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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Sunny S , MBBS

Manufacturer/Marketer :

Consume Type :

Oral

Expires on or after :

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About Cloff Dry Syrup

Cloff Dry Syrup belongs to a group of medicine called macrolide antibiotics derived from Saccharopolyspora erythraea (originally called Streptomyces erythreus), used to treat a wide range of bacterial infections, including chest infections such as bronchitis and pneumonia, skin problems such as cellulitis (potentially serious bacterial skin infection. The affected skin appears swollen and red and is typically painful and warm to the touch), and ear infections. Besides this, Cloff Dry Syrup is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori. A bacterial infection is a condition in which bacteria grow in the body and cause infection. It can target any body part and multiple very quickly. Antibiotics inhibit the growth of microorganisms given to treat such kinds of conditions.

Cloff Dry Syrup contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Cloff Dry Syrup helps in the prevention of infections.

Cloff Dry Syrup should only be if your doctor has prescribed you. Cloff Dry Syrup should not be stopped even if you feel better as it is an antibiotic medication, and completing the full course if very necessary; otherwise, the infection might re-appear in a more severe form. Like all medicines, Cloff Dry Syrup may cause some common side effects, including feeling sick (nausea), diarrhoea and being sick (vomiting), losing your appetite, bloating and indigestion, headaches and difficulty sleeping. These side effects are temporary and may get resolve after some time; however, if this side persists, let your doctor know about this if you notice any sudden wheeziness, tightness in the chest or throat, difficulty in breathing, swelling of the eyelids, face or lips, rash or itching (especially affecting your whole body) STOP TAKING your medicine and go to a doctor immediately.

Do not take Cloff Dry Syrup if allergic to azithromycin, other macrolide antibiotics, or any components present in Cloff Dry Syrup. Cloff Dry Syrup isn't normally recommended during pregnancy and while breastfeeding. But your doctor may prescribe it if the benefits of you taking it are greater than the risks. Do not consume alcohol as it may cause excessive drowsiness when taken along with Cloff Dry Syrup. Before using the Cloff Dry Syrup, tell your doctor if you ever had an allergy to Cloff Dry Syrup have kidney problems, liver problems, swollen food pipe (oesophagitis), lupus disease (an autoimmune disease), or muscle disease (myasthenia gravis). Do not drink alcohol with Cloff Dry Syrup as it may increase the unpleasant side effects like drowsiness and dizziness.

Uses of Cloff Dry Syrup

Bacterial infections

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Directions for Use

Tablet/capsule: Swallow it as a whole with water; do not crush, break or chew it. Dispersible Tablet: Check the label for directions before use. Disperse the tablet in the prescribed amount of water and swallow the contents. Do not crush, chew or swallow as a whole. Oral Suspension/Syrup: Shake the bottle well before use. Check the label for directions and take Cloff Dry Syrup in doses as prescribed by your doctor with the help of a measuring cup. Powder/granules: Check the label for directions before use. Mix the powder/granules in water, mix well and drink immediately.

Key Benefits

Cloff Dry Syrup is a type of macrolide class of antibiotic which is effective against a wide range of bacteria, including gram-negative, gram-positive bacteria, anaerobes, and some parasites (like Balantidium coli and Entamoeba species). It is prescribed for treating various bacterial infections including chest infections such as pneumonia, skin problems such as cellulitis, and ear infections; on the other hand, It is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori (Helicobacter pylori). Cloff Dry Syrup is sometimes used by people who have an allergy to penicillin and antibiotics similar to penicillin, such as amoxicillin.

Storage

Store in a cool and dry place away from sunlight
Side effects of Cloff Dry Syrup 30 ml
  • Regularly brush and floss your teeth.
  • Rinse your mouth with water and baking soda a solution to neutralize acid in the mouth. This makes your food taste as it should.
  • Drink plenty of water or non-caffeinated drinks to prevent dry mouth which may lead to altered taste.
  • Try ginger, peppermint, fruit or green teas, lemonade, ginger ale or fruit juice to help mask unpleasant tastes.
  • Try sucking on sugar-free ice pops or ice cubes to prevent dry mouth.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Drug Warnings

Iron and antacid (like magnesium hydroxide and aluminium hydroxide) may bind to Cloff Dry Syrup in the gastrointestinal tract, lowering its efficiency. So, a gap of at least 2 hours should be maintained between intake of Cloff Dry Syrup and iron supplements and antacids. Besides this, in some cases, the use of Cloff Dry Syrup causes antibiotic-associated diarrhoea. Cloff Dry Syrup may cause sensitive skin to sunlight and ultraviolet rays, causing an exaggerated sunburn reaction. Hence it is advisable to apply sunscreen before going outside. Its use has also been associated with an increased risk of fungal skin infections like (vaginal candidiasis - thrush). Tetracycline and Cloff Dry Syrup can form a stable calcium complex in bone-forming tissue, thereby affecting the growth of fibula bones in young children and bone development in the foetus. Using a Cloff Dry Syrup with isotretinoin should be avoided as it has been reported to cause pseudotumor cerebri (increased pressure inside the brain). Long-term use of Cloff Dry Syrup may affect your blood, kidney, and liver health, so yearly diagnostics test of these parameters is recommended.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Cloff Dry Syrup 30 ml:
Taking Cloff Dry Syrup 30 ml with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Co-administration of Cloff Dry Syrup 30 ml and Ziprasidone can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Cloff Dry Syrup 30 ml:
When Cabergoline is taken with Cloff Dry Syrup 30 ml, the amount of Cabergoline in the blood can go up.

