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  3. Ifos 1gm Injection

Ifos 1gm Injection, Pack of 1 Injection
Ifos 1gm Injection, Pack of 1 Injection
Written By ,
Reviewed By Sureshvarma D , MPharma
Non returnable*
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Whats That

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Composition :

IFOSFAMIDE-1GM

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Ifos 1gm Injection

Ifos 1gm Injection belongs to a group of medications called ‘anti-neoplastic'. It is used in the treatment of blood cancer, breast cancer, non-small cell lung cancer, ovarian cancer (a type of cancer that begins in the ovaries), testicular cancer (cancer occurs in the testicles (testes), (which are located inside the scrotum, a loose bag of skin underneath the penis), and pancreatic cancer (a type of cancer that begins in the pancreas). Blood cancer begins in blood-forming tissue, such as the bone marrow or the immune system's cells. Examples of blood cancer are leukemia ( a blood cancer caused by a rise in the number of white blood cells in your body), lymphoma (cancer that begins in infection-fighting cells of the immune system, called lymphocytes), and multiple myeloma (cancer that forms in a type of white blood cell called a plasma cell).

Ifos 1gm Injection contains ‘ifosfamide’, which is an anti-cancer drug. Ifos 1gm Injection works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication. 

Ifos 1gm Injection will be administered by a healthcare professional; do not self-administer. In some cases, you may experience certain common side effects such as nausea, vomiting, anemia (low number of red blood cells), hair loss, decreased white blood cell count, infection, blood in urine, CNS toxicity. Most of these side effects of Ifos 1gm Injection do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

Do not take Ifos 1gm Injection if you are allergic to any other ingredients present in it. Do not self-administer Ifos 1gm Injection. Before taking Ifos 1gm Injection, talk to your doctor if you have a history of kidney disease, heart diseases, liver diseases, bone marrow suppression, cystitis, CNS toxicity. Ifos 1gm Injection is not recommended during pregnancy as it may affect the unborn baby. Tell your doctor if you are breastfeeding before taking Ifos 1gm Injection. It is not recommended for use in children under 1 year of age. 

Uses of Ifos 1gm Injection

Blood cancer, breast cancer, non-small cell lung cancer, ovarian cancer, testicular cancer, and pancreatic cancer.

Directions for Use

Ifos 1gm Injection will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Ifos 1gm Injection contains ‘ifosfamide’, which is an anti-cancer drug. It is used to treat blood cancer, breast cancer, non-small cell lung cancer, ovarian cancer, testicular cancer, and pancreatic cancer. Ifos 1gm Injection works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication. 

Storage

Store in a cool and dry place away from sunlight
Side effects of Ifos 1gm Injection
  • Eat protein-rich foods like fish, poultry, eggs, and legumes.
  • Include foods with minerals and vitamins essential for hair health.
  • Join a support group to connect with others experiencing hair loss.
  • Openly discuss your feelings about hair loss.
  • Consider covering up with wigs, hats, or scarves.
  • Be patient and avoid seeking miracle cures.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Staying hydrated helps prevent hematuria by increasing urine production. You should drink about eight glasses of fluid per day, and more in hot weather.
  • Avoiding smoking as it is linked to urinary tract cancers.
  • Eat berries like Cranberries, blueberries, and raspberries can help promote urinary tract health and protect against infection.
  • Taking Vitamin C can help treat urinary tract infections.
  • Avoid irritants that can contribute to hematuria.
  • Empty the bladder regularly, as it can helps in preventing hematuria.
  • Wash your hands regularly with soap and water or use a hand sanitizer to prevent the spread of infections.
  • Wear masks, gloves and other protective clothing.
  • Cover sneezes and coughs with a medical mask or tissue or your elbow.
  • Take vaccinations to enhance your immunity to specific diseases.
  • Clean your utensils, linen and surfaces regularly.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Drug Warnings

