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Written By Sureshvarma D , MPharma
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Whats That

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Synonym

MESALAZINE

Composition

MESALAMINE-1.2GM

Manufacturer/Marketer

Tas Med India Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Cosala OD Tablet

Cosala OD Tablet belongs to a class of drugs called 'anti-inflammatory drugs used to treat ulcerative colitis and Crohn’s disease. Ulcerative colitis is a type of chronic inflammatory bowel disease that causes inflammation of the large intestine lining (colon). It produces ulcers on the colon's lining, which may cause bleeding and discharge of pus and mucus.

Cosala OD Tablet contains Mesalamine, which works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thereby, it reduces inflammation (swelling) in the intestines and provides relief from symptoms such as stomach pain or bleeding.

Take Cosala OD Tablet as prescribed. You are advised to use Cosala OD Tablet for as long as your doctor has recommended it for you based on your medical condition. In some cases, you may experience diarrhoea, stomach pain, headache, nausea, vomiting or flatulence (gas). Most of these side effects of Cosala OD Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Inform your doctor if you are allergic to any components present in Cosala OD Tablet . Cosala OD Tablet should be used with caution in the elderly. If you are pregnant or breastfeeding, please inform your doctor before taking Cosala OD Tablet . Mesalamine tablet is not recommended for children below two years, and granules are not recommended for children below six years. However, Cosala OD Tablet should be given to children only if advised by a doctor. Avoid taking Cosala OD Tablet if you have severe kidney failure. If you have stomach pain, cramps, severe headache, fever or rash, stop taking Cosala OD Tablet immediately and consult a doctor.

Uses of Cosala OD Tablet

Ulcerative colitis, Crohn’s disease

Directions for Use

Tablet: Take it as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.Granules: Empty the contents directly on the tongue and drink some water or orange juice. They can also be mixed with yoghurt and should be taken immediately without chewing on granules.Pellets: Check the label for directions before use and take it as advised by the doctor.

Medicinal Benefits

Cosala OD Tablet contains Mesalamine, an anti-inflammatory drug used to treat ulcerative colitis and Crohn’s disease. It works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thereby helping reduce inflammation (redness and swelling) in the intestines and providing relief from symptoms such as stomach pain or bleeding. Also, Cosala OD Tablet may prevent further episodes of ulcerative colitis.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Cosala OD Tablet

  • Diarrhoea
  • Stomach pain
  • Headache
  • Nausea
  • Vomiting
  • Flatulence (gas)

Drug Warnings

Inform your doctor if you're allergic to any ingredient in the Cosala OD Tablet . Cosala OD Tablet should be used with caution in the elderly. If you are pregnant or breastfeeding, inform your doctor before taking Cosala OD Tablet . Avoid taking Cosala OD Tablet if you have severe kidney failure. Severe skin reactions such as toxic epidermal necrolysis (skin peeling and blistering) or Stevens-Johnson syndrome (a painful rash that spreads and blisters) can occur in some patients taking Cosala OD Tablet . Therefore, if you notice any skin reactions while taking Cosala OD Tablet , please consult a doctor immediately. If you have stomach pain, cramps, severe headache, fever or rash, stop taking Cosala OD Tablet immediately and consult a doctor. Avoid taking Cosala OD Tablet if you have had blood abnormalities or kidney problems while taking other medicines such as Sulphasalazine.

Drug-Drug Interactions

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MesalazineCidofovir
Critical
MesalazineDeferasirox
Severe

Drug-Drug Interactions

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MesalazineCidofovir
Critical
How does the drug interact with Cosala OD Tablet:
Co-administration of Cosala OD Tablet with Cidofovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Cosala OD Tablet with Cidofovir is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience increased or decreased urination, sudden weight gain or loss, shortness of breath, consult a doctor. Do not discontinue any medications without consulting a doctor.
MesalazineDeferasirox
Severe
How does the drug interact with Cosala OD Tablet:
Co-administration of Deferasirox with Cosala OD Tablet may increase the risk of kidney problems.

How to manage the interaction:
Although there is a possibility of interaction between Cosala OD Tablet and Deferasirox but they can be taken together if a doctor has prescribed them. Consult a doctor immediately if you experience any symptoms such as increased or decreased urination, abrupt weight gain or loss, weakness, or dizziness. Do not discontinue the medication without consulting a doctor.
MesalazineMetrizamide
Severe
How does the drug interact with Cosala OD Tablet:
Co-administration of Metrizamide with Cosala OD Tablet may increase the risk of kidney problems.

How to manage the interaction:
Although, there is a possibility of interaction between Cosala OD Tablet with Metrizamide they can be taken together if a doctor has prescribed them. Consult a doctor immediately if you experience any symptoms such as swelling in feet and ankles, dry, itchy skin, urinating either too much or too little. Do not discontinue any medication without consulting a doctor.
MesalazineRanitidine
Severe
How does the drug interact with Cosala OD Tablet:
Co-administration of Ranitidine with Cosala OD Tablet can decrease the levels of Cosala OD Tablet, which may be less effective in treating a condition.

