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Written By Divya L , PharmaD
Reviewed By Sunny S , MBBS
Non returnable*
COD available

Online payment accepted

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Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Canex 400 mg Tablet 1's

Canex 400 mg Tablet 1's belongs to the class of medicines called 'antifungals' used to treat a broad range of infections caused due to fungi and yeast. A fungal infection is caused when a fungus invades and affects any part of the body, including the mouth, throat, oesophagus, lungs, bladder, genital area, and blood.

Canex 400 mg Tablet 1's contains ‘Fluconazole’ that kills or prevents fungi or yeast by inhibiting an enzyme in fungi responsible for its normal fat metabolism, which interferes with the formation of the fungal cell membrane. As a result, fungal or yeast cells get killed or their growth is minimized.

Take this medicine as prescribed by your doctor. Canex 400 mg Tablet 1's has common side effects like headache, diarrhoea, nausea, stomach upset, dizziness, stomach pain, and altered food tastes. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Inform your doctor if you are allergic to Canex 400 mg Tablet 1's or any of its components. Let your doctor know if you have any liver, kidney or heart problems before starting Canex 400 mg Tablet 1's. Pregnant and breastfeeding women should consult their doctor before starting Canex 400 mg Tablet 1's. It is advised to avoid alcohol intake while using Canex 400 mg Tablet 1's to prevent any undesirable effects.

Uses of Canex 400 mg Tablet 1's

Fungal infections.

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.Oral liquid: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Medicinal Benefits

Canex 400 mg Tablet 1's works by killing the fungus/yeast and preventing its growth by inhibiting the fungal cell membrane formation. It is used to treat various fungal or yeast infections, such as vaginal candidiasis, oropharyngeal candidiasis (thrush, oral thrush), esophageal candidiasis (candida esophagitis), candida infections (urinary tract infections, peritonitis), and cryptococcal meningitis. Besides this, Canex 400 mg Tablet 1's is also used to prevent candidiasis and coccidioidomycosis in patients who receive cancer or radiation treatment while undergoing bone marrow transplantation. Canex 400 mg Tablet 1's is effective in treating soft tissue and pulmonary infections when compared to other azole antifungal drugs.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Canex 400 mg Tablet 1's

  • Headache
  • Diarrhoea
  • Nausea
  • Stomach upset
  • Dizziness
  • Stomach pain
  • Altered food tastes

Drug Warnings

Please inform your doctor if you use any prescription, or non-prescription medicines, including vitamin and herbal supplements before using Canex 400 mg Tablet 1's. Do not use Canex 400 mg Tablet 1's if you are allergic to Canex 400 mg Tablet 1's or any of its components. Let your doctor know if you have any liver, kidney, or heart problems before starting Canex 400 mg Tablet 1's. This medicine may not be suitable for some people who have a weakened immune system, diabetes, cancer, or low blood magnesium or potassium levels; however, please seek medical advice. Pregnant or lactating women should consult the doctor before taking the Canex 400 mg Tablet 1's. Do not drive or operate machinery if you experience dizziness or other side effects that may affect your mental ability to drive. Avoid alcohol consumption along with Canex 400 mg Tablet 1's to avoid undesirable effects 

Drug-Drug Interactions

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FluconazoleErythromycin
Critical
FluconazoleLomitapide
Critical

Drug-Drug Interactions

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FluconazoleErythromycin
Critical
How does the drug interact with Canex 400 mg Tablet:
Taking Canex 400 mg Tablet with Erythromycin can increase the risk of heart rhythm problems.

How to manage the interaction:
Taking Canex 400 mg Tablet with Erythromycin together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
FluconazoleLomitapide
Critical
How does the drug interact with Canex 400 mg Tablet:
When Lomitapide is taken with Canex 400 mg Tablet, may increase the blood levels of lomitapide.

How to manage the interaction:
Taking Canex 400 mg Tablet with Lomitapide together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
FluconazoleAstemizole
Critical
How does the drug interact with Canex 400 mg Tablet:
When Astemizole is taken with Canex 400 mg Tablet, the body's ability to break down Astemizole may be reduced.

How to manage the interaction:
Taking Canex 400 mg Tablet with Astemizole can lead to an interaction, please consult a doctor before taking it. Do not discontinue the medications without of consulting a doctor.
FluconazoleEliglustat
Critical
How does the drug interact with Canex 400 mg Tablet:
When Eliglustat and Canex 400 mg Tablet are taken together, Canex 400 mg Tablet can significantly increase the blood levels of eliglustat.

How to manage the interaction:
Taking Canex 400 mg Tablet with Eliglustat together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, slow heart rate, weak pulse, or heart palpitations. Do not discontinue any medications without consulting a doctor.
FluconazoleEscitalopram
Severe
How does the drug interact with Canex 400 mg Tablet:
Taking Canex 400 mg Tablet with Escitalopram can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction, Canex 400 mg Tablet can be taken with Escitalopram if prescribed by the doctor. Consult the doctor if you experience sudden lightheadedness, dizziness, shortness of breath, fainting, or heart palpitations during treatment with these medications. Do not discontinue the medications without a doctor's advice.
FluconazoleGlimepiride
Severe
How does the drug interact with Canex 400 mg Tablet:
Co-administration of Canex 400 mg Tablet may increase the blood levels and effects of Glimepiride may cause low blood glucose.

How to manage the interaction:
Although there is a possible interaction, glimepiride can be taken with Canex 400 mg Tablet if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar like headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
FluconazoleRuxolitinib
Severe
How does the drug interact with Canex 400 mg Tablet:
Co-administration of Ruxolitinib with Canex 400 mg Tablet may increase the blood levels of Ruxolitinib.

