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Carboplatin

About

Carboplatin belongs to a group of anti-cancer medicines used for the treatment of ovarian cancer and small-cell lung cancer. It may sometimes be used to treat other cancers. Cancer forms in tissues of the ovary (one of a pair of female reproductive glands in which the ova, or eggs, are formed). Small-cell lung cancer is a disease in which malignant (cancer) cells form in the tissues of the lung.

Carboplatin contains 'Carboplatin'. Carboplatin acts by penetrating the cell wall and binding to the cell's DNA, stopping the cell from naturally dividing and functioning, ultimately destroying the cell. These medicines target cancer cells because they often affect rapidly dividing cells.

Carboplatin is prescribed by a doctor experienced in the use of medications to treat cancer. It is administered by a healthcare professional as an injection. You may experience nausea, diarrhoea, vomiting, thrombocytopenia (a low platelet count), peripheral neuropathy (nerves malfunction), nephrotoxicity at high doses and electrolyte disturbances. Most of these side effects of Carboplatin do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

To treat your condition effectually, continue taking Carboplatin for as long as your doctor has prescribed. Do not stop the Carboplatin midway. Talk to your doctor before taking Carboplatin if you have severe allergic reactions to Carboplatin or other platinum-containing compounds or if you are suffering from peripheral neuropathy (nerves malfunction), hypotension, cardiac disorders, severe lung problems, pulmonary disorders, posterior reversible encephalopathy syndrome disorders, gastrointestinal disorders, thrombocytopenia (a low platelet count), neutropenia (low white blood cell count), tumour lysis syndrome (metabolic abnormalities that can occur as a complication during the treatment of cancer), hepatic disorders. Carboplatin should not be employed in patients with severe bone marrow depression or significant bleeding. Avoid taking Carboplatin if you are pregnant or breastfeeding because this Carboplatin can cause harmful effects on the unborn baby. Both women and men using this Carboplatin should use birth control to avoid pregnancy.

Uses of Carboplatin

Ovarian cancer and Small cell lung cancer

Medicinal Benefits

Carboplatin contains 'Carboplatin' which belongs to a group of anti-cancer medicines used to treat ovarian cancer and small cell lung cancer. It works by damaging the genetic material (DNA) of the cancer cells, which stops their growth and multiplication. It can be used alone or with other chemotherapy drugs depending on your cancer type.

Directions for Use

Parenteral: Carboplatin will be administered by a qualified healthcare professional. Kindly do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Carboplatin

  • Nausea
  • Vomiting
  • Diarrhoea
  • Loss of appetite
  • Hair loss and numbness
  • Tingling
  • Burning
  • Pain in the hands or feet
  • Nephrotoxicity at high doses
  • Electrolyte disturbances
  • Thrombocytopenia (low blood platelet count)
  • Peripheral neuropathy (nerves malfunction)
  • Leukopenia (low white blood cell count)

In-Depth Precautions and Warning

Drug Warnings

Carboplatin should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Carboplatin. To treat your condition effectually, continue taking Carboplatin for as long as your doctor has prescribed. Do not stop the Carboplatin midway. Talk to your doctor before taking Carboplatin if you have severe allergic reactions to Carboplatin or other platinum-containing compounds or if you are suffering from peripheral neuropathy (nerves malfunction), hypotension, cardiac disorders, severe lung problems, pulmonary disorders, posterior reversible encephalopathy syndrome disorders, gastrointestinal disorders, thrombocytopenia (a low platelet count), neutropenia (low white blood cell count), tumour lysis syndrome (metabolic abnormalities that can occur as a complication during the treatment of cancer), hepatic disorders. Carboplatin should not be employed in patients with severe bone marrow depression or significant bleeding. Avoid taking Carboplatin if you are pregnant or breastfeeding because this Carboplatin can cause harmful effects on the unborn baby. Both women and men using this Carboplatin should use birth control to avoid pregnancy. Peripheral blood counts should be frequently monitored during Carboplatin treatment and appropriate until recovery is achieved.

Drug Interactions

Drug-Drug Interactions: Carboplatin interacts with medicines used in the treatment of chemotherapy (e.g. pemetrexed, gemcitabine, pegfilgrastim, paclitaxel, docetaxel), antacid medications (e.g. pantoprazole) and antibiotic medications (e.g. amikacin, gentamicin, kanamycin, streptomycin, tobramycin).

