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Reviewed By Sureshvarma D , MPharma

About CO-Trimoxazole DS Tablet 16's

CO-Trimoxazole DS Tablet 16's belongs to the group of medicines called antibiotics used to treat and prevent lung infections caused by a bacteria called Pneumocystis jirovecii, infections caused by a bacteria called Toxoplasma, urinary tract infections (water infections), respiratory tract infections such as bronchitis, ear infections such as otitis media. Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. CO-Trimoxazole DS Tablet 16's does not work against infections caused by the virus, including cold and flu.

CO-Trimoxazole DS Tablet 16's contains Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. Tetrahydrofolic acid and dihydrofolic acid are essential for the formation of proteins and nucleic acids, which are necessary for the survival of bacteria. By inhibiting these, CO-Trimoxazole DS Tablet 16's kills the bacteria and stops their growth. Thereby, it helps to treat bacterial infections.

Take CO-Trimoxazole DS Tablet 16's as prescribed by your doctor. The dose and duration of CO-Trimoxazole DS Tablet 16's can vary depending on your condition and the severity of the infection. In some cases, you may experience certain common side effects such as headache, diarrhoea, skin rashes, nausea, vomiting, heart problems, fever, convulsions or seizures, blood or cloudiness in your urine, hallucinations, and mouth ulcers. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before starting CO-Trimoxazole DS Tablet 16's, please inform your doctor if you have any allergy (against any antibiotic), or kidney or liver problems. Do not take CO-Trimoxazole DS Tablet 16's on your own as self-medication may lead to antibiotic resistance in which antibiotics fail to act against specific bacterial infections. Consult your doctor before taking CO-Trimoxazole DS Tablet 16's if you are pregnant or breastfeeding. Avoid alcohol consumption to prevent unpleasant side effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, and vomiting. CO-Trimoxazole DS Tablet 16's should not be given to children below 12 years. Keep your doctor informed about all the medicines you are taking and your health condition to rule out any unpleasant side effects. Also, it is recommended to complete the course of medicine even if you feel better, as it is an antibiotic. Leaving it in between may lead to even severe infection that will, in fact, stop responding to the antibiotic (antibiotic resistance).

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Non returnable*
COD available

Online payment accepted

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

Uses of CO-Trimoxazole DS Tablet 16's

Bacterial infections

Medicinal Benefits

CO-Trimoxazole DS Tablet 16's belongs to the group of medicines called ‘antibiotics’ used to treat various bacterial infections of the urinary tract, respiratory tract (bronchitis), ear (otitis media), lungs (pneumonia), skin, brain, and toxoplasmosis (infection caused by a bacteria called toxoplasma). CO-Trimoxazole DS Tablet 16's contains Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. Tetrahydrofolic acid and dihydrofolic acid are essential for the formation of proteins and nucleic acids, which are necessary for the survival of bacteria. By inhibiting these, CO-Trimoxazole DS Tablet 16's kills the bacteria and stops their growth. Thereby, it helps to treat bacterial infections. CO-Trimoxazole DS Tablet 16's is a broad-spectrum antibiotic that is active against a wide range of gram-positive and gram-negative bacteria such as Streptococcus pneumonia, Escherichia coli, Klebsiella species, Enterobacter species, Haemophilus influenzae, etc.

Side Effects of CO-Trimoxazole DS Tablet 16's

  • Mouth ulcers
  • Headache
  • Mouth ulcers
  • Diarrhea
  • Blood or cloudiness in your urine
  • Depression
  • Tingling or numbness in your hands and feet
  • Hallucinations

