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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Whats That

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Composition :

CYTARABINE-1GM

Manufacturer/Marketer :

Fresenius Kabi India Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About CYTARINE INJECTION 1GM

CYTARINE INJECTION 1GM is an anticancer medicine used in the treatment of leukemia. Leukemia, also known as blood cancer, is a cancer of blood cells or blood-forming tissues. It causes excessive production of immature white blood cells by the bone marrow and reduces the body’s ability to fight infections. CYTARINE INJECTION 1GM is used in the treatment of different types of leukemias, such as acute non-lymphocytic leukemia, acute lymphocytic leukemia, chronic myelocytic leukemia and meningeal leukemia.

CYTARINE INJECTION 1GM contains Cytarabine, which belongs to the class of antimetabolites. It works by inhibiting the DNA polymerase enzyme responsible for DNA elongation, synthesis, and repair. In general, it inhibits the production of genetic material (DNA) in the cancer cells that are essential for the growth, repair and multiplication of cells. Thus, CYTARINE INJECTION 1GM stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes the death of cells.

CYTARINE INJECTION 1GM may cause certain side effects such as vomiting, nausea, mouth ulcers, loss of appetite, diarrhea, dark-coloured urine, stomach pain, hair loss, dizziness, weakness, and pain at the site of injection, prescribed by your doctor. Most of these side effects of CYTARINE INJECTION 1GM do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please seek medical help. A trained healthcare professional will administer CYTARINE INJECTION 1GM. Hence, do not self-administer.

If you are allergic to CYTARINE INJECTION 1GM, inform your doctor and avoid taking it. Inform your doctor about your complete medical and medication history before starting treatment with CYTARINE INJECTION 1GM. CYTARINE INJECTION 1GM is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Hence, inform your doctor if you are pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you have/had kidney or liver disease. Avoid alcohol consumption with CYTARINE INJECTION 1GM as it may increase the risk of liver damage. Avoid excessive exposure to sunlight as CYTARINE INJECTION 1GM may cause sensitivity to sunlight. You are advised to use sunscreen and wear protective clothing while going out.

Uses of CYTARINE INJECTION 1GM

Chronic myeloid leukemia, Acute lymphocytic leukemia, Acute non-lymphocytic leukemia, and meningeal leukemia.

Directions for Use

Your oncology doctor will administer CYTARINE INJECTION 1GM. Hence, do not self-administer.

Medicinal Benefits

CYTARINE INJECTION 1GM contains Cytarabine, which belongs to the class of antimetabolites. It works by inhibiting the DNA polymerase enzyme that is responsible for DNA elongation, synthesis, and repair. In general, it inhibits the production of genetic material (DNA) in the cancer cells that are essential for cell growth, repair and multiplication. Thus, CYTARINE INJECTION 1GM stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes the death of cells.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

CYTARINE INJECTION 1GM should be avoided if you are allergic to it or any other component present in it. Inform your doctor about your complete medical and medication history before starting treatment with CYTARINE INJECTION 1GM. CYTARINE INJECTION 1GM is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Hence, inform your doctor if you are pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you have/had any pre-existing liver or kidney disease. Avoid taking CYTARINE INJECTION 1GM if you are pregnant, as it may harm the foetus. Avoid alcohol consumption with CYTARINE INJECTION 1GM as it may increase the risk of liver damage. Avoid excessive exposure to sunlight as CYTARINE INJECTION 1GM may cause sensitivity to sunlight. You are advised to use sunscreen and wear protective clothing while going out. If you are about to receive any vaccinations, inform your doctor that you are taking CYTARINE INJECTION 1GM as it may cause infection.

Drug-Drug Interactions

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CytarabineCladribine
Severe
CytarabineBaricitinib
Severe

Drug-Drug Interactions

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CytarabineCladribine
Severe
How does the drug interact with Cytarine Injection 1gm:
The combined use of cladribine with Cytarine Injection 1gm can increase the risk and severity of side effects.

How to manage the interaction:
Although taking Cytarine Injection 1gm and Cladribine together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms, it's important to contact your doctor right away. These symptoms include complications, infection, fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you pee. Do not stop using any medications without a doctor's advice.
CytarabineBaricitinib
Severe
How does the drug interact with Cytarine Injection 1gm:
Coadministration of Cytarine Injection 1gm with Baricitinib can increase the risk of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between Cytarine Injection 1gm and Baricitinib, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
CytarabineKetoconazole
Severe
How does the drug interact with Cytarine Injection 1gm:
Taking Cytarine Injection 1gm with Ketoconazole can increase the risk of liver damage.

