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Reviewed By Sureshvarma D , MPharma
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Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Cotrimoxazole DS Tablet 10's

Cotrimoxazole DS Tablet 10's belongs to the group of medicines called antibiotics used to treat and prevent lung infections caused by a bacteria called Pneumocystis jirovecii, infections caused by a bacteria called Toxoplasma, urinary tract infections (water infections), respiratory tract infections such as bronchitis, ear infections such as otitis media. Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. Cotrimoxazole DS Tablet 10's does not work against infections caused by the virus, including cold and flu.

Cotrimoxazole DS Tablet 10's contains Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. Tetrahydrofolic acid and dihydrofolic acid are essential for the formation of proteins and nucleic acids, which are necessary for the survival of bacteria. By inhibiting these, Cotrimoxazole DS Tablet 10's kills the bacteria and stops their growth. Thereby, it helps to treat bacterial infections.

Take Cotrimoxazole DS Tablet 10's as prescribed by your doctor. The dose and duration of Cotrimoxazole DS Tablet 10's can vary depending on your condition and the severity of the infection. In some cases, you may experience certain common side effects such as headache, diarrhoea, skin rashes, nausea, vomiting, heart problems, fever, convulsions or seizures, blood or cloudiness in your urine, hallucinations, and mouth ulcers. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before starting Cotrimoxazole DS Tablet 10's, please inform your doctor if you have any allergy (against any antibiotic), or kidney or liver problems. Do not take Cotrimoxazole DS Tablet 10's on your own as self-medication may lead to antibiotic resistance in which antibiotics fail to act against specific bacterial infections. Consult your doctor before taking Cotrimoxazole DS Tablet 10's if you are pregnant or breastfeeding. Avoid alcohol consumption to prevent unpleasant side effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, and vomiting. Cotrimoxazole DS Tablet 10's should not be given to children below 12 years. Keep your doctor informed about all the medicines you are taking and your health condition to rule out any unpleasant side effects. Also, it is recommended to complete the course of medicine even if you feel better, as it is an antibiotic. Leaving it in between may lead to even severe infection that will, in fact, stop responding to the antibiotic (antibiotic resistance).

Uses of Cotrimoxazole DS Tablet 10's

Bacterial infections

Directions for Use

Tablet: Take it as advised by your doctor. Swallow it as a whole with water; do not crush, break or chew it.Syrup: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack. The dose and duration can vary depending on your condition and the severity of the infection.

Medicinal Benefits

Cotrimoxazole DS Tablet 10's belongs to the group of medicines called ‘antibiotics’ used to treat various bacterial infections of the urinary tract, respiratory tract (bronchitis), ear (otitis media), lungs (pneumonia), skin, brain, and toxoplasmosis (infection caused by a bacteria called toxoplasma). Cotrimoxazole DS Tablet 10's contains Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. Tetrahydrofolic acid and dihydrofolic acid are essential for the formation of proteins and nucleic acids, which are necessary for the survival of bacteria. By inhibiting these, Cotrimoxazole DS Tablet 10's kills the bacteria and stops their growth. Thereby, it helps to treat bacterial infections. Cotrimoxazole DS Tablet 10's is a broad-spectrum antibiotic that is active against a wide range of gram-positive and gram-negative bacteria such as Streptococcus pneumonia, Escherichia coli, Klebsiella species, Enterobacter species, Haemophilus influenzae, etc.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Cotrimoxazole DS Tablet 10's

  • Mouth ulcers
  • Headache
  • Mouth ulcers
  • Diarrhea
  • Blood or cloudiness in your urine
  • Depression
  • Tingling or numbness in your hands and feet
  • Hallucinations

Drug Warnings

Do not take Cotrimoxazole DS Tablet 10's if you are allergic to any of its contents if you have severe liver or kidney problems, thrombocytopenia (low levels of platelets in the blood), or porphyria (rare blood problem that affects the skin or nervous system). Do not take Cotrimoxazole DS Tablet 10's on your own, as self-medication may lead to antibiotic resistance in which antibiotics fail to act against specific bacterial infections. Consult your doctor immediately if you experience skin rash or prolonged, significant diarrhoea with abdominal pains. Talk to your doctor before taking Cotrimoxazole DS Tablet 10's if you have severe allergies, asthma, ulcers, blood disorders, thyroid dysfunction, diabetes, are elderly, underweight, or malnourished if you have a folic acid deficiency, glucose-6-phosphate dehydrogenase deficiency, or high levels of potassium in the blood. Avoid taking Cotrimoxazole DS Tablet 10's if you are pregnant or breastfeeding unless prescribed by a doctor. Avoid alcohol consumption while taking Cotrimoxazole DS Tablet 10's to prevent unpleasant side-effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, and vomiting. Cotrimoxazole DS Tablet 10's will not treat a viral infection. Drink plenty of fluids to prevent kidney stones while taking Cotrimoxazole DS Tablet 10's.

Drug-Drug Interactions

verifiedApollotooltip
TrimethoprimBCG vaccine
Critical
TrimethoprimCalcium folinate
Severe

Drug-Drug Interactions

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TrimethoprimBCG vaccine
Critical
How does the drug interact with Cotrimoxazole DS Tablet:
Taking Cotrimoxazole DS Tablet with BCG vaccine can reduce the effectiveness of the BCG vaccine

How to manage the interaction:
Although there is an interaction between Cotrimoxazole DS Tablet and BCG vaccine is not recommended, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
TrimethoprimCalcium folinate
Severe
How does the drug interact with Cotrimoxazole DS Tablet:
Co-administration of Calcium folinate with Cotrimoxazole DS Tablet may increase rates of treatment failure.

