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Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
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Manufacturer/Marketer :

Zydus Healthcare Ltd

Consume Type :

NASAL

Return Policy :

Not Returnable

Expires on or after :

About Combinase FT Nasal Spray

Combinase FT Nasal Spray belongs to the class of medications called 'anti-allergic' primarily used to treat allergic symptoms like sneezing, runny nose, congestion, stuffy nose, or watery eyes. An allergy is a condition that occurs when the immune system reacts to a foreign substance that is typically not harmful to your body. These foreign substances are known as ‘allergens.’ Allergic condition varies from person to person. Some might be allergic to certain foods and seasonal allergies like hay fever, pollen, or pet dander. One of the main symptoms of allergy is cough, and it acts as a reflex action in the throat when there is any mucus or foreign irritant entry into the respiratory system.

Combinase FT Nasal Spray is a combination of two drugs, namely: Fluticasone propionate (corticosteroid) and Azelastine (antihistamine/antiallergic). Fluticasone propionate belongs to the class of corticosteroids that works by acting inside cells of the nasal lining and stops the release of certain chemicals in the body that cause inflammatory reactions thereby relieving sneezing, runny or blocked nose, and sinus discomfort. On the other hand, Azelastine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.  It helps to provide relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness.

Use Combinase FT Nasal Spray as prescribed. Your doctor will recommend how often you take Combinase FT Nasal Spray based on your medical condition. Some people may experience headache, taste changes, or nose bleeds. Most of these side effects of Combinase FT Nasal Spray do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Combinase FT Nasal Spray or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Combinase FT Nasal Spray . Combinase FT Nasal Spray is not recommended for children below 6 years of age. If you experience any changes in vision, tiredness, nausea, vomiting, light-headedness, chills, fever, body pains, sores, redness or white patches in the mouth or throat, runny nose, severe nosebleeds, or increased drowsiness, stop taking Combinase FT Nasal Spray and consult a doctor immediately. Avoid contact with people who have infections or who are sick as Combinase FT Nasal Spray may weaken the immune system causing infections easily. If you have chickenpox, measles, tuberculosis, surgery or injury on the nose, glaucoma, cataracts, herpes infection of the eyes, ulcers or sores inside the nose, inform your doctor before taking Combinase FT Nasal Spray .

Uses of Combinase FT Nasal Spray

Allergic symptoms

Directions for Use

Use Combinase FT Nasal Spray as prescribed by your doctor. Check the label for directions before using Combinase FT Nasal Spray . Insert the tip of the bottle into a nostril while closing the other nostril and spray Combinase FT Nasal Spray towards the sides of the nostril. Keep your head straight and breathe gently. Repeat the same process for another nostril.

Medicinal Benefits

Combinase FT Nasal Spray is a combination of two drugs, namely: Fluticasone propionate and Azelastine used to treat allergic symptoms such as sneezing, runny nose, congestion, stuffy nose, or watery eyes. Fluticasone propionate belongs to the class of corticosteroids that works by acting inside cells of the nasal lining. It stops the release of certain chemicals in the body that cause inflammatory reactions, thereby providing relief from sneezing, runny or blocked nose, and sinus discomfort. Azelastine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.  It helps to provide relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness. Together Combinase FT Nasal Spray relieves allergic symptoms, including seasonal allergies, and reduces inflammation of nasal passage.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to Combinase FT Nasal Spray or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Combinase FT Nasal Spray . Combinase FT Nasal Spray is not recommended for children below 6 years of age. If you experience any changes in vision, tiredness, nausea, vomiting, light-headedness, chills, fever, body pains, sores, redness or white patches in the mouth or throat, runny nose, severe nosebleeds, or increased drowsiness, stop taking Combinase FT Nasal Spray and consult a doctor immediately. Avoid contact with people who have infections or who are sick as Combinase FT Nasal Spray may weaken the immune system causing infections easily. If you have chickenpox, measles, tuberculosis, surgery or injury on the nose, glaucoma, cataracts, herpes infection of the eyes, ulcers or sores inside the nose, inform your doctor before taking Combinase FT Nasal Spray .

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Combinase FT Nasal Spray 9.8 gm:
Using Combinase FT Nasal Spray 9.8 gm with Mifepristone can reduce the effect of Combinase FT Nasal Spray 9.8 gm.