How to manage the interaction:
Although there is a possible interaction between Cytarine Injection 1gm and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, exhaustion, nausea, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor. Do not stop using any medications without talking to the doctor.
CytarabineClozapine
Severe
How does the drug interact with Cytarine Injection 1gm:
Combining Cytarine Injection 1gm with Clozapine can increase the risk of infection.

How to manage the interaction:
There may be a possibility of interaction between Cytarine Injection 1gm and Clozapine, but it can be taken if prescribed by a doctor. If you notice any of these symptoms - such as fever, sore throat, or muscle aches - contact your doctor immediately. Do not stop using any medications without talking to a doctor.
CytarabineEtanercept
Severe
How does the drug interact with Cytarine Injection 1gm:
When Etanercept is used with Cytarine Injection 1gm, the likelihood or severity of infection may increase.

How to manage the interaction:
Taking Cytarine Injection 1gm with Etanercept together can result in an interaction, but it can be taken if a doctor has advised it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
CytarabineTofacitinib
Severe
How does the drug interact with Cytarine Injection 1gm:
Taking Tofacitinib with Cytarine Injection 1gm may increase the risk of serious infection.

How to manage the interaction:
Taking Tofacitinib with Cytarine Injection 1gm together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
CytarabineThalidomide
Severe
How does the drug interact with Cytarine Injection 1gm:
Taking thalidomide together with Cytarine Injection 1gm may increase the risk of blood clots.

How to manage the interaction:
Although taking thalidomide and Cytarine Injection 1gm together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
CytarabineInfliximab
Severe
How does the drug interact with Cytarine Injection 1gm:
Combining Infliximab with Cytarine Injection 1gm can increase the risk or severity of developing serious infections.

How to manage the interaction:
Co-administration of Cytarine Injection 1gm with Infliximab can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a balanced diet including fruits and vegetables rich in nutrients and low-fat proteins like lean meats, fish and poultry.
  • Drink plenty of water daily while taking CYTARINE INJECTION 1GM as some cancer therapies may cause dehydration.
  • Exercise regularly and maintain a healthy body weight.
  • Regularly wash your hands and avoid contact with people having infections.
  • Quit smoking.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

CYTARINE INJECTION 1GM Substitute

Substitutes safety advice
  • Cytosar 1 gm Injection 10 ml

    by Others

    106.79per tablet

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

CYTARINE INJECTION 1GM contains Cytarabine, which belongs to the class of antimetabolites. It works by inhibiting the DNA polymerase enzyme that is responsible for DNA elongation, synthesis, and repair.

If you are about to receive any vaccinations, especially live vaccines such as measles, mumps, rubella and polio vaccines, it is advised to inform your doctor that you are on treatment with CYTARINE INJECTION 1GM as it may cause infections.

CYTARINE INJECTION 1GM may cause embryo-fetal toxicity. Therefore, please consult a doctor before taking CYTARINE INJECTION 1GM if you are planning to become pregnant.

Drug-Drug Interactions Checker List

  • MESALAZINE
  • OLSALAZINE
  • SULFASALAZINE
  • GENTAMICIN
  • AMIKACIN
  • CHOLERA VACCINE
  • TYPHOID VACCINE

Special Advise

  • Regular blood tests are recommended while taking CYTARINE INJECTION 1GM to monitor the number and type of cells in the blood. 
  • CYTARINE INJECTION 1GM, like other cytotoxic medicines, can cause hyperuricemia due to the fast lysis of neoplastic cells. Blood uric acid levels should be monitored and be ready to utilize any supportive or pharmacologic interventions that may be required to address this condition.

Disease/Condition Glossary

Chronic myeloid leukemia: It is a type of cancer that occurs in the bone marrow and blood. It abnormally increases the number of immature white blood cells. The symptoms include unexplained weight loss, excessive sweating, bone pain, frequent nosebleeds, heavier-than-normal periods in females, and shortness of breath. The risk factors include smoking and genetic or blood disorders.

Acute lymphocytic leukemia: It is a type of cancer that occurs in the bone marrow and blood. It increases the number of lymphocytes (a type of white blood cell). The symptoms include fever, enlarged liver, bone or joint pain, shortness of breath, weakness, and bleeding from gums or bruises.

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