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  3. Cresemba 100 mg Capsule 7's

Cresemba 100 mg Capsule 7's, Pack of 7 CapsuleS
Cresemba 100 mg Capsule 7's, Pack of 7 CapsuleS
Cresemba 100 mg Capsule 7's, Pack of 7 CapsuleS
Cresemba 100 mg Capsule 7's, Pack of 7 CapsuleS
Cresemba 100 mg Capsule 7's, Pack of 7 CapsuleS
Cresemba 100 mg Capsule 7's, Pack of 7 CapsuleS
Cresemba 100 mg Capsule 7's, Pack of 7 CapsuleS
Cresemba 100 mg Capsule 7's, Pack of 7 CapsuleS
Written By Veda Maddala , M Pharmacy
Reviewed By Hari Kumar , MBBS
Non returnable*
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Whats That

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Composition :

ISAVUCONAZOLE-100MG

Manufacturer/Marketer :

Pfizer Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About CRESEMBA 100MG CAPSULES

CRESEMBA 100MG CAPSULES belongs to the class of medicines called antifungals used to treat fungal infections such as invasive aspergillosis and mucormycosis. Invasive aspergillosis is an infection caused by Aspergillus fungus. It occurs when the infection spreads from lungs to kidneys, brain, heart or skin. Mucormycosis is a rare but serious fungal infection of the skin or respiratory system that occurs in people with weakened immune systems.

CRESEMBA 100MG CAPSULES contains Isavuconazole (antifungal) that works by inhibiting the synthesis of fungal cell membranes, which are essential for their survival. Thereby, CRESEMBA 100MG CAPSULES kills or inhibits the growth of the fungus.

Take CRESEMBA 100MG CAPSULES as prescribed by your doctor. You are advised to take CRESEMBA 100MG CAPSULES for as long as your doctor has prescribed it for you based on your medical condition. Some people may experience headache, decreased appetite, drowsiness, nausea, vomiting, stomach pain, diarrhoea or chest pain. Most of these side effects of CRESEMBA 100MG CAPSULES do not require medical attention and gradually resolve over time. However, if the side effects worsen or persist, please consult your doctor.

If you are allergic to CRESEMBA 100MG CAPSULES or any other medicines, please tell your doctor. CRESEMBA 100MG CAPSULES is not recommended for children below 18 years as the safety and effectiveness were not established. If you are pregnant, it is advised to consult a doctor before using CRESEMBA 100MG CAPSULES. Avoid breastfeeding while taking CRESEMBA 100MG CAPSULES. Drive only if you are alert after taking CRESEMBA 100MG CAPSULES as it may cause drowsiness, confusion or tiredness. Avoid alcohol consumption while taking CRESEMBA 100MG CAPSULES as it may increase the risk of liver damage.

Uses of CRESEMBA 100MG CAPSULES

Invasive aspergillosis and Mucormycosis

Directions for Use

Take CRESEMBA 100MG CAPSULES with or without food as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

CRESEMBA 100MG CAPSULES contains Isavuconazole, a broad-spectrum antifungal that is effective against a wide variety of microorganisms. It inhibits the synthesis of fungal cell membranes that are essential for their survival. Thereby, CRESEMBA 100MG CAPSULES kills or stops the growth of the fungus.

Storage

Store in a cool and dry place away from sunlight
Side effects of Cresemba 100 mg Capsule
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

Drug Warnings

If you are allergic to CRESEMBA 100MG CAPSULES or any other medicines, please tell your doctor. CRESEMBA 100MG CAPSULES is not recommended for children below 18 years as the safety and effectiveness were not established. If you are pregnant, it is advised to consult a doctor before using CRESEMBA 100MG CAPSULES. Avoid breastfeeding while taking CRESEMBA 100MG CAPSULES. Drive only if you are alert after taking CRESEMBA 100MG CAPSULES as it may cause drowsiness, confusion or tiredness. Avoid alcohol consumption while taking CRESEMBA 100MG CAPSULES as it may increase the risk of liver damage. If you experience severe blistering of the eyes, mouth, skin or genitals, seek immediate medical help.