How to manage the interaction:
Although there is an interaction between calcium folinate and Cotrimoxazole DS Tablet, but it can be taken together if prescribed by the doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to your doctor.
TrimethoprimTetracaine
Severe
How does the drug interact with Cotrimoxazole DS Tablet:
Co-administration of Cotrimoxazole DS Tablet with tetracaine can result in blood disorders.

How to manage the interaction:
Although there is an interaction between Cotrimoxazole DS Tablet and tetracaine, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience nausea, headache, dizziness, lightheadedness, fatigue, or shortness of breath. Do not discontinue any medications without consulting a doctor.
TrimethoprimCandesartan
Severe
How does the drug interact with Cotrimoxazole DS Tablet:
Taking Cotrimoxazole DS Tablet with candesartan can increase the risk of hyperkalemia (high potassium levels in the blood) and kidney problems.

How to manage the interaction:
Although there is an interaction between candesartan and Cotrimoxazole DS Tablet, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
TrimethoprimOlmesartan medoxomil
Severe
How does the drug interact with Cotrimoxazole DS Tablet:
Taking olmesartan medoxomil with Cotrimoxazole DS Tablet may increase potassium levels in the blood.

How to manage the interaction:
Although taking olmesartan medoxomil with Cotrimoxazole DS Tablet may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
TrimethoprimRopivacaine
Severe
How does the drug interact with Cotrimoxazole DS Tablet:
Taking Ropivacaine with Cotrimoxazole DS Tablet may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although there is an interaction between ropivacaine and Cotrimoxazole DS Tablet, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath. Do not stop using any medications without a doctor's advice.
TrimethoprimValsartan
Severe
How does the drug interact with Cotrimoxazole DS Tablet:
Using Cotrimoxazole DS Tablet together with valsartan may increase potassium levels in the blood.

How to manage the interaction:
Although taking Cotrimoxazole DS Tablet together with Valsartan may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Do not discontinue any medication without consulting a doctor.
TrimethoprimProcaine
Severe
How does the drug interact with Cotrimoxazole DS Tablet:
Co-administration of Cotrimoxazole DS Tablet with procaine may increase the risk of blood disorders.

How to manage the interaction:
Taking Cotrimoxazole DS Tablet with Procaine together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms like gray skin, feeling sick, headache, dizziness, tiredness, trouble breathing, fast heartbeat, or feeling anxious or confused, contact your doctor right away. Do not stop using any medications without talking to your doctor.
TrimethoprimLosartan
Severe
How does the drug interact with Cotrimoxazole DS Tablet:
Coadministration of Losartan with Cotrimoxazole DS Tablet can increase potassium levels which can lead to severe conditions like kidney problems.

How to manage the interaction:
Taking Losartan with Cotrimoxazole DS Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
TrimethoprimAzilsartan medoxomil
Severe
How does the drug interact with Cotrimoxazole DS Tablet:
Coadministration of Azilsartan medoxomil with Cotrimoxazole DS Tablet may increase potassium levels in the blood.

How to manage the interaction:
Although there is an interaction between azilsartan medoxomil and Cotrimoxazole DS Tablet, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience vomiting, weakness, or tingling in your hands and feet. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach, which helps in digestion. Therefore, you are advised to take foods rich in probiotics, such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk natto, and cheese.
  • Eat fiber-rich food like whole grains, beans, lentils, berries, broccoli, peas, and bananas.
  • Avoid foods rich in calcium, grapefruit, and grapefruit juice, as they might hinder antibiotic absorption.
  • Avoid the consumption of alcohol to treat your condition effectively.
  • Avoid the usage of tobacco.
  • To cure your condition, effectually complete the full course of Cotrimoxazole DS Tablet 10's even though you find symptomatic relief.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Cotrimoxazole DS Tablet 10's Substitute

Substitutes safety advice
  • Viktrim DS Tablet 10's

    by Others

    2.70per tablet
  • Co-Trimoxazole Double Strength Tablet 10's

    by Others

    1.28per tablet
  • CO-Trimoxazole DS Tablet 16's

    by Others

    3.15per tablet

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • AMANTADINE
  • CYCLOSPORINE
  • INDOMETHACIN
  • LEUCOVORIN
  • METHOTREXATE
  • PYRIMETHAMINE
  • BENAZEPRIL
  • QUINAPRIL
  • ENALAPRIL
  • LISINOPRIL
  • RAMIPRIL
  • CHLORTHALIDONE
  • HYDROCHLOROTHIAZIDE
  • WARFARIN

Special Advise

  • Cotrimoxazole DS Tablet 10's may affect certain laboratory test results, such as blood tests. Inform the person doing the tests that you are taking Cotrimoxazole DS Tablet 10's. Your doctor may advise you to get regular tests if you have kidney problems or if you have been prescribed Cotrimoxazole DS Tablet 10's for a longer duration to know if the medicine is working properly.

Disease/Condition Glossary

Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect our body. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. It can target any body part and multiply very quickly. When you get infected with bacteria, you can experience generalized symptoms like fevers, chills, and fatigue. Bacteria are of various forms comprising, commonly spherical, rod, and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. Anyone can become infected with a bacterial infection. But, people with weak immune systems or taking immunosuppressive medicine are more prone to bacterial infection.

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