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Written By Bayyarapu Mahesh Kumar , M Pharmacy
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Composition :

CARBOPLATIN-450MG

Manufacturer/Marketer :

Pharmacia & Upjohn India Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About CARBOPLATIN 450MG INJECTION

CARBOPLATIN 450MG INJECTION belongs to a group of anti-cancer medicines used for the treatment of ovarian cancer and small-cell lung cancer. It may sometimes be used to treat other cancers. Cancer forms in tissues of the ovary (one of a pair of female reproductive glands in which the ova, or eggs, are formed). Small-cell lung cancer is a disease in which malignant (cancer) cells form in the tissues of the lung.

CARBOPLATIN 450MG INJECTION contains 'Carboplatin'. Carboplatin acts by penetrating the cell wall and binding to the cell's DNA, stopping the cell from naturally dividing and functioning, ultimately destroying the cell. These medicines target cancer cells because they often affect rapidly dividing cells.

CARBOPLATIN 450MG INJECTION is prescribed by a doctor experienced in the use of medications to treat cancer. It is administered by a healthcare professional as an injection. You may experience nausea, diarrhoea, vomiting, thrombocytopenia (a low platelet count), peripheral neuropathy (nerves malfunction), nephrotoxicity at high doses and electrolyte disturbances. Most of these side effects of CARBOPLATIN 450MG INJECTION do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

To treat your condition effectually, continue taking CARBOPLATIN 450MG INJECTION for as long as your doctor has prescribed. Do not stop the CARBOPLATIN 450MG INJECTION midway. Talk to your doctor before taking CARBOPLATIN 450MG INJECTION if you have severe allergic reactions to CARBOPLATIN 450MG INJECTION or other platinum-containing compounds or if you are suffering from peripheral neuropathy (nerves malfunction), hypotension, cardiac disorders, severe lung problems, pulmonary disorders, posterior reversible encephalopathy syndrome disorders, gastrointestinal disorders, thrombocytopenia (a low platelet count), neutropenia (low white blood cell count), tumour lysis syndrome (metabolic abnormalities that can occur as a complication during the treatment of cancer), hepatic disorders. CARBOPLATIN 450MG INJECTION should not be employed in patients with severe bone marrow depression or significant bleeding. Avoid taking CARBOPLATIN 450MG INJECTION if you are pregnant or breastfeeding because this CARBOPLATIN 450MG INJECTION can cause harmful effects on the unborn baby. Both women and men using this CARBOPLATIN 450MG INJECTION should use birth control to avoid pregnancy.

Uses of CARBOPLATIN 450MG INJECTION

Ovarian cancer and Small cell lung cancer

Directions for Use

Parenteral: CARBOPLATIN 450MG INJECTION will be administered by a qualified healthcare professional. Kindly do not self-administer.

Medicinal Benefits

CARBOPLATIN 450MG INJECTION contains 'Carboplatin' which belongs to a group of anti-cancer medicines used to treat ovarian cancer and small cell lung cancer. It works by damaging the genetic material (DNA) of the cancer cells, which stops their growth and multiplication. It can be used alone or with other chemotherapy drugs depending on your cancer type.

Storage

Store in a cool and dry place away from sunlight
Side effects of Carboplatin 450mg Injection 45ml
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in white blood cells which may lead to impaired immunity.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Limit the intake of alcohol consumption.
  • Get vaccinated against hepatitis B and C.
  • Maintain a healthy weight through diet and exercise.
  • Eat healthy diet containing fruits, vegetables, whole grains, and lean proteins.
  • Include vitamin D in your diet.
  • Apply a hot/cold pack to the affected area.
  • Doing gentle exercises can help cope with pain by stretching muscles.
  • Get enough sleep. It helps enhance mood and lower pain sensitivity.
  • Avoid alcohol, smoking and tobacco as they can increase pain.
  • Follow a well-balanced meal.
  • Meditation and massages may also help with pain.

Drug Warnings

CARBOPLATIN 450MG INJECTION should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking CARBOPLATIN 450MG INJECTION. To treat your condition effectually, continue taking CARBOPLATIN 450MG INJECTION for as long as your doctor has prescribed. Do not stop the CARBOPLATIN 450MG INJECTION midway. Talk to your doctor before taking CARBOPLATIN 450MG INJECTION if you have severe allergic reactions to CARBOPLATIN 450MG INJECTION or other platinum-containing compounds or if you are suffering from peripheral neuropathy (nerves malfunction), hypotension, cardiac disorders, severe lung problems, pulmonary disorders, posterior reversible encephalopathy syndrome disorders, gastrointestinal disorders, thrombocytopenia (a low platelet count), neutropenia (low white blood cell count), tumour lysis syndrome (metabolic abnormalities that can occur as a complication during the treatment of cancer), hepatic disorders. CARBOPLATIN 450MG INJECTION should not be employed in patients with severe bone marrow depression or significant bleeding. Avoid taking CARBOPLATIN 450MG INJECTION if you are pregnant or breastfeeding because this CARBOPLATIN 450MG INJECTION can cause harmful effects on the unborn baby. Both women and men using this CARBOPLATIN 450MG INJECTION should use birth control to avoid pregnancy. Peripheral blood counts should be frequently monitored during CARBOPLATIN 450MG INJECTION treatment and appropriate until recovery is achieved.

