CO-Trimoxazole DS Tablet 16's

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Reviewed By Sureshvarma D , MPharma

MRP ₹56

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Whats That

About CO-Trimoxazole DS Tablet

CO-Trimoxazole DS Tablet belongs to the group of medicines called antibiotics used to treat and prevent lung infections caused by a bacteria called Pneumocystis jirovecii, infections caused by a bacteria called Toxoplasma, urinary tract infections (water infections), respiratory tract infections such as bronchitis, ear infections such as otitis media. Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. CO-Trimoxazole DS Tablet does not work against infections caused by the virus, including cold and flu.

CO-Trimoxazole DS Tablet contains Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. Tetrahydrofolic acid and dihydrofolic acid are essential for the formation of proteins and nucleic acids, which are necessary for the survival of bacteria. By inhibiting these, CO-Trimoxazole DS Tablet kills the bacteria and stops their growth. Thereby, it helps to treat bacterial infections.

Take CO-Trimoxazole DS Tablet as prescribed by your doctor. The dose and duration of CO-Trimoxazole DS Tablet can vary depending on your condition and the severity of the infection. In some cases, you may experience certain common side effects such as headache, diarrhoea, skin rashes, nausea, vomiting, heart problems, fever, convulsions or seizures, blood or cloudiness in your urine, hallucinations, and mouth ulcers. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before starting CO-Trimoxazole DS Tablet , please inform your doctor if you have any allergy (against any antibiotic), or kidney or liver problems. Do not take CO-Trimoxazole DS Tablet on your own as self-medication may lead to antibiotic resistance in which antibiotics fail to act against specific bacterial infections. Consult your doctor before taking CO-Trimoxazole DS Tablet if you are pregnant or breastfeeding. Avoid alcohol consumption to prevent unpleasant side effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, and vomiting. CO-Trimoxazole DS Tablet should not be given to children below 12 years. Keep your doctor informed about all the medicines you are taking and your health condition to rule out any unpleasant side effects. Also, it is recommended to complete the course of medicine even if you feel better, as it is an antibiotic. Leaving it in between may lead to even severe infection that will, in fact, stop responding to the antibiotic (antibiotic resistance).

Uses of CO-Trimoxazole DS Tablet

Bacterial infections

Directions for Use

Tablet: Take it as advised by your doctor. Swallow it as a whole with water; do not crush, break or chew it.Syrup: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack. The dose and duration can vary depending on your condition and the severity of the infection.

Medicinal Benefits

CO-Trimoxazole DS Tablet belongs to the group of medicines called ‘antibiotics’ used to treat various bacterial infections of the urinary tract, respiratory tract (bronchitis), ear (otitis media), lungs (pneumonia), skin, brain, and toxoplasmosis (infection caused by a bacteria called toxoplasma). CO-Trimoxazole DS Tablet contains Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. Tetrahydrofolic acid and dihydrofolic acid are essential for the formation of proteins and nucleic acids, which are necessary for the survival of bacteria. By inhibiting these, CO-Trimoxazole DS Tablet kills the bacteria and stops their growth. Thereby, it helps to treat bacterial infections. CO-Trimoxazole DS Tablet is a broad-spectrum antibiotic that is active against a wide range of gram-positive and gram-negative bacteria such as Streptococcus pneumonia, Escherichia coli, Klebsiella species, Enterobacter species, Haemophilus influenzae, etc.

Storage

Keep CO-Trimoxazole DS Tablet out of the sight and reach of children.

Side effects of CO-Trimoxazole DS Tablet

Hives Or Skin Rash

Avoid trigger foods that can cause allergic reactions, such as nuts, shellfish, or dairy products.
Keep a food diary to track potential food allergens.
Include omega-3 rich foods like salmon and walnuts to reduce inflammation.
Wear loose, comfortable clothing made from soft fabrics like cotton.
Apply cool compresses or take cool baths to reduce itching.
Use gentle soaps and avoid harsh skin products.
Reduce stress through relaxation techniques like meditation or deep breathing.

Rash

Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
Protect your skin from extreme heat and try to apply wet compresses.
Soak in the cool bath, which gives a soothing impact to the affected area.