How to manage the interaction:
Although there is a possible interaction, Canex 400 mg Tablet can be taken with Ruxolitinib if prescribed by the doctor. Consult the doctor if you experience signs and symptoms such as paleness, tiredness, dizziness, fainting, unusual bleeding or bruising, fever, chills, sore throat, body aches, or other flu-like symptoms. Do not discontinue the medications without consulting a doctor.
FluconazoleArsenic trioxide
Severe
How does the drug interact with Canex 400 mg Tablet:
Taking Canex 400 mg Tablet with Arsenic trioxide can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Arsenic trioxide with Canex 400 mg Tablet together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you experience any symptoms like an irregular heart rhythm, dizziness, fainting, or difficulty breathing, it is important to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
FluconazoleAcalabrutinib
Severe
How does the drug interact with Canex 400 mg Tablet:
When Acalabrutinib is taken with Canex 400 mg Tablet, can significantly increase the blood levels of Acalabrutinib.

How to manage the interaction:
Co-administration of Canex 400 mg Tablet with Acalabrutinib can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms - feeling sick, throwing up, having diarrhea, stomach pain, bleeding, heart problems, feeling weak, dizzy, or tired, having a fever, sore throat, muscle pain, trouble breathing, losing weight, or experiencing pain, bleeding, or bruising, make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
FluconazoleTolazamide
Severe
How does the drug interact with Canex 400 mg Tablet:
When Tolazamide is taken with Canex 400 mg Tablet, may increase the blood levels and effects of Tolazamide.

How to manage the interaction:
Although taking Tolazamide and Canex 400 mg Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. It's important to talk to a doctor about any medications you are taking to avoid any potential risks or side effects. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid frequent douching to maintain the natural moisture in the vagina.
  • Use mild soap while taking baths and prefer warm baths.
  • Avoid harsh products on your skin.
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Avoid or limit the intake of alcohol and caffeine.
  • It is advisable to follow a candida diet during yeast infections. This diet excludes sugar, gluten, certain dairy products, and alcohol, and includes low-sugar fruits, non-starchy vegetables, and gluten-free foods.
  • A very-high sugar or high-carbohydrate diet may increase the count of Candida in some people.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS

Canex 400 mg Tablet 1's Substitute

Substitutes safety advice
  • AF-400 Tablet 1's

    by Others

    25.70per tablet
  • Zocon 400 Tablet 1's

    by Others

    29.70per tablet
  • Flutas-400 Tablet 1's

    by Others

    29.70per tablet
  • ONECAN 400MG TABLET, 2's

    by Others

    29.95per tablet
  • Flucos 400 Tablet 1's

    by Others

    29.70per tablet

Author Details

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Drug-Diseases Interactions

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FLUCONAZOLE-400MGOther diseases of liver
Severe
FLUCONAZOLE-400MGOther cardiac arrhythmias
Moderate

Drug-Diseases Interactions

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FLUCONAZOLE-400MGOther diseases of liver
Severe
How does the disease interact with Canex 400 mg Tablet:
Hepatotoxicity has only sometimes been linked to the usage of Canex 400 mg Tablet. There have been cases of reversible idiosyncratic hepatitis, cholestasis, and deadly fulminant hepatic failure; the latter generally affects people with substantial underlying medical disorders who are also taking several concurrent drugs. Patients with pre-existing hepatic problems should have periodic liver function tests done, especially during prolonged medication. If liver enzyme levels continue to rise or worsen, treatment should be stopped.

How to manage the interaction:
In patients with preexisting liver abnormalities, particularly during prolonged therapy, liver function tests should be done regularly. Treatment should be withdrawn if persistent elevations or worsening of liver enzyme levels occur.
FLUCONAZOLE-400MGOther cardiac arrhythmias
Moderate
How does the disease interact with Canex 400 mg Tablet:
The QT interval on the ECG has been shown to be prolonged by some azole antifungals. During postmarketing experience, there have been a few isolated incidences of QT prolongation and torsade de pointes; these reports typically involved critically ill patients with a number of complicating risk factors, including structural cardiac disease, electrolyte problems, and concurrent medicines. Patients with illnesses that could cause proarrhythmic symptoms should take these medications cautiously. It is best to avoid using drugs that could potentially enhance the risk of cardiotoxicity concurrently.

How to manage the interaction:
It should be administered with caution to patients with heart problems. Concomitant use with other medications that have potential to increase the risk of cardiotoxicity should be avoided.
FLUCONAZOLE-400MGCare involving dialysis
Moderate
How does the disease interact with Canex 400 mg Tablet:
Hemodialysis effectively removes Canex 400 mg Tablet from the body. Following three hours of dialysis, it has been demonstrated that plasma levels of Canex 400 mg Tablet decrease by 50%. After hemodialysis, Canex 400 mg Tablet should be taken.

How to manage the interaction:
Canex 400 mg Tablet should be administered after hemodialysis.

Drug-Drug Interactions Checker List

  • PIMOZIDE
  • QUETIAPINE
  • ERYTHROMYCIN
  • ERGOTAMINE
  • AMIODARONE
  • WARFARIN
  • CARBAMAZEPINE
  • LOSARTAN
  • METFORMIN
  • REBOXETINE

Special Advise

It is advised to reach out to your doctor if the infection symptoms persist or worsen after two weeks of treatment. 

Disease/Condition Glossary

Fungal infection occurs when a fungus enters, infects, and multiplies in the body. Fungi can live in water, soil, air, and plants. Fungi affect any part of the body, including the mouth, throat, oesophagus, lungs, bladder, genital area, and blood. Mild fungal skin infections are common and can cause rashes. Fungal infections affecting body organs like the lungs can cause flu or tuberculosis. Some fungal diseases like cryptococcal meningitis and blood infections can be fatal. A few common fungal infections are yeast infections that affect the genital area, oesophagus, and urinary tract caused by the species Candida. 

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