Drug-Drug Interactions

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IsavuconazolePhenobarbital
Critical
IsavuconazoleFosamprenavir
Critical

Drug-Drug Interactions

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IsavuconazolePhenobarbital
Critical
How does the drug interact with Cresemba 100 mg Capsule:
When Cresemba 100 mg Capsule is taken with Phenobarbital, may decrease the blood levels of Cresemba 100 mg Capsule, which may make Cresemba 100 mg Capsule less effective.

How to manage the interaction:
Taking Cresemba 100 mg Capsule with Phenobarbital is not recommended it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
IsavuconazoleFosamprenavir
Critical
How does the drug interact with Cresemba 100 mg Capsule:
When Fosamprenavir is taken with Cresemba 100 mg Capsule, it can increase the risk of side effects like liver damage.

How to manage the interaction:
Taking Cresemba 100 mg Capsule with Fosamprenavir is not recommended, it can be taken if prescribed by the doctor. However, if you experience nausea, vomiting, diarrhea while on therapy with these drugs, consult the doctor.
IsavuconazolePosaconazole
Critical
How does the drug interact with Cresemba 100 mg Capsule:
When Cresemba 100 mg Capsule is taken with Posaconazole, it can increase the levels of Cresemba 100 mg Capsule in the blood.

How to manage the interaction:
Although there is an interaction between Cresemba 100 mg Capsule and posaconazole, it can be taken if prescribed by the doctor. However, if you experience nausea, vomiting, diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
IsavuconazoleCisapride
Critical
How does the drug interact with Cresemba 100 mg Capsule:
When Cresemba 100 mg Capsule is taken with Cisapride, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Cresemba 100 mg Capsule with Cisapride is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
IsavuconazoleKetoconazole
Critical
How does the drug interact with Cresemba 100 mg Capsule:
Co-administration of Ketoconazole and Cresemba 100 mg Capsule can significantly increase the blood levels of Cresemba 100 mg Capsule, which may increase the risk of side effects.

How to manage the interaction:
Taking Cresemba 100 mg Capsule with Ketoconazole is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience symptoms like nausea, stomach pain, headache while on therapy with these drugs, consult the doctor. Do not discontinue any medication without consulting a doctor.
IsavuconazoleCarbamazepine
Critical
How does the drug interact with Cresemba 100 mg Capsule:
When Carbamazepine and Cresemba 100 mg Capsule are taken together, carbamazepine will reduce the effectiveness of the Cresemba 100 mg Capsule.

How to manage the interaction:
Taking Cresemba 100 mg Capsule with Carbamazepine is not recommended, it can be taken if prescribed by the doctor. Do not discontinue any medications without doctor's advice.
IsavuconazolePhenytoin
Critical
How does the drug interact with Cresemba 100 mg Capsule:
Co-administration of phenytoin and Cresemba 100 mg Capsule may significantly reduce the blood levels of Cresemba 100 mg Capsule, which may make Cresemba 100 mg Capsule less effective in treating your condition.

How to manage the interaction:
Taking Cresemba 100 mg Capsule with Phenytoin is not recommended as it can cause an interaction, consult a doctor before taking it. Do not discontinue any medication without consulting a doctor.
IsavuconazolePrimidone
Critical
How does the drug interact with Cresemba 100 mg Capsule:
Taking Cresemba 100 mg Capsule with primidone may decrease the blood levels of Cresemba 100 mg Capsule and reduce its effectiveness.

How to manage the interaction:
Taking Cresemba 100 mg Capsule with primidone is not recommended, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
IsavuconazoleItraconazole
Critical
How does the drug interact with Cresemba 100 mg Capsule:
The blood levels and effects of Cresemba 100 mg Capsule may be significantly enhanced by taking Itraconazole along with it.

How to manage the interaction:
Co-administration of Cresemba 100 mg Capsule and Itraconazole can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like nausea, vomiting, or diarrhoea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
IsavuconazoleCeritinib
Critical
How does the drug interact with Cresemba 100 mg Capsule:
Taking ceritinib with Cresemba 100 mg Capsule may significantly increase the blood levels of Cresemba 100 mg Capsule.