Vomiting

To prevent, manage, and treat Constipation caused by medication usage, follow these steps:

Preventing Vomiting (Before it Happens)
Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
Having a small meal before taking your medication can help reduce nausea and vomiting.
Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
Managing Vomiting (If it Happens)
Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
What to Do if Vomiting Persists
Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Drug Warnings

Do not take CO-Trimoxazole DS Tablet if you are allergic to any of its contents if you have severe liver or kidney problems, thrombocytopenia (low levels of platelets in the blood), or porphyria (rare blood problem that affects the skin or nervous system). Do not take CO-Trimoxazole DS Tablet on your own, as self-medication may lead to antibiotic resistance in which antibiotics fail to act against specific bacterial infections. Consult your doctor immediately if you experience skin rash or prolonged, significant diarrhoea with abdominal pains. Talk to your doctor before taking CO-Trimoxazole DS Tablet if you have severe allergies, asthma, ulcers, blood disorders, thyroid dysfunction, diabetes, are elderly, underweight, or malnourished if you have a folic acid deficiency, glucose-6-phosphate dehydrogenase deficiency, or high levels of potassium in the blood. Avoid taking CO-Trimoxazole DS Tablet if you are pregnant or breastfeeding unless prescribed by a doctor. Avoid alcohol consumption while taking CO-Trimoxazole DS Tablet to prevent unpleasant side-effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, and vomiting. CO-Trimoxazole DS Tablet will not treat a viral infection. Drink plenty of fluids to prevent kidney stones while taking CO-Trimoxazole DS Tablet .

Drug-Drug Interactions

TrimethoprimBCG vaccine

Critical

TrimethoprimLosartan

Severe

Drug-Drug Interactions

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TrimethoprimBCG vaccine

Critical

How does the drug interact with CO-Trimoxazole DS Tablet:
Taking CO-Trimoxazole DS Tablet with BCG vaccine can reduce the effectiveness of the BCG vaccine

How to manage the interaction:
Although there is an interaction between CO-Trimoxazole DS Tablet and BCG vaccine is not recommended, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.

TrimethoprimLosartan

Severe

How does the drug interact with CO-Trimoxazole DS Tablet:
Coadministration of Losartan with CO-Trimoxazole DS Tablet can increase potassium levels which can lead to severe conditions like kidney problems.

How to manage the interaction:
Taking Losartan with CO-Trimoxazole DS Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.

TrimethoprimLevobupivacaine

Severe

How does the drug interact with CO-Trimoxazole DS Tablet:
Taking CO-Trimoxazole DS Tablet with Levobupivacaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although there is a possible interaction between Levobupivacaine and CO-Trimoxazole DS Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience nausea, headache, dizziness, fatigue, or difficulty breathing, it's best to contact your doctor right away. Do not stop using any medications without talking to your doctor.

TrimethoprimPotassium citrate

Severe

How does the drug interact with CO-Trimoxazole DS Tablet:
Taking Potassium citrate with CO-Trimoxazole DS Tablet may increase potassium levels in the blood, which can lead to kidney failure, muscular paralysis, and abnormal heart rhythm.

How to manage the interaction:
Although there is a possible interaction between CO-Trimoxazole DS Tablet and Potassium citrate, you can take these medicines together if prescribed by your doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.

TrimethoprimIrbesartan

Severe

How does the drug interact with CO-Trimoxazole DS Tablet:
Taking Irbesartan with CO-Trimoxazole DS Tablet may increase potassium levels in the blood and kidney problems.

How to manage the interaction:
Although taking Irbesartan with CO-Trimoxazole DS Tablet together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, consult your doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, or a slow or irregular heartbeat. Do not discontinue any medications without a doctor's advice.

TrimethoprimOlmesartan medoxomil

Severe

How does the drug interact with CO-Trimoxazole DS Tablet:
Taking olmesartan medoxomil with CO-Trimoxazole DS Tablet may increase potassium levels in the blood.

How to manage the interaction:
Although taking olmesartan medoxomil with CO-Trimoxazole DS Tablet may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.

TrimethoprimTelmisartan

Severe

How does the drug interact with CO-Trimoxazole DS Tablet:
Taking CO-Trimoxazole DS Tablet with telmisartan may increase potassium levels in the blood.

How to manage the interaction:
Although there is an interaction between telmisartan and CO-Trimoxazole DS Tablet, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, and a weak pulse. Do not discontinue the medications without consulting a doctor.

TrimethoprimBupivacaine

Severe

How does the drug interact with CO-Trimoxazole DS Tablet:
Taking Bupivacaine and CO-Trimoxazole DS Tablet may cause methemoglobinemia, (blood disorder that affects how red blood cells deliver oxygen throughout the body).

How to manage the interaction:
Although there is an interaction between bupivacaine and CO-Trimoxazole DS Tablet, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience nausea, headache, dizziness, lightheadedness, fatigue, or shortness of breath. Do not discontinue any medications without consulting a doctor.

TrimethoprimMethotrexate

Severe

How does the drug interact with CO-Trimoxazole DS Tablet:
Coadministration of CO-Trimoxazole DS Tablet with methotrexate can increase the risk or severity of blood disorders.

