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Reviewed By Sureshvarma D , MPharma

About Celofos 1000 Injection 1 ml

Celofos 1000 Injection 1 ml belongs to a group of medications called ‘anti-neoplastic'. It is used in the treatment of blood cancer, breast cancer, non-small cell lung cancer, ovarian cancer (a type of cancer that begins in the ovaries), testicular cancer (cancer occurs in the testicles (testes), (which are located inside the scrotum, a loose bag of skin underneath the penis), and pancreatic cancer (a type of cancer that begins in the pancreas). Blood cancer begins in blood-forming tissue, such as the bone marrow or the immune system's cells. Examples of blood cancer are leukemia ( a blood cancer caused by a rise in the number of white blood cells in your body), lymphoma (cancer that begins in infection-fighting cells of the immune system, called lymphocytes), and multiple myeloma (cancer that forms in a type of white blood cell called a plasma cell).

Celofos 1000 Injection 1 ml contains ‘ifosfamide’, which is an anti-cancer drug. Celofos 1000 Injection 1 ml works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication. 

Celofos 1000 Injection 1 ml will be administered by a healthcare professional; do not self-administer. In some cases, you may experience certain common side effects such as nausea, vomiting, anemia (low number of red blood cells), hair loss, decreased white blood cell count, infection, blood in urine, CNS toxicity. Most of these side effects of Celofos 1000 Injection 1 ml do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

Do not take Celofos 1000 Injection 1 ml if you are allergic to any other ingredients present in it. Do not self-administer Celofos 1000 Injection 1 ml. Before taking Celofos 1000 Injection 1 ml, talk to your doctor if you have a history of kidney disease, heart diseases, liver diseases, bone marrow suppression, cystitis, CNS toxicity. Celofos 1000 Injection 1 ml is not recommended during pregnancy as it may affect the unborn baby. Tell your doctor if you are breastfeeding before taking Celofos 1000 Injection 1 ml. It is not recommended for use in children under 1 year of age. 

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Whats That

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Non returnable*
COD available

Online payment accepted

Composition

IFOSFAMIDE-1GM

Consume Type

PARENTERAL

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of Celofos 1000 Injection 1 ml

Blood cancer, breast cancer, non-small cell lung cancer, ovarian cancer, testicular cancer, and pancreatic cancer.

Medicinal Benefits

Celofos 1000 Injection 1 ml contains ‘ifosfamide’, which is an anti-cancer drug. It is used to treat blood cancer, breast cancer, non-small cell lung cancer, ovarian cancer, testicular cancer, and pancreatic cancer. Celofos 1000 Injection 1 ml works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication. 

Side Effects of Celofos 1000 Injection 1 ml

  • Nausea
  • Vomiting
  • Anemia (low number of red blood cells)
  • Hair loss
  • Decreased white blood cell count
  • Infection
  • Blood in urine
  • CNS toxicity
  • Dehydration
  • Dry mouth/increased thirst
  • Pale/wrinkled skin
  • Temporary hair loss
  • Trouble breathing

Directions for Use

Celofos 1000 Injection 1 ml will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Celofos 1000 Injection 1 ml if you are allergic to any other ingredients present in it. Do not self-administer Celofos 1000 Injection 1 ml. Before taking Celofos 1000 Injection 1 ml, talk to your doctor if you have a history of kidney disease, heart diseases, liver diseases,  cystitis, CNS toxicity. Celofos 1000 Injection 1 ml is not recommended during pregnancy as it may affect the unborn baby. Tell your doctor if you are breastfeeding before taking Celofos 1000 Injection 1 ml. It is not recommended for use in children under 1 year of age. Celofos 1000 Injection 1 ml should be used with caution in infections. Because the chances of infections are more in patients receiving this medicine. Hold the chemotherapy and start with broad-spectrum antibiotics if there are any signs and symptoms of fever. Close monitoring of the body temperature and the blood cell count is necessary. Consumption of alcohol is not recommended while receiving this Celofos 1000 Injection 1 ml as it may increase the risk of adverse effects such as dizziness, drowsiness, abnormal muscle movements, seizures. Celofos 1000 Injection 1 ml may cause bone marrow suppression, which lowers the white blood cell count (neutrophils) and platelets. Close monitoring of blood cell count is necessary.

Therapeutic Class

ANTINEOPLASTIC

Drug-Drug Interactions

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IfosfamideCidofovir
Critical
IfosfamideEtanercept
Severe

Drug-Drug Interactions

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IfosfamideCidofovir
Critical
How does the drug interact with Celofos 1000 Injection 1 ml:
Taking cidofovir with Celofos 1000 Injection 1 ml can increase the risk of kidney problems.

How to manage the interaction:
Taking Celofos 1000 Injection 1 ml with Cidofovir together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
IfosfamideEtanercept
Severe
How does the drug interact with Celofos 1000 Injection 1 ml:
When Etanercept is used with Celofos 1000 Injection 1 ml, the likelihood or severity of infection may increase.

How to manage the interaction:
Although taking Etanercept and Celofos 1000 Injection 1 ml together can cause an interaction, it can be taken if a doctor has suggested it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
IfosfamideCladribine
Severe
How does the drug interact with Celofos 1000 Injection 1 ml:
Combining Cladribine with Celofos 1000 Injection 1 ml can increase the risk of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between Celofos 1000 Injection 1 ml and Cladribine, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
IfosfamideTenofovir alafenamide
Severe
How does the drug interact with Celofos 1000 Injection 1 ml:
The combined use of Celofos 1000 Injection 1 ml and Tenofovir alafenamide can increase the risk of kidney problems.

