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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Composition :

BICALUTAMIDE-50MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

NPPA :

Regulated

About Calutide-50 Tablet

Calutide-50 Tablet belongs to the class of anticancer drugs called non-steroidal anti-androgens used to treat prostate cancer. Prostate cancer is prostate gland cancer (a small gland under the bladder that produces semen) found only in men. The symptoms include difficulty in urination, pain, numbness, or sexual problems.

Calutide-50 Tablet contains Bicalutamide which works by inhibiting the effects of androgens (male hormones) such as testosterone that increase the growth of prostate cancer cells. Calutide-50 Tablet prevents testosterone from binding to androgen receptors on the prostate cancer cells and starves cancer cells of testosterone. Thereby, it prevents the growth of prostate cancer cells and eventually shrinks the prostate tumor.

Take Calutide-50 Tablet with or without food as advised by your doctor and swallow whole with a glass of water. Do not crush, chew or break it. Your doctor will advise you on how often you take your tablets based on your medical condition. In some cases, you may experience weakness, skin rash, swelling and tenderness of the breast, nausea, dry skin, weight gain, hair loss, hot flushes (sudden feeling of warmth), anemia (lack of blood), reduces sex drive, constipation, depression, indigestion or dizziness. Most of these side effects of Calutide-50 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Calutide-50 Tablet or any other medicines, please tell your doctor. Calutide-50 Tablet is not recommended for women and children. Please consult a doctor if you are pregnant or breastfeeding before taking Calutide-50 Tablet . Please consult a doctor if you want to father a child before taking Calutide-50 Tablet as it may impair fertility in men. Avoid taking Calutide-50 Tablet with cisapride, astemizole, or terfenadine. Avoid direct exposure to excessive UV light or sunlight and wear protective clothing while going out in the sun as Calutide-50 Tablet may increase sunburn risk. If you have diabetes, liver, or heart problems, inform your doctor before taking Calutide-50 Tablet .

Uses of Calutide-50 Tablet

Prostate cancer

Directions for Use

Take Calutide-50 Tablet with or without food as prescribed by your doctor and swallow whole with a glass of water. Do not crush, chew or break it.

Key Benefits

Calutide-50 Tablet contains Bicalutamide, an anticancer drug used in the treatment of prostate cancer. Calutide-50 Tablet works by inhibiting the effects of androgens (male hormones) such as testosterone that increase the growth of prostate cancer cells. Calutide-50 Tablet prevents testosterone from binding to androgen receptors on the prostate cancer cells and starves cancer cells of testosterone. Thereby, it prevents the growth of prostate cancer cells and eventually shrinks the prostate tumor. Also, Calutide-50 Tablet relieves difficulty in urination. Calutide-50 Tablet can be used in combination with radiation therapy to treat prostate cancer where cancer has spread from the prostate gland to the surrounding tissues.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to Calutide-50 Tablet or any other medicines, please tell your doctor. Calutide-50 Tablet is not recommended for women and children. Please consult a doctor if you are pregnant or breastfeeding before taking Calutide-50 Tablet . You and your partner recommend using effective birth control measures while taking Calutide-50 Tablet and for 130 days after discontinuing Calutide-50 Tablet . Please consult a doctor if you want to father a child before taking Calutide-50 Tablet as it may impair fertility in men. You are advised to quit smoking as it may increase the risk of prostate cancer. Avoid taking Calutide-50 Tablet with cisapride, astemizole, or terfenadine. Regular tests are recommended to monitor liver function and if there is any severe disturbance in liver functioning, avoid taking Calutide-50 Tablet . Avoid direct exposure to excessive UV light or sunlight and wear protective clothing while going out in the sun as Calutide-50 Tablet may increase sunburn risk. If you have diabetes, liver, or heart problems, inform your doctor before taking Calutide-50 Tablet .

Diet & Lifestyle Advise

  • Include fish, soy, tomatoes, Brussels sprouts, kale, broccoli and oils containing omega-3 fatty acids such as olive oil as these foods may reduce the risk of prostate cancer.
  • Avoid grilled meat, red meat, saturated fat found in animal products, milk and dairy products as they may increase prostate cancer risk.
  • Exercise regularly to lose weight as obesity is also considered as a risk factor for prostate cancer.
  • Quit smoking to reduce the risk of prostate cancer.

Side Effects of Calutide-50 Tablet

  • Weakness
  • Skin rash
  • Swelling and tenderness of breast
  • Nausea
  • Dry skin
  • Weight gain
  • Hair loss
  • Hot flushes (sudden feeling of warmth)
  • Anaemia (lack of blood)
  • Reduced sex drive
  • Constipation
  • Depression
  • Indigestion
  • Dizziness

Habit Forming

No

Therapeutic Class

[ANTINEOPLASTIC]

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Author Details

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FAQs

Drug-Drug Interactions Checker List

  • CISAPRIDE
  • ASTEMIZOLE
  • TERFENADINE
  • PROCAINAMIDE
  • AMIODARONE
  • SOTALOL
  • QUINIDINE
  • MOXIFLOXACIN
  • METHADONE
  • WARFARIN
  • CICLOSPORIN
  • CIMETIDINE
  • KETOCONAZOLE

Special Advise

Regular blood tests are recommended to monitor changes in blood and liver functioning while taking Calutide-50 Tablet .

Disease/Condition Glossary

Prostate cancer: It is prostate gland cancer (a small gland under the bladder that produces semen) found only in men. The symptoms include difficulty in urination, pain, numbness, or sexual problems. It is the most common type of cancer in men. The cause of prostate cancer is unknown and may be caused due to exposure to certain chemicals or family history. There are certain factors that increase the risk of prostate cancer, such as a family history of prostate cancer, older age, obesity, or genetic changes.

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Alcohol

Safe if prescribed

Interaction of Calutide-50 Tablet with alcohol is unknown. Please consult a doctor before consuming alcohol while using Calutide-50 Tablet .

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Pregnancy

Consult your doctor

Calutide-50 Tablet is contraindicated in pregnant women as it is not approved for use in women. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Consult your doctor

Calutide-50 Tablet is contraindicated in breastfeeding women as it is not approved for use in women. Please consult a doctor if you are breastfeeding.

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Driving

Safe if prescribed

Calutide-50 Tablet may cause drowsiness in some people. Therefore, avoid driving if you are drowsy after taking Calutide-50 Tablet .

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Liver

Consult your doctor

Take Calutide-50 Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Consult your doctor

Calutide-50 Tablet is safe to use in patients with kidney problems if prescribed by a doctor.

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Children

Safe if prescribed

Calutide-50 Tablet is not recommended for children as the safety and effectiveness were not established.

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