Do not take Ifos 1gm Injection if you are allergic to any other ingredients present in it. Do not self-administer Ifos 1gm Injection. Before taking Ifos 1gm Injection, talk to your doctor if you have a history of kidney disease, heart diseases, liver diseases,  cystitis, CNS toxicity. Ifos 1gm Injection is not recommended during pregnancy as it may affect the unborn baby. Tell your doctor if you are breastfeeding before taking Ifos 1gm Injection. It is not recommended for use in children under 1 year of age. Ifos 1gm Injection should be used with caution in infections. Because the chances of infections are more in patients receiving this medicine. Hold the chemotherapy and start with broad-spectrum antibiotics if there are any signs and symptoms of fever. Close monitoring of the body temperature and the blood cell count is necessary. Consumption of alcohol is not recommended while receiving this Ifos 1gm Injection as it may increase the risk of adverse effects such as dizziness, drowsiness, abnormal muscle movements, seizures. Ifos 1gm Injection may cause bone marrow suppression, which lowers the white blood cell count (neutrophils) and platelets. Close monitoring of blood cell count is necessary.

Drug-Drug Interactions

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IfosfamideCidofovir
Critical
IfosfamideCladribine
Severe

Drug-Drug Interactions

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IfosfamideCidofovir
Critical
How does the drug interact with Ifos 1gm Injection:
Taking cidofovir with Ifos 1gm Injection can increase the risk of kidney problems.

How to manage the interaction:
Taking Ifos 1gm Injection with Cidofovir together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
IfosfamideCladribine
Severe
How does the drug interact with Ifos 1gm Injection:
Combining Cladribine with Ifos 1gm Injection can increase the risk of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between Ifos 1gm Injection and Cladribine, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
IfosfamideTenofovir alafenamide
Severe
How does the drug interact with Ifos 1gm Injection:
The combined use of Ifos 1gm Injection and Tenofovir alafenamide can increase the risk of kidney problems.

How to manage the interaction:
Taking Ifos 1gm Injection and Tenofovir alafenamide together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
IfosfamideThalidomide
Severe
How does the drug interact with Ifos 1gm Injection:
Taking thalidomide together with Ifos 1gm Injection may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Ifos 1gm Injection together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
IfosfamideBaricitinib
Severe
How does the drug interact with Ifos 1gm Injection:
Coadministration of baricitinib and Ifos 1gm Injection can raise the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Ifos 1gm Injection if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.
IfosfamideClozapine
Severe
How does the drug interact with Ifos 1gm Injection:
Co-administration of Ifos 1gm Injection with Clozapine can increase the risk of neutropenia (low levels of neutrophils in blood).

How to manage the interaction:
Taking Ifos 1gm Injection with Clozapine together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any signs of infection like fever, chills, or a sore throat, or experience discomfort while urinating, it's best to contact a doctor right away. Do not stop using any medications without a doctor's advice.
IfosfamideInfliximab
Severe
How does the drug interact with Ifos 1gm Injection:
Combining Infliximab with Ifos 1gm Injection can speed up the breakdown of Ifos 1gm Injection in the body. This can increase the risk or severity of developing serious infections.

How to manage the interaction:
Co-administration of Ifos 1gm Injection with Infliximab can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you urinate, contact a doctor right away. Don't hesitate to reach out to your doctor if you experience any of these. Do not stop using any medications without a doctor's advice.
IfosfamideTofacitinib
Severe
How does the drug interact with Ifos 1gm Injection:
Taking Ifos 1gm Injection with Tofacitinib may increase the risk of serious infection.

How to manage the interaction:
Taking Tofacitinib with Ifos 1gm Injection together can possibly result in an interaction, but it can be taken if your doctor has advised it. It is important to keep a close eye on your condition. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
IfosfamideLidocaine
Severe
How does the drug interact with Ifos 1gm Injection:
Coadministration of Ifos 1gm Injection with Lidocaine can increase the risk of methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
There may be a possibility of interaction between Ifos 1gm Injection and Lidocaine, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
IfosfamideEtanercept
Severe
How does the drug interact with Ifos 1gm Injection:
When Etanercept is used with Ifos 1gm Injection, the likelihood or severity of infection may increase.