Directions for Use

Tablet: Take it as advised by your doctor. Swallow it as a whole with water; do not crush, break or chew it.Syrup: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack. The dose and duration can vary depending on your condition and the severity of the infection.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take CO-Trimoxazole DS Tablet 16's if you are allergic to any of its contents if you have severe liver or kidney problems, thrombocytopenia (low levels of platelets in the blood), or porphyria (rare blood problem that affects the skin or nervous system). Do not take CO-Trimoxazole DS Tablet 16's on your own, as self-medication may lead to antibiotic resistance in which antibiotics fail to act against specific bacterial infections. Consult your doctor immediately if you experience skin rash or prolonged, significant diarrhoea with abdominal pains. Talk to your doctor before taking CO-Trimoxazole DS Tablet 16's if you have severe allergies, asthma, ulcers, blood disorders, thyroid dysfunction, diabetes, are elderly, underweight, or malnourished if you have a folic acid deficiency, glucose-6-phosphate dehydrogenase deficiency, or high levels of potassium in the blood. Avoid taking CO-Trimoxazole DS Tablet 16's if you are pregnant or breastfeeding unless prescribed by a doctor. Avoid alcohol consumption while taking CO-Trimoxazole DS Tablet 16's to prevent unpleasant side-effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, and vomiting. CO-Trimoxazole DS Tablet 16's will not treat a viral infection. Drink plenty of fluids to prevent kidney stones while taking CO-Trimoxazole DS Tablet 16's.

Therapeutic Class

ANTIBIOTICS

Drug-Drug Interactions

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TrimethoprimBCG vaccine
Critical
TrimethoprimCaptopril
Severe

Drug-Drug Interactions

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TrimethoprimBCG vaccine
Critical
How does the drug interact with CO-Trimoxazole DS Tablet 16's:
Taking CO-Trimoxazole DS Tablet 16's with BCG vaccine can reduce the effectiveness of the BCG vaccine

How to manage the interaction:
Although there is an interaction between CO-Trimoxazole DS Tablet 16's and BCG vaccine is not recommended, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
TrimethoprimCaptopril
Severe
How does the drug interact with CO-Trimoxazole DS Tablet 16's:
Taking captopril with CO-Trimoxazole DS Tablet 16's may increase the risk of hyperkalemia (high level of potassium in the blood) and kidney problems.

How to manage the interaction:
Although there is a interaction between CO-Trimoxazole DS Tablet 16's and captopril, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
TrimethoprimProcaine
Severe
How does the drug interact with CO-Trimoxazole DS Tablet 16's:
Co-administration of CO-Trimoxazole DS Tablet 16's with procaine may increase the risk of blood disorders.

How to manage the interaction:
Taking CO-Trimoxazole DS Tablet 16's with Procaine together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms like gray skin, feeling sick, headache, dizziness, tiredness, trouble breathing, fast heartbeat, or feeling anxious or confused, contact your doctor right away. Do not stop using any medications without talking to your doctor.
TrimethoprimPotassium gluconate
Severe
How does the drug interact with CO-Trimoxazole DS Tablet 16's:
Taking potassium gluconate with CO-Trimoxazole DS Tablet 16's can increase the risk of high potassium levels in the blood.

How to manage the interaction:
Although there is a possible interaction between CO-Trimoxazole DS Tablet 16's and Potassium gluconate, you can take these medicines together if prescribed by your doctor. However, if you are feeling sick, feeling weak, confused, or having a weak or irregular heartbeat contact your doctor immediately. Do not stop using any medications without talking to your doctor.
TrimethoprimRopivacaine
Severe
How does the drug interact with CO-Trimoxazole DS Tablet 16's:
Using ropivacaine with CO-Trimoxazole DS Tablet 16's can cause higher levels of CO-Trimoxazole DS Tablet 16's in the blood.