How to manage the interaction:
Taking Combinase FT Nasal Spray 9.8 gm with Mifepristone is not recommended, but it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Combinase FT Nasal Spray 9.8 gm:
Co-administration of desmopressin together with fluticasone may increase the risk of hyponatremia, a condition associated with low levels of salt in the blood.

How to manage the interaction:
If you have to use Desmopressin and Fluticasone together, your doctor may adjust the dose or monitor you more frequently to safely use both medications. However, if you experience loss of appetite, headache, nausea, vomiting, lethargy (very tired), irritability, difficulty concentrating, weakness, unsteadiness, memory impairment, confusion, muscle spasm, decreased urination, and/or sudden weight gain, contact your doctor immediately as these may be symptoms of water intoxication (water poisoning) and hyponatremia (low levels of salt in the blood). Do not discontinue the medication without consulting a doctor.
Fluticasone furoateFosamprenavir
Severe
How does the drug interact with Combinase FT Nasal Spray 9.8 gm:
When Combinase FT Nasal Spray 9.8 gm is taken with fosamprenavir, the amount of Combinase FT Nasal Spray 9.8 gm in the blood may increase.

How to manage the interaction:
Although taking Combinase FT Nasal Spray 9.8 gm and Dinutuximab together can evidently cause an interaction, can be taken together if advised by a doctor. However, if you experience weight gain, swelling, high blood sugar, muscle weakness, acne, depression, thinning skin, easy bruising, stretch marks, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Combinase FT Nasal Spray 9.8 gm:
Taking Combinase FT Nasal Spray 9.8 gm with Voriconazole may increase the absorption of Combinase FT Nasal Spray 9.8 gm into the bloodstream and increase the risk of side effects.

How to manage the interaction:
Although Combinase FT Nasal Spray 9.8 gm and Voriconazole can cause an interaction, but can be taken together if advised by a doctor. However, if you experience swelling, muscle weakness, excessive growth of facial or body hair contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Combinase FT Nasal Spray 9.8 gm:
The blood levels of Combinase FT Nasal Spray 9.8 gm can be increased when it is combined with Boceprevir.

How to manage the interaction:
Co-administration of Combinase FT Nasal Spray 9.8 gm with Boceprevir can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience swelling, weight gain, high blood sugar, weak muscles, feeling down, acne, thin skin, easy bruising, irregular periods, too much facial or body hair, bruises, infections, or asthma attacks contact your doctor right away. Do not discontinue any medications without consulting your doctor.
Severe
How does the drug interact with Combinase FT Nasal Spray 9.8 gm:
When Combinase FT Nasal Spray 9.8 gm is taken with Nefazodone, the amount of Combinase FT Nasal Spray 9.8 gm in the blood can go up.

How to manage the interaction:
Co-administration of Combinase FT Nasal Spray 9.8 gm with Nefazodone can possibly result in an interaction, but can be taken together if advised by a doctor. However, if you experience weight gain, high blood pressure, swelling, high blood sugar, muscle weakness, acne, depression, thinning skin, easy bruising, stretch marks, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Combinase FT Nasal Spray 9.8 gm:
When Combinase FT Nasal Spray 9.8 gm is taken with delavirdine, the amount of Combinase FT Nasal Spray 9.8 gm in the blood may increase.

How to manage the interaction:
Co-administration of Combinase FT Nasal Spray 9.8 gm with Delavirdine can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these signs - swelling, weight gain, high blood sugar, weak muscles, acne, thin skin, easy bruising, irregular periods, too much facial or body hair, bruises, infections, or asthma attacks - contact your doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Combinase FT Nasal Spray 9.8 gm:
Taking Clarithromycin with Combinase FT Nasal Spray 9.8 gm may increase the absorption of Combinase FT Nasal Spray 9.8 gm in the blood.

How to manage the interaction:
Although there is a possible interaction, Clarithromycin can be taken with Combinase FT Nasal Spray 9.8 gm if prescribed by the doctor. Consult the prescriber if you experience side effects such as swelling, weight gain, high blood glucose, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist. Do not discontinue the medication without consulting a doctor.
Severe
How does the drug interact with Combinase FT Nasal Spray 9.8 gm:
When Combinase FT Nasal Spray 9.8 gm is taken with Idelalisib, the amount of Combinase FT Nasal Spray 9.8 gm in the blood can go up.

How to manage the interaction:
Although there is a possible interaction between Combinase FT Nasal Spray 9.8 gm and Idelalisib, but can be taken together if advised by a doctor. However, if you experience weight gain, high blood pressure, swelling, high blood sugar, muscle weakness, acne, depression, thinning skin, easy bruising, stretch marks, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Combinase FT Nasal Spray 9.8 gm:
Combining Cladribine with Combinase FT Nasal Spray 9.8 gm can increase the risk of negative side effects.