How to manage the interaction:
Although there is a possible interaction between CO-Trimoxazole DS Tablet and methotrexate, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as pale skin, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not stop using any medications without consulting to a doctor.

TrimethoprimFolic acid

Severe

How does the drug interact with CO-Trimoxazole DS Tablet:
CO-Trimoxazole DS Tablet may decrease the blood levels and effects of folic acid.

How to manage the interaction:
Although there is a possible interaction between Folic acid and CO-Trimoxazole DS Tablet, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without consulting your doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Antibiotics can alter the useful bacteria in the stomach, which helps in digestion. Therefore, you are advised to take foods rich in probiotics, such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk natto, and cheese.
Eat fiber-rich food like whole grains, beans, lentils, berries, broccoli, peas, and bananas.
Avoid foods rich in calcium, grapefruit, and grapefruit juice, as they might hinder antibiotic absorption.
Avoid the consumption of alcohol to treat your condition effectively.
Avoid the usage of tobacco.
To cure your condition, effectually complete the full course of CO-Trimoxazole DS Tablet even though you find symptomatic relief.

Side Effects of CO-Trimoxazole DS Tablet

Mouth ulcers
Headache
Mouth ulcers
Diarrhea
Blood or cloudiness in your urine
Depression
Tingling or numbness in your hands and feet
Hallucinations

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

CO-Trimoxazole DS Tablet Substitute

Cotrimoxazole DS Tablet 10's

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₹3.24per tablet

Co-Trimoxazole Double Strength Tablet 10's

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Viktrim DS Tablet 10's

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does CO-Trimoxazole DS Tablet work?

CO-Trimoxazole DS Tablet contains Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. Tetrahydrofolic acid and dihydrofolic acid are essential for the formation of proteins and nucleic acids, which are necessary for the survival of bacteria. By inhibiting these, CO-Trimoxazole DS Tablet kills the bacteria and stops their growth. Thus, helps to treat bacterial infections.

Does CO-Trimoxazole DS Tablet cause thrush?

CO-Trimoxazole DS Tablet causes thrush or candidiasis, a fungal infection occurring due to the overgrowth of yeast-like fungus in the mouth or throat. Regularly rinse your mouth with water to prevent the growth of fungus.

Does CO-Trimoxazole DS Tablet cause diarrhoea?

Diarrhoea might be a side-effect of CO-Trimoxazole DS Tablet . Drink lots of fluids and eat food rich in fibre if you experience diarrhoea. If you find blood in your stools (tarry stools) or if you experience prolonged diarrhoea with abdominal pain, stop taking CO-Trimoxazole DS Tablet and consult your doctor. Do not take anti-diarrheal medicine on your own.

Can I stop taking CO-Trimoxazole DS Tablet on my own?

It is recommended to complete the course of CO-Trimoxazole DS Tablet even if you feel better as it is an antibiotic, and leaving it in between may lead to recurring infections. Continue taking CO-Trimoxazole DS Tablet for as long as your doctor has prescribed to treat your condition effectually.

Does CO-Trimoxazole DS Tablet affect diagnostic test results?

CO-Trimoxazole DS Tablet may affect certain laboratory test results. Inform the person doing the tests that you are taking CO-Trimoxazole DS Tablet .

Does CO-Trimoxazole DS Tablet cause abnormal heartbeats?

CO-Trimoxazole DS Tablet may cause high levels of potassium in the blood, leading to abnormal heartbeats (palpitations). Regular potassium levels and heart rate monitoring is recommended while taking CO-Trimoxazole DS Tablet .

Drug-Drug Interactions Checker List

AMANTADINE
CYCLOSPORINE
INDOMETHACIN
LEUCOVORIN
METHOTREXATE
PYRIMETHAMINE
BENAZEPRIL
QUINAPRIL
ENALAPRIL
LISINOPRIL
RAMIPRIL
CHLORTHALIDONE
HYDROCHLOROTHIAZIDE
WARFARIN

Special Advise

CO-Trimoxazole DS Tablet may affect certain laboratory test results, such as blood tests. Inform the person doing the tests that you are taking CO-Trimoxazole DS Tablet . Your doctor may advise you to get regular tests if you have kidney problems or if you have been prescribed CO-Trimoxazole DS Tablet for a longer duration to know if the medicine is working properly.

Disease/Condition Glossary

Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect our body. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. It can target any body part and multiply very quickly. When you get infected with bacteria, you can experience generalized symptoms like fevers, chills, and fatigue. Bacteria are of various forms comprising, commonly spherical, rod, and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. Anyone can become infected with a bacterial infection. But, people with weak immune systems or taking immunosuppressive medicine are more prone to bacterial infection.