How to manage the interaction:
Although taking Ropivacaine and CO-Trimoxazole DS Tablet 16's together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion contact your doctor immediately. Do not stop using any medications without a doctor's advice.
TrimethoprimPotassium acetate
Severe
How does the drug interact with CO-Trimoxazole DS Tablet 16's:
Taking potassium acetate with CO-Trimoxazole DS Tablet 16's may increase potassium levels in the blood which can increase the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between CO-Trimoxazole DS Tablet 16's and Potassium acetate, you can take these medicines together if prescribed by your doctor. However, if you have unusual symptoms contact your doctor right away. Do not discontinue any medications without consulting your doctor.
TrimethoprimFosphenytoin
Severe
How does the drug interact with CO-Trimoxazole DS Tablet 16's:
Taking fosphenytoin with CO-Trimoxazole DS Tablet 16's may increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between fosphenytoin and CO-Trimoxazole DS Tablet 16's, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience, weakness, vomiting, blurry vision, or trouble speaking. Do not discontinue any medications without consulting a doctor.
TrimethoprimCandesartan
Severe
How does the drug interact with CO-Trimoxazole DS Tablet 16's:
Taking CO-Trimoxazole DS Tablet 16's with candesartan can increase the risk of hyperkalemia (high potassium levels in the blood) and kidney problems.

How to manage the interaction:
Although there is an interaction between candesartan and CO-Trimoxazole DS Tablet 16's, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
TrimethoprimMethotrexate
Severe
How does the drug interact with CO-Trimoxazole DS Tablet 16's:
Coadministration of CO-Trimoxazole DS Tablet 16's with methotrexate can increase the risk or severity of blood disorders.

How to manage the interaction:
Although there is a possible interaction between CO-Trimoxazole DS Tablet 16's and methotrexate, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as pale skin, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not stop using any medications without consulting to a doctor.
TrimethoprimIrbesartan
Severe
How does the drug interact with CO-Trimoxazole DS Tablet 16's:
Taking Irbesartan with CO-Trimoxazole DS Tablet 16's may increase potassium levels in the blood and kidney problems.

How to manage the interaction:
Although taking Irbesartan with CO-Trimoxazole DS Tablet 16's together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, consult your doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, or a slow or irregular heartbeat. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • AMANTADINE
  • CYCLOSPORINE
  • INDOMETHACIN
  • LEUCOVORIN
  • METHOTREXATE
  • PYRIMETHAMINE
  • BENAZEPRIL
  • QUINAPRIL
  • ENALAPRIL
  • LISINOPRIL
  • RAMIPRIL
  • CHLORTHALIDONE
  • HYDROCHLOROTHIAZIDE
  • WARFARIN

Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach, which helps in digestion. Therefore, you are advised to take foods rich in probiotics, such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk natto, and cheese.
  • Eat fiber-rich food like whole grains, beans, lentils, berries, broccoli, peas, and bananas.
  • Avoid foods rich in calcium, grapefruit, and grapefruit juice, as they might hinder antibiotic absorption.
  • Avoid the consumption of alcohol to treat your condition effectively.
  • Avoid the usage of tobacco.
  • To cure your condition, effectually complete the full course of CO-Trimoxazole DS Tablet 16's even though you find symptomatic relief.

Habit Forming

No

Special Advise

  • CO-Trimoxazole DS Tablet 16's may affect certain laboratory test results, such as blood tests. Inform the person doing the tests that you are taking CO-Trimoxazole DS Tablet 16's. Your doctor may advise you to get regular tests if you have kidney problems or if you have been prescribed CO-Trimoxazole DS Tablet 16's for a longer duration to know if the medicine is working properly.

Disease/Condition Glossary

Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect our body. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. It can target any body part and multiply very quickly. When you get infected with bacteria, you can experience generalized symptoms like fevers, chills, and fatigue. Bacteria are of various forms comprising, commonly spherical, rod, and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. Anyone can become infected with a bacterial infection. But, people with weak immune systems or taking immunosuppressive medicine are more prone to bacterial infection.

CO-Trimoxazole DS Tablet 16's Substitute

Substitutes safety advice
  • Cotrimoxazole DS Tablet 10's

    by AYUR

    2.52per tablet
  • Viktrim DS Tablet 10's

    2.70per tablet
  • Co-Trimoxazole Double Strength Tablet 10's

    1.28per tablet
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