How to manage the interaction:
Although taking Combinase FT Nasal Spray 9.8 gm and Cladribine together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms - infection, fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain or burning while peeing - make sure to contact your doctor right away. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Add ginger to foods or tea as it contains some anti-inflammatory compounds that can relax membranes in the airways and reduce cough, irritation and swelling in nasal passages.
  • Staying hydrated is vital for those with a cough or cold. Drink liquids at room temperature to get relief from a runny nose, cough, and sneezing.
  • The immune system is affected by stress and raises the risk of being sick. Do meditation, deep breathing, regular exercise and try progressive muscle relaxation techniques to get relief from stress.
  • It is advised to avoid contact with known allergens (allergy-causing agents) such as pollen, dust, etc. Certain food items are known to cause allergies to you.
  • Maintain personal hygiene and keep your surroundings clean.

Habit Forming

No

Therapeutic Class

ANTIALLERGIC

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Combinase FT Nasal Spray contains Fluticasone propionate and Azelastine. Fluticasone propionate is a corticosteroid that works by acting inside cells of the nasal lining and stops the release of certain chemicals in the body that cause inflammatory reactions. Thereby, provides relief from sneezing, runny or blocked nose and sinus discomfort. Azelastine is an antihistamine (anti-allergic drug) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps to provide relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness.

You are recommended to avoid taking grapefruit juice with Combinase FT Nasal Spray as they may lead to adrenal insufficiency and Cushing’s syndrome.

No, you are not recommended to consume alcohol with Combinase FT Nasal Spray as it may cause increased drowsiness, dizziness, impairment of judgement and thinking. However, please consult a doctor before consuming alcohol with Combinase FT Nasal Spray .

Combinase FT Nasal Spray is not recommended for children below 6 years as the safety and effectiveness were not established. However, please consult a doctor before using Combinase FT Nasal Spray in children.

Yes, Combinase FT Nasal Spray may cause drowsiness in some people, especially in people consuming alcohol with Combinase FT Nasal Spray . It is not necessary for everyone taking Combinase FT Nasal Spray to experience this side effect. Therefore, avoid driving if you feel drowsy after taking Combinase FT Nasal Spray .

You are not recommended to take more than the prescribed dose of Combinase FT Nasal Spray or for a prolonged time as it may cause adverse effects such as changes in body fat (especially in the back, waist, neck and face), easy bruising, skin thinning, increased facial hair or acne, loss of interest in sex, impotence or menstrual problems. However, if you experience any of these symptoms while taking Combinase FT Nasal Spray , please consult a doctor immediately.

No, Combinase FT Nasal Spray is not used to treat asthma attacks. Combinase FT Nasal Spray is used to prevent allergic symptoms that can cause asthma. Therefore, it is recommended to carry a rescue inhaler always to treat asthma attacks.

No, you are not recommended to stop taking Combinase FT Nasal Spray without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Combinase FT Nasal Spray for as long as your doctor has prescribed it, and if you experience any difficulty while taking Combinase FT Nasal Spray , please consult your doctor.

You should avoid taking Combinase FT Nasal Spray and consult a doctor before using Combinase FT Nasal Spray if you have had any recent nose problems (like nose bleed, nose injury, nose ulcers, or nose surgery), infections like tuberculosis (TB), eye problems like herpes eye infection, glaucoma, or cataracts.

Drug-Drug Interactions Checker List

  • DULOXETINE
  • ESCITALOPRAM
  • PREGABALIN
  • RITONAVIR
  • KETOCONAZOLE
  • FLUCONAZOLE
  • ITRACONAZOLE
  • CETIRIZINE

Special Advise

Certain blood tests are recommended while taking Combinase FT Nasal Spray to monitor serum cortisol levels as Combinase FT Nasal Spray may increase these levels.

Disease/Condition Glossary

Allergy: It is a condition that occurs when the immune system reacts to a foreign substance that is typically not harmful to your body. These foreign substances are known as ‘allergens.’ Allergic condition varies from person to person. Some might be allergic to certain foods and seasonal allergies like hay fever, pollen, or pet dander. One of the main symptoms of allergy is cough, and it acts as a reflex action in the throat when there is any mucus or foreign irritant entry into the respiratory system.

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