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  3. Castramid 50 mg Tablet 10's

Castramid 50 mg Tablet 10's, Pack of 10 TabletS
Castramid 50 mg Tablet 10's, Pack of 10 TabletS
Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
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Whats That

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Composition :

BICALUTAMIDE-50MG

Manufacturer/Marketer :

Ipca Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Castramid 50mg Tablet

Castramid 50mg Tablet belongs to the class of anticancer drugs called non-steroidal anti-androgens used to treat prostate cancer. Prostate cancer is prostate gland cancer (a small gland under the bladder that produces semen) found only in men. The symptoms include difficulty in urination, pain, numbness, or sexual problems.

Castramid 50mg Tablet contains Bicalutamide which works by inhibiting the effects of androgens (male hormones) such as testosterone that increase the growth of prostate cancer cells. Castramid 50mg Tablet prevents testosterone from binding to androgen receptors on the prostate cancer cells and starves cancer cells of testosterone. Thereby, it prevents the growth of prostate cancer cells and eventually shrinks the prostate tumor.

Take Castramid 50mg Tablet with or without food as advised by your doctor and swallow whole with a glass of water. Do not crush, chew or break it. Your doctor will advise you on how often you take your tablets based on your medical condition. In some cases, you may experience weakness, skin rash, swelling and tenderness of the breast, nausea, dry skin, weight gain, hair loss, hot flushes (sudden feeling of warmth), anemia (lack of blood), reduces sex drive, constipation, depression, indigestion or dizziness. Most of these side effects of Castramid 50mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Castramid 50mg Tablet or any other medicines, please tell your doctor. Castramid 50mg Tablet is not recommended for women and children. Please consult a doctor if you are pregnant or breastfeeding before taking Castramid 50mg Tablet . Please consult a doctor if you want to father a child before taking Castramid 50mg Tablet as it may impair fertility in men. Avoid taking Castramid 50mg Tablet with cisapride, astemizole, or terfenadine. Avoid direct exposure to excessive UV light or sunlight and wear protective clothing while going out in the sun as Castramid 50mg Tablet may increase sunburn risk. If you have diabetes, liver, or heart problems, inform your doctor before taking Castramid 50mg Tablet .

Uses of Castramid 50mg Tablet

Prostate cancer

Directions for Use

Take Castramid 50mg Tablet with or without food as prescribed by your doctor and swallow whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

Castramid 50mg Tablet contains Bicalutamide, an anticancer drug used in the treatment of prostate cancer. Castramid 50mg Tablet works by inhibiting the effects of androgens (male hormones) such as testosterone that increase the growth of prostate cancer cells. Castramid 50mg Tablet prevents testosterone from binding to androgen receptors on the prostate cancer cells and starves cancer cells of testosterone. Thereby, it prevents the growth of prostate cancer cells and eventually shrinks the prostate tumor. Also, Castramid 50mg Tablet relieves difficulty in urination. Castramid 50mg Tablet can be used in combination with radiation therapy to treat prostate cancer where cancer has spread from the prostate gland to the surrounding tissues.

Storage

Store in a cool and dry place away from sunlight
Side effects of Castramid 50 mg Tablet
  • Consult a doctor to identify the cause and receive appropriate treatment.
  • Your doctor may prescribe or adjust medications to manage pain-induced side effects.
  • Applying heat or cold packs to the affected area might help reduce inflammation and relieve discomfort.
  • Massage therapy helps to relax muscles, boost circulation, and reduce pain.
  • Manage stress using relaxation techniques like meditation, deep breathing, or progressive muscle relaxation.
  • Inform your doctor if you experience sudden severe pain that worsens over time.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Talk to your doctor to know the cause, severity and appropriate treatment options.
  • Try pain relievers like ibuprofen or naproxen to relieve mild pelvic pain.
  • Consider pelvic floor exercises as it helps to strengthen muscles in the pelvic region and relieve pain.
  • Try relaxation techniques like deep breathing, meditation or gentle stretching.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Drug Warnings

If you are allergic to Castramid 50mg Tablet or any other medicines, please tell your doctor. Castramid 50mg Tablet is not recommended for women and children. Please consult a doctor if you are pregnant or breastfeeding before taking Castramid 50mg Tablet . You and your partner recommend using effective birth control measures while taking Castramid 50mg Tablet and for 130 days after discontinuing Castramid 50mg Tablet . Please consult a doctor if you want to father a child before taking Castramid 50mg Tablet as it may impair fertility in men. You are advised to quit smoking as it may increase the risk of prostate cancer. Avoid taking Castramid 50mg Tablet with cisapride, astemizole, or terfenadine. Regular tests are recommended to monitor liver function and if there is any severe disturbance in liver functioning, avoid taking Castramid 50mg Tablet . Avoid direct exposure to excessive UV light or sunlight and wear protective clothing while going out in the sun as Castramid 50mg Tablet may increase sunburn risk. If you have diabetes, liver, or heart problems, inform your doctor before taking Castramid 50mg Tablet .

