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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Composition :

CARMUSTINE-100MG

Manufacturer/Marketer :

GLS Pharma Ltd

Consume Type :

Parenteral

Expires on or after :

Return Policy :

Not Returnable

About Carnumax 100 Injection

Carnumax 100 Injection is a chemotherapeutic medicine used in the treatment of brain tumors. A tumor is defined as the formation of solid mass tissue due to the abnormal growth of cells. A brain tumor is a serious condition where the cells (cancerous or non-cancerous) grow abnormally in the brain. Carnumax 100 Injection is also used in the treatment of multiple myeloma in combination with prednisone, Hodgkin’s Disease, and non-Hodgkin’s Disease in combination with other approved drugs.

Carnumax 100 Injection contains Carmustine, which belongs to the alkylating agents class. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis. This causes shrinkage of tumor cells and thereby prevents the growth and further spread of cancerous or non-cancerous cells.

Carnumax 100 Injection may cause certain side effects, such as nausea, vomiting, headache, pale skin, dizziness, stomach upset, tiredness, loss of balance, and pain at the site of injection. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Carnumax 100 Injection is a parenteral preparation. A trained healthcare professional will administer it. Hence, do not self-administer.

Carnumax 100 Injection should be avoided if you are allergic to it or any other components present in it. Let your doctor know about your complete medical history, including current medication, to rule out any side effects/interactions. Before administration, inform your doctor if you have liver/kidney disease, cardiac disorders, or respiratory conditions. Carnumax 100 Injection may cause pulmonary toxicity, bone marrow suppression, gastrointestinal toxicity, nephrotoxicity and hepatotoxicity in some patients. Hence, careful monitoring should be done during the entire treatment. This medicine is known to cause fetal harm in pregnant women. Hence, inform your doctor if you are pregnant or are planning to become pregnant. Breastfeeding should be discontinued in nursing mothers during the treatment.

Uses of Carnumax 100 Injection

Brain Tumors, Multiple Myeloma, Hodgkin’s Disease, Non-Hodgkin’s Disease.

Directions for Use

Carnumax 100 Injection will be administered by a trained healthcare professional. Hence, do not self-administer. 

Key Benefits

Carnumax 100 Injection contains Carmustine, which belongs to the alkylating agents class. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis. This causes shrinkage of tumor cells and thereby prevents the growth and further spread of cancerous or non-cancerous cells.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Carnumax 100 Injection should be avoided if you are allergic to it or any other components present in it. Let your doctor know about your complete medical history, including current medication, to rule out any side effects/interactions. Before administration, inform your doctor if you have liver/kidney disease, cardiac disorders, or respiratory conditions. Carnumax 100 Injection may cause pulmonary toxicity, bone marrow suppression, gastrointestinal toxicity, nephrotoxicity and hepatotoxicity in some patients. Hence careful monitoring should be done during the entire treatment. This medicine is known to cause fetal harm in pregnant women. Hence, inform your doctor if you are pregnant or are planning to become pregnant. Breastfeeding should be discontinued in nursing mothers during the treatment. It is unknown whether Carnumax 100 Injection can be administered in children or not. If administered, close monitoring of the child is needed. Avoid alcohol consumption and smoking as it can lead to serious adverse effects.

Diet & Lifestyle Advise

  • After your treatment begins, several dietary adjustments can help you control side effects.
  • Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
  • Plant-based proteins are among the greatest meals to take during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans, and legumes.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast and fried food, processed meats, refined carbs and added sugars.

Side Effects of Carnumax 100 Injection

  • Nausea
  • Dizziness
  • Stomach upset
  • Headache
  • Vomiting
  • Pale skin
  • Tiredness
  • Loss of balance
  • Diarrhoea
  • Cough
  • Decreased platelet count
  • Bruising or bleeding gums
  • Pain at the site of injection

Habit Forming

No

Therapeutic Class

[CHEMOTHERAPY]

All Substitutes & Brand Comparisons

FAQs

Drug-Drug Interactions Checker List

  • ABACAVIR
  • ZIDOVUDINE
  • ADEFOVIR
  • ABATACEPT
  • ETANERCEPT
  • ACENOCOUMAROL
  • WARFARIN
  • PHENYTOIN

Special Advise

  • Carnumax 100 Injection should be administered only by a trained and experienced oncologist.
  • A blood test should be performed such as LFT, RFT, and PFT, to check for liver/kidney function, and pulmonary function.
  • Weekly blood tests should be done for at least six weeks after the dose is administered to check for CBC (Complete blood count).
  • Carnumax 100 Injection should be administered carefully without touching the skin as it can cause serious hyperpigmentation. Hence where gloves during administration.

Disease/Condition Glossary

Brain Tumors: It is a serious condition where the cells (cancerous or non-cancerous) grow abnormally in the brain. A tumor is defined as the formation of solid mass tissue due to the abnormal growth of cells. There are different types of brain tumors which can be either benign (non-cancerous) or malignant (cancerous). Carnumax 100 Injection is used in the treatment of glioblastoma (a malignant tumor that occurs in the brain and spinal cord), brainstem glioma (a tumor that affects the brain stem of the CNS), medulloblastoma (a cancerous tumor that mostly occurs in children affecting the cerebellum (lower back part of the brain)), astrocytoma (growth of cells in astrocytes which support and connect nerve cells), ependymoma (a tumor that occurs outside the CNS or within the brain parenchyma, and metastatic brain tumors.

Hodgkin’s Disease: Hodgkin’s disease or lymphoma is a blood cancer of a certain type of cells called WBCs, specifically lymphocytes. Lymphocytes normally help control infection and maintain the body's normal immunity. However, in a cancerous state, there is an abnormal multiplication of these blood cells, causing many problems such as fatigue, fever, loss of appetite, itching, night sweats and lymph node swelling.

Multiple myeloma: It is a type of cancerous tumor that affects the plasma cells of the bone marrow. These cells collect in the bone marrow and divide uncontrollably, leading to kidney and bone damage. Symptoms include bone pain, loss of appetite, fever, and frequent infections. Generally, multiple myeloma cannot be cured, but the signs and symptoms can be reduced greatly or disappear after a period of time.

Have a query?

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Alcohol

Safe if prescribed

Avoid alcohol consumption while on treatment with Carnumax 100 Injection to prevent serious adverse effects.

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Pregnancy

Consult your doctor

Carnumax 100 Injection is not recommended for use in pregnancy as it may harm your fetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Carnumax 100 Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Limited data is available on the effect of Carnumax 100 Injection on breastfeeding. Hence, if you are a nursing mother, inform your doctor before receiving Carnumax 100 Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Safe if prescribed

Carnumax 100 Injection will be administered in the hospital setting. Hence, avoid driving.

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Liver

Consult your doctor

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Carnumax 100 Injection. A dose adjustment of this medicine or a suitable alternative may be advised based on your condition.

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Kidney

Consult your doctor

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving Carnumax 100 Injection. A dose adjustment of this medicine or a suitable alternative may be advised based on your condition.

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Children

Safe if prescribed

Limited information is available for the use of Carnumax 100 Injection in children. Hence, it will be given to the children only if needed. If administered, careful monitoring of the child is needed.

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