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  3. Cyclisis PF 0.05% Eye Drops 5 ml

Cyclisis PF 0.05% Eye Drops 5 ml, Pack of 1 Eye Drops
Cyclisis PF 0.05% Eye Drops 5 ml, Pack of 1 Eye Drops
Cyclisis PF 0.05% Eye Drops 5 ml, Pack of 1 Eye Drops
Cyclisis PF 0.05% Eye Drops 5 ml, Pack of 1 Eye Drops
Cyclisis PF 0.05% Eye Drops 5 ml, Pack of 1 Eye Drops
Cyclisis PF 0.05% Eye Drops 5 ml, Pack of 1 Eye Drops
Cyclisis PF 0.05% Eye Drops 5 ml, Pack of 1 Eye Drops
Cyclisis PF 0.05% Eye Drops 5 ml, Pack of 1 Eye Drops
Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
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Composition :

CYCLOSPORINE-0.5MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

OPHTHALMIC

Return Policy :

Not Returnable

Expires on or after :

About Cyclisis PF 0.05% Eye Drops 5 ml

Cyclisis PF 0.05% Eye Drops 5 ml belongs to the class of medicines called immunosuppressants used in the treatment of severe keratitis (inflammation of the cornea) in adults. Also, it is used to treat dry eyes in patients whose condition has not been improved with artificial tears. A dry eye is a common condition that occurs when tears are unable to provide sufficient moisture. 

Cyclisis PF 0.05% Eye Drops 5 ml contains Cyclosporine, which works by increasing tear production and decreasing inflammation (swelling) in the eye. 

Use Cyclisis PF 0.05% Eye Drops 5 ml as prescribed by your doctor. Cyclisis PF 0.05% Eye Drops 5 ml is only for use in eyes. You are advised to use Cyclisis PF 0.05% Eye Drops 5 ml for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience eye irritation, eye pain, watery eyes, itching in the eye, redness or swelling of the eyelid, and blurred vision using Cyclisis PF 0.05% Eye Drops 5 ml. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Please tell your doctor if you are allergic to Cyclisis PF 0.05% Eye Drops 5 ml or any other medicines. If you are pregnant or breastfeeding, please consult your doctor before using Cyclisis PF 0.05% Eye Drops 5 ml. Avoid using Cyclisis PF 0.05% Eye Drops 5 ml while you are wearing contact lenses. Drive only if your vision is clear, as Cyclisis PF 0.05% Eye Drops 5 ml may cause temporary blurred vision immediately after applying. If you have or had an eye infection, inform your doctor before using Cyclisis PF 0.05% Eye Drops 5 ml. 

Uses of Cyclisis PF 0.05% Eye Drops 5 ml

Dry eyes and severe keratitis

Directions for Use

Lie down and tilt your head backwards. Pull your lower eyelid gently with your index finger to form a pocket. Instil the number of drops as advised by the doctor into the pocket of the lower eyelid. Close your eyes for 1-2 minutes. Do not touch the tip of the container to the eye, eyelids or surrounding areas as it may contaminate Cyclisis PF 0.05% Eye Drops 5 ml. Cyclisis PF 0.05% Eye Drops 5 ml is for external use only. Do not inject Cyclisis PF 0.05% Eye Drops 5 ml.

Medicinal Benefits

Cyclisis PF 0.05% Eye Drops 5 ml contains Cyclosporine, an immunosuppressant that increases tear production and decreases inflammation (swelling) in the eye. Thus, it is used in the treatment of severe keratitis (inflammation of the cornea) and to treat dry eyes in patients whose condition has not been improved with artificial tears. 

Storage

Store in a cool and dry place away from sunlight
Side effects of Cyclisis PF 0.05% Eye Drops 5 ml
  • To the affected part, apply warm compresses to get a temporary relief.
  • Rinse your eye carefully with clean water and try to blow any dust particle that could have entered.
  • Take over the counter medication to lubricate your eye or if there is pain due to allergy to soothe the eye.
  • If there is persistent pain in your eye, consult your doctor and follow the medication immediately.
  • Eat a healthy, well-balanced diet full of vitamins, minerals, and omega-3 fatty acids to help maintain eye health.
  • Wear UV-protecting sunglasses when you are outside or in bright light.
  • Avoid touching or rubbing your eyes it may increase irritation.
  • Seek medical care if you are experiencing extreme eye pain or discomfort.
  • Your doctor might recommend eye drops to treat dry eyes, reduce inflammation, or stop irritation.
  • Use a cold, moist towel to relieve inflammation and discomfort.
  • Refrain from rubbing or touching the affected eyelid to avoid worsening the irritation.
  • Avoid allergens like pollen or pet dander that may trigger eyelid erythema.
  • Gently wash the eyelid with mild soap and water to prevent infection.
  • Drink lots of water to keep your skin and eyes moisturized.
  • Inform your doctor if you experience severe symptoms like intense pain, vision changes, or increased sensitivity to light.
  • Avoid rubbing your eyes, which can exacerbate the issue.
  • Lubricate your eyes using artificial tears or eye drops.
  • Wear sunglasses while you are out in the sun to protect your eyes from sun and wind.
  • Avoid irritants like smoke, dust, and strong chemicals.
  • Get enough rest and sleep to help your eyes recover.
  • Stay hydrated by drinking plenty of water.
  • Get plenty of rest to help your eyes recover.
  • Eat a balanced diet low in fat and rich in fruits, vegetables, and whole grains.
  • Limit spicy and seasoned foods that can irritate your eyes.
  • Avoid seafood, which can trigger allergies or infections that worsen red eye symptoms.
  • Talk to the doctor if you notice any visual disturbances.
  • Do not drive or operate machinery unless you have a clear vision.
  • Lubricate the eyes and use a warm compress to gently massage the eyes.
  • Keep your eyes protected from harmful sun rays by wearing sunglasses and a hat.
  • Rest well and eat a balanced diet.
  • Use a humidifier and increase fluid intake.
  • Eat a healthy, low-fat diet rich in whole grains, fruits, and vegetables.
  • Drink plenty of water to stay hydrated.
  • Get adequate sleep and avoid direct sunlight.
  • Follow a low-salt diet to minimize fluid retention.
  • Apply a cold compress to reduce inflammation and soothe affected areas.