Drug-Food Interactions: No food interaction was found.

Drug-Disease Interactions: Inform your doctor before taking Carboplatin it requires close monitoring if you are suffering from Infection (bacterial/fungal/protozoal/viral), bleeding disorders, bone marrow depression/low blood counts, fever, renal dysfunction or disorders, peripheral neuropathy (nerves malfunction).

Drug-Drug Interactions Checker List:

  • PEMETREXED
  • GEMCITABINE
  • PEGFILGRASTIM
  • PACLITAXEL
  • PANTOPRAZOLE
  • AMIKACIN
  • GENTAMICIN
  • KANAMYCIN
  • STREPTOMYCIN
  • TOBRAMYCIN
  • DOCETAXEL
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      You are recommended to avoid alcohol consumption while taking Carboplatin. It could lead to avoiding unpleasant side effects.

    • Safety Warning

      Pregnancy

      unsafe

      Carboplatin should not be used during pregnancy because it causes harm to the fetus (newborn baby). Both women of childbearing potential and men must use an effective contraception method while taking Carboplatin and at least six months afterwards. Please consult your doctor about any concerns regarding this.

    • Safety Warning

      Breast Feeding

      unsafe

      Carboplatin should not be taken during breastfeeding as it passes into the breastmilk and may harm the nursing baby. It is contraindicated in breastfeeding mothers. Please consult your doctor about any concerns regarding this.

    • Safety Warning

      Driving

      caution

      Carboplatin may affect your reactions and your ability to drive. Possible side effects of chemotherapy with Carboplatin may occur, such as nausea and vomiting. If you are affected by these side effects, you should not drive and/or operate machines that require you to be alert.

    • Safety Warning

      Liver

      caution

      If you have had a history or evidence of any liver-related diseases, please consult the doctor before taking Carboplatin. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

    • Safety Warning

      Kidney

      caution

      If you have had a history or evidence of any kidney-related diseases, please consult the doctor before taking Carboplatin. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

    • Safety Warning

      Children

      unsafe

      Efficacy and safety have not been established. Please consult your doctor. Your doctor will weigh the benefits and potential risks before prescribing them.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Eat a healthy diet and exercise regularly to maintain proper weight.
    • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs in your diet.
    • Get optimal sleep; rest well.
    • Performing yoga may also help in improving both physical and mental health.
    • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
    • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
    • Avoid smoking and alcohol consumption.
    • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

    Special Advise

    • Peripheral blood counts should be frequently monitored during carboplatin treatment and, when appropriate, until recovery is achieved.
    • Carboplatin should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Carboplatin.
    • Your doctor may get routine blood tests done to monitor your liver function, electrolyte levels, and blood cell count in your blood.
    • Avoid unnecessary or prolonged exposure to sunlight and UV light (such as tanning booths) and wear protective clothing, sunglasses, and sunscreen. Carboplatin may make your skin sensitive to sunlight.

    Patients Concern

    Disease/Condition Glossary

    Ovarian cancer: Cancer that forms in tissues of the ovary (one of a pair of female reproductive glands in which the ova, or eggs, are formed).

    Small-cell lung cancer is a disease in which malignant (cancer) cells form in the tissues of the lung.

    FAQs

    Carboplatin contains 'Carboplatin'. Carboplatin works by breaching the cellular wall and binding to the cell’s DNA, preventing the cell from dividing and functioning normally, which eventually kills the cell.

    Yes, Carboplatin can cause low neutrophils levels, a type of white blood cells that help fight infections. If your white blood cells become low, you can be at higher risk for infections. Tell your doctor if you develop a fever or believe you have an infection.

    Carboplatin should be administered under the supervision of a qualified physician experienced in the use of cancer chemotherapeutic agents.

    Before you receive treatment with Carboplatin, tell your doctor about all of your medical conditions. You should not receive Carboplatin if you are allergic to carboplatin or any contents in Carboplatin. It should not be employed in patients with severe bone marrow depression or significant bleeding.

    If not given an inappropriate dose, Carboplatin can cause toxic effects, although not everyone gets it. So, Carboplatin is prescribed by a doctor experienced in the use of medications to treat cancer only.

    Avoid taking Carboplatin if you are pregnant because Carboplatin can cause harmful effects on the unborn baby. Females should follow effective birth control methods during treatment and at least six months after the final dose of Carboplatin.

    Available Medicines for

    Carboplatin

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