How to manage the interaction:
Although taking Etanercept and Ifos 1gm Injection together can cause an interaction, it can be taken if a doctor has suggested it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a variety of protein-rich foods that are low in fat. Include seafood, lean meat and poultry, greek yoghurts, eggs, beans, soy products, and unsalted nuts and seeds.
  • Take vitamin A foods, found in green- or orange-coloured fruits and vegetables, such as sweet potatoes, carrots, kale, spinach, and apricots.
  • Stay away from strong-smelling foods to avoid aggravating any disorders of taste.
  • Avoid fatty fried, spicy, and overly sweet foods, as they may induce nausea.
  • Avoid refined sugars (including raw, brown, and palm sugar) and refined carbohydrates, as most tumours prefer glucose as an energy source.
  • Avoid drinking alcohol.
  • Quit smoking.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Product Substitutes

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Ifos 1gm Injection contains ‘ifosfamide’, which is an anti-cancer drug. Ifos 1gm Injection works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication. 

Ifos 1gm Injection causes common side effects like nausea, vomiting, anemia (low number of red blood cells), hair loss, decreased white blood cell count, infection, blood in urine, CNS toxicity. Most of these side effects of Ifos 1gm Injection do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

Ifos 1gm Injection is available in the form of injection. Ifos 1gm Injection should be taken as advised by your doctor. Kindly do not self-administer. Your doctor or nurse will give you this medicine.

Yes, Ifos 1gm Injection used in combination with other chemotherapy medicines, radiotherapy, and surgery to treat cancer of blood, breast, lung, ovaries, pancreas, testes, and lymph nodes.

Ifos 1gm Injection may increase the risk of toxic effects on the heart and could lead to congestive heart failure. So Ifos 1gm Injection should be taken as advised by your doctor.

Drug-Drug Interactions Checker List

  • CISPLATIN
  • AMPHOTERICIN B
  • RIFAMPIN
  • DILITAZEM
  • ENALAPRIL
  • CLOZAPINE
  • CARBAMAZEPINE
  • PHENYTOIN
  • PHENOBARBITAL
  • FLUCONAZOLE
  • ITRACONAZOLE
  • KETOCONAZOLE
  • ETANERCEPT
  • ADALIMUMAB

Special Advise

  • Regular monitoring of kidney, liver function, and levels of blood cells in your blood.
  • Drink plenty of fluids while taking this Ifos 1gm Injection to minimize damage to your bladder and kidneys.

Disease/Condition Glossary

Blood cancer:  Blood cancer begins in blood-forming tissue, such as the bone marrow or the immune system's cells. Examples of blood cancer are leukemia ( a blood cancer caused by a rise in the number of white blood cells in your body), lymphoma (cancer that begins in infection-fighting cells of the immune system, called lymphocytes), and multiple myeloma (cancer that forms in a type of white blood cell called a plasma cell). Symptoms include fever, chills., fatigue, weakness, bone and joint pain, weight loss.

Ovarian cancer:  Ovarian cancer is when abnormal cells in the ovary begin to multiply out of control and form a tumor. If left untreated, the tumor can spread to other parts of the body. This is called metastatic ovarian cancer. Symptoms include abdominal bloating, pressure, pain, abnormal fullness after eating, difficulty eating, increased urination, and an increased urge to urinate.

Breast cancer: Cancer that forms in the cells of the breasts. Breast cancer can occur in women and rarely in men. Symptoms of breast cancer include a lump in the breast, bloody discharge from the nipple, and changes in the shape or texture of the nipple or breast.

Testicular cancer: Testicular cancer occurs in the testicles (testes), located inside the scrotum, a loose bag of skin underneath the penis. Symptoms include a painless lump or swelling on either testicle, pain, discomfort, numbness in a testicle or the scrotum, change in the way a testicle feels, or a feeling of heaviness the scrotum, a dull ache in the lower abdomen or groin. Sudden buildup of fluid in the scrotum.

Pancreatic cancer: Pancreatic cancer is cancer that forms in the cells of the pancreas. Pancreatic cancer begins in your pancreas tissues — an organ in your abdomen that lies behind the lower part of your stomach. Your pancreas releases enzymes that aid digestion and produce hormones that help manage your blood sugar. Symptoms include abdominal pain that radiates to your back, loss of appetite or unintended weight loss, yellowing of your skin and the whites of your eyes (jaundice), light-colored stools, dark-colored urine, itchy skin.

Non-small cell lung cancer: Non-small cell lung cancer is a disease in which malignant (cancer) cells form in the lung tissues. There are several types of non-small cell lung cancer. Smoking is the major risk factor for non-small cell lung cancer. Symptoms include a cough that won't go away, shortness of breath, weight loss, or coughing up blood.

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