How to manage the interaction:
There may be a possible interaction between Cosala OD Tablet with Ranitidine, but they can be taken together if a doctor has prescribed them. Do not discontinue any medications without consulting a doctor.
MesalazineTenofovir alafenamide
Severe
How does the drug interact with Cosala OD Tablet:
Co-administration of Tenofovir alafenamide with Cosala OD Tablet may increase the risk of kidney problems.

How to manage the interaction:
There is a possibility of interaction between Cosala OD Tablet with Tenofovir alafenamide, but they can be taken together if a doctor has prescribed them. Consult a doctor immediately if you experience increased or decreased urination, swelling, shortness of breath, bone pain, cramping in the muscles. Do not discontinue the medication without consulting a doctor.
MesalazineOmeprazole
Severe
How does the drug interact with Cosala OD Tablet:
Co-administration of omeprazole with Cosala OD Tablet can decrease the effects of Cosala OD Tablet.

How to manage the interaction:
There could be a possible interaction between Cosala OD Tablet and omeprazole, but they can be taken together if a doctor has prescribed them. Do not discontinue any medications without consulting a doctor.
MesalazineNizatidine
Severe
How does the drug interact with Cosala OD Tablet:
Co-administration of Nizatidine with Cosala OD Tablet can decrease the level or effect of Mesalamine by increasing gastric pH.

How to manage the interaction:
Although there may be a possible interaction between Cosala OD Tablet with Nizatidine, they can be taken together if a doctor has prescribed them. Do not discontinue any medications without consulting a doctor.
MesalazineIodamide
Severe
How does the drug interact with Cosala OD Tablet:
Co-administration of Iodamide with Cosala OD Tablet may increase the risk of kidney problems.

How to manage the interaction:
Although, there is a possibility of interaction between Mesalamine with Iodamine they can be taken together if a doctor has prescribed them. Consult a doctor immediately if you experience any symptoms such as swelling in feet and ankles, itchy skin, shortness of breath, urinating either too much or too little. Do not discontinue any medication without consulting a doctor.
MesalazineIomeprol
Severe
How does the drug interact with Cosala OD Tablet:
Co-administration of Iomeprol with Cosala OD Tablet may increase the risk of kidney problems.

How to manage the interaction:
Although, there is a possibility of interaction between Cosala OD Tablet and Iomeprol they can be taken together if your doctor has prescribed them. Consult a doctor immediately if you experience any symptoms such as swelling in feet and ankles, urinating either too much or too little. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a low-fat diet and eat foods rich in vitamin C, such as bell peppers, spinach, parsley, and berries, to help heal faster.
  • Include olive oil and omega-3 fatty acids.
  • Eat more fibre-rich foods such as fruits and vegetables.
  • Limit dairy intake as your body may develop difficulty digesting certain dairy products when affected with Crohn’s disease, leading to stomach cramps, diarrhoea, or stomach upset.
  • Drink plenty of water to prevent dehydration.

Habit Forming

No

Therapeutic Class

ANTI- INFLAMMATORY AGENTS

Cosala OD Tablet Substitute

Substitutes safety advice
  • INFLACOL SR TABLET

    by Others

    24.39per tablet
  • Meslo 1200 Tablet 10's

    by Others

    32.58per tablet

Author Details

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • LACTULOSE
  • ASPIRIN
  • IBUPROFEN
  • AZATHIOPRINE
  • THIOGUANINE
  • MERCAPTOPURINE

Special Advise

  • Blood and urine tests are recommended before and during the treatment with Cosala OD Tablet to monitor the functioning of the kidney, liver, and blood.

Disease/Condition Glossary

Ulcerative colitis: Ulcerative colitis is a type of chronic inflammatory bowel disease that causes inflammation of the lining of the large intestine (colon) and produces ulcers on the lining of the colon, which may cause bleeding and discharge of pus and mucus. The common symptoms include bloody stools, stomach pain, rectal pain, diarrhoea, fever, or weight loss. Additionally, it may cause other problems such as joint pain or swelling, mouth sores, skin problems, decreased appetite, or nausea. The factors involved in causing ulcerative colitis include immune disorders, environmental factors like viruses, bacteria, or antigens, which may trigger the immune system, and genes inherited from the parent.

Crohn’s disease: Crohn’s disease is a type of chronic inflammatory bowel disease that can affect any part of the gastrointestinal tract, from mouth to anus. But mostly occurs in the small intestine and large intestine. The symptoms include blood in stools, stomach cramps, tiredness, diarrhoea, fever, weight loss, or loss of appetite.

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