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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About CIDNAVIR 75MG/ML INJ

CIDNAVIR 75MG/ML INJ is an antiviral medicine used in the treatment of cytomegalovirus (CMV) retinitis. Cytomegalovirus (CMV) retinitis is a viral infection that affects the retina of the eye caused by a virus called Cytomegalovirus (CMV), especially in AIDS patients. It is a serious infection that can lead to blindness. CIDNAVIR 75MG/ML INJ is used in combination with oral probenecid.

CIDNAVIR 75MG/ML INJ contains Cidofovir, which works by inhibiting the CMV polymerase enzyme responsible for viral DNA synthesis. It works by slowing the growth of the cytomegalovirus. Thus, it helps treat Cytomegalovirus (CMV) retinitis.

CIDNAVIR 75MG/ML INJ may cause certain side effects such as nausea, vomiting, headache, hair loss, rash, weakness, fever, inflammation of the eye, shortness of breath, diarrhoea, chills, and pain at the injection site. These side effects may not occur in every patient using this medication and gradually resolve over time. If the side effects persist longer or worsen, please inform your doctor. A healthcare professional will administer CIDNAVIR 75MG/ML INJ; hence, do not self-administer.

CIDNAVIR 75MG/ML INJ should be avoided if you are allergic to it. This medicine is contraindicated in patients with renal insufficiency and patients who cannot receive probenecid or other sulfa-containing products. This medicine should not be used for conditions other than CMV retinitis. Let your doctor know about your complete medical and medication history to rule out any interactions. Inform your doctor if you have a weakened immune system, an electrolyte imbalance, diabetes, and liver or kidney diseases before starting the use of CIDNAVIR 75MG/ML INJ. CIDNAVIR 75MG/ML INJ is not recommended for use in pregnant and breastfeeding women.

Uses of CIDNAVIR 75MG/ML INJ

Cytomegalovirus (CMV) retinitis.

Directions for Use

CIDNAVIR 75MG/ML INJ will be administered by a healthcare professional. Do not self-administer.

Medicinal Benefits

CIDNAVIR 75MG/ML INJ treats viral infection of the eye caused by Cytomegalovirus (CMV) retinitis. CIDNAVIR 75MG/ML INJ consists of Cidofovir, which works by inhibiting the CMV polymerase enzyme responsible for viral DNA synthesis. It helps kill the virus and eventually stop the growth of the cytomegalovirus. Thus, helps to treat Cytomegalovirus (CMV) retinitis. This medicine is only used in treating CMV retinitis but is not used for other conditions. It does not help in treating HIV infection.

Storage

Store in a cool and dry place away from sunlight

Side Effects of CIDNAVIR 75MG/ML INJ

  • Nausea
  • Vomiting
  • Diarrhea
  • Tiredness
  • Redness
  • Pain
  • Injection site reactions
  • Shortness of breath
  • Fever
  • Chills
  • Inflammation of eye
  • Hair loss
  • Headache

Drug Warnings

CIDNAVIR 75MG/ML INJ should be avoided if you are allergic to it. Let your doctor know about your medical history and medication history to rule out any interactions. This medicine is contraindicated in patients with renal insufficiency, patients who cannot receive probenecid or other sulfa-containing products, and the use of CIDNAVIR 75MG/ML INJ in conditions other than CMV retinitis. Inform your doctor if you have a weakened immune system, an electrolyte imbalance, diabetes, and liver or kidney diseases before starting CIDNAVIR 75MG/ML INJ. CIDNAVIR 75MG/ML INJ is not recommended for use in pregnant and breastfeeding women. Hence, inform your doctor before starting CIDNAVIR 75MG/ML INJ.  CIDNAVIR 75MG/ML INJ may cause nephrotoxicity, haematological toxicity, decreased intraocular pressure, and metabolic acidosis in some patients. Hence, patients should be monitored carefully for any changes during the treatment. CIDNAVIR 75MG/ML INJ is not recommended for use in children below 16 years of age as the safety and efficacy are not established. Avoid driving and operating machines, as it can cause fatigue and dizziness.

Drug-Drug Interactions

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CidofovirCapreomycin
Critical
CidofovirAmikacin
Critical

Drug-Drug Interactions

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CidofovirCapreomycin
Critical
How does the drug interact with Cidnavir Injection 5 ml:
Taking Cidnavir Injection 5 ml with capreomycin can increase the risk of kidney problems.

How to manage the interaction:
Taking Capreomycin with Cidnavir Injection 5 ml is not recommended, but can be taken if prescribed by a doctor. However, if you experience s nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
CidofovirAmikacin
Critical
How does the drug interact with Cidnavir Injection 5 ml:
Co-administration of Cidnavir Injection 5 ml with Amikacin can increase the risk of developing kidney problems.

