprasidone and Butrum 2 mg Injection, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment. Do not discontinue any medications without consulting a doctor.
ButorphanolFosphenytoin
Severe
How does the drug interact with Butrum 2 mg Injection:
Combining Butrum 2 mg Injection with Fosphenytoin can increase the risk or severity of side effects.

How to manage the interaction:
Co-administration of Fosphenytoin with Butrum 2 mg Injection can result in an interaction, but it can be taken if your doctor has advised it. If you're having symptoms like watery eyes, runny nose, sneezing, yawning, sweating, fever, chills, restlessness, irritability, anxiety, depression, dilated pupils, trembling, fast heartbeat, twitching, loss of appetite, nausea, vomiting, diarrhoea, weight loss it's important to contact your doctor right away. Do not stop using any medications without talking to a doctor.
ButorphanolFosaprepitant
Severe
How does the drug interact with Butrum 2 mg Injection:
Coadministration of Fosaprepitant with Butrum 2 mg Injection can reduce the metabolism and increase the levels of Ivabradine in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Co-administration of Fosaprepitant with Butrum 2 mg Injection can result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms like dizziness, confusion, faintness, tiredness, irregular heartbeat, trouble breathing, feeling lightheaded, trouble focusing, or having trouble breathing make sure to call a doctor right away. Do not stop using any medications without a doctor's advice.
ButorphanolModafinil
Severe
How does the drug interact with Butrum 2 mg Injection:
Combining Butrum 2 mg Injection with Modafinil may significantly reduce the blood levels of Butrum 2 mg Injection. This may lead to poor treatment outcomes.

How to manage the interaction:
Although there is a possible interaction between Modafinil and Butrum 2 mg Injection, you can take these medicines together if prescribed by your doctor. If you're having any of these symptoms like pain, watery eyes, runny nose, sweating, fever, chills, restlessness, irritability, anxiety, fast heartbeat, twitching, loss of appetite, nausea, vomiting, diarrhea, or weight loss it's important to contact your doctor right away. Do not stop using any medications without first talking to your doctor.
ButorphanolOxazepam
Severe
How does the drug interact with Butrum 2 mg Injection:
Combining Oxazepam with Butrum 2 mg Injection can increase the risk of CNS depression.

How to manage the interaction:
Although taking Oxazepam and Butrum 2 mg Injection together can evidently cause an interaction, it can be taken if your doctor has suggested it. Contact your doctor immediately if you notice any symptoms like dizziness, drowsiness, difficulty concentrating, impaired judgment, reduced reaction speed, and motor coordination. Avoid driving or operating hazardous machinery until you know how it affects you, and avoid self-medication. Do not discontinue any medications without consulting your doctor.
ButorphanolFluconazole
Severe
How does the drug interact with Butrum 2 mg Injection:
Co-administration of Butrum 2 mg Injection with Fluconazole may increase the blood levels of Butrum 2 mg Injection and may increase side effects.

How to manage the interaction:
Although there is a possible interaction between Fluconazole and Butrum 2 mg Injection, you can take these medicines together if prescribed by a doctor. If you notice any symptoms like feeling tired, dizzy, or having trouble breathing, it's important to call a doctor right away. Do not stop using any medications without talking to a doctor.
ButorphanolItraconazole
Severe
How does the drug interact with Butrum 2 mg Injection:
Coadministration of Itraconazole with Butrum 2 mg Injection may significantly raise Butrum 2 mg Injection levels in the blood.

How to manage the interaction:
Despite the possibility of an interaction, Butrum 2 mg Injection and itraconazole can be used if a doctor orders them. Consult a doctor if you feel dizziness, fainting, confusion, extreme sleepiness, a slow heartbeat, or breathing difficulties. Never stop taking any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle exercises like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listen to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

Yes

Therapeutic Class

OPIOID ANALGESIC AND ANESTHESIA ADJUNCT

Butrum 2 mg Injection Substitute

Substitutes safety advice
  • BUTODOL 2MG INJECTION

    by Others

    79.70per tablet

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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FAQs

Butrum 2 mg Injection contains 'Butorphanol', an opioid pain reliever that blocks the transmission of pain signals by acting on specific centres of the brain. Thus Butrum 2 mg Injection reduces pain associated with various conditions like surgery pain, muscle pain, migraine headaches, arthritis pain and toothache.

Butrum 2 mg Injection may cause your blood pressure to drop upon administration of nasal spray. This may lead to fainting, light-headedness and dizziness after its use in the first hour. To prevent this from happening, remain sitting or lying down after using Butrum 2 mg Injection.

It is not recommended to suddenly stop taking Butrum 2 mg Injection since it may produce withdrawal symptoms, especially when you used Butrum 2 mg Injection for a longer time or in high doses. Please seek medical advice on how to stop taking Butrum 2 mg Injection safely. Your doctor may lower your dose slowly to prevent withdrawal symptoms.

Butrum 2 mg Injection can cause side effects like dizziness and drowsiness, hence it is advised to remain sitting or lying after taking Butrum 2 mg Injection. You are also advised not to drive or operate machinery until you are mentally alert.

Butrum 2 mg Injection may sometimes cause addiction despite its medical benefits. The risk of habit-forming or addiction is higher in people with a history of substance use disorder like overuse of drugs and alcohol. It is strictly recommended to use Butrum 2 mg Injection in the dose and duration prescribed by your doctor. Do not double the dose.

Drug-Drug Interactions Checker List

  • OXYMETAZOLINE
  • CODEINE
  • HYDROCODONE
  • ALPRAZOLAM
  • CYCLOBENZAPRINE
  • CETIRIZINE
  • DIPHENHYDRAMINE
  • KETOCONAZOLE
  • ERYTHROMYCIN
  • RITONAVIR
  • CLONAZEPAM
  • PHENYTOIN
  • METHYLENE BLUE
  • PROCARBAZINE
  • PHENELZINE
  • SELEGILINE
  • RASAGILINE
  • NALTREXONE

Special Advise

  • Let your doctor know that you are taking Butrum 2 mg Injection if you are undergoing any medical tests.
  • Monitor your blood pressure regularly since Butrum 2 mg Injection may affect your blood pressure.
  • Butrum 2 mg Injection may interfere with lab tests of amylase and lipase, hence inform your laboratory staff in advance that you are taking Butrum 2 mg Injection.

Disease/Condition Glossary

Pain: It is not a disease but a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp, it might be constant or may come and go. The tolerance level of pain might vary from person to person. Pain can be generalized (overall body aches) or localized (affecting a specific area of the body). Pain can be considered a good thing as it helps us know that something is wrong in the body and thereby helps diagnose the condition. The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures, arthritis and stomach ache. 

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