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  3. Carbozest 450 Injection 45 ml

Carbozest 450 Injection 45 ml, Pack of 1 Injection
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
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Composition :

CARBOPLATIN-10MG

Manufacturer/Marketer :

Zee Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Carbozest 450 Injection

Carbozest 450 Injection belongs to a group of anti-cancer medicines used for the treatment of ovarian cancer and small-cell lung cancer. It may sometimes be used to treat other cancers. Cancer forms in tissues of the ovary (one of a pair of female reproductive glands in which the ova, or eggs, are formed). Small-cell lung cancer is a disease in which malignant (cancer) cells form in the tissues of the lung.

Carbozest 450 Injection contains 'Carboplatin'. Carboplatin acts by penetrating the cell wall and binding to the cell's DNA, stopping the cell from naturally dividing and functioning, ultimately destroying the cell. These medicines target cancer cells because they often affect rapidly dividing cells.

Carbozest 450 Injection is prescribed by a doctor experienced in the use of medications to treat cancer. It is administered by a healthcare professional as an injection. You may experience nausea, diarrhoea, vomiting, thrombocytopenia (a low platelet count), peripheral neuropathy (nerves malfunction), nephrotoxicity at high doses and electrolyte disturbances. Most of these side effects of Carbozest 450 Injection do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

To treat your condition effectually, continue taking Carbozest 450 Injection for as long as your doctor has prescribed. Do not stop the Carbozest 450 Injection midway. Talk to your doctor before taking Carbozest 450 Injection if you have severe allergic reactions to Carbozest 450 Injection or other platinum-containing compounds or if you are suffering from peripheral neuropathy (nerves malfunction), hypotension, cardiac disorders, severe lung problems, pulmonary disorders, posterior reversible encephalopathy syndrome disorders, gastrointestinal disorders, thrombocytopenia (a low platelet count), neutropenia (low white blood cell count), tumour lysis syndrome (metabolic abnormalities that can occur as a complication during the treatment of cancer), hepatic disorders. Carbozest 450 Injection should not be employed in patients with severe bone marrow depression or significant bleeding. Avoid taking Carbozest 450 Injection if you are pregnant or breastfeeding because this Carbozest 450 Injection can cause harmful effects on the unborn baby. Both women and men using this Carbozest 450 Injection should use birth control to avoid pregnancy.

Uses of Carbozest 450 Injection

Ovarian cancer and Small cell lung cancer

Directions for Use

Parenteral: Carbozest 450 Injection will be administered by a qualified healthcare professional. Kindly do not self-administer.

Medicinal Benefits

Carbozest 450 Injection contains 'Carboplatin' which belongs to a group of anti-cancer medicines used to treat ovarian cancer and small cell lung cancer. It works by damaging the genetic material (DNA) of the cancer cells, which stops their growth and multiplication. It can be used alone or with other chemotherapy drugs depending on your cancer type.

Storage

Store in a cool and dry place away from sunlight
Side effects of Carbozest 450 Injection 45 ml
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in white blood cells which may lead to impaired immunity.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Limit the intake of alcohol consumption.
  • Get vaccinated against hepatitis B and C.
  • Maintain a healthy weight through diet and exercise.
  • Eat healthy diet containing fruits, vegetables, whole grains, and lean proteins.
  • Include vitamin D in your diet.
  • Apply a hot/cold pack to the affected area.
  • Doing gentle exercises can help cope with pain by stretching muscles.
  • Get enough sleep. It helps enhance mood and lower pain sensitivity.
  • Avoid alcohol, smoking and tobacco as they can increase pain.
  • Follow a well-balanced meal.
  • Meditation and massages may also help with pain.