Drug-Drug Interactions

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CarboplatinGolimumab
Severe

Drug-Drug Interactions

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How does the drug interact with Carboplatin 450mg Injection 45ml 450mg Injection 45ml:
Co-administration of Sorafenib with Carboplatin 450mg Injection 45ml can increase the risk or severity of serious side effects.

How to manage the interaction:
Taking Sorafenib with Carboplatin 450mg Injection 45ml together is not recommended as it can cause an interaction, consult a doctor before taking it. However if you experience any unusual symptoms, consult the doctor. Do not stop using any medications without consulting a doctor.
CarboplatinGolimumab
Severe
How does the drug interact with Carboplatin 450mg Injection 45ml 450mg Injection 45ml:
Using Carboplatin 450mg Injection 45ml with Golimumab can increase the risk of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between Carboplatin 450mg Injection 45ml and Golimumab, you can take these medicines together if prescribed by your doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Carboplatin 450mg Injection 45ml 450mg Injection 45ml:
Using Carboplatin 450mg Injection 45ml with Fingolimod can increase the risk of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between Carboplatin 450mg Injection 45ml and Fingolimod, you can take these medicines together if prescribed by your doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Carboplatin 450mg Injection 45ml 450mg Injection 45ml:
Coadministration of baricitinib and Carboplatin 450mg Injection 45ml can raise your risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Carboplatin 450mg Injection 45ml if prescribed by the doctor. However, if you experience fever, chills, diarrhoea, sore throat, muscular aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Carboplatin 450mg Injection 45ml 450mg Injection 45ml:
Co-administration of Carboplatin 450mg Injection 45ml with tofacitinib can increase the risk of serous infections.

How to manage the interaction:
Although there is an interaction, Carboplatin 450mg Injection 45ml can be taken with tofacitinib if prescribed by the doctor. However, If you experience fever, chills, diarrhea, sore throat, muscular pains, breathing difficulty, blood in phlegm(mucous secretion), red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Carboplatin 450mg Injection 45ml 450mg Injection 45ml:
When Carboplatin 450mg Injection 45ml is used with topotecan, it may increase the risk of side effects.

How to manage the interaction:
Co-administration of Carboplatin 450mg Injection 45ml with clozapine can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Carboplatin 450mg Injection 45ml 450mg Injection 45ml:
Taking Carboplatin 450mg Injection 45ml with etanercept may increase the risk of serious infections.

How to manage the interaction:
Co-administration of Carboplatin 450mg Injection 45ml and etanercept can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm (mucous secretion), red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
CarboplatinCertolizumab
Severe
How does the drug interact with Carboplatin 450mg Injection 45ml 450mg Injection 45ml:
Using Carboplatin 450mg Injection 45ml with Certolizumab can increase the risk of developing serious infections.

How to manage the interaction:
Taking Carboplatin 450mg Injection 45ml with Certolizumab together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
CarboplatinPalifermin
Severe
How does the drug interact with Carboplatin 450mg Injection 45ml 450mg Injection 45ml:
When Palifermin is used with Carboplatin 450mg Injection 45ml, may increase the risk or severity of mouth ulcers.

How to manage the interaction:
Co-administration of Carboplatin 450mg Injection 45ml with Palifermin can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have painful mouth ulcers, contact the doctor right away. It is advised to take Palifermin at least after 24 hours of stopping Carboplatin 450mg Injection 45ml. Do not stop using any medications without a doctor's advice.
How does the drug interact with Carboplatin 450mg Injection 45ml 450mg Injection 45ml:
Taking cidofovir with Carboplatin 450mg Injection 45ml can increase the risk of kidney problems.

