Celoclib 125 mg Capsule 21's

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Reviewed By Hari Kumar , MBBS

MRP ₹13500

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Whats That

About Celoclib 125 mg Capsule

Celoclib 125 mg Capsule belongs to the group of anti-cancer drugs used to treat certain types of breast cancer. Cancer is the uninhibited and uncontrolled growth of cells in the body. Breast cancer is cancer that forms in the cells of the breast. It can form in the lobules, ducts or tubules of the breast or in the breast tissue itself.

Celoclib 125 mg Capsule contains Palbociclib that works by blocking proteins necessary for cell growth, thereby causing cell death and arresting the uncontrolled production of new cells. Thus, Celoclib 125 mg Capsule is effective in controlling cancer cells from multiplying and is used in the treatment of breast cancer.

Take Celoclib 125 mg Capsule as prescribed. In some cases, Celoclib 125 mg Capsule may cause certain common side effects such as weakness, loss of appetite, infections and dry skin. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist or worsen.

It is advisable to inform the doctor if you are allergic to any of its components. Do not take Celoclib 125 mg Capsule if you are pregnant or breastfeeding. Celoclib 125 mg Capsule may cause tiredness, so drive only if you are alert. Celoclib 125 mg Capsule is not recommended for use in children below 18years. Keep your doctor informed about your health condition and medications to rule out any interactions.

Uses of Celoclib 125 mg Capsule

Breast Cancer

Directions for Use

Take Celoclib 125 mg Capsule preferably with a meal. Swallow it as a whole with water. Do not crush, chew or break it.

Medicinal Benefits

Celoclib 125 mg Capsule is an anti-cancer drug used in the treatment of a particular type of breast cancer that is hormone receptor-positive and human epidermal growth factor receptor-2-negative. Celoclib 125 mg Capsule works by blocking the production of proteins called cyclin-dependent kinase 4 and 6 that are responsible for cell growth and division. By blocking them, Celoclib 125 mg Capsule nips cell growth in the bud and prevents cancer cells from spreading further. Thus, Celoclib 125 mg Capsule helps treat breast cancer.

Side effects of Celoclib 125 mg Capsule

Fatigue

Rest well; get enough sleep.
Eat a balanced diet and drink enough water.
Manage stress with yoga and meditation.
Limit alcohol and caffeine.
Physical activities like walking or jogging might help boost energy and make you feel less tired.

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Hair Loss

Eat protein-rich foods like fish, poultry, eggs, and legumes.
Include foods with minerals and vitamins essential for hair health.
Join a support group to connect with others experiencing hair loss.
Openly discuss your feelings about hair loss.
Consider covering up with wigs, hats, or scarves.
Be patient and avoid seeking miracle cures.

Loose And Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Anemia

Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
Consume vitamin C-rich foods as they aid iron absorption.
Limit tea, cocoa, and coffee as these can slow iron absorption.
Exercise regularly; however, do not overdo it.

Rash

Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
Protect your skin from extreme heat and try to apply wet compresses.
Soak in the cool bath, which gives a soothing impact to the affected area.

Weakness

Rest well; get enough sleep.
Eat a balanced diet and drink enough water.
Manage stress with yoga and meditation.
Limit alcohol and caffeine.
Physical activities like walking or jogging might help boost energy and make you feel less tired.

Drug Warnings

Do not take St. John's wort or grapefruit/grapefruit juice with Celoclib 125 mg Capsule . It is advisable to inform the doctor if you are allergic to any of its components. Do not take Celoclib 125 mg Capsule if you are pregnant or breastfeeding. Celoclib 125 mg Capsule may cause tiredness, so drive only if you are alert. Celoclib 125 mg Capsule is not recommended for use in children below 18years. If you experience any signs or symptoms of infections, inform your doctor. Keep your doctor informed about your health condition and medications to rule out any interactions. Consult your doctor immediately if you experience symptoms such as dry cough, chest pain, difficulty breathing or shortness of breath as it could be an indication of lung inflammation

Drug-Drug Interactions

PalbociclibKetoconazole

Severe

PalbociclibMorphine

Severe

Drug-Drug Interactions

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PalbociclibKetoconazole

Severe

How does the drug interact with Celoclib 125 mg Capsule:
Coadministration of Ketoconazole and Celoclib 125 mg Capsule may increase the blood level of Celoclib 125 mg Capsule.

How to manage the interaction:
Although taking Ketoconazole and Celoclib 125 mg Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience nausea, vomiting, diarrhea, loss of appetite, mouth sores, hair loss, weakness, pain, numbness, or tingling in the hands and feet, more severely, consult a doctor. Without consulting a doctor, never stop taking any drugs.

