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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Whats That

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Composition

MESNA-200MG

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Cancena Injection 2 ml

Cancena Injection 2 ml belongs to a class of medication known as 'cytoprotectant' primarily used to prevent Hemorrhagic cystitis (a condition that causes bleeding in the urine due to the effect of anticancer agents (Ifosfamide). Our bodies degrade the anticancer drug (ifosfamide) to generate a compound (acrolein) that can injure and irritate the bladder. Cancena Injection 2 ml decreases the risk of bladder irritation and bleeding caused by other anti-cancer drugs.

Cancena Injection 2 ml contains 'Mesna', a chemo-protectant medicine that alters the breakdown of anti-cancer agents (Ifosfamide) found in the urine, making it less toxic. In addition, it binds to other urotoxic metabolites and inhibits their effects on the bladder.

Cancena Injection 2 ml will be administered to your vein by a trained healthcare professional; hence, do not self-administer. In some cases, this medicine may cause certain side effects such as nausea, vomiting, headache, flushing (sense of warmth in the face, ears, neck, and trunk), lethargy, rash, diarrhea, light-headedness, abdominal pain, flu-like symptoms, fever, and injection site reactions. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Cancena Injection 2 ml is not recommended if you are allergic to it or any of its ingredients. An effective birth control measure should be taken to avoid pregnancy in women of a mother-bearing you’re your doctor may suggest regular urine and blood test while receiving Cancena Injection 2 ml to monitor your CBC (blood cell count). Cancena Injection 2 ml is not indicated for use in hematuria due to other underlying pathological conditions like thrombocytopenia. It is advised to drink at least 1-2 litres of fluid daily while receiving Cancena Injection 2 ml. This medicine should be avoided in pregnant and breastfeeding populations due to serious side effects; hence inform your doctor before administration.

Uses of Cancena Injection 2 ml

Ifosfamide-induced hemorrhagic cystitis. 

Directions for Use

Cancena Injection 2 ml will be administered by a healthcare professional. Do not self-administer.

Medicinal Benefits

Cancena Injection 2 ml belongs to a class of medication known as 'chemoprotectant' primarily used to prevent bleeding into the urine by a particular anticancer medicine known as ifosfamide (ifosfamide-induced hemorrhagic cystitis). It also reduces the risk of inflammation and bleeding in the bladder by receiving anti-cancer medication. It contains Mesna, which works by reacting chemically with the urotoxic ifosfamide (anti-cancer medicines) metabolites, resulting in their detoxification. In addition, it binds to other urotoxic metabolites and inhibits their effects on the bladder.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Cancena Injection 2 ml

  • Nausea
  • Headache
  • Flushing (sense of warmth in the face, ears, neck and trunk)
  • Lethargy
  • Rash
  • Diarrhea
  • Lightheadedness
  • Abdominal pain
  • Flu-like symptoms
  • Fever
  • Injection site reactions

Drug Warnings

Do not take this injection if you are allergic to Cancena Injection 2 ml or any of its ingredients. An effective birth control method should be used to avoid pregnancy in women of childbearing age. Maintain a three-month gap between your last dose of Cancena Injection 2 ml and your next pregnancy. Regular urine and blood test should be done while receiving Cancena Injection 2 ml to monitor your CBC (blood cell count). It is not indicated for use in hematuria due to other underlying pathological conditions like thrombocytopenia. This medicine is known to cause blurry vision and dizziness, so do not drive or operate machinery. 

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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Diet & Lifestyle Advise

  • Empty your bladder frequently in the first 24 hours of chemotherapy (cancer treatment). If any pain occurs during urination, let your doctor know it.
  • Nausea can occur as a side effect of chemotherapy. Eat small and frequent meals to avoid it, or you can take any anti-nausea medicine.
  • Sleep at least 8 hours a day and take plenty of rest.
  • Maintain good nutrition. Eat home-cooked and freshly prepared food. Avoid junk, oily and spicy food.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS

Cancena Injection 2 ml Substitute

Substitutes safety advice
  • Mistabron Respirator Solution 3 ml

    by Others

    74.10per tablet
  • Mesna 200 mg Injection 2 ml

    by AYUR

    14.65per tablet
  • Uromixtexan 200 mg Injection 1's

    by Others

    31.17per tablet

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • WARFARIN
  • DICUMAROL
  • ANISINDIONE

Special Advise

  • Regular blood and urine test are required while receiving Cancena Injection 2 ml.
  • Cancena Injection 2 ml may interfere with enzymatic creatinine phosphokinase (CPK) activity tests that use a thiol compound (N-acetylcysteine) for CPK reactivation. This may result in a falsely low CPK level. Inform your doctor about the use of Cancena Injection 2 ml.
  • Cancena Injection 2 ml may interfere with a certain laboratory test (for urinary ketones), possibly causing false test results. Hence inform your doctor or laboratory personnel about the use of this medicine.

Disease/Condition Glossary

Ifosfamide-induced Hemorrhagic cystitis: It is a condition that causes bleeding in the urine due to the effect of anticancer agents (Ifosfamide). It occurs when an individual undergoes planned chemotherapy (for cancer treatment). During chemotherapy, an anticancer medication called 'ifosfamide' causes inflammation and bleeding of the bladder, which is passed into the urine. The colour of urine may vary from pink to red in colour.  

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