How to manage the interaction:
Taking Cidnavir Injection 5 ml with Amikacin is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience vomiting, irregular urination, sudden weight gain or loss, swelling, shortness of breath, muscle cramps, dizziness, or palpitations, consult a doctor immediately. Do not stop using any medications without talking to a doctor.
CidofovirCelecoxib
Critical
How does the drug interact with Cidnavir Injection 5 ml:
Co-administration of Cidnavir Injection 5 ml with Celecoxib can increase the risk of kidney problems.

How to manage the interaction:
Taking Celecoxib with Cidnavir Injection 5 ml is not recommended, please consult your doctor before taking it. However, consult the doctor if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without talking to a doctor.
Cidofovirvalacyclovir
Critical
How does the drug interact with Cidnavir Injection 5 ml:
Taking Cidnavir Injection 5 ml with Valaciclovir can increase the risk of kidney problems.

How to manage the interaction:
Taking valacyclovir with Cidnavir Injection 5 ml is not recommended as it can lead to an interaction, but can be taken together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
CidofovirDeferoxamine
Critical
How does the drug interact with Cidnavir Injection 5 ml:
Co-administration of Deferoxamine and Cidnavir Injection 5 ml may increase the risk of kidney problems.

How to manage the interaction:
Taking Deferoxamine with Cidnavir Injection 5 ml is not recommended, please consult your doctor before taking it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact your doctor immediately. Do not discontinue any medications without consulting a doctor
CidofovirCiclosporin
Critical
How does the drug interact with Cidnavir Injection 5 ml:
Taking cyclosporine with Cidnavir Injection 5 ml can increase the risk of kidney problems.

How to manage the interaction:
Taking Ciclosporin with Cidnavir Injection 5 ml is not recommended, but can be taken be together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact the doctor immediately. Do not discontinue any medications without consulting a doctor
CidofovirLutetium (177lu) oxodotreotide
Critical
How does the drug interact with Cidnavir Injection 5 ml:
Co-administration of Lutetium (177lu) oxodotreotide may increase the risk of kidney problems.

How to manage the interaction:
Taking Lutetium (177lu) oxodotreotide with Cidnavir Injection 5 ml is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without talking to a doctor.
CidofovirLithium
Critical
How does the drug interact with Cidnavir Injection 5 ml:
Cidnavir Injection 5 ml can cause higher levels of Lithium carbonate in the blood which increases risk of kidney problems.

How to manage the interaction:
Taking Lithium with Cidnavir Injection 5 ml is not recommended, but can be taken together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
CidofovirMesalazine
Critical
How does the drug interact with Cidnavir Injection 5 ml:
Co-administration of Mesalazine with Cidnavir Injection 5 ml can increase the risk of kidney problems.

How to manage the interaction:
Taking Mesalazine with Cidnavir Injection 5 ml is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience increased or decreased urination, sudden weight gain or loss, shortness of breath, consult a doctor. Do not discontinue any medications without consulting a doctor.
CidofovirTacrolimus
Critical
How does the drug interact with Cidnavir Injection 5 ml:
Taking Cidnavir Injection 5 ml with tacrolimus can increase the risk of kidney problems.

How to manage the interaction:
Taking Tacrolimus with Cidnavir Injection 5 ml is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor immediately if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Eat foods rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Know your allergy triggers, such as pollen, dust and other factors.
  • Do not rub your eyes even though some ophthalmic drugs make your eye itchy.
  • Try to drink plenty of water to keep your body hydrated.

Habit Forming

No

Therapeutic Class

ANTIVIRALS

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ZIDOVUDINE
  • ADEFOVIR
  • TENOFOVIR
  • PROBENECID
  • FOSCARNET
  • AMPHOTERICIN B
  • VANCOMYCIN
  • PENTAMIDINE

Special Advise

  • CIDNAVIR 75MG/ML INJ is administered only by intravenous route. Direct intraocular injection is not recommended as it can cause visual impairment.
  • Frequent eye tests and regular kidney function tests will be advised to check for any changes.
  • CIDNAVIR 75MG/ML INJ should not be administered in patients who are unable to take probenecid or other sulpha-containing medicines.

Disease/Condition Glossary

Cytomegalovirus (CMV) retinitis: This is an eye infection caused when Cytomegalovirus (CMV) affects the retina (light-sensing nerve layer) of the eye, which can lead to blindness or eye problems. It mainly occurs in weak immune patients, such as AIDS (Acquired immune deficiency syndrome). Symptoms include eye pain, tearing, redness, blurred vision, blind spots and visual disturbances. 

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