How to manage the interaction:
Taking Celofos 1000 Injection 1 ml and Tenofovir alafenamide together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
IfosfamideLidocaine
Severe
How does the drug interact with Celofos 1000 Injection 1 ml:
Coadministration of Celofos 1000 Injection 1 ml with Lidocaine can increase the risk of methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
There may be a possibility of interaction between Celofos 1000 Injection 1 ml and Lidocaine, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
IfosfamideInfliximab
Severe
How does the drug interact with Celofos 1000 Injection 1 ml:
Combining Infliximab with Celofos 1000 Injection 1 ml can speed up the breakdown of Celofos 1000 Injection 1 ml in the body. This can increase the risk or severity of developing serious infections.

How to manage the interaction:
Co-administration of Celofos 1000 Injection 1 ml with Infliximab can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you urinate, contact a doctor right away. Don't hesitate to reach out to your doctor if you experience any of these. Do not stop using any medications without a doctor's advice.
IfosfamideThalidomide
Severe
How does the drug interact with Celofos 1000 Injection 1 ml:
Taking thalidomide together with Celofos 1000 Injection 1 ml may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Celofos 1000 Injection 1 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
IfosfamideBaricitinib
Severe
How does the drug interact with Celofos 1000 Injection 1 ml:
Coadministration of baricitinib and Celofos 1000 Injection 1 ml can raise the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Celofos 1000 Injection 1 ml if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.
IfosfamideTofacitinib
Severe
How does the drug interact with Celofos 1000 Injection 1 ml:
Taking Celofos 1000 Injection 1 ml with Tofacitinib may increase the risk of serious infection.

How to manage the interaction:
Taking Tofacitinib with Celofos 1000 Injection 1 ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. It is important to keep a close eye on your condition. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
IfosfamideClozapine
Severe
How does the drug interact with Celofos 1000 Injection 1 ml:
Co-administration of Celofos 1000 Injection 1 ml with Clozapine can increase the risk of neutropenia (low levels of neutrophils in blood).

How to manage the interaction:
Taking Celofos 1000 Injection 1 ml with Clozapine together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any signs of infection like fever, chills, or a sore throat, or experience discomfort while urinating, it's best to contact a doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • CISPLATIN
  • AMPHOTERICIN B
  • RIFAMPIN
  • DILITAZEM
  • ENALAPRIL
  • CLOZAPINE
  • CARBAMAZEPINE
  • PHENYTOIN
  • PHENOBARBITAL
  • FLUCONAZOLE
  • ITRACONAZOLE
  • KETOCONAZOLE
  • ETANERCEPT
  • ADALIMUMAB

Diet & Lifestyle Advise

  • Eat a variety of protein-rich foods that are low in fat. Include seafood, lean meat and poultry, greek yoghurts, eggs, beans, soy products, and unsalted nuts and seeds.
  • Take vitamin A foods, found in green- or orange-coloured fruits and vegetables, such as sweet potatoes, carrots, kale, spinach, and apricots.
  • Stay away from strong-smelling foods to avoid aggravating any disorders of taste.
  • Avoid fatty fried, spicy, and overly sweet foods, as they may induce nausea.
  • Avoid refined sugars (including raw, brown, and palm sugar) and refined carbohydrates, as most tumours prefer glucose as an energy source.
  • Avoid drinking alcohol.
  • Quit smoking.

Habit Forming

No

Special Advise

  • Regular monitoring of kidney, liver function, and levels of blood cells in your blood.
  • Drink plenty of fluids while taking this Celofos 1000 Injection 1 ml to minimize damage to your bladder and kidneys.

Disease/Condition Glossary

Blood cancer:  Blood cancer begins in blood-forming tissue, such as the bone marrow or the immune system's cells. Examples of blood cancer are leukemia ( a blood cancer caused by a rise in the number of white blood cells in your body), lymphoma (cancer that begins in infection-fighting cells of the immune system, called lymphocytes), and multiple myeloma (cancer that forms in a type of white blood cell called a plasma cell). Symptoms include fever, chills., fatigue, weakness, bone and joint pain, weight loss.

Ovarian cancer:  Ovarian cancer is when abnormal cells in the ovary begin to multiply out of control and form a tumor. If left untreated, the tumor can spread to other parts of the body. This is called metastatic ovarian cancer. Symptoms include abdominal bloating, pressure, pain, abnormal fullness after eating, difficulty eating, increased urination, and an increased urge to urinate.

Breast cancer: Cancer that forms in the cells of the breasts. Breast cancer can occur in women and rarely in men. Symptoms of breast cancer include a lump in the breast, bloody discharge from the nipple, and changes in the shape or texture of the nipple or breast.

Testicular cancer: Testicular cancer occurs in the testicles (testes), located inside the scrotum, a loose bag of skin underneath the penis. Symptoms include a painless lump or swelling on either testicle, pain, discomfort, numbness in a testicle or the scrotum, change in the way a testicle feels, or a feeling of heaviness the scrotum, a dull ache in the lower abdomen or groin. Sudden buildup of fluid in the scrotum.

Pancreatic cancer: Pancreatic cancer is cancer that forms in the cells of the pancreas. Pancreatic cancer begins in your pancreas tissues — an organ in your abdomen that lies behind the lower part of your stomach. Your pancreas releases enzymes that aid digestion and produce hormones that help manage your blood sugar. Symptoms include abdominal pain that radiates to your back, loss of appetite or unintended weight loss, yellowing of your skin and the whites of your eyes (jaundice), light-colored stools, dark-colored urine, itchy skin.

Non-small cell lung cancer: Non-small cell lung cancer is a disease in which malignant (cancer) cells form in the lung tissues. There are several types of non-small cell lung cancer. Smoking is the major risk factor for non-small cell lung cancer. Symptoms include a cough that won't go away, shortness of breath, weight loss, or coughing up blood.

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