Drug Warnings

Please tell your doctor if you are allergic to Cyclisis PF 0.05% Eye Drops 5 ml or any other medicines. If you are pregnant or breastfeeding, please consult a doctor. Avoid using Cyclisis PF 0.05% Eye Drops 5 ml while you are wearing contact lenses. Drive only if your vision is clear, as Cyclisis PF 0.05% Eye Drops 5 ml may cause temporary blurred vision immediately after applying. If you have or had an eye infection, inform your doctor before using Cyclisis PF 0.05% Eye Drops 5 ml. You are recommended to maintain a time gap of 15 minutes between using other eye medicines and Cyclisis PF 0.05% Eye Drops 5 ml. Discard the bottle after 4 weeks of first opening to prevent infections.

Drug-Drug Interactions

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CiclosporinCidofovir
Critical
CiclosporinPitavastatin
Critical

Drug-Drug Interactions

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CiclosporinCidofovir
Critical
How does the drug interact with Cyclisis PF 0.05% Eye Drops 5 ml:
Taking cyclosporine with cidofovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Cyclisis PF 0.05% Eye Drops 5 ml with Cidofovir is not recommended, but can be taken be together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact the doctor immediately. Do not discontinue any medications without consulting a doctor
CiclosporinPitavastatin
Critical
How does the drug interact with Cyclisis PF 0.05% Eye Drops 5 ml:
Coadministration of pitavastatin with Cyclisis PF 0.05% Eye Drops 5 ml may significantly increase the blood levels of pitavastatin which can increase the risk of side effects such as liver problems and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Pitavastatin with Cyclisis PF 0.05% Eye Drops 5 ml is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like unexpected bruising or bleeding, skin rash, itching, tiredness, nausea, vomiting, yellowing of the skin or eyes, unexplained muscular pain, tenderness, or weakness, fever, dark urine, chills, joint pain, or swelling, consult a doctor. Do not discontinue any medications without a doctor's advice.
CiclosporinBaricitinib
Critical
How does the drug interact with Cyclisis PF 0.05% Eye Drops 5 ml:
Co-administration of Baricitinib with Cyclosporine can increase the risk of infections as well as some cancers.

How to manage the interaction:
Taking Cyclisis PF 0.05% Eye Drops 5 ml with Baricitinib is not recommended as it can cause an interaction, but it can be taken together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
CiclosporinSimvastatin
Critical
How does the drug interact with Cyclisis PF 0.05% Eye Drops 5 ml:
Combining Cyclisis PF 0.05% Eye Drops 5 ml and Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver damage and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Cyclisis PF 0.05% Eye Drops 5 ml and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, and yellowing of the skin or eyes, contact the doctor immediately. Do not discontinue any medications without consulting your doctor.
CiclosporinBosentan
Critical
How does the drug interact with Cyclisis PF 0.05% Eye Drops 5 ml:
When Bosentan is taken with Cyclosporine, it may increase the risk of side effects.

How to manage the interaction:
Taking Cyclisis PF 0.05% Eye Drops 5 ml with Bosentan is not recommended, but it can be taken if prescribed by the doctor. However, if you experience any symptoms like severe headache, nausea, or an increased heart rate, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
CiclosporinEtanercept
Severe
How does the drug interact with Cyclisis PF 0.05% Eye Drops 5 ml:
When etanercept is taken with cyclosporine, it can increase the risk of infections.

How to manage the interaction:
Although taking etanercept and Cyclisis PF 0.05% Eye Drops 5 ml together can result in an interaction, it can be taken if a doctor has prescribed it. However, contact a doctor immediately if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
CiclosporinVenetoclax
Severe
How does the drug interact with Cyclisis PF 0.05% Eye Drops 5 ml:
Co-administration of venetoclax with Cyclisis PF 0.05% Eye Drops 5 ml may significantly increase the blood levels and effects of venetoclax.