Drug Warnings

Carbozest 450 Injection should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Carbozest 450 Injection. To treat your condition effectually, continue taking Carbozest 450 Injection for as long as your doctor has prescribed. Do not stop the Carbozest 450 Injection midway. Talk to your doctor before taking Carbozest 450 Injection if you have severe allergic reactions to Carbozest 450 Injection or other platinum-containing compounds or if you are suffering from peripheral neuropathy (nerves malfunction), hypotension, cardiac disorders, severe lung problems, pulmonary disorders, posterior reversible encephalopathy syndrome disorders, gastrointestinal disorders, thrombocytopenia (a low platelet count), neutropenia (low white blood cell count), tumour lysis syndrome (metabolic abnormalities that can occur as a complication during the treatment of cancer), hepatic disorders. Carbozest 450 Injection should not be employed in patients with severe bone marrow depression or significant bleeding. Avoid taking Carbozest 450 Injection if you are pregnant or breastfeeding because this Carbozest 450 Injection can cause harmful effects on the unborn baby. Both women and men using this Carbozest 450 Injection should use birth control to avoid pregnancy. Peripheral blood counts should be frequently monitored during Carbozest 450 Injection treatment and appropriate until recovery is achieved.

Drug-Drug Interactions

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CarboplatinSorafenib
Critical
CarboplatinCladribine
Severe

Drug-Drug Interactions

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CarboplatinSorafenib
Critical
How does the drug interact with Carbozest 450 Injection 45 ml:
Co-administration of Sorafenib with Carbozest 450 Injection 45 ml can increase the risk or severity of serious side effects.

How to manage the interaction:
Taking Sorafenib with Carbozest 450 Injection 45 ml together is not recommended as it can cause an interaction, consult a doctor before taking it. However if you experience any unusual symptoms, consult the doctor. Do not stop using any medications without consulting a doctor.
CarboplatinCladribine
Severe
How does the drug interact with Carbozest 450 Injection 45 ml:
Using cladribine and Carbozest 450 Injection 45 ml together can increase the risk of serious infections.

How to manage the interaction:
Co-administration of Carbozest 450 Injection 45 ml and cladribine can possibly result in an interaction, but it can be taken if your doctor has advised it. However, If you experience fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, red or inflamed skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
CarboplatinBacitracin
Severe
How does the drug interact with Carbozest 450 Injection 45 ml:
Taking Carbozest 450 Injection 45 ml and bacitracin can increase the risk of nephrotoxicity(kidney damage).

How to manage the interaction:
Co-administration of Carbozest 450 Injection 45 ml and bacitracin can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms consult the doctor. Do not discontinue any medications without a doctor's advice.
CarboplatinThiotepa
Severe
How does the drug interact with Carbozest 450 Injection 45 ml:
Using Carbozest 450 Injection 45 ml with Thiotepa can increase the risk and severity of side effects.

How to manage the interaction:
There may be a possibility of interaction between Thiotepa and Carbozest 450 Injection 45 ml, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, consult the doctor. Do not stop using any medications without talking to a doctor.
CarboplatinFingolimod
Severe
How does the drug interact with Carbozest 450 Injection 45 ml:
Using Carbozest 450 Injection 45 ml with Fingolimod can increase the risk of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between Carbozest 450 Injection 45 ml and Fingolimod, you can take these medicines together if prescribed by your doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
CarboplatinThalidomide
Severe
How does the drug interact with Carbozest 450 Injection 45 ml:
Taking Carbozest 450 Injection 45 ml with thalidomide can increase the risk of blood clots.

How to manage the interaction:
Co-administration of Carbozest 450 Injection 45 ml with thalidomide can possibly result in an interaction, but it can be taken if your doctor has advised it. However, If you experience chest pain, breathing difficulty, coughing up blood, and pain, redness, or swelling in an arm or leg, sudden loss of vision, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
CarboplatinEtanercept
Severe
How does the drug interact with Carbozest 450 Injection 45 ml:
Taking Carbozest 450 Injection 45 ml with etanercept may increase the risk of serious infections.

How to manage the interaction:
Co-administration of Carbozest 450 Injection 45 ml and etanercept can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm (mucous secretion), red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
CarboplatinLeflunomide
Severe
How does the drug interact with Carbozest 450 Injection 45 ml:
Co-administration of leflunomide with Carbozest 450 Injection 45 ml can increase the risk of infections.

