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Reviewed By Sureshvarma D , MPharma
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Whats That

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Composition

EVEROLIMUS-0.5MG

Manufacturer/Marketer

Novartis India Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Certican 0.5 Tablet 10's

Certican 0.5 Tablet 10's belongs to the group of medicine called ‘anti-cancer’. It is primarily used to treat breast cancer, pancreatic cancer, lung cancer and kidney cancer. Breast cancer is a type of cancer that develops in breast cells stimulated by the female sex hormone known as estrogen. Pancreatic cancer is described as a cancerous growth in the pancreas which normally begins in the cells that generate the juices that help break down food and the hormones which help in controlling blood sugar levels. Lung cancer is the uncontrolled growth of abnormal cells in one or both lungs. 

Certican 0.5 Tablet 10's contains 'Everolimus' which belongs to the group of medicines known as 'kinase inhibitors'. It works by decreases the activity of the immune system of the body and prevents rejection of the transplanted organ. It works by stopping the action of an abnormal protein that causes the multiplication of cancerous cells. In this way, it stops the spread of cancerous cells.

Take Certican 0.5 Tablet 10's as prescribed by your doctor. You are advised to take Certican 0.5 Tablet 10's for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience weakness, infection, sinus inflammation, cough, diarrhea, fever, fatigue, otitis media (infection of the ear), stomatitis (Inflammation of the mouth) and upper respiratory tract infection. Most of these side effects of Certican 0.5 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

To treat your condition effectually, continue taking Certican 0.5 Tablet 10's for as long as your doctor has prescribed. If you are known to be allergic to Certican 0.5 Tablet 10's or any other medicines, please tell your doctor. Do not take Certican 0.5 Tablet 10's if you are pregnant or planning for pregnancy as Certican 0.5 Tablet 10's may harm the unborn baby. Certican 0.5 Tablet 10's should not be taken by breastfeeding mothers as it may cause harm to the newborn baby. Certican 0.5 Tablet 10's causes tiredness, thus, it is advisable not to drive unless you are alert. Elderly people are more sensitive to medicine so they may adjust the dosage according to their condition.

Uses of Certican 0.5 Tablet 10's

Breast cancer, pancreatic cancer, lung cancer and kidney cancer.

Directions for Use

Take Certican 0.5 Tablet 10's with or without food as advised by the doctor. Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Certican 0.5 Tablet 10's is indicated to the patients dealing with breast cancer, pancreatic cancer, lung cancer, kidney cancer and stomach/ intestinal cancer. Cancer of this type tends to spread quickly in other parts of the body. Certican 0.5 Tablet 10's travels through the bloodstream and effectively destroys cancerous cells and other parts of the body. It works by decreases the activity of the immune system of the body and prevents rejection of the transplanted organ. It works by stopping the action of an abnormal protein that causes the multiplication of cancerous cells. In this way, it stops the spread of cancerous cells. Besides this, it is also effective in people with genetic disorders to treat some types of tumors in the brain or kidney.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Certican 0.5 Tablet 10's

  • Tiredness
  • Breathlessness
  • Dizziness
  • Headache
  • Loss of appetite
  • Infection
  • Mouth ulcers 
  • Sinus inflammation
  • Cough
  • Diarrhea
  • Fever
  • High level of sugar in the blood (hyperglycemia)
  • Signs of low level of red blood cells (anemia) 
  • Otitis media (infection of the ear)
  • Stomatitis (Inflammation of the mouth)
  • Upper respiratory tract infection.
  • Swelling of arms, hands, feet, and ankles

