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Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS

About Clofranil SR 50 Tablet 10's

Clofranil SR 50 Tablet 10's belongs to a class of drugs called 'antidepressant' used to treat obsessive-compulsive disorder (OCD), depression, panic and anxiety disorder. OCD is a mental disorder with symptoms such as excessive thoughts or ideas (obsessions), leading to repetitive behaviours (compulsions). Depression is a mood disorder associated with symptoms such as sadness, unable to sleep properly or enjoy life as you used to do. Panic or anxiety disorder is linked to anxiety with sudden feelings of unnecessary fear or worries even when there is no danger in reality.

Clofranil SR 50 Tablet 10's contains Clomipramine which works by increasing the activity of serotonin and noradrenaline (chemical messengers) in the brain involved in regulating mood, behaviour and emotions. Thereby, Clofranil SR 50 Tablet 10's helps relieve depression, lighten the mood and relieve anxiety symptoms such as fear and panic.

Take Clofranil SR 50 Tablet 10's with food as prescribed by your doctor and swallow whole with a glass of water. Do not break, crush or chew it. Your doctor will advise you how often you take Clofranil SR 50 Tablet 10's based on your medical condition. Some people may experience dizziness, headache, drowsiness, dry mouth, nausea, weight gain, increased sweating, constipation, shaking, blurred vision, erectile dysfunction or difficulty in urination. Most of these side effects of Clofranil SR 50 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Clofranil SR 50 Tablet 10's or any other medicines, please tell your doctor. Clofranil SR 50 Tablet 10's is not recommended for children below 17 years of age. Avoid taking Clofranil SR 50 Tablet 10's if you are pregnant as it may cause harm to the foetus. Avoid breastfeeding while taking Clofranil SR 50 Tablet 10's as it may be excreted in human milk and cause adverse effects in the baby. If you have any self-harming or suicidal thoughts before taking Clofranil SR 50 Tablet 10's, inform your doctor as they may worsen in the initial days of taking Clofranil SR 50 Tablet 10's.

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Non returnable*
COD available

Online payment accepted

Consume Type

ORAL

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of Clofranil SR 50 Tablet 10's

Obsessive-compulsive disorder (OCD), Depression, Panic disorder, Anxiety disorder

Medicinal Benefits

Clofranil SR 50 Tablet 10's contains Clomipramine, an antidepressant used to treat obsessive-compulsive disorder (OCD), depression, and panic disorder. Clofranil SR 50 Tablet 10's increases the activity of serotonin and noradrenaline (chemical messengers) in the brain that are involved in regulating mood, behavior, and emotions. Thereby, Clofranil SR 50 Tablet 10's helps in relieving depression, lighten the mood and relieve anxiety symptoms such as fear and panic. Clofranil SR 50 Tablet 10's in combination with other medicines may be used to treat cataplexy (a disorder that causes muscle weakness) which usually affects people suffering from narcolepsy (uncontrollable sleepiness during daytime).

Side Effects of Clofranil SR 50 Tablet 10's

  • Dizziness
  • Headache
  • Drowsiness
  • Dry mouth
  • Nausea
  • Weight gain
  • Increased sweating
  • Constipation
  • Shaking
  • Blurred vision
  • Erectile dysfunction
  • Difficulty in urination

Directions for Use

Take Clofranil SR 50 Tablet 10's with food or as advised by a doctor. Swallow it as a whole with a glass of water. Do not break, crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to Clofranil SR 50 Tablet 10's or any other medicines, please tell your doctor. Clofranil SR 50 Tablet 10's is not recommended for children below 17 years of age. Avoid taking Clofranil SR 50 Tablet 10's if you are pregnant as it may cause harm to the fetus. Avoid breastfeeding while taking Clofranil SR 50 Tablet 10's as Clofranil SR 50 Tablet 10's may be excreted in human milk and cause adverse effects in the baby. Therefore, please consult a doctor if you are pregnant, planning for pregnancy, or breastfeeding. Clofranil SR 50 Tablet 10's should be used with caution in elderly patients as there is an increased risk of low sodium levels in the blood.  If you have any self-harming or suicidal thoughts before taking Clofranil SR 50 Tablet 10's, inform your doctor as they may worsen in the initial days of taking Clofranil SR 50 Tablet 10's. Do not take Clofranil SR 50 Tablet 10's with monoamine oxidase inhibitors (MAOIs) such as moclobemide, tranylcypromine and phenelzine used to treat depression as it may cause severe adverse effects. Also, avoid taking Clofranil SR 50 Tablet 10's with buprenorphine as it may cause a serious life-threatening condition. If you have fits, low blood pressure, mania, glaucoma, difficulty in urination, a blood disorder, hyperthyroidism (overactive thyroid gland), severe constipation, pheochromocytoma (tumor of the adrenal gland), low potassium levels in blood, kidney, liver, or heart problems, inform your doctor before taking Clofranil SR 50 Tablet 10's.