How to manage the interaction:
Although there is a possible interaction between venetoclax and Cyclisis PF 0.05% Eye Drops 5 ml, they can be taken together if your doctor has prescribed them. However, contact your doctor immediately if experience any symptoms such as nausea, paleness, vomiting, diarrhea and weakness. Do not stop using any medications without talking to a doctor.
CiclosporinAliskiren
Severe
How does the drug interact with Cyclisis PF 0.05% Eye Drops 5 ml:
The combined use of aliskiren and Cyclisis PF 0.05% Eye Drops 5 ml can significantly increase the blood levels and effects of aliskiren, which may lead to low blood pressure, hyperkalemia (high potassium levels) in the body. High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythms. If you are elderly, dehydrated, or have kidney disease, diabetes, or severe heart failure, you are more prone to develop hyperkalemia while taking these medications.

How to manage the interaction:
Taking aliskiren and Cyclisis PF 0.05% Eye Drops 5 ml will lead to an interaction, they can be taken together if your doctor has prescribed them. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. It is advised to reduce intake of potassium-rich foods such as tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes, and potassium-containing salt substitutes.
CiclosporinAtazanavir
Severe
How does the drug interact with Cyclisis PF 0.05% Eye Drops 5 ml:
Using atazanavir with ciclosporine may increase the blood levels and effects of Cyclisis PF 0.05% Eye Drops 5 ml

How to manage the interaction:
Although there is a interaction between Cyclisis PF 0.05% Eye Drops 5 ml and atazanavir, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience nausea, vomiting, diarrhea, abdominal pain, dizziness, weakness, headache, shaking, fits, fever, sore throat, unusual bruising or bleeding, and increased or decreased urination. Do not discontinue any medications without consulting a doctor.
CiclosporinEdoxaban
Severe
How does the drug interact with Cyclisis PF 0.05% Eye Drops 5 ml:
Taking edoxaban and Cyclisis PF 0.05% Eye Drops 5 ml can significantly increase the blood levels of edoxaban.

How to manage the interaction:
Taking Cyclisis PF 0.05% Eye Drops 5 ml with edoxaban together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience bleeding, bruising, blood in stools or urine, dizziness, severe headache, weakness, or vomiting contact a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Use a humidifier in your room to increase moisture and avoid dry climates. 
  • Limit the time you spend in front of the television or computer.
  • If dry eyes are caused by environmental factors, wear protective eyewear during outdoor activities when it’s windy and avoid exposure to cigarette smoke. 
  • Limit wearing contact lenses and use soft contact lenses if you have dry eyes, as they are moist and allow the eye to breathe better than hard contact lenses.
  • Take omega-3-fatty acid supplements as they may be helpful in treating dry eyes. 

Habit Forming

No

Therapeutic Class

IMMUNOSUPPRESSANTS

Product Substitutes

Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 20, 2024 | 1:14 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Cyclisis PF 0.05% Eye Drops 5 ml contains Cyclosporine, which works by increasing tear production and decreasing inflammation (swelling) in the eye. Thereby, it provides a soothing effect and relieves irritation and dryness caused by decreased tear flow.

You are recommended to use Cyclisis PF 0.05% Eye Drops 5 ml after 15 minutes of using other eye medications only if advised by your doctor. Therefore, inform your doctor if you are using any other medicines before using Cyclisis PF 0.05% Eye Drops 5 ml

Cyclisis PF 0.05% Eye Drops 5 ml may cause temporary blurred vision immediately after applying. Therefore, you are recommended to wait until your vision is clear before driving or operating machinery.

You are recommended to avoid wearing contact lenses while using Cyclisis PF 0.05% Eye Drops 5 ml as it may cause eye irritation. Therefore, you are advised to remove contact lenses before applying Cyclisis PF 0.05% Eye Drops 5 ml and reinsert after 15 minutes of using Cyclisis PF 0.05% Eye Drops 5 ml. Also, inform your doctor if you experience pain, stinging or abnormal sensation in the eye after using Cyclisis PF 0.05% Eye Drops 5 ml.

You are recommended to discuss with your doctor before using eye drops containing steroids with Cyclisis PF 0.05% Eye Drops 5 ml as there is a risk of side effects if used both medicines simultaneously.

Special Advise

Regular eye examinations are recommended every 3 to 6 months to assess the effects of Cyclisis PF 0.05% Eye Drops 5 ml.

Disease/Condition Glossary

Dry eyes: A common condition occurs when tears do not provide enough moisture. Redness, pain, burning sensation, sensitivity to light, blurred vision, discomfort in the eye, watery eyes, difficulty reading or sitting in front of a computer for an extended period of time, or eyes becoming tired faster than usual are some of the symptoms.

Keratitis: Inflammation of the cornea occurs as a result of wearing contact lenses frequently, injury, diabetes, or surgery.

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