Drug Warnings

If you are known to be allergic to Certican 0.5 Tablet 10's or any other medicines, please tell your doctor. Certican 0.5 Tablet 10's should not be taken in the conditions like liver disease, diabetes and high level of cholesterol. Do not take Certican 0.5 Tablet 10's if you have recent surgery, infection and hepatitis B. Certican 0.5 Tablet 10's may weaken your immune system, inform your doctor before taking Certican 0.5 Tablet 10's. Certican 0.5 Tablet 10's may also impair your kidney function. Therefore, monitor your kidney function regularly while taking Certican 0.5 Tablet 10's. Certican 0.5 Tablet 10's may cause cough, fever and shortness of breathing, thereby inform your doctor while taking your Certican 0.5 Tablet 10's. Certican 0.5 Tablet 10's may cause skin cancer, if you observe night sweating, weight loss, or change in color and size of the mole inform your doctor. Do not take Certican 0.5 Tablet 10's if you are pregnant or planning for pregnancy as Certican 0.5 Tablet 10's may harm the unborn baby. Certican 0.5 Tablet 10's should not be taken by breastfeeding mothers as it may cause harm to the newborn baby. Certican 0.5 Tablet 10's causes tiredness, thus, it is advisable not to drive unless you are alert. Elderly people are more sensitive to medicine so they may adjust the dosage according to their condition.

Drug-Drug Interactions

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EverolimusFenoprofen
Severe
EverolimusFingolimod
Severe

Drug-Drug Interactions

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EverolimusFenoprofen
Severe
How does the drug interact with Certican 0.5 Tablet:
Certican 0.5 Tablet can cause kidney issues, and taking it with Fenoprofen, can enhance the risk.

How to manage the interaction:
Taking Certican 0.5 Tablet with Fenoprofen together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not stop using any medications without talking to a doctor.
EverolimusFingolimod
Severe
How does the drug interact with Certican 0.5 Tablet:
When Certican 0.5 Tablet is used with Fingolimod, the likelihood or severity of infection may increase.

How to manage the interaction:
Although there is a possible interaction between Certican 0.5 Tablet and Fingolimod, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EverolimusMifepristone
Severe
How does the drug interact with Certican 0.5 Tablet:
Co-administration of Certican 0.5 Tablet with mifepristone may significantly increase the risk of side effects.

How to manage the interaction:
Taking Certican 0.5 Tablet with mifepristone together can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
EverolimusVerapamil
Severe
How does the drug interact with Certican 0.5 Tablet:
Taking Certican 0.5 Tablet with verapamil may raise Certican 0.5 Tablet blood levels noticeably when using verapamil. This may raise the possibility or intensity of major adverse effects (bleeding, anemia, infections, mouth ulcers, and pneumonitis - lung inflammation).

How to manage the interaction:
Although taking Certican 0.5 Tablet together with Verapamil can result in an interaction, they can be taken together if prescribed by a doctor. Do not stop taking any medication without consulting a doctor.
EverolimusGolimumab
Severe
How does the drug interact with Certican 0.5 Tablet:
When Certican 0.5 Tablet is used with Golimumab, the likelihood or severity of infection may increase.

How to manage the interaction:
There may be a possibility of interaction between Certican 0.5 Tablet and Golimumab, but it can be taken if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EverolimusCeritinib
Severe
How does the drug interact with Certican 0.5 Tablet:
Co-administration of Certican 0.5 Tablet with ceritinib can raise the blood levels of Certican 0.5 Tablet.

How to manage the interaction:
Although there is an interaction between Ceritinib and Certican 0.5 Tablet, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms like persistent cough, fever, chills, mouth ulcers, paleness, mouth sores, bruising, blood in stools, urine and vomitus, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
EverolimusKetoconazole
Severe
How does the drug interact with Certican 0.5 Tablet:
Coadministration of Ketoconazole and Certican 0.5 Tablet may increase the blood levels of Certican 0.5 Tablet. which may develop serious side effects (pneumonitis - inflammation of the lungs, infection, mouth ulcers, anemia, or bleeding).

How to manage the interaction:
Although taking Ketoconazole and Certican 0.5 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Consult a doctor if you experience pneumonitis (inflammation of the lungs), infection, mouth ulcers (painful sores that can appear anywhere in the mouth), anemia (low number of red blood cells), or bleeding. Do not discontinue any medication without consulting a doctor.
EverolimusAnakinra
Severe
How does the drug interact with Certican 0.5 Tablet:
When Certican 0.5 Tablet is coupled with Anakinra, the breakdown of it can be enhanced.