How to manage the interaction:
Although taking Carboplatin 450mg Injection 45ml and cidofovir together can possibly cause an interaction, it can be taken if your doctor has suggested it. However, if you experience loss of hunger, increased or decreased urination, swelling, shortness of breath, bone pain, muscle cramps, irregular heart rhythm, consult a doctor immediately. It is advised to wait at least for 7 days after stopping Carboplatin 450mg Injection 45ml, before taking Cidofovir. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs in your diet.
  • Get optimal sleep; rest well.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Drug-Diseases Interactions

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CARBOPLATIN-450MGOther and unspecified infectious diseases
Moderate
CARBOPLATIN-450MGOther disorders of kidney and ureter, not elsewhere classified
Moderate

Drug-Diseases Interactions

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CARBOPLATIN-450MGOther and unspecified infectious diseases
Moderate
How does the disease interact with Carboplatin 450mg Injection 45ml 450mg Injection 45ml:
Antineoplastic drugs regularly can, to variable degrees, promote myelosuppression due to their cytotoxic effects on rapidly growing tissues.

How to manage the interaction:
If you experience any signs or symptoms suggesting infection such as fever, sore throat, or local infection during antineoplastic therapy, immediately consult your doctor. Close clinical monitoring of hematopoietic function is recommended.
CARBOPLATIN-450MGOther disorders of kidney and ureter, not elsewhere classified
Moderate
How does the disease interact with Carboplatin 450mg Injection 45ml 450mg Injection 45ml:
The kidney is the main organ used to remove Carboplatin 450mg Injection 45ml. Patients with a creatinine clearance of less than 60 mL/min had lower total body and renal clearance of Carboplatin 450mg Injection 45ml.

How to manage the interaction:
If you have any kidney related problems, do not forget to mention it to your doctor, a close monitoring is required.
CARBOPLATIN-450MGHaemorrhage, not elsewhere classified
Mild
How does the disease interact with Carboplatin 450mg Injection 45ml 450mg Injection 45ml:
Patients who have substantial bleeding should not use Carboplatin 450mg Injection 45ml. Both severe myelosuppression and dose-dependent thrombocytopenia are brought on by Carboplatin 450mg Injection 45ml.

How to manage the interaction:
The use of Carboplatin 450mg Injection 45ml is not advisable if you have significant bleeding. If you experience any signs or symptoms suggesting bleeding such as petechiae, purpura, epistaxis, hemoptysis, hematuria, and melena, consult your doctor. Close clinical monitoring of hematopoietic function is recommended.

FAQs

CARBOPLATIN 450MG INJECTION contains 'Carboplatin'. Carboplatin works by breaching the cellular wall and binding to the cell’s DNA, preventing the cell from dividing and functioning normally, which eventually kills the cell.

Yes, CARBOPLATIN 450MG INJECTION can cause low neutrophils levels, a type of white blood cells that help fight infections. If your white blood cells become low, you can be at higher risk for infections. Tell your doctor if you develop a fever or believe you have an infection.

CARBOPLATIN 450MG INJECTION should be administered under the supervision of a qualified physician experienced in the use of cancer chemotherapeutic agents.

Before you receive treatment with CARBOPLATIN 450MG INJECTION, tell your doctor about all of your medical conditions. You should not receive CARBOPLATIN 450MG INJECTION if you are allergic to carboplatin or any contents in CARBOPLATIN 450MG INJECTION. It should not be employed in patients with severe bone marrow depression or significant bleeding.

If not given an inappropriate dose, CARBOPLATIN 450MG INJECTION can cause toxic effects, although not everyone gets it. So, CARBOPLATIN 450MG INJECTION is prescribed by a doctor experienced in the use of medications to treat cancer only.

Avoid taking CARBOPLATIN 450MG INJECTION if you are pregnant because CARBOPLATIN 450MG INJECTION can cause harmful effects on the unborn baby. Females should follow effective birth control methods during treatment and at least six months after the final dose of CARBOPLATIN 450MG INJECTION.

Drug-Drug Interactions Checker List

  • PEMETREXED
  • GEMCITABINE
  • PEGFILGRASTIM
  • PACLITAXEL
  • PANTOPRAZOLE
  • AMIKACIN
  • GENTAMICIN
  • KANAMYCIN
  • STREPTOMYCIN
  • TOBRAMYCIN
  • DOCETAXEL

Special Advise

  • Peripheral blood counts should be frequently monitored during carboplatin treatment and, when appropriate, until recovery is achieved.
  • CARBOPLATIN 450MG INJECTION should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking CARBOPLATIN 450MG INJECTION.
  • Your doctor may get routine blood tests done to monitor your liver function, electrolyte levels, and blood cell count in your blood.
  • Avoid unnecessary or prolonged exposure to sunlight and UV light (such as tanning booths) and wear protective clothing, sunglasses, and sunscreen. CARBOPLATIN 450MG INJECTION may make your skin sensitive to sunlight.

Disease/Condition Glossary

Ovarian cancer: Cancer that forms in tissues of the ovary (one of a pair of female reproductive glands in which the ova, or eggs, are formed).

Small-cell lung cancer is a disease in which malignant (cancer) cells form in the tissues of the lung.

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