CLADRIM 10MG INJECTION

CLADRIM 10MG INJECTION belongs to a group of anticancer medicines called purine analogue used in the treatment of hairy cell leukaemia. Leukaemia, also known as blood cancer, is a cancer of blood cells or blood-forming tissues. It causes excessive production of immature white blood cells by the bone marrow and reduces the body’s ability to fight infections. 

CLADRIM 10MG INJECTION contains Cladribine, which belongs to the class of purine antimetabolites. It works by inhibiting DNA synthesis (responsible for DNA elongation, synthesis, and repair) in cancer cells by interfering with the ribonucleotide reductase and DNA polymerase enzymes.

CLADRIM 10MG INJECTION may cause certain side effects such as insomnia, dizziness, cough, abdominal pain, rash, constipation, fatigue, vomiting, nausea, headache, cough, constipation, weakness, and pain at the site of injection. Most of these side effects of CLADRIM 10MG INJECTION do not require medical attention and gradually resolve over time. A trained healthcare professional will administer CLADRIM 10MG INJECTION. Hence, do not self-administer.

If you are allergic to CLADRIM 10MG INJECTION, inform your doctor and avoid receiving it. Inform your doctor about your complete medical and medication history before starting treatment with CLADRIM 10MG INJECTION. CLADRIM 10MG INJECTION is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Hence, consult your doctor if you are pregnant, planning to become pregnant or breastfeeding. Let the doctor know if you have/had kidney or liver disease, hemolytic anaemia, or severe bone marrow suppression before starting the treatment, as it may worsen your condition. Inform your doctor if you have received any vaccination before starting the treatment.

CLADRIM 10MG INJECTION contains Cladribine, which is used in the treatment of multiple sclerosis. It works by inhibiting DNA synthesis (responsible for DNA elongation, synthesis, and repair) in cancer cells by interfering with the ribonucleotide reductase and DNA polymerase enzymes. Thus, CLADRIM 10MG INJECTION stops the multiplication of abnormal cells and causes the death of cancer cells.

• Nausea
• Abdominal pain
• Constipation
• Weakness
• Injection site reactions
• Pain at the site of injection
• Headache
• Dizziness
• Insomnia
• Anxiety
• Muscle pain
• Rash

If you are allergic to CLADRIM 10MG INJECTION, inform your doctor and avoid receiving it. Inform your doctor about your complete medical and medication history before starting treatment with CLADRIM 10MG INJECTION. CLADRIM 10MG INJECTION is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Hence, consult your doctor if you are pregnant, planning to become pregnant or breastfeeding. Let the doctor know if you have/had kidney or liver disease, haemolytic anaemia, severe bone marrow suppression, thrombocytopenia (low number of platelets), or neutropenia (low white blood cells) before starting the treatment, as it may worsen your condition. If you are about to receive any vaccinations, inform your doctor beforehand, as it may cause infection.

Drug-Drug Interactions: Inform your doctor if you are taking vaccines, OTC medicines, vitamins and herbal supplements.

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Inform your doctor if you have liver or kidney disease, hemolytic anaemia, severe bone marrow suppression, thrombocytopenia, or neutropenia before starting treatment with CLADRIM 10MG INJECTION.

• Maintain a balanced diet including fruits and vegetables rich in nutrients and low-fat proteins like lean meats, fish and poultry.
• Drink plenty of water daily while receiving the medication, as some cancer therapies may cause dehydration.
• Exercise regularly and maintain a healthy body weight.
• Regularly wash your hands and avoid contact with people having infections.
• Quit smoking.

Regular blood tests are recommended while receiving CLADRIM 10MG INJECTION to monitor any signs of anemia, neutropenia and thrombocytopenia.

Hairy cell Leukemia: It is a rare type of cancer that occurs in the bone marrow and blood. It increases the number of lymphocytes (a type of white blood cell). The symptoms include fever, enlarged liver, bone or joint pain, shortness of breath, weakness, and bleeding from gums or bruises.