How to manage the interaction:
Co-administration of Carbozest 450 Injection 45 ml with leflunomide can possibly result in an interaction, but it can be taken if your doctor has advised it. However, If you experience fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm(mucous secretion), red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without consulting your doctor.
CarboplatinTopotecan
Severe
How does the drug interact with Carbozest 450 Injection 45 ml:
When Carbozest 450 Injection 45 ml is used with topotecan, it may increase the risk of side effects.

How to manage the interaction:
Co-administration of Carbozest 450 Injection 45 ml with clozapine can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue any medications without consulting your doctor.
CarboplatinCertolizumab
Severe
How does the drug interact with Carbozest 450 Injection 45 ml:
Using Carbozest 450 Injection 45 ml with Certolizumab can increase the risk of developing serious infections.

How to manage the interaction:
Taking Carbozest 450 Injection 45 ml with Certolizumab together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs in your diet.
  • Get optimal sleep; rest well.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Carbozest 450 Injection Substitute

Substitutes safety advice

Product Substitutes

Drug-Diseases Interactions

verifiedApollotooltip
CARBOPLATIN-10MGOther and unspecified infectious diseases
Moderate
CARBOPLATIN-10MGOther disorders of kidney and ureter, not elsewhere classified
Moderate

Drug-Diseases Interactions

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CARBOPLATIN-10MGOther and unspecified infectious diseases
Moderate
How does the disease interact with Carbozest 450 Injection 45 ml:
Antineoplastic drugs regularly can, to variable degrees, promote myelosuppression due to their cytotoxic effects on rapidly growing tissues.

How to manage the interaction:
If you experience any signs or symptoms suggesting infection such as fever, sore throat, or local infection during antineoplastic therapy, immediately consult your doctor. Close clinical monitoring of hematopoietic function is recommended.
CARBOPLATIN-10MGOther disorders of kidney and ureter, not elsewhere classified
Moderate
How does the disease interact with Carbozest 450 Injection 45 ml:
The kidney is the main organ used to remove Carbozest 450 Injection 45 ml. Patients with a creatinine clearance of less than 60 mL/min had lower total body and renal clearance of Carbozest 450 Injection 45 ml.

How to manage the interaction:
If you have any kidney related problems, do not forget to mention it to your doctor, a close monitoring is required.
CARBOPLATIN-10MGHaemorrhage, not elsewhere classified
Mild
How does the disease interact with Carbozest 450 Injection 45 ml:
Patients who have substantial bleeding should not use Carbozest 450 Injection 45 ml. Both severe myelosuppression and dose-dependent thrombocytopenia are brought on by Carbozest 450 Injection 45 ml.

How to manage the interaction:
The use of Carbozest 450 Injection 45 ml is not advisable if you have significant bleeding. If you experience any signs or symptoms suggesting bleeding such as petechiae, purpura, epistaxis, hemoptysis, hematuria, and melena, consult your doctor. Close clinical monitoring of hematopoietic function is recommended.

FAQs

Drug-Drug Interactions Checker List

  • PEMETREXED
  • GEMCITABINE
  • PEGFILGRASTIM
  • PACLITAXEL
  • PANTOPRAZOLE
  • AMIKACIN
  • GENTAMICIN
  • KANAMYCIN
  • STREPTOMYCIN
  • TOBRAMYCIN
  • DOCETAXEL

Special Advise

  • Peripheral blood counts should be frequently monitored during carboplatin treatment and, when appropriate, until recovery is achieved.
  • Carbozest 450 Injection should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Carbozest 450 Injection.
  • Your doctor may get routine blood tests done to monitor your liver function, electrolyte levels, and blood cell count in your blood.
  • Avoid unnecessary or prolonged exposure to sunlight and UV light (such as tanning booths) and wear protective clothing, sunglasses, and sunscreen. Carbozest 450 Injection may make your skin sensitive to sunlight.

Disease/Condition Glossary

Ovarian cancer: Cancer that forms in tissues of the ovary (one of a pair of female reproductive glands in which the ova, or eggs, are formed).

Small-cell lung cancer is a disease in which malignant (cancer) cells form in the tissues of the lung.

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