How to manage the interaction:
Taking Cresemba 100 mg Capsule with Ceritinib is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loose stools, yellow discoloration of skin and eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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ISAVUCONAZOLE-100MGGrapefruit and Grapefruit Juice

Drug-Food Interactions

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ISAVUCONAZOLE-100MGGrapefruit and Grapefruit Juice
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking grapefruit and grapefruit juice during Cresemba 100 mg Capsule treatment may cause an interaction. Avoid grapefruit products during treatment with Cresemba 100 mg Capsule

Diet & Lifestyle Advise

  • Try to avoid areas with a lot of dust like excavation or construction sites. If you can’t avoid it, wear an N95 mask while going to such places.
  • Clean skin injuries with soap and water, especially if they have been exposed to dust or soil to decrease the chances of developing a skin infection.
  • Bandage all wounds until they heal to prevent fungal infections.
  • Wash your hands regularly and keep your hands clean to prevent the spread of germs.
  • Avoid dusty activities and digging in the soil.
  • Wear shoes, a long-sleeved t-shirt, long pants and a mask while doing outdoor activities such as yard work, gardening or vising wooded areas to protect from fungus commonly present in the environment.
  • Maintain a diet that is low in sugar, refined carbohydrates, mould-containing foods and yeast.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS

CRESEMBA 100MG CAPSULES Substitute

Substitutes safety advice

  • Zisavel 100 mg Capsule 7's

    by Others

    ₹1105.16per tablet

  • Isavulet-100 Capsule 7's

    by Others

    ₹1142.00per tablet

  • Isacrest 100 mg Capsule 7's

    by Others

    ₹1285.57per tablet

  • Isuvaz 100 Capsule 7's

    by Others

    ₹1142.71per tablet

Product Substitutes

Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Hari Kumar

Reviewed By

Hari Kumar

MBBS

Last Updated

Aug 20, 2024 | 1:09 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

CRESEMBA 100MG CAPSULES contains Isavuconazole that works by inhibiting the synthesis of fungal cell membranes which are essential for their survival. Thereby, CRESEMBA 100MG CAPSULES kills or inhibits the growth of the fungus.

Mucormycosis is not contagious. Mucormycosis is a severe fungal infection of the skin or respiratory system that occurs in people with weakened immune system.

CRESEMBA 100MG CAPSULES may cause headache as a common side effect. However, if the condition persists or worsen, please consult a doctor.

You are not recommended to take CRESEMBA 100MG CAPSULES with ketoconazole as it may increase the levels of CRESEMBA 100MG CAPSULES in blood and increase the risk of side effects such as diarrhoea, vomiting, nausea or liver problems. However, please consult your doctor before taking CRESEMBA 100MG CAPSULES with other medicines.

You are not recommended to stop using CRESEMBA 100MG CAPSULES without consulting your doctor as it may worsen the condition or cause a recurring infection. Therefore, use CRESEMBA 100MG CAPSULES for as long as your doctor has prescribed it and if you experience any difficulty while taking CRESEMBA 100MG CAPSULES, please consult your doctor.

Drug-Drug Interactions Checker List

  • RITONAVIR
  • EFAVIRENZ
  • RIFABUTIN
  • RIFAMPICIN
  • CARBAMAZEPINE
  • PHENOBARBITAL
  • PHENYTOIN
  • KETOCONAZOLE
  • ETRAVIRINE

Special Advise

Regular blood tests are recommended while taking CRESEMBA 100MG CAPSULES to monitor liver functioning.

Disease/Condition Glossary

Invasive aspergillosis: It is an infection caused by Aspergillus fungus. It occurs when the infection spreads from the lungs to the kidneys, brain, heart or skin. It mostly occurs in people with weakened immune systems due to chemotherapy or other conditions such as cancer or AIDS. The symptoms include shortness of breath, fever, chest pain or cough (sometimes with blood).

Mucormycosis: It is a rare but serious fungal infection of the skin or respiratory system that occurs in people with weakened immune systems. If it is left untreated, it can cause death. The symptoms of respiratory infection include nasal congestion, headache, cough, fever or sinus pain. The symptoms of skin infection include redness, swelling, tenderness, blackened skin tissue, blisters or ulcers.

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