PalbociclibMorphine

Severe

How does the drug interact with Celoclib 125 mg Capsule:
Co-administration of Celoclib 125 mg Capsule with Morphine may increase the blood levels and side effects of morphine.

How to manage the interaction:
Taking Morphine with Celoclib 125 mg Capsule can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.

PalbociclibCladribine

Severe

How does the drug interact with Celoclib 125 mg Capsule:
Taking Cladribine with Celoclib 125 mg Capsule can increase the risk of developing serious infections.

How to manage the interaction:
Taking Cladribine with Celoclib 125 mg Capsule together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.

PalbociclibPosaconazole

Severe

How does the drug interact with Celoclib 125 mg Capsule:
When Celoclib 125 mg Capsule is taken with Posaconazole can increase the blood levels of Celoclib 125 mg Capsule.

How to manage the interaction:
Although there is an interaction between posaconazole and Celoclib 125 mg Capsule, it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, diarrhea, less desire to eat, mouth sores, hair loss, weakness, pain, numbness, or tingling in the hands and feet contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Meditation and yoga have been proven very effective in helping cancer patients maintain a healthy attitude and body.
Eat more lean meats, healthy fats, fruits, vegetables and whole-grain foods to give you more energy.
Stay hydrated by drinking plenty of water as dehydration is often seen in cancers.
Taking a stroll in the garden, or spending 30 minutes of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired.
Avoid smoking and alcohol consumption.

Side Effects of Celoclib 125 mg Capsule

Loss of appetite
Dry skin
Weakness
Infection
Hair loss
Fever
Inflammation of the mouth and lips

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Celoclib 125 mg Capsule work?

Celoclib 125 mg Capsule works blocking proteins responsible for cell growth and division, thereby arresting the progression of cancer cells.

Can I stop taking Celoclib 125 mg Capsule on my own?

Do not stop taking Celoclib 125 mg Capsule on your own. You are advised to take Celoclib 125 mg Capsule for as long as your doctor has prescribed it for you depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Celoclib 125 mg Capsule .

I have fibroadenoma. Can Celoclib 125 mg Capsule help?

A fibroadenoma is a benign state. Celoclib 125 mg Capsule is indicated only in case of cancers. Please consult your doctor in case of any concerns.

Can Celoclib 125 mg Capsule affect my ability to get pregnant?

Celoclib 125 mg Capsule can reduce fertility in men. Therefore, consider sperm preservation before starting Celoclib 125 mg Capsule if you wish to father a child in the future. Effects on female fertility have not been established. Please consult your doctor before using Celoclib 125 mg Capsule .

Does Celoclib 125 mg Capsule increase the risk of infections?

Celoclib 125 mg Capsule may reduce white blood cell count, thereby weakening the immune system. This might increase your risk of infections. If you notice any signs or symptoms of infections, consult your doctor.

Drug-Drug Interactions Checker List

RITONAVIR
NELFINAVIR
SAQUINAVIR
LOPINAVIR
TELAPREVIR
ITRACONAZOLE
KETOCONAZOLE
VORICONAZOLE
POSACONAZOLE
CLARITHROMYCIN
TELITHROMYCIN
ABATACEPT
QUINIDINE
COLCHICINE
ALFENTANIL
FENTANYL
TACROLIMUS
CYCLOSPORINE
PIMOZIDE
ERGOTAMINE

Special Advise

Discuss contraception with your doctor while taking Celoclib 125 mg Capsule .
People on treatment with Celoclib 125 mg Capsule should use additional contraception (barrier method such as condoms). Contraception should be continued 3 weeks post-treatment for women and 14 weeks post-treatment for men.
You may want to consider sperm storage before starting Celoclib 125 mg Capsule . Seek counsel on the same from a qualified healthcare individual and/or sperm bank.
Regular complete blood count monitoring is advised.

Disease/Condition Glossary

Breast Cancer: Breast cancer is a type of cancer that develops in breast cells. Breast cancer may form in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), in the fatty tissue or the fibrous connective tissue within the breast. The tumour cells invade other healthy breast cells and can travel to lymph nodes which are a primary pathway for the cancer cells to move to other parts of the body. Symptoms of breast cancer include a lump in the breast or tissue thickening which feels different than the normal surrounding tissues, breast pain, redness, swelling, nipple discharge other than breast milk, bloody discharge, unexplained change in shape, size or appearance of the breast, peeling, flaking or scaling of the skin, and a lump or swelling under the arm.