How to manage the interaction:
Although there is a possible interaction between Anakinra and Certican 0.5 Tablet, you can take these medicines together if prescribed by a doctor. Do not discontinue any medications without a doctor's advice.
EverolimusBacitracin
Severe
How does the drug interact with Certican 0.5 Tablet:
Certican 0.5 Tablet can cause kidney issues, and taking it with bacitracin, can enhance the risk.

How to manage the interaction:
Although taking Bacitracin and Certican 0.5 Tablet together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medication without consulting a doctor.
EverolimusFosamprenavir
Severe
How does the drug interact with Certican 0.5 Tablet:
Taking Certican 0.5 Tablet with Fosamprenavir can considerably raise blood levels of Certican 0.5 Tablet, increasing the risk of serious side effects (pneumonitis - lung inflammation, infection, mouth ulcers, anemia, or bleeding).

How to manage the interaction:
Taking Certican 0.5 Tablet with Fosamprenavir together can result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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EVEROLIMUS-0.5MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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EVEROLIMUS-0.5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Taking Certican 0.5 Tablet with grapefruit juice can raise blood levels and enhance the effects of Certican 0.5 Tablet. Since the co-administration of Certican 0.5 Tablet along with grapefruit juice can lead to an interaction, You should not consume grapefruit juice or eat grapefruits while taking Certican 0.5 Tablet.

Diet & Lifestyle Advise

  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yogurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs and spices in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep, rest well.
  • Performing yoga and other relaxation techniques may also improve physical and mental health and may reduce your stress levels.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Certican 0.5 Tablet 10's Substitute

Substitutes safety advice
  • Evergraf 0.5 Tablet 10's

    by Others

    141.35per tablet
  • ADVACAN 0.5MG TABLET

    by Others

    98.55per tablet
  • Lanolimus 0.5 mg Tablet 10's

    by Others

    66.51per tablet
  • Everotas 0.5 mg Tablet 10's

    by Others

    87.39per tablet
  • Ever-Rite 0.5 Tablet 10's

    by Others

    74.25per tablet

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • KETOCONAZOLE
  • ITRACONAZOLE
  • VORICONAZOLE
  • CLARITHROMYCIN
  • TELITHROMYCIN
  • ERYTHROMYCIN
  • RITONAVIR
  • EFAVIRENZ
  • RAMIPRIL
  • VERAPAMIL
  • DILTIAZEM
  • DRONEDARONE
  • IMATINIB
  • PHENYTOIN
  • CARBAMAZEPINE
  • PHENOBARBITAL
  • FLUCONAZOLE

Special Advise

  • Certican 0.5 Tablet 10's should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Certican 0.5 Tablet 10's.
  • Do not have immunizations/vaccinations without a doctor's advice.
  • Avoid contact with people who have recently received live vaccines.

Disease/Condition Glossary

Breast cancer: It is a type of cancer that develops in breast cells that are stimulated by a female sex hormone called estrogen. Breast cancer may form in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), in the fatty tissue or the fibrous connective tissue within the breast. The tumor cells invade other healthy breast cells and can travel to lymph nodes which are a primary pathway for the cancer cells to move to other parts of the body. 

Lung cancer: It happens when cells in the lung begin to grow in an uncontrolled manner. The most common form of lung cancer is non-small cell lung cancer (NSCLC). It happens when cells that form the lining of the lung start growing uncontrollably. Persons who smoke are at high risk of lung cancer. A common symptom of lung cancer is a cough that does not go easily followed by shortness of breath. Cancerous cells of the lung spread off and travel through the bloodstream to distant regions of the body and grow.

Pancreatic cancer: It is described as a cancerous growth in the pancreas which normally begins in the cells that generate the juices. Juices are produced by the pancreas ( a gland present behind your stomach) help in the breakdown of food and hormones which help in controlling blood sugar levels.

Kidney cancer: Kidneys are the organs on either side of your backbone directly above your waist. The tubes present inside clean and filter your blood, taking out waste foods and making urine. Kidney cancer produces in the lining of tiny tubes inside your kidneys.

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