How to manage the interaction:
Taking Cabergoline with Cloff Dry Syrup 30 ml is not recommended, please consult your doctor before taking it. They can be taken together if advised by your doctor. However, contact your doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
Critical
How does the drug interact with Cloff Dry Syrup 30 ml:
When Naloxegol is taken with Cloff Dry Syrup 30 ml, the amount of Naloxegol in the blood can go up.

How to manage the interaction:
Co-administration of Cloff Dry Syrup 30 ml and Naloxegol can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like sweating, tearing, runny nose, chills, diarrhea, abdominal pain, anxiety, insomnia, irritability, restlessness, and yawning, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinMesoridazine
Critical
How does the drug interact with Cloff Dry Syrup 30 ml:
Co-administration of Cloff Dry Syrup 30 ml and Mesoridazine may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Cloff Dry Syrup 30 ml and Mesoridazine can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinVenetoclax
Critical
How does the drug interact with Cloff Dry Syrup 30 ml:
When Venetoclax is taken with Cloff Dry Syrup 30 ml, the body's ability to break down Venetoclax may be reduced.

How to manage the interaction:
Taking Cloff Dry Syrup 30 ml with Venetoclax is not recommended, please consult your doctor before taking it.
ClarithromycinFlibanserin
Critical
How does the drug interact with Cloff Dry Syrup 30 ml:
When Flibanserin is taken with Cloff Dry Syrup 30 ml, it can slow down the way Flibanserin is broken down in the body.

How to manage the interaction:
Co-administration of Cloff Dry Syrup 30 ml and Flibanserin can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like excessive drowsiness and decreases in blood pressure that can lead to dizziness, lightheadedness, or fainting, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinAstemizole
Critical
How does the drug interact with Cloff Dry Syrup 30 ml:
When Astemizole is taken with Cloff Dry Syrup 30 ml, it can cause a decrease in the metabolism of Astemizole.

How to manage the interaction:
Taking Cloff Dry Syrup 30 ml with Astemizole is not recommended, please consult your doctor before taking it.
How does the drug interact with Cloff Dry Syrup 30 ml:
When Ranolazine and Cloff Dry Syrup 30 ml are taken together, significantly increases the blood levels and effects of Ranolazine.

How to manage the interaction:
Co-administration of Cloff Dry Syrup 30 ml and Ranozaline can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
ClarithromycinDihydroergotamine
Critical
How does the drug interact with Cloff Dry Syrup 30 ml:
When Dihydroergotamine is taken with Cloff Dry Syrup 30 ml, the amount of Dihydroergotamine in the blood can go up.

How to manage the interaction:
Taking Cloff Dry Syrup 30 ml with Dihydroergotamine can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, and/or slurred speech, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Cloff Dry Syrup 30 ml:
Combining Cloff Dry Syrup 30 ml with Thioridazine can increase the risk of irregular heart rhythm.

How to manage the interaction:
Co-administration of Cloff Dry Syrup 30 ml and Thioridazine can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Probiotics and prebiotics can also help to reduce the side effects of antibiotics.
  • Include more fibre-enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread and brown rice should be included in your diet. 
  • Eating grapefruit during antibiotics treatment can prevent the body from utilizing Cloff Dry Syrup properly. So, avoid intake of grapefruit or grapefruit juice with the antibiotic. 
  • Avoid taking too much calcium, iron-enriched foods and drinks as it might affect the working of Cloff Dry Syrup. 
  • Avoid intake of alcoholic beverages with Cloff Dry Syrup as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Cloff Dry Syrup in fighting off infections.

Habit Forming

No

Therapeutic Class

[ANTI- BACTERIALS]

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Alcohol

Safe if prescribed

Cloff Dry Syrup should not be taken until prescribed if you are taking alcohol. Keep your doctor informed if you drink alcohol.

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Pregnancy

Consult your doctor

Cloff Dry Syrup should be used in pregnant women only if clinically needed, and the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Let your doctor know if you are a nursing mother before taking Cloff Dry Syrup; your doctor will decide whether Cloff Dry Syrup can be taken by breastfeeding mothers or not.

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Driving

Safe if prescribed

Not enough scientific data available for Cloff Dry Syrup, hence it is advised to consult your doctor.

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Liver

Consult your doctor

Cloff Dry Syrup to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Consult your doctor

Cloff Dry Syrup to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Safe if prescribed

Cloff Dry Syrup can be given safely to children in the form of suspension only, dose to be adjusted and recommended by a child specialist only.

FAQs

Cloff Dry Syrup contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Cloff Dry Syrup helps in the prevention of infections.

You should avoid taking iron supplements, multivitamins, calcium supplements, antacids, or laxatives within 2 hours before or after taking Cloff Dry Syrup. Avoid taking any other antibiotics containing Cloff Dry Syrup unless your doctor has prescribed you.

After taking antibiotics such as Cloff Dry Syrup, some people get thrush, a fungal infection. This is due to the fact that antibiotics kill the regular, harmless bacteria that serve to protect you from thrush.

Cloff Dry Syrup treats only bacterial infections. It will not work for viral infections (such as common cold, flu).

No, Cloff Dry Syrup is a macrolide antibiotic. It can be taken by people who are allergic to penicillin with doctor advice only.

Side-effects are rare with Cloff Dry Syrup and do not usually last long. They will get better after a day or two. if those side effects persist reach out to the doctor immediately.​

No, Cloff Dry Syrup should not be stopped even if you feel better as it is an antibiotic medication and completing the full course if very necessary; otherwise, the infection might re-appear in a more severe form.

Country of origin

India

Manufacturer/Marketer address

Alembic Road, Vadodara - 390 003, Gujarat,INDIA.
Other Info - CLO1038

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