Drug-Drug Interactions

verifiedApollotooltip
BicalutamideDronedarone
Critical
BicalutamideHalofantrine
Critical

Drug-Drug Interactions

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BicalutamideDronedarone
Critical
How does the drug interact with Castramid 50 mg Tablet:
When Castramid 50 mg Tablet is taken with Dronedarone, can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Castramid 50 mg Tablet with Dronedarone is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
BicalutamideHalofantrine
Critical
How does the drug interact with Castramid 50 mg Tablet:
Taking Castramid 50 mg Tablet with Halofantrine can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Castramid 50 mg Tablet with Halofantrine is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
BicalutamidePimozide
Critical
How does the drug interact with Castramid 50 mg Tablet:
When Castramid 50 mg Tablet is taken with Pimozide, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Castramid 50 mg Tablet with Pimozide is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
BicalutamideThioridazine
Critical
How does the drug interact with Castramid 50 mg Tablet:
Taking Castramid 50 mg Tablet with Thioridazine can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Castramid 50 mg Tablet with Thioridazine is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
BicalutamideSaquinavir
Critical
How does the drug interact with Castramid 50 mg Tablet:
When Castramid 50 mg Tablet is taken with Saquinavir, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Castramid 50 mg Tablet with Saquinavir is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
BicalutamideMesoridazine
Critical
How does the drug interact with Castramid 50 mg Tablet:
Taking Castramid 50 mg Tablet with Mesoridazine can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Castramid 50 mg Tablet with Mesoridazine is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
BicalutamideZiprasidone
Critical
How does the drug interact with Castramid 50 mg Tablet:
Taking Castramid 50 mg Tablet and Ziprasidone can increase the risk of an irregular heart rhythm

How to manage the interaction:
Taking Castramid 50 mg Tablet with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
BicalutamideBedaquiline
Severe
How does the drug interact with Castramid 50 mg Tablet:
Co-administration of Castramid 50 mg Tablet and Bedaquiline together can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Castramid 50 mg Tablet and Bedaquiline together can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, shortness of breath, or rapid heartbeat, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
BicalutamideSotalol
Severe
How does the drug interact with Castramid 50 mg Tablet:
Co-administration of Castramid 50 mg Tablet and Sotalol together can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Castramid 50 mg Tablet and Sotalol together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor immediately. Do not stop using any medications without consulting a doctor.
BicalutamideVandetanib
Severe
How does the drug interact with Castramid 50 mg Tablet:
Co-administration of Castramid 50 mg Tablet and Vandetanib together can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Castramid 50 mg Tablet and Vandetanib together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include fish, soy, tomatoes, Brussels sprouts, kale, broccoli and oils containing omega-3 fatty acids such as olive oil as these foods may reduce the risk of prostate cancer.
  • Avoid grilled meat, red meat, saturated fat found in animal products, milk and dairy products as they may increase prostate cancer risk.
  • Exercise regularly to lose weight as obesity is also considered as a risk factor for prostate cancer.
  • Quit smoking to reduce the risk of prostate cancer.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Castramid 50mg Tablet Substitute

Substitutes safety advice

Product Substitutes

Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 8, 2025 | 9:34 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Castramid 50mg Tablet contains Bicalutamide, an anticancer drug that works by inhibiting the effects of androgens (male hormones) such as testosterone and reduces or prevents the growth of prostate cancer cells and eventually shrink the prostate tumour.

You are not recommended to take Castramid 50mg Tablet with anti-allergic drugs such as terfenadine or astemizole. It may increase the levels of terfenadine or astemizole in blood and cause adverse effects as severe irregular heartbeat. However, please consult a doctor before taking Castramid 50mg Tablet with other medicines.

Castramid 50mg Tablet may cause infertility or a period of subfertility (delay in conceiving) in men. Therefore, if you want to father a child, please discuss with your doctor before taking Castramid 50mg Tablet .

Castramid 50mg Tablet should be used with caution in diabetic patients as it may increase the risk of high blood sugar levels. Therefore, regular monitoring of blood sugar levels is recommended while taking Castramid 50mg Tablet and inform your doctor if you have diabetes before taking Castramid 50mg Tablet .

Castramid 50mg Tablet is not recommended for patients suffering from heart rhythm problems such as arrhythmia (irregular heartbeat) as it may increase the risk of heart rhythm problems. Therefore, inform your doctor if you have any heart problems before taking Castramid 50mg Tablet .

Castramid 50mg Tablet increase skin sensitivity to the sun and make sunburn more easily. Therefore, avoid direct exposure to excessive UV-light or sunlight, wear protective clothing and use a sunscreen while going out in the sun.

Drug-Drug Interactions Checker List

  • CISAPRIDE
  • ASTEMIZOLE
  • TERFENADINE
  • PROCAINAMIDE
  • AMIODARONE
  • SOTALOL
  • QUINIDINE
  • MOXIFLOXACIN
  • METHADONE
  • WARFARIN
  • CICLOSPORIN
  • CIMETIDINE
  • KETOCONAZOLE

Special Advise

Regular blood tests are recommended to monitor changes in blood and liver functioning while taking Castramid 50mg Tablet .

Disease/Condition Glossary

Prostate cancer: It is prostate gland cancer (a small gland under the bladder that produces semen) found only in men. The symptoms include difficulty in urination, pain, numbness, or sexual problems. It is the most common type of cancer in men. The cause of prostate cancer is unknown and may be caused due to exposure to certain chemicals or family history. There are certain factors that increase the risk of prostate cancer, such as a family history of prostate cancer, older age, obesity, or genetic changes.

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