Therapeutic Class

ANTIDEPRESSANT

Drug-Drug Interactions

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ClomipramineSaquinavir
Critical
ClomipramineSafinamide
Critical

Drug-Drug Interactions

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ClomipramineSaquinavir
Critical
How does the drug interact with Clofranil SR 50 Tablet 10's:
When Clofranil SR 50 Tablet 10's is taken with Saquinavir, can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
There may be a possibility of interaction between Clofranil SR 50 Tablet 10's and Saquinavir, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
ClomipramineSafinamide
Critical
How does the drug interact with Clofranil SR 50 Tablet 10's:
Taking Safinamide with Clofranil SR 50 Tablet 10's can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Clofranil SR 50 Tablet 10's with Safinamide can possibly result in an interaction but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination (seeing and hearing things that do not exist), increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
ClomipramineHalofantrine
Critical
How does the drug interact with Clofranil SR 50 Tablet 10's:
When Clofranil SR 50 Tablet 10's is taken with Halofantrine, can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
There may be a possibility of interaction between Clofranil SR 50 Tablet 10's and Halofantrine, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
ClomipramineProcarbazine
Critical
How does the drug interact with Clofranil SR 50 Tablet 10's:
When Clofranil SR 50 Tablet 10's is taken with Procarbazine, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
There may be a possibility of interaction between Clofranil SR 50 Tablet 10's and Procarbazine, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea-call a doctor right away. Do not stop using any medications without a doctor's advice.
ClomipraminePhenelzine
Critical
How does the drug interact with Clofranil SR 50 Tablet 10's:
When Clofranil SR 50 Tablet 10's is taken with Phenelzine, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
There may be a possibility of interaction between Clofranil SR 50 Tablet 10's and Phenelzine, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea-call a doctor right away. Do not stop using any medications without a doctor's advice.
ClomipramineDronedarone
Critical
How does the drug interact with Clofranil SR 50 Tablet 10's:
When Clofranil SR 50 Tablet 10's is taken with Dronedarone, can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
There may be a possibility of interaction between Clofranil SR 50 Tablet 10's and Dronedarone, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
ClomipramineIsocarboxazid
Critical
How does the drug interact with Clofranil SR 50 Tablet 10's:
When Clofranil SR 50 Tablet 10's is taken with Isocarboxazid, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
There may be a possibility of interaction between Clofranil SR 50 Tablet 10's and Isocarboxazid, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea-contact a doctor immediately. Do not stop using any medications without a doctor's advice.
ClomipramineZiprasidone
Critical
How does the drug interact with Clofranil SR 50 Tablet 10's:
Coadministration of Clofranil SR 50 Tablet 10's with Ziprasidone can increase the risk of irregular heat rhythm.

How to manage the interaction:
Taking Clofranil SR 50 Tablet 10's with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
ClomipramineBepridil
Critical
How does the drug interact with Clofranil SR 50 Tablet 10's:
When Clofranil SR 50 Tablet 10's is taken with Bepridil, can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
There may be a possibility of interaction between Clofranil SR 50 Tablet 10's and Bepridil, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
ClomipramineLinezolid
Critical
How does the drug interact with Clofranil SR 50 Tablet 10's:
When Clofranil SR 50 Tablet 10's is taken with Linezolid, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
There may be a possibility of interaction between Clofranil SR 50 Tablet 10's and Linezolid, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea-contact a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • SELEGILINE
  • LEVODOPA
  • PENTAMIDINE
  • RIFAMPICIN
  • PIMOZIDE
  • BUPRENORPHINE
  • MORPHINE
  • CODEINE
  • WARFARIN
  • MOCLOBEMIDE
  • PHENELZINE
  • TRANYLCYPROMINE
  • FLUVOXAMINE
  • FLUOXETINE
  • AMITRIPTYLINE
  • SERTRALINE
  • VENLAFAXINE
  • DOTHIEPIN
  • LITHIUM
  • PHENYTOIN
  • CARBAMAZEPINE
  • PHENOBARBITAL
  • VALPROATE
  • ASPIRIN
  • CIMETIDINE
  • FUROSEMIDE
  • TERFENADINE
  • RESERPINE
  • GUANETHIDINE
  • CLONIDINE
  • ISOPRENALINE
  • AMIODARONE
  • QUINIDINE
  • DISOPYRAMIDE
  • PROCAINAMIDE
  • EPINEPHRINE
  • DILTIAZEM
  • VERAPAMIL
  • RITONAVIR
  • INDINAVIR
  • MAPROTILINE
  • BETANIDINE

Diet & Lifestyle Advise

  • Maintain a diet rich in fruits, vegetables, and whole grains. Avoid fried foods, high-fat dairy products, pastries, and processed foods as they may worsen anxiety. Include foods rich in omega fatty acids such as fish, nuts, fresh fruits, vegetables, and olive oils.
  • Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help in proper maintenance of neurotransmitters.
  • Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges, and pears.
  • Exercising helps in the production of the body’s natural antidepressants. It also helps in relieving stress, improving mood, boosting self-esteem, and providing restful sleep.
  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.
  • Regularly attend therapy sessions.
  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Special Advise

  • Regular blood tests are recommended while taking Clofranil SR 50 Tablet 10's to monitor liver and heart functioning.
  • Regular dental check-ups are also advised while taking Clofranil SR 50 Tablet 10's as it may cause dry mouth, which may increase the risk of tooth decay.

Author Details

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Disease/Condition Glossary

Obsessive-compulsive disorder (OCD): It is a mental disorder with symptoms such as excessive thoughts or ideas (obsessions) leading to repetitive behaviors (compulsions).

Depression: It is a mood disorder associated with symptoms such as sadness, unable to sleep properly, or enjoy life as you used to do. Depression can also influence some chronic health conditions and relationships. The exact cause of depression is unknown, but it may be associated with mental problems, trauma, family history, drug use, and medical conditions.

Panic disorder: It is linked to anxiety with sudden feelings of fear when there is no danger in reality.

Clofranil SR 50 Tablet 10's Substitute

Substitutes safety advice
  • Clonil-50 Tablet 15's

    17.88per tablet
  • Clofranil 50 Tablet 10's

    16.56per tablet
  • Clomilent 50mg Tablet 10's

    11.25per tablet
  • Clomidep 50 Tablet 10's

    11.52per tablet
  • D.D.Pramine 50mg Tablet 10's

    by AYUR

    14.31per tablet
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